Book Review: Yasumoto Minoru, The Rise of a Victorian Ironopolis: Middlesbrough and Regional Industrialization. Woodbridge: Boydell Press, 2011. xv + 230pp. 5 plates. 119 figures and tables. Bibliography. £60.00.

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Complete recovery from anxiety disorders following Cognitive Behavioural Therapy in children and adolescents: a meta analysis

Cognitive Behavior Therapy (CBT) is a well-established treatment for childhood anxiety disorders. Meta-analyses have concluded that approximately 60% of children recover following treatment, however these include studies using a broad range of diagnostic indices to assess outcomes including whether children are free of the one anxiety disorder that causes most interference (i.e. the primary anxiety disorder) or whether children are free of all anxiety disorders. We conducted a meta-analysis to establish the efficacy of CBT in terms of absence of all anxiety disorders. Where available we compared this rate to outcomes based on absence of primary disorder. Of 56 published randomized controlled trials, 19 provided data on recovery from all anxiety disorders (n = 635 CBT, n = 450 control participants). There was significant heterogeneity across those studies with available data and full recovery rates varied from 47.6 to 66.4% among children without autistic spectrum conditions (ASC) and 12.2 to 36.7% for children with ASC following treatment, compared to up to 20.6% and 21.3% recovery in waitlist and active treatment comparisons. The lack of consistency in diagnostic outcomes highlights the urgent need for consensus on reporting in future RCTs of childhood anxiety disorders for the meaningful synthesis of data going forwards

A quantum study of multi-bit phase coding for optical storage

We propose a scheme which encodes information in both the longitudinal and spatial transverse phases of a continuous-wave optical beam. A split detector-based interferometric scheme is then introduced to optimally detect both encoded phase signals. In contrast to present-day optical storage devices, our phase coding scheme has an information storage capacity which scales with the power of the read-out optical beam. We analyse the maximum number of encoding possibilities at the shot noise limit. In addition, we show that using squeezed light, the shot noise limit can be overcome and the number of encoding possibilities increased. We discuss a possible application of our phase coding scheme for increasing the capacities of optical storage devices.Comment: 8 pages, 7 figures (Please email author for a PDF file if the manuscript does not turn out properly

Quantum limited particle sensing in optical tweezers

Particle sensing in optical tweezers systems provides information on the position, velocity and force of the specimen particles. The conventional quadrant detection scheme is applied ubiquitously in optical tweezers experiments to quantify these parameters. In this paper we show that quadrant detection is non-optimal for particle sensing in optical tweezers and propose an alternative optimal particle sensing scheme based on spatial homodyne detection. A formalism for particle sensing in terms of transverse spatial modes is developed and numerical simulations of the efficacy of both quadrant and spatial homodyne detection are shown. We demonstrate that an order of magnitude improvement in particle sensing sensitivity can be achieved using spatial homodyne over quadrant detection.Comment: Submitted to Biophys

New insights into ultraluminous X-ray sources from deep XMM-Newton observations

The controversy over whether ultraluminous X-ray sources (ULXs) contain a new intermediate-mass class of black holes (IMBHs) remains unresolved. We present new analyses of the deepest XMM-Newton observations of ULXs that address their underlying nature. We examine both empirical and physical modelling of the X-ray spectra of a sample of thirteen of the highest quality ULX datasets, and find that there are anomalies in modelling ULXs as accreting IMBHs with properties simply scaled-up from Galactic black holes. Most notably, spectral curvature above 2 keV in several sources implies the presence of an optically-thick, cool corona. We also present a new analysis of a 100 ks observation of Holmberg II X-1, in which a rigorous analysis of the temporal data limits the mass of its black hole to no more than 100 solar masses. We argue that a combination of these results points towards many (though not necessarily all) ULXs containing black holes that are at most a few 10s of solar mass in size.Comment: 5 pages, 2 figures, to appear in the proceedings of "The X-ray Universe 2005", San Lorenzo de El Escorial (Spain), 26-30 September 200