Spin-polarized transport in ferromagnetic multilayered semiconductor nanostructures

The occurrence of inhomogeneous spin-density distribution in multilayered ferromagnetic diluted magnetic semiconductor nanostructures leads to strong dependence of the spin-polarized transport properties on these systems. The spin-dependent mobility, conductivity and resistivity in (Ga,Mn)As/GaAs,(Ga,Mn)N/GaN, and (Si,Mn)/Si multilayers are calculated as a function of temperature, scaled by the average magnetization of the diluted magnetic semiconductor layers. An increase of the resistivity near the transition temperature is obtained. We observed that the spin-polarized transport properties changes strongly among the three materials.Comment: 3 pages, 4 figure

Fundaments of the ethical acting in university students

It is urgent that the superior Education in the health area develops in the students a pro-active ethical commitment which is translated into the creation of socio-professional and rational and clarified socio-cultural values.info:eu-repo/semantics/publishedVersio

Severe hyperchloremic metabolic acidosis with SGLT2 inhibitors in patients with urinary diversion

info:eu-repo/semantics/publishedVersio

Bioenergetic dysfunction in Huntington's disease human cybrids

In this work we studied the mitochondrial-associated metabolic pathways in Huntington's disease (HD) versus control (CTR) cybrids, a cell model in which the contribution of mitochondrial defects from patients is isolated. HD cybrids exhibited an interesting increase in ATP levels, when compared to CTR cybrids. Concomitantly, we observed increased glycolytic rate in HD cybrids, as revealed by increased lactate/pyruvate ratio, which was reverted after inhibition of glycolysis. A decrease in glucose-6-phosphate dehydrogenase activity in HD cybrids further indicated decreased rate of the pentose-phosphate pathway. ATP levels of HD cybrids were significantly decreased under glycolysis inhibition, which was accompanied by a decrease in phosphocreatine. Nevertheless, pyruvate supplementation could not recover HD cybrids' ATP or phosphocreatine levels, suggesting a dysfunction in mitochondrial use of that substrate. Oligomycin also caused a decrease in ATP levels, suggesting a partial support of ATP generation by the mitochondria. Nevertheless, mitochondrial NADH/NAD(t) levels were decreased in HD cybrids, which was correlated with a decrease in pyruvate dehydrogenase activity and protein expression, suggesting decreased tricarboxylic acid cycle (TCA) input from glycolysis. Interestingly, the activity of alpha-ketoglutarate dehydrogenase, a critical enzyme complex that links the TCA to amino acid synthesis and degradation, was increased in HD cybrids. In accordance, mitochondrial levels of glutamate were increased and alanine was decreased, whereas aspartate and glutamine levels were unchanged in HD cybrids. Conversely, malate dehydrogenase activity from total cell extracts was unchanged in HD cybrids. Our results suggest that inherent dysfunction of mitochondria from HD patients affects cellular bioenergetics in an otherwise functional nuclear background

Tratamento Compulsivo em Regime de Ambulatório: desafios no processo ensino-aprendizagem

