Silent and Oral Reading Comprehension Abilities of Second Grade Students Completing the Second S.T.E.P. Program

This study focused on the silent and oral reading abilities of second grade students completing the Second S.T.E.P. Program. There were approximately seven second-grade students that participated. All 7 of the students are presently attending an elementary school located in western New York. The research questions concentrated on were: 1. Is there a statistically significant difference between the mean score of the pretest and the mean score of the posttest for unprompted memory, unprepared reading? 2. Is there a statistically significant difference between the mean score of the pretest and the mean score of the posttest for prompted memory, unprepared reading? 3. Is there a statistically significant difference between the mean score of the pretest and the mean score of the posttest for unprompted memory, prepared reading? 4. Is there a statistically significant difference between the mean score of the pretest and the mean score of the posttest for prompted memory, prepared reading? Each of the seven participants was administered in a one-on-one setting a pretest and a posttest version of the Bader Reading and Language Inventory in a 30-40 minute period. The pretest and the posttest each contained four sets of scores: unprompted memory (retelling), prompted memory (cued recall) after a unprepared (silent) reading and unprompted memory (retelling), prompted memory (cued recall) after a prepared (silent /oral) reading. The data were tallied and categorized into four sets of scores. Each set of scores was calculated utilizing a t-test of dependent means. The results of the t-test of dependent means indicated that there was no statistically significant difference between the mean pretest and mean posttest scores for all four sets of scores

The carbon dioxide removal potential of Liquid Air Energy Storage: A high-level technical and economic appraisal

Liquid Air Energy Storage (LAES) is at pilot scale. Air cooling and liquefaction stores energy; reheating revaporises the air at pressure, powering a turbine or engine (Ameel et al., 2013). Liquefaction requires water & CO2 removal, preventing ice fouling. This paper proposes subsequent geological storage of this CO2 - offering a novel Carbon Dioxide Removal (CDR) by-product, for the energy storage industry. It additionally assesses the scale constraint and economic opportunity offered by imple- menting this CDR approach. Similarly, established Com- pressed Air Energy Storage (CAES) uses air compression and subsequent expansion. CAES could also add CO2scrubbing and subsequent storage, at extra cost. CAES stores fewer joules per kilogram of air than LAES - potentially scrubbing more CO2 per joule stored. Opera- tional LAES/CAES technologies cannot offer full-scale CDR this century (Stocker et al., 2014), yet they could offer around 4% of projected CO2 disposals for LAES and < 25% for current-technology CAES. LAES CDR could reach trillion-dollar scale this century (20 billion USD/year, to first order). A larger, less certain commercial CDR opportunity exists for modified conventional CAES, due to additional equipment requirements. CDR may be commercially critical for LAES/CAES usage growth, and the necessary infrastructure may influence plant scaling and placement. A suggested design for low-pressure CAES theoretically offers global-scale CDR potential within a century (ignoring siting constraints) - but this must be costed against competing CDR and energy storage technologies

Hominin tracks in southern Africa: a review and an approach to identification

Three Late Pleistocene hominin tracksites have been reported from coastal aelioanites in South Africa. Two have been dated to 124 ka and 117 ka , and the third is inferred to be 90 ka. There are no other globally reported sites for probable Homo sapiens tracks older than 46 ka. Given this documented record, a search for further hominin tracksites in southern Africa may well yield additional positive results. However, this is a field that demands scientific rigour, as false positive tracksites (pseudotracks) may occur. Criteria have been developed for the identification of fossil vertebrate tracks and hominin tracks, but these are specific neither to southern Africa nor to aeolianites.An important caveat is that the tracks of shod humans would not fulfil these criteria. Preservation of tracks varies with facies and is known to be suboptimal in aeolianites. An analysis of the tracks from the three documented South African sites, along with pseudotracks and tracks of questionable provenance, allows for the proposal and development of guidelines for fossil hominin track identification that are of specific relevance to southern Africa. Such guidelines have broader implications for understanding the constraints that track preservation and substrate have on identifying diagnostic morphological features.Palaeontological Scientific Trust (PAST)JNC201

