298 research outputs found
Identification and ethnic diversity underlie support for multicultural rights : a multilevel analysis in Bulgaria
Bulgaria is historically a multicultural society, composed of the Bulgarian (ethnic) majority and a number of ethnic minorities among which Bulgarian Turks and Roma are the largest. Both minority communities are stigmatized in contemporary Bulgaria, though to different degrees and for different reasons. Ethnic minorities' rights to preserve their culture, customs, and language are a topic of contentious debate. The purpose of this study was to examine individual- and context-level antecedents of the ethnic Bulgarian majority's support for multicultural rights of ethnic minorities. Multilevel regression analyses were conducted with International Social Survey Programme ISSP 2003 data (N = 920 in 28 Bulgarian districts). At the individual-level, an ethnic conception of the nation and anti-Roma symbolic prejudice were negatively related to support for multicultural rights, whereas national identification was positively related to the support of these rights. Over and above individual-level effects, and in line with recent extensions of intergroup contact theory, thepercentage ofBulgarianTurks withindistricts was positively related to support for multicultural rights. Importantly, support for multicultural rights was particularly high in districts characterized by ethnic diversity, that is, in districts with high proportions of both Bulgarian Turks and Roma. The beneficial effects of ethnic diversity and theoretical implications of findings are discussed
Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin
Semiconductor nanoparticles (quantum dots) are promising fluorescent markers, but it is very little known about interaction of quantum dots with biological molecules. In this study, interaction of CdTe quantum dots coated with thioglycolic acid (TGA) with bovine serum albumin was investigated. Steady state spectroscopy, atomic force microscopy, electron microscopy and dynamic light scattering methods were used. It was explored how bovine serum albumin affects stability and spectral properties of quantum dots in aqueous media. CdTe–TGA quantum dots in aqueous solution appeared to be not stable and precipitated. Interaction with bovine serum albumin significantly enhanced stability and photoluminescence quantum yield of quantum dots and prevented quantum dots from aggregating
Characterization of CdSe nanocrystals coated with amphiphiles. A capillary electrophoresis study
We have synthesized CdSe nanocrystals (NCs) possessing a trioctylphosphine surface passivation layer and modified with amphiphilic molecules to form a surface bilayer. The NCs covered with single amphiphiles are not stable in aqueous solution, but a mixed amphiphilic system is shown to provide stability in solution over several months. The solutions of the modified NCs were characterized by UV-Vis absorbance, photoluminescence, and transmission electron microscopy. An electrophoretic study revealed two operational modes. The first relies on the enrichment of NCs using a micellar plug as a tool. The accumulation of NCs at the plug-electrolyte buffer interface results in a sharp peak. By controlling the electrophoretic conditions, nanocrystals were forced to exit a micellar plug into an electrolyte buffer. We conclude that a system consisting of modified nanocrystals and a micellar plug can act as a mixed pseudomicellar system, where modified nanocrystals play the role of pseudomicelles
Studies on the response of a water-Cherenkov detector of the Pierre Auger Observatory to atmospheric muons using an RPC hodoscope
Extensive air showers, originating from ultra-high energy cosmic rays, have been successfully measured through the use of arrays of water-Cherenkov detectors (WCDs). Sophisticated analyses exploiting WCD data have made it possible to demonstrate that shower simulations, based on different hadronic-interaction models, cannot reproduce the observed number of muons at the ground. The accurate knowledge of the WCD response to muons is paramount in establishing the exact level of this discrepancy. In this work, we report on a study of the response of a WCD of the Pierre Auger Observatory to atmospheric muons performed with a hodoscope made of resistive plate chambers (RPCs), enabling us to select and reconstruct nearly 600 thousand single muon trajectories with zenith angles ranging from 0 to 55. Comparison of distributions of key observables between the hodoscope data and the predictions of dedicated simulations allows us to demonstrate the accuracy of the latter at a level of 2%. As the WCD calibration is based on its response to atmospheric muons, the hodoscope data are also exploited to show the long-term stability of the procedure
