53 research outputs found

    Choice of Law in Product Liability Actions: Order for the Practitioner in a Reign of Chaos

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    The law on choice of law in the various states and in the federal courts is a veritable jungle, which, if the law can be found out, leads not to a rule of action but a reign of chaos dominated in each case by the judge\u27s informed guess as to what some other state than the one in which he sits would hold its law to be. Products move today in streams of commerce which cross state, and often international, boundaries. When litigation concerning the liability for injury or damage caused by these products follows, choice of law plays a crucial role in determining the rights, remedies, and defenses available to the parties. In this article, the authors identify the issues which plaintiffs and defendants should consider in multi-jurisdictional product liability actions and set forth the basic rules for tort and contract choice of law

    Structure of deformed silicon and implications for low cost solar cells

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    The microstructure and minority carrier lifetime of silicon were investigated in uniaxially compressed silicon samples. The objective of the investigation was to determine if it is feasible to produce silicon solar cells from sheet formed by high temperature rolling. The initial structure of the silicon samples ranged from single crystal to fine-grained polycrystals. The samples had been deformed at strain rates of 0.1 to 8.5/sec and temperatures of 1270-1380 C with subsequent annealing at 1270-1380 C. The results suggest that high temperature rolling of silicon to produce sheet for cells of high efficiency is not practical

    New Insights in the Contribution of Voltage-Gated Nav Channels to Rat Aorta Contraction

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    BACKGROUND: Despite increasing evidence for the presence of voltage-gated Na(+) channels (Na(v)) isoforms and measurements of Na(v) channel currents with the patch-clamp technique in arterial myocytes, no information is available to date as to whether or not Na(v) channels play a functional role in arteries. The aim of the present work was to look for a physiological role of Na(v) channels in the control of rat aortic contraction. METHODOLOGY/PRINCIPAL FINDINGS: Na(v) channels were detected in the aortic media by Western blot analysis and double immunofluorescence labeling for Na(v) channels and smooth muscle alpha-actin using specific antibodies. In parallel, using real time RT-PCR, we identified three Na(v) transcripts: Na(v)1.2, Na(v)1.3, and Na(v)1.5. Only the Na(v)1.2 isoform was found in the intact media and in freshly isolated myocytes excluding contamination by other cell types. Using the specific Na(v) channel agonist veratridine and antagonist tetrodotoxin (TTX), we unmasked a contribution of these channels in the response to the depolarizing agent KCl on rat aortic isometric tension recorded from endothelium-denuded aortic rings. Experimental conditions excluded a contribution of Na(v) channels from the perivascular sympathetic nerve terminals. Addition of low concentrations of KCl (2-10 mM), which induced moderate membrane depolarization (e.g., from -55.9+/-1.4 mV to -45.9+/-1.2 mV at 10 mmol/L as measured with microelectrodes), triggered a contraction potentiated by veratridine (100 microM) and blocked by TTX (1 microM). KB-R7943, an inhibitor of the reverse mode of the Na(+)/Ca(2+) exchanger, mimicked the effect of TTX and had no additive effect in presence of TTX. CONCLUSIONS/SIGNIFICANCE: These results define a new role for Na(v) channels in arterial physiology, and suggest that the TTX-sensitive Na(v)1.2 isoform, together with the Na(+)/Ca(2+) exchanger, contributes to the contractile response of aortic myocytes at physiological range of membrane depolarization

    Choice of Law in Product Liability Actions: Order for the Practitioner in a Reign of Chaos

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    The law on choice of law in the various states and in the federal courts is a veritable jungle, which, if the law can be found out, leads not to a rule of action but a reign of chaos dominated in each case by the judge\u27s informed guess as to what some other state than the one in which he sits would hold its law to be. Products move today in streams of commerce which cross state, and often international, boundaries. When litigation concerning the liability for injury or damage caused by these products follows, choice of law plays a crucial role in determining the rights, remedies, and defenses available to the parties. In this article, the authors identify the issues which plaintiffs and defendants should consider in multi-jurisdictional product liability actions and set forth the basic rules for tort and contract choice of law
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