The Black Hole Mass - Galaxy Bulge Relationship for QSOs in the SDSS DR3

We investigate the relationship between black hole mass and host galaxy velocity dispersion for QSOs in Data Release 3 of the Sloan Digital Sky Survey. We derive black hole mass from the broad Hbeta line width and continuum luminosity, and the bulge stellar velocity dispersion from the [OIII] narrow line width. At higher redshifts, we use MgII and [OII] in place of Hbeta and [OIII]. For redshifts z < 0.5, our results agree with the black hole mass - bulge velocity dispersion relationship for nearby galaxies. For 0.5 < z < 1.2, this relationship appears to show evolution with redshift in the sense that the bulges are too small for their black holes. However, we find that part of this apparent trend can be attributed to observational biases, including a Malmquist bias involving the QSO luminosity. Accounting for these biases, we find ~0.2 dex evolution in the black hole mass-bulge velocity dispersion relationship between now and redshift z ~ 1.Comment: Accepted by ApJ, 15 pages, 9 figure

A variability study of the Seyfert 2 galaxy NGC 6300 with XMM-Newton

We present the results of timing analysis of the XMM-Newton observation of the Seyfert 2 galaxy NGC 6300. The hard X-ray spectrum above 2 keV consists of a Compton-thin-absorbed power law, as is often seen in Seyfert 2 galaxies. We clearly detected rapid time variability on a time scale of about 1000 s from the light curve above 2 keV. The excess variance of the time variability (sigma2_RMS) is calculated to be ~0.12, and the periodogram of the light curve is well represented by a power law function with a slope of 1.75. In contrast with previous results from Seyfert 2 nuclei, these variability characteristics are consistent with those of Seyfert 1 galaxies. This consistency suggests that NGC 6300 has a similar black hole mass and accretion properties as Seyfert 1 galaxies. Using the relation between time variability and central black hole mass by Hayashida et al. (1998), the black hole mass of NGC 6300 is estimated to be ~2.8x10^5 Mo. Taking uncertainty of this method into account, the black hole mass is less than 10^7 Mo. Taking the bolometric luminosity of 3.3x10^43 erg/s into consideration, this yields an accretion rate of > 0.03 of the Eddington value, and comparable with estimates from Seyfert 1 galaxies using this method. The time variability analysis suggests that NGC 6300 actually has a Seyfert 1 nucleus obscured by a thick matter, and more generally provides a new pillar of support for the unified model of Seyfert galaxies based on obscuration.Comment: 11 pages, 6 figures, accepted for publication in Ap

Statistical Properties of Radio Emission from the Palomar Seyfert Galaxies

We have carried out an analysis of the radio and optical properties of a statistical sample of 45 Seyfert galaxies from the Palomar spectroscopic survey of nearby galaxies. We find that the space density of bright galaxies (-22 mag <= M_{B_T} <= -18 mag) showing Seyfert activity is (1.25 +/- 0.38) X 10^{-3} Mpc^{-3}, considerably higher than found in other Seyfert samples. Host galaxy types, radio spectra, and radio source sizes are uncorrelated with Seyfert type, as predicted by the unified schemes for active galaxies. Approximately half of the detected galaxies have flat or inverted radio spectra, more than expected based on previous samples. Surprisingly, Seyfert 1 galaxies are found to have somewhat stronger radio sources than Seyfert 2 galaxies at 6 and 20 cm, particularly among the galaxies with the weakest nuclear activity. We suggest that this difference can be accommodated in the unified schemes if a minimum level of Seyfert activity is required for a radio source to emerge from the vicinity of the active nucleus. Below this level, Seyfert radio sources might be suppressed by free-free absorption associated with the nuclear torus or a compact narrow-line region, thus accounting for both the weakness of the radio emission and the preponderance of flat spectra. Alternatively, the flat spectra and weak radio sources might indicate that the weak active nuclei are fed by advection-dominated accretion disks.Comment: 18 pages using emulateapj5, 13 embedded figures, accepted by Ap

Опыт применения эксимерной лампы, оснащённой системой контроля UVB дозы, в дерматологии

