309 research outputs found
Einstein metrics in projective geometry
It is well known that pseudo-Riemannian metrics in the projective class of a
given torsion free affine connection can be obtained from (and are equivalent
to) the solutions of a certain overdetermined projectively invariant
differential equation. This equation is a special case of a so-called first BGG
equation. The general theory of such equations singles out a subclass of
so-called normal solutions. We prove that non-degerate normal solutions are
equivalent to pseudo-Riemannian Einstein metrics in the projective class and
observe that this connects to natural projective extensions of the Einstein
condition.Comment: 10 pages. Adapted to published version. In addition corrected a minor
sign erro
Inhibition of CYP2D6 with low dose (5 mg) paroxetine in patients with high 10-hydroxynortriptyline serum levels-A prospective pharmacokinetic study
The antidepressant nortriptyline is metabolized by cytochrome P450 2D6 (CYP2D6) to the less active and more cardiotoxic drug metabolite, 10-hydroxynortriptyline. High serum levels of this metabolite (>200 μg/L) may lead to withdrawal of nortriptyline therapy. Adding CYP2D6 inhibitors reduce the metabolic activity of CYP2D6 (phenoconversion) and so decrease the forming of hydroxynortriptyline. In this study, 5 mg paroxetine is administered to patients with high hydroxynortriptyline concentrations (>200 μg/L). The shift in number of patients to therapeutic nortriptyline (50-150 μg/L) and safe hydroxynortriptyline (<200 μg/L) concentrations, and the degree of phenoconversion, expressed as the change in ratio nortriptyline/hydroxynortriptyline concentrations before and after paroxetine addition, are prospectively observed and described. After paroxetine addition, 12 patients (80%) had therapeutic nortriptyline and safe hydroxynortriptyline concentrations. Hydroxynortriptyline concentrations decreased in all patients. The average nortriptyline/hydroxynortriptyline concentrations ratio increased from 0.32 to 0.59. This study shows that 5 mg paroxetine addition is able to lower high hydroxynortriptyline serum levels to safe ranges
Emerging IT risks: insights from German banking
How do German banks manage the emerging risks stemming from IT innovations such as cyber risk? With a focus on process, roles and responsibilities, field data from ten banks participating in the 2014 ECB stress test were collected by interviewing IT managers, risk managers and external experts. Current procedures for handling emerging risks in German banks were identified from the interviews and analysed, guided by the extant literature. A clear gap was found between enterprise risk management (ERM) as a general approach to risks threatening firms’ objectives and ERM’s neglect of emerging risks, such as those associated with IT innovations. The findings suggest that ERM should be extended towards the collection and sharing of knowledge to allow for an initial understanding and description of emerging risks, as opposed to the traditional ERM approach involving estimates of impact and probability. For example, as cyber risks emerge from an IT innovation, the focus may need to switch towards reducing uncertainty through knowledge acquisition. Since individual managers seldom possess all relevant knowledge of an IT innovation, various stakeholders may need to be involved to exploit their expertise
Transverse momentum and centrality dependence of dihadron correlations in Au+Au collisions at sqrt(s_NN)=200 GeV: Jet-quenching and the response of partonic matter
Azimuthal angle \Delta\phi correlations are presented for charged hadrons
from dijets for 0.4 < p_T < 10 GeV/c in Au+Au collisions at sqrt(s_NN) = 200
GeV. With increasing p_T, the away-side distribution evolves from a broad to a
concave shape, then to a convex shape. Comparisons to p+p data suggest that the
away-side can be divided into a partially suppressed "head" region centered at
