175 research outputs found
Inviscid incompressible limits of the full Navier-Stokes-Fourier system
We consider the full Navier-Stokes-Fourier system in the singular limit for
the small Mach and large Reynolds and Peclet numbers, with ill prepared initial
data on the three dimensional Euclidean space. The Euler-Boussinesq
approximation is identified as the limit system
Stability with respect to domain of the low Mach number limit of compressible viscous fluids
We study the asymptotic limit of solutions to the barotropic Navier-Stokes
system, when the Mach number is proportional to a small parameter \ep \to 0
and the fluid is confined to an exterior spatial domain \Omega_\ep that may
vary with \ep. As , it is shown that the fluid
density becomes constant while the velocity converges to a solenoidal vector
field satisfying the incompressible Navier-Stokes equations on a limit domain.
The velocities approach the limit strongly (a.a.) on any compact set, uniformly
with respect to a certain class of domains. The proof is based on spectral
analysis of the associated wave propagator (Neumann Laplacian) governing the
motion of acoustic waves.Comment: 32 page
RNA polymerase II stalling promotes nucleosome occlusion and pTEFb recruitment to drive immortalization by Epstein-Barr virus
Epstein-Barr virus (EBV) immortalizes resting B-cells and is a key etiologic agent in the development of numerous cancers. The essential EBV-encoded protein EBNA 2 activates the viral C promoter (Cp) producing a message of ~120 kb that is differentially spliced to encode all EBNAs required for immortalization. We have previously shown that EBNA 2-activated transcription is dependent on the activity of the RNA polymerase II (pol II) C-terminal domain (CTD) kinase pTEFb (CDK9/cyclin T1). We now demonstrate that Cp, in contrast to two shorter EBNA 2-activated viral genes (LMP 1 and 2A), displays high levels of promoter-proximally stalled pol II despite being constitutively active. Consistent with pol II stalling, we detect considerable pausing complex (NELF/DSIF) association with Cp. Significantly, we observe substantial Cp-specific pTEFb recruitment that stimulates high-level pol II CTD serine 2 phosphorylation at distal regions (up to +75 kb), promoting elongation. We reveal that Cp-specific pol II accumulation is directed by DNA sequences unfavourable for nucleosome assembly that increase TBP access and pol II recruitment. Stalled pol II then maintains Cp nucleosome depletion. Our data indicate that pTEFb is recruited to Cp by the bromodomain protein Brd4, with polymerase stalling facilitating stable association of pTEFb. The Brd4 inhibitor JQ1 and the pTEFb inhibitors DRB and Flavopiridol significantly reduce Cp, but not LMP1 transcript production indicating that Brd4 and pTEFb are required for Cp transcription. Taken together our data indicate that pol II stalling at Cp promotes transcription of essential immortalizing genes during EBV infection by (i) preventing promoter-proximal nucleosome assembly and ii) necessitating the recruitment of pTEFb thereby maintaining serine 2 CTD phosphorylation at distal regions
Wave: A New Family of Trapdoor One-Way Preimage Sampleable Functions Based on Codes
We present here a new family of trapdoor one-way Preimage Sampleable
Functions (PSF) based on codes, the Wave-PSF family. The trapdoor function is
one-way under two computational assumptions: the hardness of generic decoding
for high weights and the indistinguishability of generalized -codes.
Our proof follows the GPV strategy [GPV08]. By including rejection sampling, we
ensure the proper distribution for the trapdoor inverse output. The domain
sampling property of our family is ensured by using and proving a variant of
the left-over hash lemma. We instantiate the new Wave-PSF family with ternary
generalized -codes to design a "hash-and-sign" signature scheme which
achieves existential unforgeability under adaptive chosen message attacks
(EUF-CMA) in the random oracle model. For 128 bits of classical security,
signature sizes are in the order of 15 thousand bits, the public key size in
the order of 4 megabytes, and the rejection rate is limited to one rejection
every 10 to 12 signatures.Comment: arXiv admin note: text overlap with arXiv:1706.0806
Birkhoff Normal form for Gravity Water Waves
We consider the gravity water waves system with a one-dimensional periodic interface in infinite depth, and present the proof of the rigorous reduction of these equations to their cubic Birkhoff normal form (Berti et al. in Birkhoff normal form and long-time existence for periodic gravity Water Waves. arXiv:1810.11549, 2018). This confirms a conjecture of Zakharov\u2013Dyachenko (Phys Lett A 190:144\u2013148, 1994) based on the formal Birkhoff integrability of the water waves Hamiltonian truncated at degree four. As a consequence, we also obtain a long-time stability result: periodic perturbations of a flat interface that are of size \u3b5 in a sufficiently smooth Sobolev space lead to solutions that remain regular and small up to times of order \u3b5 123
Modeling and Navigation Filtering for Spacecraft Rendezvous with Flexible Appendages and Sloshing
Time quasi-periodic gravity water waves in finite depth
We prove the existence and the linear stability of Cantor families of small amplitude time quasi-periodic standing water wave solutions\u2014namely periodic and even in the space variable x\u2014of a bi-dimensional ocean with finite depth under the action of pure gravity. Such a result holds for all the values of the depth parameter in a Borel set of asymptotically full measure. This is a small divisor problem. The main difficulties are the fully nonlinear nature of the gravity water waves equations\u2014the highest order x-derivative appears in the nonlinear term but not in the linearization at the origin\u2014and the fact that the linear frequencies grow just in a sublinear way at infinity. We overcome these problems by first reducing the linearized operators, obtained at each approximate quasi-periodic solution along a Nash\u2013Moser iterative scheme, to constant coefficients up to smoothing operators, using pseudo-differential changes of variables that are quasi-periodic in time. Then we apply a KAM reducibility scheme which requires very weak Melnikov non-resonance conditions which lose derivatives both in time and space. Despite the fact that the depth parameter moves the linear frequencies by just exponentially small quantities, we are able to verify such non-resonance conditions for most values of the depth, extending degenerate KAM theory
Cross standard form : a solution to improve a given controller with H2 or Hoo specifications
This paper introduces in cross standard form (CSF) as a solution to the inverse optimal control problem. That is, the CSF is a canonical standard problem whose unique H1 or H2 optimal controller is a given controller. From the control design point of view, the general idea is to apply the CSF to a given controller in order to set up a standard problem which can be completed to handle frequency domain H2 or H1 specification. The analytical formulation of the CSF proposed in this paper can be applied to reduced-, full- or augmented-order compensators or two-degree of freedom compensations. Numerical and academic examples are given
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