Sleep and recovery in physicians on night call: a longitudinal field study

<p>Abstract</p> <p>Background</p> <p>It is well known that physicians' night-call duty may cause impaired performance and adverse effects on subjective health, but there is limited knowledge about effects on sleep duration and recovery time. In recent years occupational stress and impaired well-being among anaesthesiologists have been frequently reported for in the scientific literature. Given their main focus on handling patients with life-threatening conditions, when on call, one might expect sleep and recovery to be negatively affected by work, especially in this specialist group. The aim of the present study was to examine whether a 16-hour night-call schedule allowed for sufficient recovery in anaesthesiologists compared with other physician specialists handling less life-threatening conditions, when on call.</p> <p>Methods</p> <p>Sleep, monitored by actigraphy and Karolinska Sleep Diary/Sleepiness Scale on one night after daytime work, one night call, the following first and second nights post-call, and a Saturday night, was compared between 15 anaesthesiologists and 17 paediatricians and ear, nose, and throat surgeons.</p> <p>Results</p> <p>Recovery patterns over the days after night call did not differ between groups, but between days. Mean night sleep for all physicians was 3 hours when on call, 7 h both nights post-call and Saturday, and 6 h after daytime work (p < 0.001). Scores for mental fatigue and feeling well rested were poorer post-call, but returned to Sunday morning levels after two nights' sleep.</p> <p>Conclusions</p> <p>Despite considerable sleep loss during work on night call, and unexpectedly short sleep after ordinary day work, the physicians' self-reports indicate full recovery after two nights' sleep. We conclude that these 16-hour night duties were compatible with a short-term recovery in both physician groups, but the limited sleep duration in general still implies a long-term health concern. These results may contribute to the establishment of safe working hours for night-call duty in physicians and other health-care workers.</p

Mainstreamed Genetic Testing in Ovarian Cancer: Patient Experience of the Testing Process

Objective: Pathogenic BRCA variants account for between 5.8-24.8% of ovarian cancers. The identification of such a variant can have a significant impact on the affected individual and their relatives – determining eligibility for targeted therapies, predicting treatment response and granting access to disease prevention strategies. Cancer services are responding to the increased demand for genetic testing with the introduction of mainstreamed genetic testing via oncology clinics. The study aimed to evaluate patient experience of the mainstreamed genetic testing pathway at a tertiary referral centre in London. / Methods: Study participants were patients diagnosed with high-grade non-mucinous ovarian cancer, tested via a mainstreamed genetic testing pathway at the tertiary referral centre between February 2015 and June 2017. Eligible participants were invited to complete the retrospective study questionnaire. Five quantitative measures with additional free-text items evaluated the patient experience of mainstreamed genetic testing. / Results: The tertiary referral centre tested 170 ovarian cancer patients. Twenty-three pathogenic BRCA mutations were identified (23/170, 13.5%). One-hundred and six patients (106/170, 62.4%) met the study inclusion criteria. Twenty-nine of those invited (29/106, 27.4%) to participate returned the retrospective study questionnaire. Pathogenic BRCA1/2 variants were identified within four respondents (4/29, 13.8%). Motivations for genetic testing related to improved medical management, and the ability to provide relatives with genetic information. Participants did not appear to be adversely affected by result disclosure post mainstreamed genetic testing. Two individuals with a pathogenic variant reported that the support provided by the tertiary referral centre post-result disclosure could have been improved. / Conclusion: Results of the current study support further psychosocial research into the expansion of the mainstreamed genetic testing pathway. The results although promising have also highlighted the importance of genetic awareness within the multidisciplinary team and the provision of timely psychological support from genetic specialists

Late Pleistocene vertebrate trace fossils in the Goukamma Nature Reserve, Cape South Coast, South Africa

More than 100 Late Pleistocene trace fossil sites have been identified in aeolianites along a 275 kilometer stretch of the Cape south coast. A zone of concentration of such sites exists within the Goukamma Nature Reserve, both along the coast and along the Goukamma River. These sites provide insight into the Pleistocene fauna along the Cape south coast. Features include lion trackways, multiple elephant tracksites, a long trackway most likely attributable to Long-horned Buffalo, medium-sized carnivore tracks, avian tracks, equid tracks attributable to the giant Cape horse, numerous artiodactyl tracks, and burrow traces. The ephemeral nature of the tracksites makes regular surveys of these areas desirable, along with site documentation and trackway replication and preservation initiatives. The protected status of the area offers opportunities for geoheritage appreciation.JN

Neither bones nor feet: track morphological variation and “preservation quality”

As purely sedimentary structures, fossil footprints are all about shape. Correctly interpreting the significance of their surface topography requires understanding the sources of morphological variation. Differences among specimens are most frequently attributed to either taxonomy (trackmaker) or to preservation quality. “Well-preserved” tracks are judged more similar to pedal anatomy than “poorly preserved” ones, but such broad-brush characterizations confound two separate episodes in a track’s history. Current evaluations of track quality fail to distinguish among behavioral, formational, intravolumetric, and post-formational sources of variation. Based on analogy with body fossils, we recommend restricting assessments of track preservation quality to modifications that take place only after a track is created. Ichnologists need to try to parse the relative influence of factors affecting disparity, but we currently lack an adequate vocabulary to describe the overall shapes and specific features of formational variants

Meeting Report: The Role of Environmental Lighting and Circadian Disruption in Cancer and Other Diseases

