17,974 research outputs found

    Apollo gastrointestinal analysis

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    Fecal bile acid patterns for the Apollo 17 flight were studied to determine the cause of diarrhea on the mission. The fecal sterol analysis gave no indication of an infectious diarrhea, or specific, or nonspecific etiology occurring during the entire flight. It is assumed that the gastrointestinal problems encountered are the consequences of altered physiology, perhaps secondary to physical or emotional stress of flight

    Method and apparatus for fabricating improved solar cell modules

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    A method and apparatus for fabricating an improved solar cell module is described. The apparatus includes a supply drum for feeding a flexible strip having etched electrical circuitry deposited on it a supply drum for feeding into overlying engagement with the flexible strip a flexible tape having a pair of exposed tacky surfaces, and a plurality of rams for receiving and depositing a plurality of solar cells in side-by-side relation on an exposed tacky surface of the tape in electrical contacting engagement with the etched circuitry

    Investigation of fast initialization of spacecraft bubble memory systems

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    Bubble domain technology offers significant improvement in reliability and functionality for spacecraft onboard memory applications. In considering potential memory systems organizations, minimization of power in high capacity bubble memory systems necessitates the activation of only the desired portions of the memory. In power strobing arbitrary memory segments, a capability of fast turn on is required. Bubble device architectures, which provide redundant loop coding in the bubble devices, limit the initialization speed. Alternate initialization techniques are investigated to overcome this design limitation. An initialization technique using a small amount of external storage is demonstrated

    Supporting the active learning of collaborative database browsing techniques

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    We describe the implications of a study of database browsing behaviour for the development of a system to support more effective browsing. In particular we consider the importance of collaborative working, both in learning browsing skills and in co‐operating on a shared information‐retrieval task. From our study, we believe that an interface to support collaboration should promote the awareness of the activities of others, better visualization of the information data structures being browsed, and effective communication of the browsing process

    GLM permutation - nonparametric inference for arbitrary general linear models

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    Introduction: Permutation methods are finding growing use in neuroimag- ing data analyses (e.g. randomise in FSL, SnPM in SPM, XBAMM/BAMM/CAMBA, etc). These methods provide ex- act control of false positives, make only weak assumptions, and allow nonstandard types of statistics (e.g. smoothed variance t- test). With fast and inexpensive computing, there would seem few reasons not to use nonparametric methods. A significant limitation of these methods, however, is the lack of flexibility with respect to the experimental design and nuisance variables. Each specific design dictates the type of exchange- ability of null data, and hence how to permute. Nuisance effects (e.g. age) render data non-exchangeable even when the effect of interest is null. Hence, even something as simple as ANCOVA has no exact permutation test. Recently there has been an active literature on approximate– but accurate–permutation tests for 2-variable regression, one effect of interest, one nuisance (see review by Anderson & Robinson [1]). Here we extend and evaluate these methods for use with an arbitrary General Linear Model (GLM)

    Completion Report: Arkansas State Pesticides in Ground Water Monitoring Project Phase V: Vulnerable areas in Jackson, Monroe, Lawrence and Lonoke Counties

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    In 1996, sixty-seven water samples were drawn from 65 wells, including 62 new wells and 3 wells sampled previously . One Woodruff County well and two Pulaski County wells were resampled. Thirty-two samples were drawn from 30 wells in Monroe County (well #1 was sampled 3 times during this phase) . Ten wells in Jackson County, 12 wells in Lawrence County and 10 wells in Lonoke were also tested (Figures 1-5) . With the completion of Phase V, the number of wells tested has risen to 231 with a total of 258 samples analyzed . Initially, the wells were tested for 13 pesticides and ni~rate. Two more pesticides, aldicarb and carbofuran were added to the analyte list during Phase V. The analyte list is shown in Table 3 . All results from all the wells are listed in Appendix A. Quality control information for these data follow the results. The Phase V Quality Assurance Report is included in this document as Part II

    Longitudinal multivariate tensor- and searchlight-based morphometry using permutation testing

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    Tensor based morphometry [1] was used to detect statistically significant regions of neuroanatomical change over time in a comparison between 36 probable Alzheimer's Disease patients and 20 age- and sexmatched controls. Baseline and twelve-month repeat Magnetic Resonance images underwent tied spatial normalisation [10] and longitudinal high-dimensional warps were then estimated. Analyses involved univariate and multivariate data derived from the longitudinal deformation fields. The most prominent findings were expansion of the fluid spaces, and contraction of the hippocampus and temporal region. Multivariate measures were notably more powerful, and have the potential to identify patterns of morphometric difference that would be overlooked by conventional mass-univariate analysis

    Distributed Queries for Quality Control Checks in Clinical Trials

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    Operational Quality Control (QC) checks are standard practice in clinical trials and ensure ongoing compliance with the study protocol, standard operating procedures (SOPs) and Good Clinical Practice (GCP). We present a method for defining QC checks as distributed queries over case report forms (CRF) and clinical imaging data- sources. Our distributed query system can integrate time-sensitive information in order to populate QC checks that can facilitate discrepancy resolution workflow in clinical trials
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