373 research outputs found
UJI AKTIVITAS ANTIFUNGAL MINYAK ATSIRI BUAH PALA (MYRISTICA FRAGRANS HOUTT) TERHADAP JAMUR CANDIDA ALBICANS SECARA IN VITRO
Peranan Hukum Adat dalam Menjaga Kelestarian Hutan Larangan Adat Kenegerian Rumbio Kecamatan Kampar Kabupaten Kampar
One example of common law in Indonesia is common law in Kenegerian Rumbio, Kampar District, Kampar Regency, Riau Province. Kenegerian Rumbio has banned indigenous forest still maintained continuity. The forest area is listed on the Forest department is approximately 530 ha. This is research used a snowball sampling technique, subjects were selected based on recommendations person to person according to research to be interviewed. Data collection methods used in this study were in-depth interviews, observation, and study documents. The data analysis was conducted in three phases. The first phase, researchers conducted an analysis that linked the answers intrasubjek subjects with theory and concepts related to the research. The second phase, conducted antarsubjek analysis comparing data from each subject. At this stage, researchers performed the interpretation of the data so as to achieve the purpose of research. The third phase, the data collected were then analyzed using descriptive analysis. Kenegerian Rumbio customary law has two forms of customary rules in the forest preserve customary prohibition, namely: the rules of the ban and the rules of thing is allowed. The rules of prohibition are: cutting down trees without permission from the ninik mamak, burn the forest, enable divert forest land, wildlife hunting, arrogant when entering the forest, and speaking dirty in the woods. While the form of the permitted rules are: take firewood (wood that is already dead), took the fruit has matured, and conduct scientific research. If there is a breach in the case, the perpetrator will be prosecuted according to the customary laws in Kenegerian Rumbio. The perpetrator will be given sanction in accordance with the agreement of the ninik mamak in the deliberations conducted in the customary hall
Analisis Modal Sosial Kelompok USAha Agroindustri Keripik Nenas di Desa Kualu Nenas Kecamatan Tambang Kabupaten Kampar
This research aims to determine the social capital in the bussiness group of pineapple chips agro-industry. This research uses a survey method with respondents consist of 12 craftsman pineapple chips. Data collection method in this research is primary data and secondary data. To determine the social capital in this research using a quantitative method using a questionnaire in the form of Likert Scale. Social capital in this research in view of the three elements of the network, social norms and trush. Value of the network of their way association, social norms in the value of the formation of attitudes and regulatory compliance, value of trush from the trush they have to offer a contribution to the bussiness group of pineapple chips agro-industry. Social capital in the of pineapple chips scored 3.24 are categorized high enough
Expansionfree Fluid Evolution and Skripkin Model in f(R) Theory
We consider the modified theory of gravity whose higher order
curvature terms are interpreted as a gravitational fluid or dark source. The
gravitational collapse of a spherically symmetric star, made up of locally
anisotropic viscous fluid, is studied under the general influence of the
curvature fluid. Dynamical equations and junction conditions are modified in
the context of f(R) dark energy and by taking into account the expansionfree
evolution of the self-gravitating fluid. As a particular example, the Skripkin
model is investigated which corresponds to isotropic pressure with constant
energy density. The results are compared with corresponding results in General
Relativity.Comment: 18 pages, accepted for publication Int. J. Mod. Phys.
Gender: shaping personality, lives and health of women in Pakistan
Background Gender norms determine the status of Pakistani women that influence their life including health. In Pakistan, the relationship between gender norms and health of women is crucial yet complex demanding further analysis. This paper: determines the reasons for reiteration of gender roles; describes the societal processes and mechanisms that reproduce and reinforce them; and identifies their repercussions on womenâs personality, lives and health especially reproductive health. Methods As part of a six-country study titled âWomenâs Empowerment in Muslim Contextsâ, semi-structured group discussions (nâ=â30) were conducted with women (nâ=â250) who were selected through snowballing from different age, ethnic and socio-economic categories. Discussion guidelines were used to collect participantâs perceptions about Pakistani womenâs: characteristics, powers, aspirations, needs and responsibilities; circumstances these women live in such as opportunities, constraints and risks; and influence of these circumstances on their personality, lifestyle and health. Results The society studied has constructed a âModelâ for women that consider them âObjectsâ without rights and autonomy. Womenâs subordination, a prerequisite to ensure compliance to the constructed model, is maintained through allocation of lesser resources, restrictions on mobility, seclusion norms and even violence in cases of resistance. The model determines womenâs traits and responsibilities, and establishes parameters for what is legitimate for women, and these have implications for their personality, lifestyle and health, including their reproductive behaviours. Conclusion There is a strong link between womenâs autonomy, rights, and health. This demands a gender sensitive and a, right-based approach towards health. In addition to service delivery interventions, strategies are required to counter factors influencing health status and restricting access to and utilization of services. Improvement in womenâs health is bound to have positive influences on their children and wider familyâs health, education and livelihood; and in turn on a societyâs health and economy
Correlation of lipid profile and anthropometry with aortic intima-media thickness in newborns of diabetic and non-diabetic mothers
Background: Exposure to diabetes in utero has been established as a significant factor for certain component of the clinical syndrome. Although complications of atherosclerosis occur in adult life, the process begins in early childhood. Hence, measuring aortic intima-media thickness (AIMT) in the newborn is a feasible, accurate, and sensitive marker of atherosclerotic risk. Objective: The objective of the study was to find an association of AIMT with cord blood lipid levels and anthropometric factors. Methods: Babies born to diabetic mothers (gestational diabetes mellitus/type 2 diabetes mellitus (34 weeksâ42 weeks) who were taken as one group and babies born to non-diabetic mothers (34 weeksâ42 weeks) who were taken as the other group were enrolled in this study. Lipid values were measured of umbilical cord blood, collected immediately after delivery. Atherogenic-indices were calculated; neonatal anthropometric measurements were taken within 24 h after delivery. Abdominal AIMT (aAIMT) was measured within 4 days of delivery using a high-resolution ultrasound B mode by a trained radiologist. Maternal age, parity, height, pre-pregnancy weight, gestational age, and other investigations were taken from maternal records. Results: In this study, birth weight (BW) was positively correlated with triglycerides (TG), cholesterol, high-density lipoprotein (HDL), very low-density lipoprotein (VLDL), and atherogenic-indices, whereas, it was negatively correlated with low-density lipoprotein (LDL) (p<0.01). A positive correlation was found between aAIMT and BW, abdominal circumference, TG, cholesterol, HDL, LDL, VLDL, and atherogenic-indices (p<0.001). Conclusions: In this study, infants born to diabetic mothers had higher anthropometry, lipid values, aAIMT compared to babies born to non-diabetic mothers without risk factors
Giant Size Pilocytic Astrocytoma in Pediatric Patient : A Case Report
Introduction: Pilocytic astrocytomas are the most common primary tumor in children and adolescents, accounting for approximately 15.6% of all brain tumors and 5.4% of all gliomas. The incidence of tumors substantially decreases with age and diagnosis in patients older than 50 years is less common. According to the Central Brain Tumor Registry of the United States (CBTRUS), its development is more common in the first two decades of life and there are few reports in the age group over 18 years.
