7 research outputs found
Disruption prediction with artificial intelligence techniques in tokamak plasmas
- Author
- Abid N.
- Abraham K.
- Abreu P.
- Adabonyan O.
- Adrich P.
- Afanasev V.
- Afzal M.
- Ahlgren T.
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- Alekseev A.G.
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- Algualcil J.
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- Yaala M. Ben
- Yadykin Dimitriy
- Yajima M.
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- Young I.
- Young R.
- Zabolockis R.J.
- Zacks J.
- Zag\uf3rski R.
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- Zoulias I.
- Zwingmann W.
- Zychor I.
- Łaszyr\uedska E.
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
In nuclear fusion reactors, plasmas are heated to very high temperatures of more than 100 million kelvin and, in so-called tokamaks, they are confined by magnetic fields in the shape of a torus. Light nuclei, such as deuterium and tritium, undergo a fusion reaction that releases energy, making fusion a promising option for a sustainable and clean energy source. Tokamak plasmas, however, are prone to disruptions as a result of a sudden collapse of the system terminating the fusion reactions. As disruptions lead to an abrupt loss of confinement, they can cause irreversible damage to present-day fusion devices and are expected to have a more devastating effect in future devices. Disruptions expected in the next-generation tokamak, ITER, for example, could cause electromagnetic forces larger than the weight of an Airbus A380. Furthermore, the thermal loads in such an event could exceed the melting threshold of the most resistant state-of-the-art materials by more than an order of magnitude. To prevent disruptions or at least mitigate their detrimental effects, empirical models obtained with artificial intelligence methods, of which an overview is given here, are commonly employed to predict their occurrence—and ideally give enough time to introduce counteracting measures
Runaway electron beam control
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- Adamek J.
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- Łaszyńska E.
- Šesnić S.
- Šušnjara A.
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2019
- Field of study
Post-disruption runaway electron (RE) beams in tokamaks with large current can cause deep melting of the vessel and are one of the major concerns for ITER operations. Consequently, a considerable effort is provided by the scientific community in order to test RE mitigation strategies. We present an overview of the results obtained at FTU and TCV controlling the current and position of RE beams to improve safety and repeatability of mitigation studies such as massive gas (MGI) and shattered pellet injections (SPI). We show that the proposed RE beam controller (REB-C) implemented at FTU and TCV is effective and that current reduction of the beam can be performed via the central solenoid reducing the energy of REs, providing an alternative/parallel mitigation strategy to MGI/SPI. Experimental results show that, meanwhile deuterium pellets injected on a fully formed RE beam are ablated but do not improve RE energy dissipation rate, heavy metals injected by a laser blow off system on low-density flat-top discharges with a high level of RE seeding seem to induce disruptions expelling REs. Instabilities during the RE beam plateau phase have shown to enhance losses of REs, expelled from the beam core. Then, with the aim of triggering instabilities to increase RE losses, an oscillating loop voltage has been tested on RE beam plateau phase at TCV revealing, for the first time, what seems to be a full conversion from runaway to ohmic current. We finally report progresses in the design of control strategies at JET in view of the incoming SPI mitigation experiments
Real-time-capable prediction of temperature and density profiles in a tokamak using RAPTOR and a first-principle-based transport model
- Author
- Abduallev S.
- Abhangi M.
- Abreu P.
- Adamek J.
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- Yadykin Dimitriy
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- Zychor I.
- Łaszyńska E.
- Šesnić S.
- Šušnjara A.
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2018
- Field of study
The RAPTOR code is a control-oriented core plasma profile simulator with various applications in control design and verification, discharge optimization and real-time plasma simulation. To date, RAPTOR was capable of simulating the evolution of poloidal flux and electron temperature using empirical transport models, and required the user to input assumptions on the other profiles and plasma parameters. We present an extension of the code to simulate the temperature evolution of both ions and electrons, as well as the particle density transport. A proof-of-principle neural-network emulation of the quasilinear gyrokinetic QuaLiKiz transport model is coupled to RAPTOR for the calculation of first-principle-based heat and particle turbulent transport. These extended capabilities are demonstrated in a simulation of a JET discharge. The multi-channel simulation requires ∼0.2 s to simulate 1 second of a JET plasma, corresponding to ∼20 energy confinement times, while predicting experimental profiles within the limits of the transport model. The transport model requires no external inputs except for the boundary condition at the top of the H-mode pedestal. This marks the first time that simultaneous, accurate predictions of Te, Tiand nehave been obtained using a first-principle-based transport code that can run in faster-than-real-time for present-day tokamaks
Comparison of runaway electron generation parameters in small, medium-sized and large tokamaks - A survey of experiments in COMPASS, TCV, ASDEX-Upgrade and JET
- Author
- Abduallev S.
