Galactic exploration by directed Self-Replicating Probes, and its implications for the Fermi paradox

This paper proposes a long term scheme for robotic exploration of the galaxy,and then considers the implications in terms of the `Fermi paradox' and our search for ETI. We discuss the parameter space of the `galactic ecology' of civilizations in terms of the parameters T (time between ET civilizations arising) and L, the lifetime of these civilizations. Six different regions are described.Comment: 1 figur

Development of improved heat sterilizable potting compounds third quarterly report, 1 jan. - 31 mar. 1964

Development of heat sterilizable potting compoun

Ecological Observations on Predatory Coccinellidae (Coleoptera) in Southwestern Michigan

Ecological observations on habitat utilization by thirteen species of predatory Coccinellidae were made at a southern Michigan site during 1989 and 1990. Most of species were common during both years and used both agricul- tural and uncultivated habitats. Coccinella septempunctata and Coleomegilla maculata, were the most abundant in agricultural crops (alfalfa, maize, soy- bean and triticale), whereas Adalia bipunctata and Cycloneda munda, were the most abundant in deciduous and bushy habitats

From amaurosis fugax to asymptomatic bithalamic infarct

Bilateral paramedian thalamic infarctions are usually associated with impaired consciousness, oculomotor disturbances and neuropsychological changes. A 44-year-old healthy woman presented with amaurosis fugax of the right eye immediately after a Valsalva maneuver. Neurological examination, in particular visual acuity, vigilance and ocular movements, was normal. Blood pressure, ECG and angio-CT of the neck and head vessels were normal, but MRI/DWI and T2 sequences showed recent bi-thalamic ischemic lesions in the paramedian territories. Doppler sonography and transesophageal echocardiography showed a large right-to-left shunt due to an atrial communication, with septum aneurysm. Twenty-four-hours cardiac monitoring was normal but prior to an eventual closure of the cardiac defect she underwent an ambulatory 7-day ECG monitoring which revealed several paroxystic short lasting passages into atrial fibrillation, unnoticed by the patient. The interest in this case is threefold: (1) bilateral paramedian thalamic infarction which usually presents with a devastating clinical picture may occur clinically silent; (2) monocular amaurosis fugax which is usually associated with ipsilateral carotid disease may be the consequence of cardiac embolism, and (3) atrial fibrillation is never completely ruled out, here it was caught only in a 7-days ambulatory R-test, and consequently prevented closure of a possibly asymptomatic patent foramen oval

Survey of users of earth resources remote sensing data

A user survey was conducted to determine current earth resources survey (ERS) data use/user status and recommendations for strengthening use. Only high-altitude aircraft and satellite (primarily LANDSAT) data were included. Emphasis was placed on the private sector/industrial user. Objectives of the survey included: who is using ERS data, how they are using the data, the relative value of current data use as well as obtaining user views as to possible ways of strengthening future ERS data use. The survey results are documented and should provide relevant decision making information for developing future programs of maximum benefit to all end users of satellite ERS data

DNA methylation-based age prediction and telomere length in white blood cells and cumulus cells of infertile women with normal or poor response to ovarian stimulation.

An algorithm assessing the methylation levels of 353 informative CpG sites in the human genome permits accurate prediction of the chronologic age of a subject. Interestingly, when there is discrepancy between the predicted age and chronologic age (age acceleration or AgeAccel ), patients are at risk for morbidity and mortality. Identification of infertile patients at risk for accelerated reproductive senescence may permit preventative action. This study aimed to assess the accuracy of the epigenetic clock concept in reproductive age women undergoing fertility treatment by applying the age prediction algorithm in peripheral (white blood cells [WBCs]) and follicular somatic cells (cumulus cells [CCs]), and to identify whether women with premature reproductive aging (diminished ovarian reserve) were at risk of AgeAccel in their age prediction. Results indicated that the epigenetic algorithm accurately predicts age when applied to WBCs but not to CCs. The age prediction of CCs was substantially younger than chronologic age regardless of the patient\u27s age or response to stimulation. In addition, telomeres of CCs were significantly longer than that of WBCs. Our findings suggest that CCs do not demonstrate changes in methylome-predicted age or telomere-length in association with increasing female age or ovarian response to stimulation

Gold Standard Online Debates Summaries and First Experiments Towards Automatic Summarization of Online Debate Data

Usage of online textual media is steadily increasing. Daily, more and more news stories, blog posts and scientific articles are added to the online volumes. These are all freely accessible and have been employed extensively in multiple research areas, e.g. automatic text summarization, information retrieval, information extraction, etc. Meanwhile, online debate forums have recently become popular, but have remained largely unexplored. For this reason, there are no sufficient resources of annotated debate data available for conducting research in this genre. In this paper, we collected and annotated debate data for an automatic summarization task. Similar to extractive gold standard summary generation our data contains sentences worthy to include into a summary. Five human annotators performed this task. Inter-annotator agreement, based on semantic similarity, is 36% for Cohen's kappa and 48% for Krippendorff's alpha. Moreover, we also implement an extractive summarization system for online debates and discuss prominent features for the task of summarizing online debate data automatically.Comment: accepted and presented at the CICLING 2017 - 18th International Conference on Intelligent Text Processing and Computational Linguistic

NASA Innovative Advanced Concepts (NIAC) Phase 1 Final Report: Venus Landsailer Zephyr

Imagine sailing across the hot plains of Venus! A design for a craft to do just this was completed by the COncurrent Multidisciplinary Preliminary Assessment of Space Systems (COMPASS) Team for the NASA Innovative Advanced Concepts (NIAC) project. The robotic craft could explore over 30 km of surface of Venus, driven by the power of the wind