Management of Iatrogenic Urorectal Fistulae in Men with Pelvic Cancer

INTRODUCTION: Urorectal fistula (URF) is a devastating complication of pelvic cancer treatments and a surgical challenge for the reconstructive surgeon. We report a series of male patients with URF resulting from pelvic cancer treatments, specifically prostate (PCa), bladder (BCa), and rectal cancer (RCa), and explore the differences and impact on outcomes between purely surgical and non-surgical treatment modalities. METHODS: Between October 2008 and June 2015, 15 male patients, aged 59-78 years (mean 67), with URF induced by pelvic cancer treatments were identified in our institutions. Patients with a history of diverticulitis, inflammatory bowel disease, or other benign conditions were excluded. We reviewed the patients' medical records for symptoms, diagnostic tests performed, type and etiology of the fistula, type of surgical reconstruction, followup, and outcomes. RESULTS: Fourteen patients underwent surgical reconstruction. One patient developed metastatic disease before URF repair and, therefore, was excluded from this study. Mean followup (FU) was 32.7 months (14-79). All patients received diverting colostomy and temporary urinary diversion. An exclusively transperineal approach was used in nine (64.3%) patients and a combined abdominoperineal in five (35.7%). Overall successful URF closure was achieved in 12 (85.7%) patients, nine (64.3%) of whom at the first reconstructive attempt, two (14.3%) after two attempts (in our institution), and one (7.1%) after three attempts (two of which elsewhere). An interposition flap was used in seven (50%) patients. Surgical reconstruction failed ultimately in two (14.3%) patients who still have a colostomy and do not wish any further reconstruction. CONCLUSIONS: Our study has several limitations, including its retrospective nature and the heterogeneity of our small patient cohort. Nonetheless, although surgical reconstruction of URF may be extremely difficult and complex in the non-surgical/energy ablation patients, its successful reconstruction is possible in most through a transperineal, or a more aggressive abdominoperineal, approach with tissue interposition in selected patients.info:eu-repo/semantics/publishedVersio

SIMULATION OF CALCIUM PHOSPHATE DEPOSITION ON STAINLESS STEEL SURFACES: A NEW APPROACH BASED ON CELLULAR AUTOMATA

Fouling caused by calcium phosphate upon heating is basically a crystallization/precipitation process, which starts with the formation of stable clusters of ions or molecules in a process called nucleation that occurs either in the bulk liquid or at the surface. The cellular automata are useful tools to model complex systems of the universe. They could be considered as a good alternative to differential equations and have been used to model many physical/biological systems. In this preliminary work, a two dimensional space was considered where the cellular automata lattice was represented as a grid of squares, with each square representing a single automaton cell. Several situations were simulated, representing the growth of the deposit on stainless steel materials for different surface energies. The results of the simulations were compared with experimental data obtained in the laboratory

Cultivo de arroz irrigado orgânico no Rio Grande do Sul.

bitstream/item/46576/1/sistema-17.pd

Qualitative understanding of the sign of t' asymmetry in the extended t-J Model and relevance for pairing properties

Numerical calculations illustrate the effect of the sign of the next nearest-neighbor hopping term t' on the 2-hole properties of the t-t'-J model. Working mainly on 2-leg ladders, in the -1.0 < t'/t < 1.0 regime, it is shown that introducing t' in the t-J model is equivalent to effectively renormalizing J, namely t' negative (positive) is equivalent to an effective t-J model with smaller (bigger) J. This effect is present even at the level of a 2x2 plaquette toy model, and was observed also in calculations on small square clusters. Analyzing the transition probabilities of a hole-pair in the plaquette toy model, it is argued that the coherent propagation of such hole-pair is enhanced by a constructive interference between both t and t' for t'>0. This interference is destructive for t'<0.Comment: 5 pages, 4 figures, to appear in PRB as a Rapid Communicatio

Biometric analysis of seeds of genotypes of physic nut (Jatropha curcas L.).

Procurou-se investigar aspectos da morfologia das sementes de diferentes genótipos de pinhão-manso, em razão da pouca literatura existente em relação aos aspectos biométrico das sementes desta espécie. O delineamento experimental utilizado foi o inteiramente casualizado, em esquema simples, sendo 15 níveis de genótipos (Diamantina, Tominaga, Paraíso, Jales, CNPAE ? C2, CNPAE ? 171, G ? 2, AGE, 167, 200, 210, 315, 316, 1501 e 8001), com quatro repetições. As avaliações foram realizadas com parcelas de 100 sementes para cada repetição, mensurando as variáveis: medida de largura em mm (LAS), comprimento em mm (COS) e massa de 100 sementes e g (MCS), de sementes de pinhão-manso. No geral, para os 15 genótipos de pinhão-manso estudados houve a formação de 3 grupos de médias distintas em relação as variáveis biométricas, destacando-se os genótipos Paraiso e Jales e os acessos CNPAE ? C2 e AGE

Compensation temperatures and exchange bias in La1.5Ca0.5CoIrO6

We report on the study of magnetic properties of the La1.5Ca0.5CoIrO6 double perovskite. Via ac magnetic susceptibility we have observed evidence of weak ferromagnetism and reentrant spin glass behavior on an antiferromagnetic matrix. Regarding the magnetic behavior as a function of temperature, we have found that the material displays up to three inversions of its magnetization, depending on the appropriate choice of the applied magnetic field. At low temperature the material exhibit exchange bias effect when it is cooled in the presence of a magnetic field. Also, our results indicate that this effect may be observed even when the system is cooled at zero field. Supported by other measurements and also by electronic structure calculations, we discuss the magnetic reversals and spontaneous exchange bias effect in terms of magnetic phase separation and magnetic frustration of Ir4+ ions located between the antiferromagnetically coupled Co ions.Comment: 10 pages, 8 figures and supplemental materia