- Abhangi M.
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- Zoletnik S.
- Zuin M.
- Zychor I.
- Łaszyńska E.
- Šesnić S.
- Šušnjara A.
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2018
- Field of study
This paper presents a survey of the experiments on runaway electrons (RE) carried out recently in frames of EUROFusion Consortium in different tokamaks: COMPASS, ASDEX-Upgrade, TCV and JET. Massive gas injection (MGI) has been used in different scenarios for RE generation in small and medium-sized tokamaks to elaborate the most efficient and reliable ones for future RE experiments. New data on RE generated at disruptions in COMPASS and ASDEX-Upgrade was collected and added to the JET database. Different accessible parameters of disruptions, such as current quench rate, conversion rate of plasma current into runaways, etc have been analysed for each tokamak and compared to JET data. It was shown, that tokamaks with larger geometrical sizes provide the wider limits for spatial and temporal variation of plasma parameters during disruptions, thus extending the parameter space for RE generation. The second part of experiments was dedicated to study of RE generation in stationary discharges in COMPASS, TCV and JET. Injection of Ne/Ar have been used to mock-up the JET MGI runaway suppression experiments. Secondary RE avalanching was identified and quantified for the first time in the TCV tokamak in RE generating discharges after massive Ne injection. Simulations of the primary RE generation and secondary avalanching dynamics in stationary discharges has demonstrated that RE current fraction created via avalanching could achieve up to 70-75% of the total plasma current in TCV. Relaxations which are reminiscent the phenomena associated to the kinetic instability driven by RE have been detected in RE discharges in TCV. Macroscopic parameters of RE dominating discharges in TCV before and after onset of the instability fit well to the empirical instability criterion, which was established in the early tokamaks and examined by results of recent numerical simulations
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- Author
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- Gazibegovic N
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- Gl\uf6ckner C
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- Goranovic T
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- Simonsen M
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- Soro M
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- Soto TT
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- Soumpasis I
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- Spagnolo L
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- Spyropoulou E
- Spyropoulou-Pagdatoglou K
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- Steib A
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- Stepanovs J
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- Stier M
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- Tamowicz B
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- Taylor A
- Templeton M
- Tena B
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- Theodorou V
- Thibaud A
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- Thomas J
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- Thomas R
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- Tibblin AO
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- Toft P
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- Unterberg M
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- Utrera FA