Delta\phi ~ \pi, and an enhanced "shoulder" region centered at Delta\phi ~ \pi
+/- 1.1. The p_T spectrum for the "head" region softens toward central
collisions, consistent with the onset of jet quenching. The spectral slope for
the "shoulder" region is independent of centrality and trigger p_T, which
offers constraints on energy transport mechanisms and suggests that the
"shoulder" region contains the medium response to energetic jets.Comment: 420 authors from 58 institutions, 6 pages, 4 figures. Submitted to
Physical Review Letters. Plain text data tables for the points plotted in
figures for this and previous PHENIX publications are (or will be) publicly
available at http://www.phenix.bnl.gov/papers.htm
Cold Nuclear Matter Effects on J/psi Yields as a Function of Rapidity and Nuclear Geometry in Deuteron-Gold Collisions at sqrt(s_NN) = 200 GeV
We present measurements of J/psi yields in d+Au collisions at sqrt(s_NN) =
200 GeV recorded by the PHENIX experiment and compare with yields in p+p
collisions at the same energy per nucleon-nucleon collision. The measurements
cover a large kinematic range in J/psi rapidity (-2.2 < y < 2.4) with high
statistical precision and are compared with two theoretical models: one with
nuclear shadowing combined with final state breakup and one with coherent gluon
saturation effects. To remove model dependent systematic uncertainties we also
compare the data to a simple geometric model. We find that calculations where
the nuclear modification is linear or exponential in the density weighted
longitudinal thickness are difficult to reconcile with the forward rapidity
data.Comment: 449 authors from 66 institutions, 6 pages, 3 figures. Submitted to
Physical Review Letters. Plain text data tables for the points plotted in
figures for this and previous PHENIX publications are (or will be) publicly
available at http://www.phenix.bnl.gov/papers.htm
Transverse momentum dependence of J/psi polarization at midrapidity in p+p collisions at sqrt(s)=200 GeV
We report the measurement of the transverse momentum dependence of inclusive
J/psi polarization in p+p collisions at sqrt(s)=200 GeV performed by the PHENIX
Experiment at RHIC. The polarization is studied in the helicity,
Gottfried-Jackson, and Collins-Soper frames for p_T < 5 GeV/c and |y| < 0.35.
The J/psi polarization in the helicity and Gottfried-Jackson frames is
consistent with zero for all transverse momenta, with a slight (1.8 sigma)
trend towards longitudinal polarization for transverse momenta above 2 GeV/c.
No conclusion is allowed due to the limited acceptance in the Collins-Soper
frame and the uncertainties of the current data. The results are compared to
observations for other collision systems and center of mass energies and to
different quarkonia production models.Comment: 384 authors from 62 institutions, 11 pages, 9 figures, 2 tables. v2
is expanded version submitted to Physical Review D. Plain text data tables
for the points plotted in figures are available at
http://www.phenix.bnl.gov/papers.htm
Azimuthal anisotropy of neutral pion production in Au+Au collisions at sqrt(s_NN) = 200 GeV: Path-length dependence of jet quenching and the role of initial geometry
We have measured the azimuthal anisotropy of pi0's for 1 < pT < 18 GeV/c for
Au+Au collisions at sqrt s_NN = 200 GeV. The observed anisotropy shows a
gradual decrease in 3 < pT < 7 - 10 GeV/c, but remains positive beyond 10
GeV/c. The magnitude of this anisotropy is under-predicted, up to at least 10
GeV/c, by current perturbative QCD (pQCD) energy-loss model calculations. An
estimate of the increase in anisotropy expected from initial-geometry
modification due to gluon saturation effects and initial-geometry fluctuations
is insufficient to account for this discrepancy. Calculations which implement a
path length dependence steeper than what is implied by current pQCD energy-loss
models, show reasonable agreement with the data.Comment: 384 authors, 6 pages text, 3 figures. Submitted to Phys. Rev. Lett.
