2,218 research outputs found
Annual Report 2022 - Institute of Resource Ecology
The Institute of Resource Ecology (IRE) is one of the ten institutes of the Helmholtz-Zentrum Dresden – Rossendorf (HZDR). Our research activities are mainly integrated into the program “Nuclear Waste Management, Safety and Ra-diation Research (NUSAFE)” of the Helmholtz Association (HGF) and focus on the topics “Safety of Nuclear Waste Disposal” and “Safety Research for Nuclear Reactors”. The program NUSAFE, and therefore all work which is done at IRE, belong to the research field “Energy” of the HGF
Annual Report 2013 - Institute of Resource Ecology
The Institute of Resource Ecology (IRE) ISone of the eight institutes of the Helmholtz-Zentrum Dresden-Rossendorf (HZDR). The Research activities are mainly integrated into the program “Nuclear Safety Research (NUSAFE)” of the Helmholtz Association (HGF) and focused on the topics “Safety of Nuclear Waste Disposal” and “Safety Research for Nuclear Reactors”.
Additionally, various activities have been started investigating chemical and environmental aspects of processing and recycling of strategic metals, namely rare earth elements. These activities are located in the HGF program “Energy Efficiency, Materials and Resources (EMR)”. Both programs, and therefore all work which is done at IRE, belong to the research sector “Energy” of the HGF.
The research objectives are the protection of humans and the environment from hazards caused by pollutants resulting from technical processes that produce energy and raw materials. Treating technology and ecology as a unity is the major scientific challenge in assuring the safety of technical processes and gaining their public acceptance. Namely, we investigate the ecological risks exerted by radioactive and non-radioactive metals in the context of nuclear waste disposal, the production of energy in nuclear power plants and in processes along the value chain of metalliferous raw materials. A common goal is to generate better understanding about the dominating processes essential for metal mobilization and immobilization on the molecular level. This in turn enables us to assess the macroscopic phenomena, including models, codes and data for predictive calculations, which determine the transport and distribution of contaminants in the environment
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Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration.
Recessive Stargardt disease (STGD1) is an inherited blinding disorder caused by mutations in the Abca4 gene. ABCA4 is a flippase in photoreceptor outer segments (OS) that translocates retinaldehyde conjugated to phosphatidylethanolamine across OS disc membranes. Loss of ABCA4 in Abca4 -/- mice and STGD1 patients causes buildup of lipofuscin in the retinal pigment epithelium (RPE) and degeneration of photoreceptors, leading to blindness. No effective treatment currently exists for STGD1. Here we show by several approaches that ABCA4 is additionally expressed in RPE cells. (i) By in situ hybridization analysis and by RNA-sequencing analysis, we show the Abca4 mRNA is expressed in human and mouse RPE cells. (ii) By quantitative immunoblotting, we show that the level of ABCA4 protein in homogenates of wild-type mouse RPE is about 1% of the level in neural retina homogenates. (iii) ABCA4 immunofluorescence is present in RPE cells of wild-type and Mertk -/- but not Abca4 -/- mouse retina sections, where it colocalizes with endolysosomal proteins. To elucidate the role of ABCA4 in RPE cells, we generated a line of genetically modified mice that express ABCA4 in RPE cells but not in photoreceptors. Mice from this line on the Abca4 -/- background showed partial rescue of photoreceptor degeneration and decreased lipofuscin accumulation compared with nontransgenic Abca4 -/- mice. We propose that ABCA4 functions to recycle retinaldehyde released during proteolysis of rhodopsin in RPE endolysosomes following daily phagocytosis of distal photoreceptor OS. ABCA4 deficiency in the RPE may play a role in the pathogenesis of STGD1
Spin-triplet superconductivity in quasi-one dimension
We consider a system with electron-phonon interaction, antiferromagnetic
fluctuations and disconnected open Fermi surfaces. The existence of odd-parity
superconductivity in this circumstance is shown for the first time. If it is
applied to the quasi-one-dimensional systems like the organic conductors
(TMTSF)_2X we obtain spin-triplet superconductivity with nodeless gap. Our
result is also valid in higher dimensions(2d and 3d).Comment: 2 page
Shifts of the nuclear resonance in the vortex lattice in YBaCuO
The NMR and NQR spectra of Cu in the CuO plane of
YBaCuO in the superconducting state are discussed in terms of the
phenomenological theory of Ginzburg-Landau type extended to lower temperatures.