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- van Bommel J
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- Verhamme B
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- Vicente R
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- Vincent JL
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- Vitor P
- Vizca\uedno M
- Vizcaychipi M
- Vojinovic R
- von Heymann C
- Voulas A
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- Wagner J
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- Wasmund C
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- Weber M
- Weda T
- Wepler U
- Wernerman J
- Wessels K
- Westbrook A
- Westbrook A
- Weyland A
- White N
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- Wickboldt N
- Wiegand-L\uf6hnert C
- Wiese O
- Wigmore T
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- Wintzheimer S
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- Wollaston J
- Wong K
- Wong P
- Woolhead A
- Worton R
- Wright C
- Wright M
- Wyldbore M
- Yemnga B
- Yepes MJ
- Yeung J
- Ytrebo LM
- Zaballos J
- Zabarte M
- Zacharouli D
- Zacharovska A
- Zadrazilova K
- Zafiridis T
- Zahorec R
- Zahorec R
- Zaldibar E
- Zamora JF
- Zandvliet R
- Zantua K
- Zearo E
- Zeba S
- Ziekenhuis A
- Zittling R
- Zocca E
- Zoltowski MK
- Zompanti V
- Zsisku L
- Zunic F
- Zuzan O
- Publication venue
- Publication date
- 01/01/2012
- Field of study
Second asymptomatic carotid surgery trial (ACST-2) : a randomised comparison of carotid artery stenting versus carotid endarterectomy
- Author
- \u160ercl Miroslav
- \u160koloud\uedk David
- \u160tekl\ue1cov\ue1 Anna
- Abd-Allah Foad
- Abdul-Hamiq Ahmed
- Abdulamit Timur
- Accrocca Federico
- Acosta Stefan
- Ahlhelm Frank J
- Aidashova Balzhan
- Akyea-Mensah Joyce
- Albuquerque e Castro Jo\ue3o
- Aleksic Nikola
- Allaire Eric
- Almekhlafi Mohammed A
- Alonso Angelika
- Alves Gon\ue7alo
- Alwis Lanka
- Amatucci Giovanni
- Ambrogi Cesare
- Amis Deborah
- Anderson Dawn
- Andonova Silva
- Andziak Piotr
- Angiletta Domenico
- Angus Jane
- Antonopoulos Constantine N
- Aparici Robles Fernando
- Argentieri Angelo
- Arnold Sebastian
- Ashleigh Ray
- Ashley Simon
- Asokanathan Asaipillai
- Astarci Parla
- Babic Srdan
- Bachvarov Chavdar
- Baht Hardeep
- Bajardi Guido
- Bajoriene Milda
- Baker Lucy
- Bakke S\uf8ren
- Bal Simerpreet
- Ball Stephen
- Balogun Ibrahim
- Barbazza Renzo
- Barber Phillip A
- Barer David
- Bari Vasha
- Barlinn Jessica
- Bartko Daniel
- Barwell James
- Barz\uf3 P\ue1l
- Bastos Gon\ue7alves Frederico
- Bausback Yvonne
- Beard Jonathan
- Becquemin Jean-Pierre
- Belcastro Fernando
- Bellenis Ion
- Belli Anna
- Bellini Dalio Marcelo
- Belyasnik Andrey
- Bene\u161 III Vladim\uedr
- Benevento Domenico
- Beno Peter
- Berekoven B\ue4rbel
- Berg Bengt
- Berger Hermann
- Bergeron Patrice
- Bernardini Giulia
- Berry Clive
- Beyar Rafi
- Bialek Pawel
- Bianchi Paolo
- Bicknell Colin
- Biejat Zbigniew
- Biermaier Bernhard
- Bir\uf3 G\ue1bor
- Birt Angela
- Bj\uf6rses Katarina
- Blackham Kristine
- Blanco Ca\uf1ibano Estrella
- Blanes Orti Paula
- Bodosi Mihaly
- Bombic Martin
- Bonati Leo H
- Bonati Leo H
- Borger Franka
- Bosiers Marc
- Botsios Spiridon
- Br\ue4unlich Sven
- Bradshaw S
- Brandt Kerstin
- Branzan Daniela
- Briley Dennis
- Brountzos Elias
- Brown Andrew
- Brown Ellen
- Brown Ellen
- Brown James
- Brown Pauline
- Brudlo Wojciech
- Bryce Jenny
- Buchvald Pavel
- Bulbulia Richard
- Bulbulia Richard
- Burger Ilse
- Burzotta Francesco
- Butterfield Stephen
- C\uf6ster Andreas
- Callaert Joren
- Campbell Erik
- Campos Jr Walter
- Cannizzaro Alfredo
