655 research outputs found
Reducing pup litter size alters early postnatal calcium homeostasis and programs adverse adult cardiovascular and bone health in male rats
The in utero and early postnatal environments play essential roles in offspring growth and development. Standardizing or reducing pup litter size can independently compromise long-term health likely due to altered milk quality, thus limiting translational potential. This study investigated the effect reducing litter size has on milk quality and offspring outcomes. On gestation day 18, dams underwent sham or bilateral uterine vessel ligation surgery to generate dams with normal (Control) and altered (Restricted) milk quality/composition. At birth, pups were cross-fostered onto separate dams with either an unadjusted or reduced litter size. Plasma parathyroid hormone-related protein was increased in Reduced litter pups, whereas ionic calcium and total body calcium were decreased. These data suggest Reduced litter pups have dysregulated calcium homeostasis in early postnatal life, which may impair bone mineralization decreasing adult bone bending strength. Dams suckling Reduced litter pups had increased milk long-chain monounsaturated fatty acid and omega-3 docosahexaenoic acid. Reduced litter pups suckled by Normal milk quality/composition dams had increased milk omega-6 linoleic and arachidonic acids. Reduced litter male adult offspring had elevated blood pressure. This study highlights care must be taken when interpreting data from research that alters litter size as it may mask subtle cardiometabolic health effects.Jessica F. Briffa, Rachael O’Dowd, Tania Romano, Beverly S. Muhlhausler, Karen M. Moritz and Mary E. Wlode
Expanding the parameters of academia
This paper draws on qualitative data gathered from two studies funded by the UK Leadership Foundation for Higher Education to examine the expansion of academic identities in higher education. It builds on Whitchurch’s earlier work, which focused primarily on professional staff, to suggest that the emergence of broadly based projects such as widening participation, learning support and community partnership is also impacting on academic identities. Thus, academic as well as professional staff are increasingly likely to work in multi-professional teams across a variety of constituencies, as well as with external partners, and the binary distinction between ‘academic’ and ‘non-academic’ roles and activities is no longer clear-cut. Moreover, there is evidence from the studies of an intentionality about deviations from mainstream academic career routes among respondents who could have gone either way. Consideration is therefore given to factors that influence individuals to work in more project-oriented areas, as well as to variables that affect ways in which these roles and identities develop. Finally, three models of academically oriented project activity are identified, and the implications of an expansion of academic identities are reviewed
Evidence of B0 --> rho0 pi0
We present the first evidence of the decay B0 --> rho0 pi0, using 140fb^-1 of
data collected at the Upsilon(4S) resonance with the Belle detector at the KEKB
asymmetric e+e- collider. We detect a signal with a significance of 3.5
standard deviations, and measure the branching fraction to be Br(B0 ->- rho0
pi0) = (5.1 +/- 1.6(stat) +/- 0.9(syst))*10^-6.Comment: RevTex4, 5 pages, 4 figures, submitted to Phys.Rev.Let
Evidence for Direct CP Violation in B0 -> K+- pi-+ Decays
We report evidence for direct CP violation in the decay B0 -> K+-pi-+ with
253/fb of data collected with the Belle detector at the KEKB e+e- collider.
