603 research outputs found
The Effect of Music Tempo on Squat Performance
Burket, J., Eubank, T., Reed, C., Sanders, J. Shippensburg University, Shippensburg, PA
Purpose: The purpose of this study was to determine whether music tempo affects squat performance. Methods: A total of eleven healthy college aged subjects (Age range: 18 ~ 22 yrs, Weight: 81.4±12.0 kg, Height: 1.7±0.1 m) volunteered in the study and eight subjects (one female and seven males) completed the study. After obtaining baseline measures, subjects performed heavy barbell squat exercise under three conditions. The three conditions were to perform the squat exercise with load equal to 60% of their body weight until failure while listening to fast tempo (200 bpm), slow tempo (60 bpm) and no music. The order of the trial was randomized and each trial was separated by a minimum of 7 days. Using descriptive statistics and one-way analysis of variance, data were analyzed to compare the difference in performance under three conditions. Results: Compared to fast music and no music condition, subjects performed more repetition of squat under slow music condition (34.8±29.6 vs. 33.5±22.7 vs. 35.1± 37.0 reps). However, the difference was not significant (p\u3e0.05). Although not significant, subjects reported higher rate of perceived exertion (RPE) under slow music condition while exercise heart rate and systolic blood pressure were reported to be lower with slow music condition. Conclusion: The results of the study indicate that music tempo has no significant influence on heavy squat exercise performance or cardiovascular measures during exercise. Future studies are needed to further examine possible effect of music tempo when using a larger variation
Identifying influential spreaders and efficiently estimating infection numbers in epidemic models: a walk counting approach
We introduce a new method to efficiently approximate the number of infections
resulting from a given initially-infected node in a network of susceptible
individuals. Our approach is based on counting the number of possible infection
walks of various lengths to each other node in the network. We analytically
study the properties of our method, in particular demonstrating different forms
for SIS and SIR disease spreading (e.g. under the SIR model our method counts
self-avoiding walks). In comparison to existing methods to infer the spreading
efficiency of different nodes in the network (based on degree, k-shell
decomposition analysis and different centrality measures), our method directly
considers the spreading process and, as such, is unique in providing estimation
of actual numbers of infections. Crucially, in simulating infections on various
real-world networks with the SIR model, we show that our walks-based method
improves the inference of effectiveness of nodes over a wide range of infection
rates compared to existing methods. We also analyse the trade-off between
estimate accuracy and computational cost, showing that the better accuracy here
can still be obtained at a comparable computational cost to other methods.Comment: 6 page
Social stress-enhanced severity of Citrobacter rodentium-induced colitis is CCL2-dependent and attenuated by probiotic Lactobacillus reuteri
Psychological stressors are known to affect colonic diseases but the mechanisms by which this occurs, and whether probiotics can prevent stressor effects, are not understood. Because inflammatory monocytes that traffic into the colon can exacerbate colitis, we tested whether CCL2, a chemokine involved in monocyte recruitment, was necessary for stressor-induced exacerbation of infectious colitis. Mice were exposed to a social disruption stressor that entails repeated social defeat. During stressor exposure, mice were orally challenged with Citrobacter rodentium to induce a colonic inflammatory response. Exposure to the stressor during challenge resulted in significantly higher colonic pathogen levels, translocation to the spleen, increases in colonic macrophages, and increases in inflammatory cytokines and chemokines. The stressor-enhanced severity of C. rodentium-induced colitis was not evident in CCL2[superscript −/−] mice, indicating the effects of the stressor are CCL2-dependent. In addition, we tested whether probiotic intervention could attenuate stressor-enhanced infectious colitis by reducing monocyte/macrophage accumulation. Treating mice with probiotic Lactobacillus reuteri reduced CCL2 mRNA levels in the colon and attenuated stressor-enhanced infectious colitis. These data demonstrate that probiotic L. reuteri can prevent the exacerbating effects of stressor exposure on pathogen-induced colitis, and suggest that one mechanism by which this occurs is through downregulation of the chemokine CCL2.National Cancer Institute (U.S.) (Grants AT006552-01A1, P30-CA016058, and T32-DE014320
Singular Value Decomposition of Operators on Reproducing Kernel Hilbert Spaces
Reproducing kernel Hilbert spaces (RKHSs) play an important role in many
statistics and machine learning applications ranging from support vector
machines to Gaussian processes and kernel embeddings of distributions.
