Multiple traffic signal control using a genetic algorithm

Optimising traffic signal timings for a multiple-junction road network is a difficult but important problem. The essential difficulty of this problem is that the traffic signals need to coordinate their behaviours to achieve the common goal of optimising overall network delay. This paper discusses a novel approach towards the generation of optimal signalling strategies, based on the use of a genetic algorithm (GA). This GA optimises the set of signal timings for all junctions in network. The different efficient red and green times for all the signals are determined by genetic algorithm as well as the offset time for each junction. Previous attempts to do this rely on a fixed cycle time, whereas the algorithm described here attempts to optimise cycle time for each junction as well as proportion of green times. The fitness function is a measure of the overall delay of the network. The resulting optimised signalling strategies were compared against a well-known civil engineering technique, and conclusions drawn

Initial POLAR MFE observation of substorm signatures in the polar magnetosphere

This paper studies substorm influences in the polar magnetosphere using data from the POLAR magnetic field experiment (MFE). The POLAR spacecraft remains in the high altitude polar magnetosphere for extended periods around apogee. There it can stay at nearly constant altitude through all phases of a substorm, which was not possible on previous missions. We report such an event on March 28, 1996. Ground magnetometers monitored substorm activity, while the POLAR spacecraft, directly over the pole at (−0.8, −0.6, 8.5) RE in GSM coordinates, observed a corresponding perturbation in the total magnetic field strength. The total magnetic field first increased, then recovered toward quiet levels, consistent with erosion of magnetic flux from the dayside magnetosphere, followed by transport of that flux to the magnetotail, and eventual onset of tail reconnection and the return of that magnetic flux to the dayside magnetosphere

Barriers and predictors of medication use for childhood ADHD: findings from a UK population-representative cohort

This is the final version. Available from Springer Verlag via the DOI in this record.Purpose Little is known about sociodemographic and clinical factors that predict and act as barriers to ADHD medication independently of symptom severity. We examined the proportion of children using medication for ADHD, age of initiation of medication, and predictors of medication use in a population-representative cohort. Methods Data from the Millennium Cohort Study on child ADHD, medication use for ADHD at age 14 (in 2014–2015) and child, parent and sociodemographic variables were collated. Logistic regression models were used to identify factors that predict medication use for ADHD (the main outcome measure), adjusting for symptom severity at age seven. Results The weighted prevalence of ADHD was 3.97% (N = 11,708). 45.57% of children with ADHD (N = 305) were taking medication. The median age at initiation was 9 years (range 3–14). Male gender (AOR 3.66, 95% CI 1.75, 7.66) and conduct problems at age seven (AOR 1.24 95% CI 1.04, 1.47) and 14 predicted medication use at age 14 after adjusting for symptom severity. Conclusions Our study is the first to assess predictors of medication whist adjusting for ADHD symptom severity. Girls with ADHD were less likely to be prescribed medication, even when they displayed similar ADHD symptom levels to boys. Conduct problems also predicted medication independently of ADHD symptoms. ADHD may be more often medicated in boys because clinicians may think a prototypical ADHD child is male, and perhaps conduct problems make boys more disruptive in the classroom, leading to boys being more often treated.Wellcome Trus

Fusion of neurohypophyseal membranes in vitro

Freeze cleaving electron microscopy has shown that fusion of isolated secretory vesicles from bovine neurohypophyses was induced by Ca 2+ in micromolar concentrations. Mg 2+ and Sr 2+ were ineffective. Mg 2+ inhibited Ca 2+-induced fusion. In suspensions containing secretory vesicles as well as sheets of cell membrane, release of vasopressin parallel to intervesicular fusion of secretory vesicles with sheets of cell membrane was observed after exposure to Ca 2+. Mg 2+ and Sr 2+ were ineffective in replacing Ca 2+ as trigger for fusion or vasopressin release. Intervesicular fusion and exocytotic profiles were observed when isolated neurohypophyses or neurosecretosome were exposed to cold

On inward motion of the magnetopause preceding a substorm

Magnetopause inward motion preceding magnetic storms observed by means of OGO-E magnetomete

A technology development program for large space antennas

The design and application of the offset wrap rib and the maypole (hoop/column) antenna configurations are described. The NASA mission model that generically categorizes the classes of user requirements, as well as the methods used to determine critical technologies and requirements are discussed. Performance estimates for the mesh deployable antenna selected for development are presented

Apollo particles and fields subsatellite magnetometer experiment

The results of the Apollo 15 subsatellite magnetometer experiment are reported. The magnetometer is described including the operation, and specifications. Orbit plots presented are altitude versus time, selenographic longitude versus latitude, and the ecliptic projection of the earth-moon system. The lunar magnetic field, solar wind interaction with the moon, the transfer function of the moon, and the plasma sheet interaction with the moon are discussed