- Cao Piergiorgio
- Capoccia Laura
- Cappelli Alessandro
- Cardon Jean-Marie
- Carimati Federico
- Casana Renato
- Casella Ivan B
- Caso Valeria
- Catterson Martin
- Cernetti Carlo
- Chamorro \uc1ngel
- Chataway Jeremy
- Chatzinikou Eleni
- Chechulov Pavel
- Chernyavsky Mikhail A
- Cheshire Nicholas
- Chester Johanna
- Chester Johanna
- Chetter Ian
- Chiarandini Stefano
- Chisci Emiliano
- Chlouba Vladim\uedr
- Chrisopoulou Angela
- Cieri Enrico
- Cirelli Silvana
- Cireni Lea
- Civilini Efrem
- Clarke Alison
- Clarke Mike
- Clarke Sandra
- Cleveland Trevor
- Clifton Andrew
- Clifton Andrew
- Cochennec-Paliwoda Fr\ue9d\ue9ric
- Codispoti Francesco Alberto
- Colgan Mary P
- Colic Momcilo
- Colston Amanda
- Coppi Elisabetta
- Coppi Gioacchino
- Corbetta Riccardo
- Cosier Tracy
- Coutts Shelagh B
- Cowie Linda
- Cox Robin
- Cradduck-Bamford Andrea
- Cradduck-Bamford Andrea
- Cras Patrick
- Crawford Susan
- Crinnion Jamie
- Csobay-Nov\ue1k Csaba
- Cuenoud Larissa
- Cura Fernando
- Cvetic Vladimir
- Cvjetko Ivan
- Czepel Wojciech
- Czlonkowska Anna
- D'Angelo Costantino L
- D'Oria Mario
- D'Souza Stephen
- D\uf3sa Edit
- da Silva Erasmo S
- Dabek Pawel
- Darby Chris
- Davey Philip
- Davidovic Lazar
- Davies Paul
- Davis Michelle
- de Arag\ue3o Morais Jos\ue9
- de Borst Gert J
- De Donato Gianmarco
- De Koster Guy
- de Luccia Nelson
- Debus Eike S
- Dei Negri Massimo
- Delle Martin
- Delodovici Maria Luisa
- Deloose Koen
- DeMarco Ester
- Demchuk Andrew M
- DeRango Paola
- Desantis Claudio
- Desgranges Pascal
- Desiron Quentin
- Di Lazzaro Vincenzo
- Dias Nuno
- Dienel Cora
- Dieng Mortalla
- Diepers Michael
- Dix Francis
- Dixit Anand
- Donnelly Mary
- Dormal Pol
- Dorman Paul
- Dowzenko Anatol
- Dratwicki Maciej
- Drelichowski Stanislaw
- Dunlop Paul
- Durairajan Ragunath
- Dutta Dipankar
- Dyker Alexander
- Dzieciuchowicz Lukasz
- Eckstein Hans-Henning
- Eesa Muneer
- Egun Anselm A
- Eldessoki Mohamed H
- Eley Caroline
- Eliot-Jones Bekky
- Emerson Lorraine
- Endo Hidenori
- Endrych Ladislav
- Enevoldson Peter
- Engelhardt Andreas
- Engelter Stefan
- Entz L\ue1szl\uf3
- Esisi Bernard
- Estenssoro Andr\ue9 E V
- Ettles Duncan
- Eugster Thomas
- Ezura Masayuki
- F\ue1k\uf3 Eniko
- F\ufcl\uf6p B\ue9la
- Fadda Gian Franco
- Faggioli Gianluca
- Farchioni Luca
- Farrell Barbara
- Fathers Susan
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- Ferrero Emanuele
- Ferri Michelangelo
- Fiedler Jir\ued
- Flather Marcus
- Flis Vojko
- Fontana Federico
- Ford Gary
- Formgren Johan
- Fornolles Caroline
- Fraedrich Gustav
- Frerker Klaus
- Furui Eisuke
- G\ufcnther Albrecht
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- G\ufcrke Lorenz
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- Gabriel Marcin
- Gaggiano Andrea
- Gaines Peter
- Galeotti Roberto
- Gamble Ed
- Garc\ueda Dominguez Luis
- Garc\ueda Fresnillo Beatriz
- Garcia Ana C
- Gargiulo Mauro
- Gasbarro Vincenzo
- Gasparini Mladen
- Geenens Mia
- Gemper Janine
- Gensicke Henrik
- George Jim
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- Ghosh Jonathan
- Giannoukas Athanasios
- Giaquinta Alessia
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- Gillgren Peter
- Gillies Michelle
- Gissler Hans Martin
- Gizewski Elke
- Golovkova Maria S
- Gordon Vera
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- Gough Michael
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- Grad Anton
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- Gray Richard
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- Grimaldi Luigi
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- Groden Christoph