Intermediate ultraviolet (UVB) therapy is considered a relatively safe method of treating skin diseases with an autoimmune component in development compared to medical drug methods, including PUVA therapy. This is due to the small depth of penetration of the rays of this wavelength range into skin, which provides a purely local effect on the human body. Excimer lamps are an alternative to the expensive excimer laser for phototherapy of psoriasis or vitiligo. However, for effective phototherapy using UVB lamps, the distance from an emitter to a patient’s skin must be considered. In this paper, we report on treatment of patients using an excimer lamp, the control unit of which is equipped with an optical system for controlling of ultraviolet radiation dose, which allows automatically calculating the time for a set UVB dose. The article describes the results of phototherapy using an excimer lamp of several cases of psoriasis, vitiligo and other forms of dermatitis with a good therapeutic and cosmetic effect. When using an excimer lamp, not a single case of exacerbation of dermatological diseases was established.UVB терапия считается относительно безопасным способом лечения кожных заболеваний с аутоиммунным компонентом в развитии в сравнении с медикаментозными методами, включая ПУВА терапию. Это обусловлено малой глубиной проникновения лучей данного диапазона длин волн в кожный покров, что обеспечивает сугубо локальное воздействие на организм человека. Эксимерные лампы являются альтернативой дорогостоящему эксимерному лазеру при фототерапии псориаза и витилиго. Однако для эффективной фототерапии с использованием UVB ламп необходимо учитывать расстояние от излучателя до кожи пациента. В данной работе сообщается о лечении больных с использованием эксимерной лампы, блок управления которой снабжён оптической системой контроля дозы ультрафиолетового излучения, что позволяет автоматически производить расчёт времени сеанса для заданной UVB дозы. В статье приведено описание результатов фотолечения с использованием эксимерной лампы нескольких случаев псориаза, витилиго и других форм дерматитов с хорошим терапевтическим и косметическим эффектом. При использовании эксимерной лампы не установлено ни одного случая обострения дерматологических заболеваний

Методика фьюжн-биопсии, или виртуальной сонографии в режиме реального времени (RVS), – первый опыт верификации зон контрастирования молочной железы под совмещенным УЗ/МР-контролем

One of the actual problems of oncology is the early diagnosis of breast cancer. However, there are some difficulties not only in diagnostic but also in the verification of lesions. Image-guided cor-biopsy nowadays became the gold standard for verification of non-palpable breast lesions. The main issue is to choose the method of visualization. According to up-to-date recommendations, there is no universal method with all requirements (high visualization quality, convenience, and accessibility for biopsy). Fusion-biopsy or virtual real-time sonography can combine MRI diagnostic potential and facility of USAim: to leverage the technique of fusion biopsy under combined ultrasound/MR control for verification of breast lesions identified only on MRI and occult on MG and US.Methods. 30 high-risk patients, who had pathological breast lesions detected by diagnostic CE-MRI, classified as BI-RADS 4, 5 yet occult on the other visualization methods were enrolled in the study. All patients underwent supine MRI prebiopsy examination, real-time virtual sonography of the lesions, image-guided biopsy or excisional biopsy, histopathologic examination.Results. The breast fusion-biopsy method was developed based on up-to-date scientific publications and optimized for the technical equipment of N.N. Petrov National Medicine Research Center of Oncology. According to the designed protocol of examination, there were the following steps: interpretation of breast CE-MRI in the standard prone position for breast lesion detection, prebiopsy CE-MRI performed in the supine position, real-time virtual sonography for comparison of breast MRI and US, histopathologic examination.Conclusion. Being one of the perspectives methodic of morphological verification Fusion-biopsy might become a more common procedure in breast lesions diagnostics. The simplicity of US-guided biopsy and high MRI breast diagnostic sensitivity are combined in fusion-biopsy technology.К актуальным проблемам современной онкологии относится ранняя диагностика рака молочной железы. Однако сложности возникают не только на этапе диагностики, но и при верификации процесса. Взятие материала путем чрескожной трепанобиопсии под контролем медицинской визуализации является “золотым стандартом” верификации непальпируемых образований молочной железы, ключевым моментом является выбор метода визуального контроля. Однако на данный момент нет универсальной методики, обладающей всеми требованиями: хорошей визуализацией очага, удобством и доступностью выполнения биопсии. Фьюжн-биопсия, или виртуальная сонография в режиме реального времени, смогла совместить диагностические преимущества МРТ и доступность метода УЗИ.Цель исследования: оптимизировать методику фьюжн-биопсии под совмещенным УЗ/МР-контролем для верификации патологических образований молочной железы, выявленных по результатам МРТ и оккультных при УЗИ и МГ.Материал и методы. В исследование вошли данные 30 пациенток с отягощенным онкологическим анамнезом и выявленными патологическими очагами в молочных железах по результатам МРТ с динамическим контрастным усилением (ДКУ) (категория BI-RADS 4, 5) и оккультными при МГ УЗИ. Всем пациентам выполняли предбиопсийную МР-разметку, сопоставление изображений МРТ и УЗИ в режиме реального времени, трепанобиопсию патологического очага или эксцизионную биопсию с последующим морфологическим исследованием.Результаты. Методика проведения фьюжн-биопсии молочной железы была отработана на основании научных публикаций и оптимизирована с учетом технологического оснащения НМИЦ онкологии им. Н.Н. Петрова. Был разработан алгоритм выполнения процедуры, включающий следующие этапы: оценка “диагностической” МРТ молочной железы с ДКУ (в пронпозиции) для оценки изменений молочных желез, выявления патологического очага; подготовительный этап – предбиопсийная МР-разметка (в позиции супинации) с МР-контрастными метками; сопоставление на ультразвуковом аппарате изображений МРТ и УЗИ; выполнение трепанобиопсии; гистологическое исследование.Заключение. Фьюжн-биопсия является перспективной методикой забора гистологического материала, которая может получить широкое распространение в диагностике патологических образований молочной железы. Данная методика объединяет в себе простоту использования УЗИ как метода визуального контроля при выполнении биопсии патологических изменений и высокую чувствительность МРТ при диагностике патологии молочных желез

