PEGylated calix[4]arene as a carrier for a Bodipy-based photosensitizer

Cataloged from PDF version of article.Heavy atom substituted Bodipy compounds, unlike the parent chromophore, undergo rapid intersystem crossing to generate singlet oxygen, which is the primary cytotoxic agent exploited in PDT. In this work, we show that an organic soluble calix[4]arene can be functionalized by Knoevenagel reaction and then converted into an amphiphilic photosensitizer in a few steps. In addition to generating a potentially useful photosensitizer, the sequence of reactions is the first use of a Bodipy dye as a chromophoric/fluorogenic label without the typical reactive functional groups. 2013 Elsevier Ltd. All rights reserved

Fast Responding and Selective Near-IR Bodipy Dye for Hydrogen Sulfide Sensing

Cataloged from PDF version of article.A Bodipy based, highly selective probe for hydrogen sulfide has been designed, synthesized and demonstrated to detect H2S in living cells. In this design, the reduction of two arylazido groups change the charge transfer characteristics of the 3,5-distyryl substituents on the Bodipy core, producing a 20 nm bathochromic spectral shift in the absorption band, and quenching of the emission by 85% compared to the original intensity, through photoinduced electron transfer

Tetrastyryl-BODIPY-Based Dendritic Light Harvester and Estimation of Energy Transfer Efficiency

Cataloged from PDF version of article.Versatile BODIPY dyes can be transformed into bright near-IR-emitting fluorophores by quadruple styryl substitutions. When clickable functionalities on the styryl moieties are inserted, an efficient synthesis of a light harvester is possible. In addition, clear spectral evidence is presented showing that, in dendritic light harvesters, calculations commonly based on quantum yield or emission lifetime changes of the donor are bound to yield large overestimations of energy transfer efficiency

Chromogenic and Fluorogenic Sensing of Biological Thiols in Auqeous Solutions Using BODIPY-Based Reagents

Cataloged from PDF version of article.udicious design of BODIPY dyes carrying nitroethenyl substituents in conjugation with the BODIPY core yields dyes that respond to biological thiols by both absorbance and emission changes. Incorporation of solubilizing ethyleneglycol units ensures water solubility. The result is bright signaling of biologically relevant thiols in the longer wavelength region of the visible spectrum and in aqueous solutions

Near-IR-Triggered, Remote-Controlled Release of Metal Ions: A Novel Strategy for Caged Ions

Cataloged from PDF version of article.A ligand incorporating a dithioethenyl moiety is cleaved into fragments which have a lower metal-ion affinity upon irradiation with low-energy red/near-IR light. The cleavage is a result of singlet oxygen generation which occurs on excitation of the photosensitizer modules. The method has many tunable factors that could make it a satisfactory caging strategy for metal ions

“Smartphone apps are cool, but do they help me?”: A qualitative interview study of adolescents’ perspectives on using smartphone interventions to manage nonsuicidal self-injury

Nonsuicidal self-injury (NSSI) is a major mental health problem associated with negative psychosocial outcomes and it most often starts in early adolescence. Despite this, adolescents are rarely involved in informing the development of interventions designed to address their mental health problems. This study aimed to (1) assess adolescents’ needs and preferences about future interventions that are delivered through smartphones and (2) develop a framework with implications for designing engaging digital mental health interventions. Fifteen adolescent girls, aged 12– 18 years, who met diagnostic criteria for a current NSSI disorder and were in contact with mental health services, participated in semi-structured interviews. Following a reflexive thematic analysis approach, this study identified two main themes: (1) Experiences of NSSI (depicts the needs of young people related to their everyday experiences of managing NSSI) and (2) App in Context (por-trays preferences of young people about smartphone interventions and reflects adolescents’ views on how technology itself can improve or hinder engaging with these interventions). Adolescent patients expressed interest in using smartphone mental health interventions if they recognize them as helpful, relevant for their life situation and easy to use. The developed framework suggests that digital mental health interventions are embedded in three contexts (i.e., person using the interven-tion, mental health condition, and technology-related factors) which together need to inform the development of engaging digital resources. To achieve this, the cooperation among people with lived experience, mental health experts, and human computer interaction professionals is vital

Selective Hg(II) sensing with improved stokes shift by coupling the internal charge transfer process to excitation energy transfer

Versatile chemistry of the Bodipy chromophore allows modular assembly of an excitation energy donor, acceptor, and a cation selective ligand in just a couple of steps. The new approach should be applicable in other designs which target molecular sensors with large Stokes shifts and red to near IR emission. © 2010 American Chemical Society

A sensitive and selective ratiometric near IR fluorescent probe for zinc ions based on the distyryl-bodipy fluorophore

(Chemical Equation Presented) A novel distyryl-substituted boradiazaindacene (bodipy) dye with an emission peak moving hypsochromically from 730 to 680 nm on Zn(II) ion binding seems to be promising as one of the very few water-soluble fluorescent chemosensors emitting in the near IR region. © 2008 American Chemical Society

Modular logic gates: cascading independent logic gates via metal ion signals

Cataloged from PDF version of article.Abstract Systematic cascading of molecular logic gates is an important issue to be addressed for advancing research in this field. We have demonstrated that photochemically triggered metal ion signals can be utilized towards that goal. Thus, independent logic gates were shown to work together while keeping their identity in more complex logic designs. Communication through the intermediacy of ion signals is clearly inspired from biological processes modulated by such signals, and implemented here with ion responsive molecules. © 2014 The Royal Society of Chemistry.

Design and synthesis of soluble dibenzosuberane-substituted fullerene derivatives for bulk-heterojunction polymer solar cells

Cataloged from PDF version of article.Two new dibenzosuberane-substituted fullerene derivatives, dibenzosuberane-C60 monoadduct (DBSCMA) and bis-adduct (DBSCBA) were synthesized using a classical cyclopropanation reaction via a tosylhydrazone route for application as acceptor materials in polymer solar cells (PSCs). DBSCBA shows good solubility in common organic solvents and both derivatives were characterized by 1HNMR, 13C NMR, MALD-TOF, elemental analysis and UV-vis absorption measurements. The shift of fullerene energy levels induced by the dibenzosuberane substitution was investigated by using theoretical simulations and ultraviolet photoelectron spectroscopy. Bulk-heterojunction PSCs based on poly (3-hexylthiophene) (P3HT) and dibenzosuberane-C60 derivatives were fabricated and optimized by adjusting the donor/acceptor ratio and using thermal annealing and solvent additive. The morphologies of the active layers processed under different conditions were also examined by atomic force microscopy. When tested under an illumination of AM 1.5 G at 100 mW/ cm2, the highest power conversion efficiency of the devices using DBSCBA is 3.70% which is superior to that of conventional P3HT:PCBM devices. © 2013 Elsevier B.V