Case Report: An 8-year-old girl was brought by her parents with complaints of loss of consciousness. This happened 2 days before admission to the hospital. The patient was prepared for craniotomy tumor removal. During the operation, the tumor specimen was sent to Anatomical Pathology for histopathological examination. The examination revealed calcified Rosenthal Fibers and eosinophilic granular bodies.
Discussion : Astrocytic tumors originate from neuroepithelial tissue and are grade I because of their well-defined and slow-growing nature. They are mostly found in infratentorial structures such as the cerebellum and in the midline of brain structures such as the optic nerve, hypothalamus, and brainstem. However, it can be found anywhere on the neuroaxis. Considered relatively rare in adults, there are few publications on the most efficient treatment methods and subsequent patient outcomes.
Conclusion: Pilocytic astrocytoma (PA) treated with complete or near complete tumor resection tends to have a better prognosis, recent studies recommend aggressive tumor resection without neurologic deficits
HCV genotype-specific correlation with serum markers: Higher predictability for genotype 4a
Several factors have been proposed to assess the clinical outcome of HCV infection. The correlation of HCV genotypes to possible serum markers in clinical prediction is still controversial. The main objective of this study was to determine the existence of any correlation between HCV genotypes to viral load and different clinical serum markers.We performed a prospective cross-sectional and observational study. About 3160 serum HCV RNA positive patients were chosen from 4020 randomly selected anti-HCV positive patients. Statistical analysis was performed using the SPSS 16 software package. ROC (receiver operating characteristics) curves were used to compare diagnostic values of serum markers to predict genotypes.The most prevalent genotype was 3a (73.9%) followed by 1a (10.7%), 4a (6.4%) and 3b (6.1%) in Pakistani population. No correlation was found between viral load and serum markers for genotype 3a in a large no. of sample (n = 2336). While significant correlation was observed between viral load and AST in genotype 3b, ALP with viral load and ALT for genotype 1a. Patients with genotype 4a showed a significant inverse correlation with viral load and Hb level and AST with ALP. For genotype 4a, AUC (area under the curve) of ALT, ALP, AST, bilirubin, Hb level and viral load was 0.790, 0.763, 0.454, 0.664, 0.458 and 0.872 respectively.In conclusion, there was a significant variable response of HCV genotypes with serum markers. Severity of disease is independent of serum marker level in genotype 3a, while the liver damage in genotype 4a may associate with viral cytopathic effect as well as the immune-mediated process. An index using six serum markers may correctly predict genotype 4a in patients with ⼠75% accuracy
Claudin-1 required for HCV virus entry has high potential for phosphorylation and O-glycosylation
HCV is a leading cause of hepatocellular carcinoma and cirrhosis all over the world. Claudins belong to family of tight junction's proteins that are responsible for establishing barriers for controlling the flow of molecules around cells. For therapeutic strategies, regulation of viral entry into the host cells holds a lot of promise. During HCV infection claudin-1 is highly expressed in liver and believed to be associated with HCV virus entry after HCV binding with or without co-receptor CD81. The claudin-1 assembly with tight junctions is regulated by post translational modifications. During claudins assembly and disassembly with tight junctions, phosphorylation is required at C-terminal tail. In cellular proteins, interplay between phosphorylation and O-β-GlcNAc modification is believed to be functional switch, but it is very difficult to monitor these functional and vibrant changes in vivo. Netphos 2.0 and Disphos 1.3 programs were used for potential phosphorylation; NetPhosK 1.0 and KinasePhos for kinase prediction; and YinOYang 1.2 and OGPET to predict possible O-glycosylation sites. We also identified Yin Yang sites that may have potential for O-β-GlcNAc and phosphorylation interplay at same Ser/Thr residues. We for the first time proposed that alternate phosphorylation and O-β-GlcNAc modification on Ser 192, Ser 205, Ser 206; and Thr 191 may provide an on/off switch to regulate assembly of claudin-1 at tight junctions. In addition these phosphorylation sites may be targeted by novel chemotherapeutic agents to prevent phosphorylation lead by HCV viral entry complex
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