No estágio V - Enfermagem de Saúde Mental e Psiquiatria, desenvolvido numa equipa comunitária existiu a oportunidade de participar no processo de cuidados a pessoas com doença mental submetidas a Tratamento Compulsivo em Regime de Ambulatório. Esta medida decorre da Lei de Saúde Mental (Lei nº36/98 de 24 de julho) e permite à pessoa realizar o tratamento inserida na comunidade - “sempre que seja possível manter esse tratamento em liberdade”. Esta experiência constituiu-se numa mais valia ao nível do processo ensinoaprendizagem, na medida em que permitiu analisar diferentes aspetos da realidade da pessoa. Objetivos Partilhar a reflexão sobre a experiência de prestação de cuidados à pessoa com doença mental sob Tratamento Compulsivo em Regime de Ambulatório. Materiais e Métodos Como metodologia utiliza-se o Ciclo Reflexivo de Gibbs (Santos e Fernandes, 2004), cuja função é promover e possibilitar a melhor e mais detalhada análise de determinada situação. Resultados A reflexão sobre a ação desenvolvida no âmbito do processo de cuidados à pessoa submetida a Tratamento Compulsivo em Regime Ambulatório permitiu compreender que as pessoas que estão sujeitas a este tipo de medida apresentam uma reduzida Adesão ao Regime Terapêutico e facilitou a análise da tomada de decisão face às situações concretas. Conclusões O desenvolvimento do processo de cuidados à pessoa submetida a Tratamento Compulsivo em Regime Ambulatório possibilitou a experienciação da prestação de cuidados num contexto que colocou diferentes questões, que permitiram um processo de reflexão sobre a tomada de decisão e as aprendizagens realizadas. Relevância para a Enfermagem A Organização Mundial de Saúde (2004, p.10) define Saúde Mental como “um estado de bem-estar em que o indivíduo reconhece as suas próprias capacidades, consegue lidar com as tensões normais da vida, pode trabalhar de forma produtiva e proveitosa, e é capaz de contribuir para a sua comunidade”, desta forma a saúde mental constitui-se como fundamental na vida da pessoa. Referências bibliográficas Lei nº 36/98 de 24 de julho. Diário da República Eletrónico - 1-A. Assembleia da República. Lisboa. Disponível em: https://data.dre.pt/eli/lei/36/1998/p/cons/20180814/pt/html Organização Mundial da Saúde. (2004) Promoting Mental Health: Concepts, Emerging Evidence, Practice. Summary Report. A report of the World Health Organization, Department of Mental Health and Substance Abuse in collaboration with the Victorian Health Promotion Foundation and the University of Melbourne. Genebra: OMS. Disponível em: https://www.who.int/mental_health/evidence/en/promoting_mhh.pdf Santos, E.; Fernandes, A. (2004). Prática Reflexiva: Guia para a Reflexão Estruturada. Revista Referência, (11), 59-62. Disponível em: https://rr.esenfc.pt/rr/index.php?module=rr&target=publicationDetails&pesquisa=&id_a rtigo=2064&id_revista=5&id_edicao=10N/

Influence of the soil on sensorial characteristics of Petit Verdot tropical wines from the Northeast of Brazil.

The objective of this work was to evaluate Petit Verdot varietal wines elaborate from grapes of vines cultivated in three types of soils, sandy, gravelly and clayey, different on physical and chemical characteristics, being sandy and clayey argisoils and gravelly cambosoil, by enologists

Influence of the soil on sensorial characteristics of Petit Verdot tropical wines from the Northeast of Brazil.

The objective of this work was to evaluate Petit Verdot varietal wines elaborate from grapes of vines cultivated in three types of soils, sandy, gravelly and clayey, different on physical and chemical characteristics, being sandy and clayey argisoils and gravelly cambosoil, by enologists

Contribution of PRS3, RPB4 and ZWF1 to the resistance of industrial Saccharomyces cerevisiae CCUG53310 and PE-2 strains to lignocellulosic hydrolysate-derived inhibitors

PRS3, RPB4 and ZWF1 were previously identified as key genes for yeast tolerance to lignocellulose-derived inhibitors. To better understand their contribution to yeast resistance to the multiple stresses occurring during lignocellulosic hydrolysate fermentations, we overexpressed these genes in two industrial Saccharomyces cerevisiae strains, CCUG53310 and PE-2, and evaluated their impact on the fermentation of Eucalyptus globulus wood and corn cob hydrolysates. PRS3 overexpression improved the fermentation rate (up to 32%) and productivity (up to 48%) in different hydrolysates. ZWF1 and RPB4 overexpression did not improve the fermentation performance, but their increased expression in the presence of acetic acid, furfural and hydroxymethylfurfural was found to contribute to yeast adaptation to these inhibitors. This study expands our understanding about the molecular mechanisms involved in industrial yeast tolerance to the stresses occurring during lignocellulosic bioethanol production and highlights the importance of selecting appropriate strain backgrounds/hydrolysates combinations when addressing further improvement of these processes.Fundação para a Ciência e a Tecnologia, Portugal, through: Grant SFRH/BDP/63831/2009 to Grant SFRH/BPD/77995/2011; Strategic Project PEst-OE/EQB/LA0023/2013; and Project BioInd NORTE-07-0124-FEDER-000028 co-funded by the Programa Operacional Regional do Norte (ON.2 – O Novo Norte), QREN, FEDER