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- Gruber Philipp
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- Grzyska Ulrich
- Guerra Requena Mercedes
- Gunathilagan Gunaratnam
- Guyler Paul
- H\uf6lzer Henryk
- Haase Kathrin
- Haider Syed N
- Halliday Alison
- Halliday Alison
- Halu\u17ean Damir
- Hamady Mohammad
- Hammer Frank
- Hands Linda
- Harbison Joe
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- Hartmann Christian
- Hayter Elizabeth
- Hazel Beth
- Heiling Bianka
- Hemelsoet Dimitri
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- Herrington Will
- Hes Karel
- Heshmat Kassem Hussein
- Hill Michael D
- Hilltout Paula
- Hoffman Aaron
- Holliday Constance
- Holst Jan
- Hoppenbrouwers Mieke
- Hosseini Hassan
- Howard Dominic
- Hrb\ue1c Tom\ue1\u161
- Hudon Mark E
- Hughes Andrea
- Humphreys John
- Hunte Sophy
- Ignatenko Pavel
- Ilijevski Nenad
- Inoue Takashi
- Insall Robert
- Ioannou Nikolaos
- Irsara Sandro
- Isaak Andrej
- Isernia Giacomo
- Iwanowski Wojciech
- Jackson Ralph
- Jahrome Ommid
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- James Alex
- Jarl Lotta
- Jedrzejewska Julia
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- Jenkins Michael
- Jochmann Elisabeth
- Jones Deborah
- Jones Sally
- Jonker Leon
- Joseph Thomas
- Joseph Thomas
- Jovanovic Dejana R
- Joviliano Edwaldo E
- Judge Parminder
- Justin Frances
- Juszynski Michal
- K\uf6lbel Tilo
- K\ufchme Tobias
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- Kall Torbj\uf6rn B
- Kallmayer Michael
- Kandyba Dmitry
- Kappadath Sreevalsan
- Kappelle Jaap L
- Karathanos Christos
- Karpenko Andrey
- Karram Tony
- Karvouniari Panagiota
- Kasemi Holta
- Kazan Viviane
- Keene Elizabeth
- Keese Michael
- Kelly Christine
- Kelsall Nicci
- Kenney Carol
- Kerner Arthur
- Keunen Rudolf W M
- Khanom Nyma
- Khuoge Christopher
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- Kimura Naoto
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- Kjellin Per
- Kl\uf6tzsch Christof
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- Kobeiter Hicham
- Komakha Boris B
- Kompara Ingrid
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- Kouvelos Georgios
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- Krohg-S\uf8rensen Kristen
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- Lardenoije Jan W
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- Lazaris Andreas
- le Conte Steffi
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- Lerut Philipe
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- Lindblad Bengt
- Lindert Ralph
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- Lindh Mats
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- Liu Chang-Wei
- Lo Rob H
- Loganathan Thayalini
- Lonsdale Robbie
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- Ludwig Stefan
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- M\ufcller Mandy
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- Mazzaccaro Daniela
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- McCaslin James
- McClelland Marie
- McCollum Charles N
- McConachie Norman
- McManus Jessica
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- Mele Maria Agnese
- Mendelow David
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- Menon Nisha
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- Milotic Franko
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- Mitchelson Kim
- Mitha Alim
- Modafferi Alfredo
- Moll Frans L
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- Montelione Nunzio
- Moore Dermot