We show that the observed spectra, Kumagai {\em et al.}, PRB {\bf 63}, 144502
(2001), can be explained by a standard theory of the Bernoulli potential with
the charge transfer between CuO planes and CuO chains assumed.Comment: 11 pages 7 figure
Comments on the d-wave pairing mechanism for cuprate high superconductors: Higher is different?
The question of pairing glue for the cuprate superconductors (SC)is revisited
and its determination through the angle resolved photo-emission spectroscopy
(ARPES) is discussed in detail. There are two schools of thoughts about the
pairing glue question: One argues that superconductivity in the cuprates
emerges out of doping the spin singlet resonating valence bond (RVB) state.
Since singlet pairs are already formed in the RVB state there is no need for
additional boson glue to pair the electrons. The other instead suggests that
the d-wave pairs are mediated by the collective bosons like the conventional
low SC with the alteration that the phonons are replaced by another kind
of bosons ranging from the antiferromagnetic (AF) to loop current fluctuations.
An approach to resolve this dispute is to determine the frequency and momentum
dependences of the diagonal and off-diagonal self-energies directly from
experiments like the McMillan-Rowell procedure for the conventional SC. In that
a simple d-wave BCS theory describes superconducting properties of the cuprates
well, the Eliashberg analysis of well designed high resolution experimental
data will yield the crucial frequency and momentum dependences of the
self-energies. This line of approach using ARPES are discussed in more detail
in this review, and some remaining problems are commented.Comment: Invited review article published in the Journal of Korean Physical
Society; several typos corrected and a few comments and references adde
Electrostatic potential in a superconductor
The electrostatic potential in a superconductor is studied. To this end
Bardeen's extension of the Ginzburg-Landau theory to low temperatures is used
to derive three Ginzburg-Landau equations - the Maxwell equation for the vector
potential, the Schroedinger equation for the wave function and the Poisson
equation for the electrostatic potential. The electrostatic and the
thermodynamic potential compensate each other to a great extent resulting into
an effective potential acting on the superconducting condensate. For the
Abrikosov vortex lattice in Niobium, numerical solutions are presented and the
different contributions to the electrostatic potential and the related charge
distribution are discussed.Comment: 19 pages, 11 figure
Patenting and licensing of university research: promoting innovation or undermining academic values?
Since the 1980s in the US and the 1990s in Europe, patenting and licensing activities by universities have massively increased. This is strongly encouraged by governments throughout the Western world. Many regard academic patenting as essential to achieve 'knowledge transfer' from academia to industry. This trend has far-reaching consequences for access to the fruits of academic research and so the question arises whether the current policies are indeed promoting innovation or whether they are instead a symptom of a pro-intellectual property (IP) culture which is blind to adverse effects. Addressing this question requires both empirical analysis (how real is the link between academic patenting and licensing and 'development' of academic research by industry?) and normative assessment (which justifications are given for the current policies and to what extent do they threaten important academic values?). After illustrating the major rise of academic patenting and licensing in the US and Europe and commenting on the increasing trend of 'upstream' patenting and the focus on exclusive as opposed to non-exclusive licences, this paper will discuss five negative effects of these trends. Subsequently, the question as to why policymakers seem to ignore these adverse effects will be addressed. Finally, a number of proposals for improving university policies will be made
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Pseudorapidity Dependence of Particle Production and Elliptic Flow in Asymmetric Nuclear Collisions of p+Al, p+Au, d+Au, and ^{3}He+Au at sqrt[s_{NN}]=200  GeV.
Asymmetric nuclear collisions of p+Al, p+Au, d+Au, and ^{3}He+Au at sqrt[s_{NN}]=200  GeV provide an excellent laboratory for understanding particle production, as well as exploring interactions among these particles after their initial creation in the collision. We present measurements of charged hadron production dN_{ch}/dη in all such collision systems over a broad pseudorapidity range and as a function of collision multiplicity. A simple wounded quark model is remarkably successful at describing the full data set. We also measure the elliptic flow v_{2} over a similarly broad pseudorapidity range. These measurements provide key constraints on models of particle emission and their translation into flow
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