Light, including artificial light, has a range of effects on human physiology and behavior and can therefore alter human physiology when inappropriately timed. One example of potential light-induced disruption is the effect of light on circadian organization, including the production of several hormone rhythms. Changes in light–dark exposure (e.g., by nonday occupation or transmeridian travel) shift the timing of the circadian system such that internal rhythms can become desynchronized from both the external environment and internally with each other, impairing our ability to sleep and wake at the appropriate times and compromising physiologic and metabolic processes. Light can also have direct acute effects on neuroendocrine systems, for example, in suppressing melatonin synthesis or elevating cortisol production that may have untoward long-term consequences. For these reasons, the National Institute of Environmental Health Sciences convened a workshop of a diverse group of scientists to consider how best to conduct research on possible connections between lighting and health. According to the participants in the workshop, there are three broad areas of research effort that need to be addressed. First are the basic biophysical and molecular genetic mechanisms for phototransduction for circadian, neuroendocrine, and neurobehavioral regulation. Second are the possible physiologic consequences of disrupting these circadian regulatory processes such as on hormone production, particularly melatonin, and normal and neoplastic tissue growth dynamics. Third are effects of light-induced physiologic disruption on disease occurrence and prognosis, and how prevention and treatment could be improved by application of this knowledge

Circadian-Related Sleep Disorders and Sleep Medication Use in the New Zealand Blind Population: An Observational Prevalence Survey

STUDY OBJECTIVES: To determine the prevalence of self-reported circadian-related sleep disorders, sleep medication and melatonin use in the New Zealand blind population. DESIGN: A telephone survey incorporating 62 questions on sleep habits and medication together with validated questionnaires on sleep quality, chronotype and seasonality. PARTICIPANTS: PARTICIPANTS WERE GROUPED INTO: (i) 157 with reduced conscious perception of light (RLP); (ii) 156 visually impaired with no reduction in light perception (LP) matched for age, sex and socioeconomic status, and (iii) 156 matched fully-sighted controls (FS). SLEEP HABITS AND DISTURBANCES: The incidence of sleep disorders, daytime somnolence, insomnia and sleep timing problems was significantly higher in RLP and LP compared to the FS controls (p<0.001). The RLP group had the highest incidence (55%) of sleep timing problems, and 26% showed drifting sleep patterns (vs. 4% FS). Odds ratios for unconventional sleep timing were 2.41 (RLP) and 1.63 (LP) compared to FS controls. For drifting sleep patterns, they were 7.3 (RLP) and 6.0 (LP). MEDICATION USE: Zopiclone was the most frequently prescribed sleep medication. Melatonin was used by only 4% in the RLP group and 2% in the LP group. CONCLUSIONS: Extrapolations from the current study suggest that 3,000 blind and visually impaired New Zealanders may suffer from circadian-related sleep problems, and that of these, fewer than 15% have been prescribed melatonin. This may represent a therapeutic gap in the treatment of circadian-related sleep disorders in New Zealand, findings that may generalize to other countries

Ocular measures of sleepiness are increased in night shift workers undergoing a simulated night shift near the peak time of the 6-sulfatoxymelatonin rhythm

Study Objectives: The study examined the relationship between the circadian rhythm of 6-sulphatoxymelatonin (aMT6s) and ocular measures of sleepiness and neurobehavioral performance in shift workers undergoing a simulated night shift. Methods: Twenty-two shift workers (mean age 33.4, SD 11.8 years) were tested at approximately the beginning (20:00) and the end (05:55) of a simulated night shift in the laboratory. At the time point corresponding to the end of the simulated shift, 14 participants were classified as being within range of 6-sulphatoxymelatonin (aMT6s) acrophase— defined as 3 hours before or after aMT6s peak—and 8 were classified as outside aMT6s acrophase range. Participants completed the Karolinska Sleepiness Scale (KSS) and the auditory psychomotor vigilance task (aPVT). Waking electroencephalography (EEG) was recorded and infrared reflectance oculography was used to collect ocular measures of sleepiness: positive and negative amplitude/velocity ratio (PosAVR, NegAVR), mean blink total duration (BTD), the percentage of eye closure (%TEC), and a composite score of sleepiness levels (Johns Drowsiness Scale; JDS). Results: Participants who were tested within aMT6s acrophase range displayed higher levels of sleepiness on ocular measures (%TEC, BTD, PosAVR, JDS), objective sleepiness (EEG delta power frequency band), subjective ratings of sleepiness, and neurobehavioral performance, compared to those who were outside aMT6s acrophase range. Conclusions: The study demonstrated that objective ocular measures of sleepiness are sensitive to circadian rhythm misalignment in shift workers. Citation: Ftouni S, Sletten TL, Nicholas CL, Kennaway DJ, Lockley SW, Rajaratnam SM. Ocular measures of sleepiness are increased in night shift workers undergoing a simulated night shift near the peak time of the 6-sulfatoxymelatonin rhythm. J Clin Sleep Med 2015;11(10):1131–1141.Suzanne Ftouni, Tracey L. Sletten, Christian L. Nicholas, David J. Kennaway, Steven W. Lockley, Shantha M.W. Rajaratna