7 research outputs found

    Key problems of seismic zoning of urban areas adjacent to the Mongolia-Siberian region (by the example of Erdenet town)

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    The first approximation approach to seismic zoning of the areas adjacent to the Mongolia-Siberian region has been followed by the example of Erdenet town. The grounds have been given for problematic stages of working: study of some regular trends of seismic setting and current level of initial seismicity of the area; identification of seismic activity areas and assessment of their seismic potential; seismic modeling of sites with the most typical soil conditions; model theoretical calculating of basic parameters of seismic effects and model zoning of the investigated area. Technically, the stages of Erdenet town case study can serve as a basis for seismic zoning of the areas of interest that are adjacent to the Mongolia-Siberian region.The work has been done under financial support of RFBR project No. 07-05- 90111.DOI: http://dx.doi.org/10.5564/pmas.v0i4.38Proceedings of the Mongolian Academy of Sciences 2007 No 4 pp.17-3

    Functional expression of GFP-linked human heart sodium channel (hH1) and subcellular localization of the alpha subunit in HEK293 cells and dog cardiac myocytes

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    Recent evidence suggests that biosynthesis of the human heart Na+ channel (hH1) protein is rapidly modulated by sympathetic interventions. However, data regarding the intracellular processing of hH1 in vivo are lacking. In this study we sought to establish a model that would allow us to study the subcellular localization of hH1 protein. Such a model could eventually help us to better understand the trafficking of hH1 in vivo and its potential role in cardiac conduction. We labeled the C-terminus of hill with the green fluorescent protein (GFP) and compared the expression of this construct (hH1-GFP) and hH1 in transfected HEK293 cells. Fusion of GFP to hH1 did not alter its electrophysiological properties. Confocal microscopy revealed that hH1-GFP was highly expressed in intracellular membrane structures. Immuno-electronmicrographs showed that transfection of hH1-GFP and hH1 induced proliferation of three types of endoplasmic reticulum (ER) membranes to accommodate the heterologously expressed proteins. Labeling with specific markers for the ER and the Golgi apparatus indicated that the intracellular channels are almost exclusively retained within the ER. Immunocytochemical labeling of the Na+ channel in dog cardiomyocytes showed strong fluorescence in the perinuclear region of the cells, a result consistent with our findings in HEK293 cells. We propose that the ER may serve as a reservoir for the cardiac Na+ channels and that the transport from the ER to the Golgi apparatus is among the rate-limiting steps for sarcolemmal expression of Na+ channels

    Velocity structure of the lithosphere on the 2003 Mongolian-Baikal transect from SV waves

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    Original Russian Text © V.V. Mordinova, A. Deschamps, T. Dugarmaa, J. DeverchĂ©re, M. Ulziibat, V.A. Sankov, A.A. Artem'ev, J. Perrot, 2007, published in Fizika Zemli, 2007, No. 2, pp. 21–32.International audienceThe S wave velocity distribution in the Earth's crust and the first two hundred kilometers of the upper mantle is inferred from data of a seismological linear network including 18 broadband stations installed in the framework of the international teleseismic experiment carried out in 2003 in the south of Siberia and in Mongolia. Models were constructed by using P-to-S received function inversion beneath each station. Vertical cross sections of S wave velocities from the surface to depths of 65 and 270 km covering the entire 1000-km profile are constructed by the linear spline interpolation of individual velocity models. The vertical sections are also represented as anomalies relative to the standard velocity model. The most intense low velocity anomalies (from −3 to −6%) in the crust and upper mantle are identified beneath the Sayan, Khamar-Daban, and Khangai highlands and the Djida fold zone and agree both with other geophysical data and with the distribution of Late Cenozoic volcanic fields. The results of this work suggest that the activation of Mongolian-Siberian highlands is largely connected with uplift of the asthenosphere to the base of the crust

    Upper mantle flow beneath and around the Hangay Dome, central Mongolia

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    International audienceMongolia represents the northernmost area affected by the India–Asia collision, and it is actively deformed along transpressive belts closely associated with large-scale strike-slip faults. The active and past mantle flow beneath this region is, however, poorly known. In order to investigate deep mantle deformation beneath central Mongolia and its relation with the surrounding major structures such as the Siberian craton, the Gobi–Altay belt and the Baikal rift, a NS-trending profile of broadband seismic stations has been deployed in the summer 2003 from the southern Siberian craton to the Gobi–Altay range, crossing the entire Hangay dome. Mantle flow is deduced from the splitting of teleseismic shear waves such as SKS phases. In eastern Mongolia, the permanent station ULN in Ulaanbaatar reveals the presence of two anisotropic layers, the upper one being oriented NE–SW, close to the trend of lithospheric structures and the lower one NW–SE, close to the trend of Eurasia absolute plate motion. Along the NS profile in central Mongolia, seismic anisotropy deduced from SKS splitting reveals a homogeneous NW–SE trending structure, fully consistent with the observations made in the Altay–Sayan in western Mongolia. The observed delay times of 1.5 to more than 2.0 s favor consistent mantle flow over large mantle thicknesses. Since the lithosphere is less than 100 km thick beneath central Mongolia and since the observed fast directions are parallel to the trend of the lithospheric structures but also close to the trend of the absolute plate motion, we propose that both the lithosphere and the asthenosphere may join their anisotropic effects beneath central Mongolia to explain the large delay times. Although GPS vectors represent the instantaneous displacement of the Earth's surface and SKS splitting the time and vertical integration of finite strain at depth, we use the opportunity of the dense geodetic measurements available in this region to discuss the anisotropy pattern in term of present-day deformation. In the Eurasia-fixed reference frame, GPS and SKS both depict a similar trend beneath central Mongolia, suggesting a lithospheric block “escaping” toward the east that could orient olivine a-axes in the upper mantle, within a transpressive tectonic regime. A different behaviour is observed in western Mongolia: the GPS vectors trend NS, close to the regional compression direction, whereas the fast SKS directions trend EW, suggesting a tectonic regime close to a mode of axial shortening, generating the development of an EW-trending foliation at depth. We therefore propose that Mongolia is a place where active and frozen lithospheric deformation may add their effects, together with the sublithospheric flow. In the three sources of anisotropy inferred, a fundamental role is played by the Siberian craton that acted as an undeformable core of the continent through time: the frozen Paleozoic and Mesozoic structures wrap around the craton, building up the fast anisotropic direction pattern; the present-day sublithospheric flow induced by the plate motion is likely deflecting around its deep roots; finally, the present-day tectonic regime appears to be controlled by the presence of the craton to the north
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