БИОПСИЯ СИГНАЛЬНЫХ ЛИМФАТИЧЕСКИХ УЗЛОВ ПРИ РАКЕ МОЛОЧНОЙ ЖЕЛЕЗЫ

За последние десятилетия в хирургическом лечении рака молочной железы появилась тенденция к органосохраняющему и все менее травматичному и калечащему этапу в многоступенчатой терапии этого заболевания. Выполнение подмышечной лимфодиссекции часто сопровождается такими осложнениями, как лимфостаз верхних конечностей, ограничение подвижности и болевые ощущения плечевого сустава, что, в ряде случаев, ведет к инвалидизации, при излечении от рака

Nationwide trends of clinical characteristics and economic burden of emergency department visits due to acute ischemic stroke

Mark Stuntz, Katsiaryna Busko, Shumaila Irshad, Taylor Paige, Veranika Razhkova, Tim Coan Deerfield Institute, New York, NY, USA Abstract: We aimed to provide estimates of the volume and associated charges of acute ischemic stroke (AIS) visits in the US, as well as to assess predictors of patient disposition following an emergency department (ED) visit for AIS. Our study was conducted using the 2010&ndash;2013 data from the Nationwide Emergency Department Sample. We identified adult visits with AIS as the primary diagnosis. A generalized linear model was used to calculate mean charges per visit after adjusting for covariates. Multinomial logistic regression was used to assess predictors of patient disposition following an ED visit for AIS. The national incidence did not appreciably change over time, increasing from 26.4 to 27.0 visits per 10,000 adults. Adjusted mean charges per event were highest in the West, increasing from $3,761 in 2010 to$4,575 in 2013. Multinomial logistic regression showed that older age was associated with increased likelihood of both hospital admission and mortality in the ED, while male sex was associated with lower odds of mortality in the ED. Despite improvements in primary and secondary prevention of cardiovascular disease, AIS remains a significant burden on the health care system with a high volume of ED visits and increasing charges for care. Keywords: epidemiology, ischemic, stroke, patient disposition, hospital charge

Experience of using an excimer lamp equipped with UVB dose control system in dermatology

Intermediate ultraviolet (UVB) therapy is considered a relatively safe method of treating skin diseases with an autoimmune component in development compared to medical drug methods, including PUVA therapy. This is due to the small depth of penetration of the rays of this wavelength range into skin, which provides a purely local effect on the human body. Excimer lamps are an alternative to the expensive excimer laser for phototherapy of psoriasis or vitiligo. However, for effective phototherapy using UVB lamps, the distance from an emitter to a patient’s skin must be considered. In this paper, we report on treatment of patients using an excimer lamp, the control unit of which is equipped with an optical system for controlling of ultraviolet radiation dose, which allows automatically calculating the time for a set UVB dose. The article describes the results of phototherapy using an excimer lamp of several cases of psoriasis, vitiligo and other forms of dermatitis with a good therapeutic and cosmetic effect. When using an excimer lamp, not a single case of exacerbation of dermatological diseases was established