Plain text data tables for the points plotted in figures for this and
previous PHENIX publications are (or will be) publicly available at
http://www.phenix.bnl.gov/papers.htm
Cold Nuclear Matter Effects on J/Psi as Constrained by Deuteron-Gold Measurements at sqrt(s_NN) = 200 GeV
We present a new analysis of J/psi production yields in deuteron-gold
collisions at sqrt(s_NN) = 200 GeV using data taken by the PHENIX experiment in
2003 and previously published in [S.S. Adler et al., Phys. Rev. Lett 96, 012304
(2006)]. The high statistics proton-proton J/psi data taken in 2005 is used to
improve the baseline measurement and thus construct updated cold nuclear matter
modification factors R_dAu. A suppression of J/psi in cold nuclear matter is
observed as one goes forward in rapidity (in the deuteron-going direction),
corresponding to a region more sensitive to initial state low-x gluons in the
gold nucleus. The measured nuclear modification factors are compared to
theoretical calculations of nuclear shadowing to which a J/psi (or precursor)
break-up cross-section is added. Breakup cross sections of sigma_breakup =
2.8^[+1.7_-1.4] (2.2^[+1.6_-1.5]) mb are obtained by fitting these calculations
to the data using two different models of nuclear shadowing. These breakup
cross section values are consistent within large uncertainties with the 4.2 +/-
0.5 mb determined at lower collision energies. Projecting this range of cold
nuclear matter effects to copper-copper and gold-gold collisions reveals that
the current constraints are not sufficient to firmly quantify the additional
hot nuclear matter effect.Comment: 453 authors from 59 institutions, 15 pages, 13 figures, 5 tables.
Submitted to Physical Review C. Plain text data tables for the points plotted
in figures for this and previous PHENIX publications are (or will be)
publicly available at http://www.phenix.bnl.gov/papers.htm
High p_T Direct Photon and pi^0 Triggered Azimuthal Jet Correlations in sqrt(s)=200 GeV p+p Collisions
Correlations of charged hadrons of 1 < pT < 10 GeV/c with high pT direct
photons and pi^ 0 mesons in the range 5 <pT < 15 GeV/c are used to study jet
fragmentation in the photon+jet and di-jet channels, respectively. The
magnitude of the partonic transverse momentum, kT, is obtained by comparing to
a model incorporating a Gaussian kT smearing. The sensitivity of the associated
charged hadron spectra to the underlying fragmentation function is tested and
the data are compared to calculations using recent global fit results. The
shape of the direct photon-associated hadron spectrum as well as its charge
asymmetry are found to be consistent with a sample dominated by quark-gluon
Compton scattering. No significant evidence of fragmentation photon correlated
production is observed within experimental uncertainties.Comment: 431 authors, 18 pages, 18 figures, 4 tables, RevTeX-4. Submitted to
Physical Review D. Plain text data tables for the points plotted in figures
for this and previous PHENIX publications are (or will be) publicly available
at http://www.phenix.bnl.gov/papers.htm
Inclusive cross section and double helicity asymmetry for \pi^0 production in p+p collisions at sqrt(s)=200 GeV: Implications for the polarized gluon distribution in the proton
The PHENIX experiment presents results from the RHIC 2005 run with polarized
proton collisions at sqrt(s)=200 GeV, for inclusive \pi^0 production at
mid-rapidity. Unpolarized cross section results are given for transverse
momenta p_T=0.5 to 20 GeV/c, extending the range of published data to both
lower and higher p_T. The cross section is described well for p_T < 1 GeV/c by
an exponential in p_T, and, for p_T > 2 GeV/c, by perturbative QCD. Double
helicity asymmetries A_LL are presented based on a factor of five improvement
in uncertainties as compared to previously published results, due to both an
improved beam polarization of 50%, and to higher integrated luminosity. These
measurements are sensitive to the gluon polarization in the proton, and exclude
maximal values for the gluon polarization.Comment: 375 authors, 7 pages, 3 figures. Submitted to Phys. Rev. D, Rapid
Communications. Plain text data tables for the points plotted in figures for
this and previous PHENIX publications are (or will be) publicly available at
http://www.phenix.bnl.gov/papers.htm
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