Interview investigation of insecure attachment styles as mediators between poor childhood care and schizophrenia-spectrum phenomenology

Background Insecure attachment styles have received theoretical attention and some initial empirical support as mediators between childhood adverse experiences and psychotic phenomena; however, further specificity needs investigating. The present interview study aimed to examine (i) whether two forms of poor childhood care, namely parental antipathy and role reversal, were associated with subclinical positive and negative symptoms and schizophrenia-spectrum personality disorder (PD) traits, and (ii) whether such associations were mediated by specific insecure attachment styles. Method A total of 214 nonclinical young adults were interviewed for subclinical symptoms (Comprehensive Assessment of At-Risk Mental States), schizophrenia-spectrum PDs (Structured Clinical Interview for DSM-IV Axis II Disorders), poor childhood care (Childhood Experience of Care and Abuse Interview), and attachment style (Attachment Style Interview). Participants also completed the Beck Depression Inventory-II and all the analyses were conducted partialling out the effects of depressive symptoms. Results Both parental antipathy and role reversal were associated with subclinical positive symptoms and with paranoid and schizotypal PD traits. Role reversal was also associated with subclinical negative symptoms. Angry-dismissive attachment mediated associations between antipathy and subclinical positive symptoms and both angry-dismissive and enmeshed attachment mediated associations of antipathy with paranoid and schizotypal PD traits. Enmeshed attachment mediated associations of role reversal with paranoid and schizotypal PD traits. Conclusions Attachment theory can inform lifespan models of how adverse developmental environments may increase the risk for psychosis. Insecure attachment provides a promising mechanism for understanding the development of schizophrenia-spectrum phenomenology and may offer a useful target for prophylactic intervention

Interview investigation of insecure attachment styles as mediators between poor childhood care and schizophrenia-spectrum phenomenology

Background Insecure attachment styles have received theoretical attention and some initial empirical support as mediators between childhood adverse experiences and psychotic phenomena; however, further specificity needs investigating. The present interview study aimed to examine (i) whether two forms of poor childhood care, namely parental antipathy and role reversal, were associated with subclinical positive and negative symptoms and schizophrenia-spectrum personality disorder (PD) traits, and (ii) whether such associations were mediated by specific insecure attachment styles. Method A total of 214 nonclinical young adults were interviewed for subclinical symptoms (Comprehensive Assessment of At-Risk Mental States), schizophrenia-spectrum PDs (Structured Clinical Interview for DSM-IV Axis II Disorders), poor childhood care (Childhood Experience of Care and Abuse Interview), and attachment style (Attachment Style Interview). Participants also completed the Beck Depression Inventory-II and all the analyses were conducted partialling out the effects of depressive symptoms. Results Both parental antipathy and role reversal were associated with subclinical positive symptoms and with paranoid and schizotypal PD traits. Role reversal was also associated with subclinical negative symptoms. Angry-dismissive attachment mediated associations between antipathy and subclinical positive symptoms and both angry-dismissive and enmeshed attachment mediated associations of antipathy with paranoid and schizotypal PD traits. Enmeshed attachment mediated associations of role reversal with paranoid and schizotypal PD traits. Conclusions Attachment theory can inform lifespan models of how adverse developmental environments may increase the risk for psychosis. Insecure attachment provides a promising mechanism for understanding the development of schizophrenia-spectrum phenomenology and may offer a useful target for prophylactic intervention

The role of stress-regulation genes in moderating the association of stress and daily-life psychotic experiences

The interaction of single nucleotide polymorphisms with both distal and proximal environmental factors across the extended psychosis phenotype is understudied. This study examined (i) the interaction of relevant SNPs with both early-life adversity and proximal (momentary) stress on psychotic experiences (PEs) in an extended psychosis sample; and (ii) differences between early-psychosis and non-clinical groups for these interactions.status: publishe

Evolution of the riverine nutrient export to the Tropical Atlantic over the last 15 years: is there a link with Sargassum proliferation?

International audienceThe Tropical Atlantic is facing a massive proliferation of Sargassum since 2011, with severe environmental and socioeconomic impacts. As a contribution to this proliferation, an increase in nutrient inputs from the tropical rivers, in response to climate and land use changes or increasing urbanization, has been often suggested and widely reported in the scientific and public literature. Here we discuss whether changes in river nutrient inputs could contribute to Sargassum proliferation in the recent years or drive its seasonal cycle. Using long-term in situ and satellite measurements of discharge, dissolved and particulate nutrients of the three world largest rivers (Amazon, Orinoco, Congo), we do not find clear evidences that nutrient fluxes may have massively increased over the last 15 years. Moreover, focusing on the "Sargassum year 2017", we estimate that along the year only 10% of the Sargassum biomass occurred in regions under river plume influence. While deforestation and pollution are a reality of great concern, our results corroborate recent findings that hydrological changes are not the first order drivers of Sargassum proliferation. Besides, satellite observations suggest that the major Atlantic river plumes suffered a decrease of phytoplankton biomass in the last two decades. Reconciling these observations requires a better understanding of the nutrient sources that sustain Sargassum and phytoplankton growth in the regio

A numerical study of the circulation and monthly-to-seasonal variability in the Caribbean Sea: the role of Caribbean eddies

This study examines the circulation and associated monthly-to-seasonal variability in the Caribbean Sea using a regional ocean circulation model. The model domain covers the region between 99.0 and 54.0°W and between 8.0 and 30.3°N, with a horizontal resolution of 1/6°. The ocean circulation model is driven by 6-hourly atmospheric reanalysis data from the National Center for Environmental Prediction and boundary forcing extracted from 5-day global ocean reanalysis data produced by Smith et al. (Mercator Newsletter 36:39–49, 2010), and integrated for 7 years. A comparison of model results with observations demonstrates that the regional ocean circulation model has skill in simulating circulation and associated variability in the study region. Analysis of the model results, as well as a companion model run that uses steady annual mean forcing, illustrates the role of Caribbean eddies for driving monthly-to-seasonal circulation variability in the model. It is found that vertically integrated transport between Nicaragua and Jamaica is influenced by the interaction between the density perturbations associated with Caribbean eddies and the Nicaraguan Ridge. The impact of Caribbean eddies squeezing through the Yucatan Channel is also discussed