Operators acting on such spaces are, for instance, required to embed
conditional probability distributions in order to implement the kernel Bayes
rule and build sequential data models. It was recently shown that transfer
operators such as the Perron-Frobenius or Koopman operator can also be
approximated in a similar fashion using covariance and cross-covariance
operators and that eigenfunctions of these operators can be obtained by solving
associated matrix eigenvalue problems. The goal of this paper is to provide a
solid functional analytic foundation for the eigenvalue decomposition of RKHS
operators and to extend the approach to the singular value decomposition. The
results are illustrated with simple guiding examples
All roads lead to Rome, but Rome wasn’t built in a day. Advice on QSEP navigation from the ‘Roman Gods’ of assessment!
Rome was the point of convergence of all the main roads of the Roman Empire. When Roman emperor Caesar Augustus erected the ‘Milliarium Aureum’ (Golden Milestone) in the heart of Ancient Rome, all roads were designed to begin at the monument. Metaphorically, the ancient proverb ‘All roads lead to Rome’ means there are many different ways of reaching the same goal or conclusion. QSEP training is a bit like that, with trainees engaging with so many different types of clients, settings, cultures, approaches and interventions that no two portfolios of work look alike. Yet, the competency demonstration ‘end goal’ is the same. The ancient Romans were also wise; they knew that in building their Roman empire (or for us building relationships and competence as Sport and Exercise Psychologists), doing something important or creating a masterpiece takes the time it takes; ‘Rome wasn’t built in a day’ and, metaphorically, QSEP is not something to rush or smear with impatience either
Don't bleach chaotic data
A common first step in time series signal analysis involves digitally
filtering the data to remove linear correlations. The residual data is
spectrally white (it is ``bleached''), but in principle retains the nonlinear
structure of the original time series. It is well known that simple linear
autocorrelation can give rise to spurious results in algorithms for estimating
nonlinear invariants, such as fractal dimension and Lyapunov exponents. In
theory, bleached data avoids these pitfalls. But in practice, bleaching
obscures the underlying deterministic structure of a low-dimensional chaotic
process. This appears to be a property of the chaos itself, since nonchaotic
data are not similarly affected. The adverse effects of bleaching are
demonstrated in a series of numerical experiments on known chaotic data. Some
theoretical aspects are also discussed.Comment: 12 dense pages (82K) of ordinary LaTeX; uses macro psfig.tex for
inclusion of figures in text; figures are uufile'd into a single file of size
306K; the final dvips'd postscript file is about 1.3mb Replaced 9/30/93 to
incorporate final changes in the proofs and to make the LaTeX more portable;
the paper will appear in CHAOS 4 (Dec, 1993
Sensitivity of Household Transmission to Household Contact Structure and Size
Study the influence of household contact structure on the spread of an influenza-like illness. Examine whether changes to in-home care giving arrangements can significantly affect the household transmission counts.We simulate two different behaviors for the symptomatic person; either s/he remains at home in contact with everyone else in the household or s/he remains at home in contact with only the primary caregiver in the household. The two different cases are referred to as full mixing and single caregiver, respectively.The results show that the household's cumulative transmission count is lower in case of a single caregiver configuration than in the full mixing case. The household transmissions vary almost linearly with the household size in both single caregiver and full mixing cases. However the difference in household transmissions due to the difference in household structure grows with the household size especially in case of moderate flu.These results suggest that details about human behavior and household structure do matter in epidemiological models. The policy of home isolation of the sick has significant effect on the household transmission count depending upon the household size
Bayesian Best-Arm Identification for Selecting Influenza Mitigation Strategies
Pandemic influenza has the epidemic potential to kill millions of people.
While various preventive measures exist (i.a., vaccination and school
closures), deciding on strategies that lead to their most effective and
efficient use remains challenging. To this end, individual-based
epidemiological models are essential to assist decision makers in determining
the best strategy to curb epidemic spread. However, individual-based models are
computationally intensive and it is therefore pivotal to identify the optimal
strategy using a minimal amount of model evaluations. Additionally, as
epidemiological modeling experiments need to be planned, a computational budget
needs to be specified a priori. Consequently, we present a new sampling
technique to optimize the evaluation of preventive strategies using fixed
budget best-arm identification algorithms. We use epidemiological modeling
theory to derive knowledge about the reward distribution which we exploit using
Bayesian best-arm identification algorithms (i.e., Top-two Thompson sampling
and BayesGap). We evaluate these algorithms in a realistic experimental setting
and demonstrate that it is possible to identify the optimal strategy using only
a limited number of model evaluations, i.e., 2-to-3 times faster compared to
the uniform sampling method, the predominant technique used for epidemiological
decision making in the literature. Finally, we contribute and evaluate a
statistic for Top-two Thompson sampling to inform the decision makers about the
confidence of an arm recommendation
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