Reconstruction of events recorded with the surface detector of the Pierre Auger Observatory
Cosmic rays arriving at Earth collide with the upper parts of the atmosphere, thereby inducing extensive air showers. When secondary particles from the cascade arrive at the ground, they are measured by surface detector arrays. We describe the methods applied to the measurements of the surface detector of the Pierre Auger Observatory to reconstruct events with zenith angles less than 60 using the timing and signal information recorded using the water-Cherenkov detector stations. In addition, we assess the accuracy of these methods in reconstructing the arrival directions of the primary cosmic ray particles and the sizes of the induced showers
Design, upgrade and characterization of the silicon photomultiplier front-end for the AMIGA detector at the Pierre Auger Observatory
AMIGA (Auger Muons and Infill for the Ground Array) is an upgrade of the Pierre Auger Observatory to complement the study of ultra-high-energy cosmic rays (UHECR) by measuring the muon content of extensive air showers (EAS). It consists of an array of 61 water Cherenkov detectors on a denser spacing in combination with underground scintillation detectors used for muon density measurement. Each detector is composed of three scintillation modules, with 10 m2 detection area per module, buried at 2.3 m depth, resulting in a total detection area of 30 m2. Silicon photomultiplier sensors (SiPM) measure the amount of scintillation light generated by charged particles traversing the modules. In this paper, the design of the front-end electronics to process the signals of those SiPMs and test results from the laboratory and from the Pierre Auger Observatory are described. Compared to our previous prototype, the new electronics shows a higher performance, higher efficiency and lower power consumption, and it has a new acquisition system with increased dynamic range that allows measurements closer to the shower core. The new acquisition system is based on the measurement of the total charge signal that the muonic component of the cosmic ray shower generates in the detector
Measurement of the Fluctuations in the Number of Muons in Extensive Air Showers with the Pierre Auger Observatory
We present the first measurement of the fluctuations in the number of muons in extensive air showers produced by ultrahigh energy cosmic rays. We find that the measured fluctuations are in good agreement with predictions from air shower simulations. This observation provides new insights into the origin of the previously reported deficit of muons in air shower simulations and constrains models of hadronic interactions at ultrahigh energies. Our measurement is compatible with the muon deficit originating from small deviations in the predictions from hadronic interaction models of particle production that accumulate as the showers develop.Fil: Aab, A.. Radboud Universiteit Nijmegen; Países BajosFil: Abreu, P.. Instituto Superior Tecnico; PortugalFil: Aglietta, M.. Osservatorio Astrofisico di Torino; Italia. Istituto Nazionale di Astrofisica; Italia. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Albury, J. M.. University of Adelaide; AustraliaFil: Allekotte, Ingomar. Comisión Nacional de Energía Atómica. Gerencia del Área de Energía Nuclear. Instituto Balseiro; Argentina. Comisión Nacional de Energía Atómica. Centro Atómico Bariloche; ArgentinaFil: Almela, Daniel Alejandro. Universidad Tecnológica Nacional; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Tecnología en Detección y Astropartículas. Comisión Nacional de Energía Atómica. Instituto de Tecnología en Detección y Astropartículas. Universidad Nacional de San Martín. Instituto de Tecnología en Detección y Astropartículas; ArgentinaFil: Alvarez Muñiz, J.. Universidad de Santiago de Compostela; EspañaFil: Alves Batista, R.. Radboud Universiteit Nijmegen; Países BajosFil: Anastasi, G. A.. Università di Torino; Italia. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Anchordoqui, L.. University of New York; Estados UnidosFil: Andrada, María Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Tecnología en Detección y Astropartículas. Comisión Nacional de Energía Atómica. Instituto de Tecnología en Detección y Astropartículas. Universidad Nacional de San Martín. Instituto de Tecnología en Detección y Astropartículas; ArgentinaFil: Andringa, S.. Instituto Superior Tecnico; PortugalFil: Aramo, C.. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Araújo Ferreira, P. R.. Rwth Aachen University; AlemaniaFil: Asorey, Hernán Gonzalo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Tecnología en Detección y Astropartículas. Comisión Nacional de Energía Atómica. Instituto de Tecnología en Detección y Astropartículas. Universidad Nacional de San Martín. Instituto de Tecnología en Detección y Astropartículas; ArgentinaFil: Assis, P.. Instituto Superior Tecnico; PortugalFil: Avila, Gualberto. Observatorio Pierre Auger. Observatorio Sur - Malargue; Argentina. Comisión Nacional de Energía Atómica; ArgentinaFil: Badescu, A. M.. University Politehnica of Bucharest; RumaniaFil: Bakalova, A.. Czech Academy of Sciences; República ChecaFil: Balaceanu, A.. “Horia Hulubei” National Institute for Physics and Nuclear Engineering; RumaniaFil: Barbato, F.. Università degli Studi di Napoli Federico II; Italia. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Barreira Luz, R. J.. Instituto Superior Técnico; PortugalFil: Becker, K. H.. Bergische Universität Wuppertal; AlemaniaFil: Bellido, J. A.. University of Adelaide; AustraliaFil: Berat, C.. Universite Grenoble Alpes; Francia. Centre National de la Recherche Scientifique; FranciaFil: Bertaina, M. E.. Università di Torino; Italia. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Bertou, Xavier Pierre Louis. Comisión Nacional de Energía Atómica. Gerencia del Área de Energía Nuclear. Instituto Balseiro; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Area Investigación y Aplicaciones No Nucleares. Gerencia de Física (Centro Atómico Bariloche). Grupo de Partículas y Campos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; ArgentinaFil: Biermann, P. L.. Max-Planck-Institut für Radioastronomie; AlemaniaFil: Bister, T.. Aachen University; AlemaniaFil: Mollerach, Maria Silvia. Comisión Nacional de Energía Atómica. Gerencia del Área de Investigación y Aplicaciones No Nucleares. Gerencia de Física (Centro Atómico Bariloche); Argentina. Comisión Nacional de Energía Atómica. Gerencia del Área de Energía Nuclear. Instituto Balseiro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; Argentin
Design, upgrade and characterization of the silicon photomultiplier front-end for the AMIGA detector at the Pierre Auger Observatory
AMIGA (Auger Muons and Infill for the Ground Array) is an upgrade of the Pierre Auger Observatory to complement the study of ultra-high-energy cosmic rays (UHECR) by measuring the muon content of extensive air showers (EAS). It consists of an array of 61 water Cherenkov detectors on a denser spacing in combination with underground scintillation detectors used for muon density measurement. Each detector is composed of three scintillation modules, with 10 m2 detection area per module, buried at 2.3 m depth, resulting in a total detection area of 30 m2 . Silicon photomultiplier sensors (SiPM) measure the amount of scintillation light generated by charged particles traversing the modules. In this paper, the design of the front-end electronics to process the signals of those SiPMs and test results from the laboratory and from the Pierre Auger Observatory are described. Compared to our previous prototype, the new electronics shows a higher performance, higher efficiency and lower power consumption, and it has a new acquisition system with increased dynamic range that allows measurements closer to the shower core. The new acquisition system is based on the measurement of the total charge signal that the muonic component of the cosmic ray shower generates in the detector.Fil: Aab, A.. Radboud Universiteit Nijmegen; Países BajosFil: Abreu, P.. Instituto Superior Tecnico; PortugalFil: Aglietta, M.. Istituto Nazionale di Astrofisica; Italia. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Albury, J. M.. University of Adelaide; AustraliaFil: Allekotte, Ingomar. Comisión Nacional de Energía Atómica. Gerencia del Área de Energía Nuclear. Instituto Balseiro; ArgentinaFil: Almela, A.. Universidad Nacional de San Martín; Argentina. Universidad Tecnológica Nacional; ArgentinaFil: Alvarez Muñiz, J.. Universidad de Santiago de Compostela; EspañaFil: Alves Batista, R.. Radboud Universiteit Nijmegen; Países BajosFil: Anastasi, G. A.. Università di Torino; Italia. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Anchordoqui, Luis A.. City University of New York; Estados UnidosFil: Andrada, Betiana Eugenia. Universidad Nacional de San Martín; ArgentinaFil: Andringa, S.. Instituto Superior Tecnico; PortugalFil: Aramo, C.. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Araújo Ferreira, P. R.. Rwth Aachen University; AlemaniaFil: Asorey, H.. Universidad Nacional de San Martín; ArgentinaFil: Assis, P.. Instituto Superior Tecnico; PortugalFil: Avila, G.. Observatorio Pierre Auger; ArgentinaFil: Badescu, A. M.. University Politehnica Of Bucharest; RumaniaFil: Bakalova, A.. The Czech Academy Of Sciences; República ChecaFil: Balaceanu, A.. “Horia Hulubei” National Institute for Physics and Nuclear Engineering, Bucharest-Magurele; RumaniaFil: Barbato, F.. Università degli Studi di Napoli Federico II; Italia. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Barreira Luz, R. J.. Instituto Superior Tecnico; PortugalFil: Becker, K. H.. Bergische Universität Wuppertal; AlemaniaFil: Bellido, J. A.. University of Adelaide; AustraliaFil: Berat, C.. Universite Grenoble Alpes; FranciaFil: Bertaina, M. E.. Università di Torino; Italia. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Bertou, Xavier Pierre Louis. Comisión Nacional de Energía Atómica. Gerencia del Área de Energía Nuclear. Instituto Balseiro; ArgentinaFil: Biermann, P. L.. Max Planck Institute For Radio Astronomy; AlemaniaFil: Bister, T.. Rwth Aachen University; AlemaniaFil: Gollan Scilipotti, Fernando Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Tecnología en Detección y Astropartículas. Comisión Nacional de Energía Atómica. Instituto de Tecnología en Detección y Astropartículas. Universidad Nacional de San Martín. Instituto de Tecnología en Detección y Astropartículas; Argentin
The Photodynamic Effect of Different Size ZnO Nanoparticles on Cancer Cell Proliferation In Vitro
Nanomaterials have widely been used in the field of biological and biomedicine, such as tissue imaging, diagnosis and cancer therapy. In this study, we explored the cytotoxicity and photodynamic effect of different-sized ZnO nanoparticles to target cells. Our observations demonstrated that ZnO nanoparticles exerted dose-dependent and time-dependent cytotoxicity for cancer cells like hepatocellular carcinoma SMMC-7721 cells in vitro. Meanwhile, it was observed that UV irradiation could enhance the suppression ability of ZnO nanoparticles on cancer cells proliferation, and these effects were in the size-dependent manner. Furthermore, when ZnO nanoparticles combined with daunorubicin, the related cytotoxicity of anticancer agents on cancer cells was evidently enhanced, suggesting that ZnO nanoparticles could play an important role in drug delivery. This may offer the possibility of the great potential and promising applications of the ZnO nanoparticles in clinical and biomedical areas like photodynamic cancer therapy and others
Capillary electrophoretic separation of nanoparticles
In the present work, CdSe nanocrystals (NCs) synthesized with a trioctylphosphine surface passivation layer were modified using amphiphilic molecules to form a surface bilayer capable of providing stable NCs aqueous solutions. Such modified nanocrystals were used as a test solute in order to analyze new electrophoretic phenomena, by applying a micellar plug as a separation tool for discriminating nanocrystals between micellar and micelle-free zones during electrophoresis. The distribution of NCs between both zones depended on the affinity of nanocrystals towards the micellar zone, and this relies on the kind of surface ligands attached to the NCs, as well as electrophoretic conditions applied. In this case, the NCs that migrated within a micellar zone can be focused using a preconcentration mechanism. By modifying electrophoretic conditions, NCs were forced to migrate outside the micellar zone in the form of a typical CZE peak. In this situation, a two-order difference in separation efficiencies, in terms of theoretical plates, was observed between focused NCs (N ~ 107) and a typical CZE peak for NCs (N ~ 105). By applying the amino-functionalized NCs the preconcentration of NCs, using a micellar plug, was examined, with the conclusion that preconcentration efficiency, in terms of the enhancement factor for peak height (SEFheight) can be, at least 20. The distribution effect was applied to separate CdSe/ZnS NCs encapsulated in silica, as well as surface-modified with DNA, which allows the estimation of the yield of conjugation of biologically active molecules to a particle surface
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