Using 275 million B B_bar pairs we observe a B -> K+-pi-+ signal with 2140+-53
events. The measured CP violating asymmetry is Acp(K+-pi-+) = -0.101+-0.025
(stat)+-0.005 (syst), corresponding to a significance of 3.9 sigma including
systematics. We also search for CP violation in the decays B+- -> K+-pi0 and
B+- -> pi+-pi0. The measured CP violating asymmetries are Acp(K+-pi0) =
0.04+-0.05(stat)+-0.02(syst) and Acp(pi+-pi0) = -0.02+-0.10(stat)+-0.01(syst),
corresponding to the intervals -0.05 < Acp(K+-pi0) < 0.13 and
-0.18<Acp(pi+-pi0)<0.14 at 90% confidence level.Comment: 9 pages, 3 figures. submitted to Physical Review Letter
Observation of exotic meson production in the reaction at 18 GeV/c
An amplitude analysis of an exclusive sample of 5765 events from the reaction
at 18 GeV/c is described. The
production is dominated by natural parity exchange and by
three partial waves: those with and . A
mass-dependent analysis of the partial-wave amplitudes indicates the production
of the meson as well as the meson, observed for the
first time decaying to . The dominant, exotic
(non- partial wave is shown to be resonant with a mass of
GeV/c^2 and a width of GeV/c^2 . This exotic state, the , is produced with a
dependence which is different from that of the meson, indicating
differences between the production mechanisms for the two states.Comment: 5 pages with 4 figure
Asymmetry, realised volatility and stock return risk estimates
In this paper we estimate minimum capital risk requirements for short and long positions with three investment horizons, using the traditional GARCH model and two other GARCH-type models that incorporate the possibility of asymmetric responses of volatility to price changes. We also address the problem of the extremely high estimated persistence of the GARCH model to generate observed volatility patterns by including realised volatility as an explanatory variable into the model’s variance equation. The results suggest that the inclusion of realised volatility improves the GARCH forecastability as well as its ability to calculate accurate minimum capital risk requirements and makes it quite competitive when compared with asymmetric conditional heteroscedastic models such as the GJR and the EGARCH.info:eu-repo/semantics/publishedVersio
Partial-wave analysis of the eta pi+ pi- system produced in the reaction pi-p --> eta pi+ pi- n at 18 GeV/c
A partial-wave analysis of 9082 eta pi+ pi- n events produced in the reaction
pi- p --> eta pi+ pi- n at 18.3 GeV/c has been carried out using data from
experiment 852 at Brookhaven National Laboratory. The data are dominated by
J^{PC} = 0^{-+} partial waves consistent with observation of the eta(1295) and
the eta(1440). The mass and width of the eta(1295) were determined to be 1282
+- 5 MeV and 66 +- 13 Mev respectively while the eta(1440) was observed with a
mass of 1404 +- 6 MeV and width of 80 +- 21 MeV. Other partial waves of
importance include the 1++ and the 1+- waves. Results of the partial wave
analysis are combined with results of other experiments to estimate f1(1285)
branching fractions. These values are considerably different from current
values determined without the aid of amplitude analyses.Comment: 22 pages, 8 figure
An Improved Measurement of Mixing-induced CP Violation in the Neutral B Meson System
We present an improved measurement of the standard model CP violation
parameter sin2phi_1 (also known as sin2beta) based on a sample of 85 times 10^6
B Bbar pairs collected at the Upsilon(4S) resonance with the Belle detector at
the KEKB asymmetric-energy e+e- collider. One neutral B meson is reconstructed
in a J/psi K_S, psi(2S) K_S, chi_{c1} K_S, eta_c K_S, J/psi K^{*0}, or J/psi
K_L CP-eigenstate decay channel and the flavor of accompanying B meson is
identified from itsdecay products. From the asymmetry in the distribution of
the time intervals between the two B meson decay points, we obtain sin2phi_1 =
0.719 +/- 0.074(stat) +/- 0.035(syst). We also report measurements of CP
violation parameters for the related B^0 -> J/psi pi^0 decay mode and the
penguin-dominated processes B^0 -> eta' K_S, phi K_S and K^+K^- K_S.Comment: 11 pages, 4 figures, 4 tables, contributed to ICHEP200
A partial wave analysis of the system produced in charge exchange collisions
A partial wave analysis of the of the system produced in the
charge exchange reaction: at an incident momentum of
is presented as a function of invariant mass,
, and momentum transfer squared, , from the incident
to the outgoing system.Comment: 24 pages total,8 pages text, 14 figures, 1 table. Submitted to Phys
Rev
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