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- Moratto Roberto
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- Myrcha Piotr
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- Neves Celso R B
- Nichol Ian
- Nikolsky Eugenia
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- Nome Terje
- Nor Azlisham M
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- Nyman Niklas
- O'Brien Imelda
- O'Brien Richard
- O'Connell Janice
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- Obach V\uedctor
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- Oliver Deborah
- Orrico Matteo
- Ostasz Wiktor
- Oszkinis Grzegorz
- Otto Dagmar
- P\ue4rsson H\ue5kan
- P\ufctz Volker
- Pacchioni Andrea
- Pacewski Bartosz
- Padovani Raymond
- Palasciano Giancarlo
- Palermo Sergio
- Palmer Debbie
- Palmiste Veronika
- Palombo Domenico
- Pan Hongchao
- Pan Hongchao
- Paolucci Aldo
- Parati Gianfranco
- Parlani Gian Battista
- Parr Noala
- Parry Andrew
- Parry Chris
- Patil Abhijeet
- Patti Francesco
- Pazdernyik Szil\ue1rd
- Peeters Andr\ue9
- Pegler Suzannah
- Pereira Antony
- Perfumo Maria Cecilia
- Peters Steven
- Petersen Bj\uf6rn
- Peto Richard
- Peto Richard
- Petrov Vesko
- Petrunic Mladen
- Pfeiffer Tomas
- Phair Alison
- Phiri Duke
- Pickworth Sandra
- Pieragalli Daniela
- Piffaretti Gabriele
- Pini Rodolfo
- Piorkowski Christopher
- Pizzirusso Rocco
- Plate Gunnar
- Pniewski Jaroslaw
- Polanski Jerzy
- Poletto Giorgio
- Polydorou Antonios
- Polydorou Victoria
- Pontes Neto Oct\ue1vio M
- Poorthuis Michiel
- Poskitt Keith
- Potter John
- Potts Caroline
- Pozzi Mucelli Fabio
- Pr\uedvara Mojm\uedr
- Prabakaran Raji O
- Praquin Barbara
- Presti Cal\uf3gero
- Proch\ue1zka V\ue1clav
- Proczka Robert
- Psacharopulo Daniele
- Psychogios Marios
- Puddu Giovanni Maria
- Puech-Le\ue3o Pedro
- Pukacki Fryderyk
- Pula Grazia
- Pulli Raffaele
- Punekar Shuja
- Pupo Guglielmo
- Quaretti Pietro
- Qvarfordt Peter
- R\uf3zanski Dorota
- R\uf6nnle Viola
- Raciborski Witold
- Radak \u110orde
- Rahi M Asad
- Rahimi Kazim
- Raj Sonia
- Ralli Styliani
- Ramadurai Gopi
- Ramsey-Williams Vicki
- Rantner Barbara
- Ratusinski Christoph-Maria
- Raudoniitis Aidas
- Reeps Christian
- Regina Guido
- Reif Michal
- Reijnen Michel
- Reimers Bernhard
- Remonda Luca
- Resch Tim
- Rhymes Christopher
- Riambau Vincent
- Richards Sue
- Richter Nadine
- Righini Paolo
- Roberts Aisling
- Robinson Graham
- Robson Rebecca
- Rocca Tiberio
- Rodgers Helen
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- Rogers Steven
- Ronchey Sonia
- Rossi Alessandro
- Rothwell Peter
- Roubec Martin
- Rountas Christos
- Rousas Nikolaos
- Rudenko Hannah
- Rusn\ue1k Franti\u161ek
- Ryckborst Karla J
- Rzezak Jaroslaw
- S\uf6hl Leander
- Saad Georges
- Sacc\ue0 Salvatore
- Sachs Tina
- Sagic Dragan
- Samis Greg
- San Rom\ue1n Luis
- Sandercock Peter
- Sargent Tracey
- Sattar Naweed
- Save Supriya
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- Sbarigia Enrico
- Scalise Filippo
- Scheinert Dierk
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- Schmidt Christine
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- Seriki Dare
- Serra Ribeiro Mauricio
- Setacci Carlo
- Setacci Francesco
- Sethuraman Sakthivel
- Seweryniak Piotr
- Shanik Gregor
- Shearman Cliff P
- Shimizu Hiroaki
- Siani Andrea
- Sichel Leonildo
- Siddegowda Shivaprasad
- Silani Vincenzo
- Silingardi Roberto
- Simonte Gioele
- Simpson David
- Singh-Ranger Ravi
- Sinha Devesh
- Sirignano Pasqualino
- Sitr\ue2ngulo Jr Cid J
- Ski\uf6ldebrand Claes
- Skjelland Mona
- Skoba Krisztina
- Skorski Maciej
- Sladojevic Milo\u161
- Slim Fiona
- Slowinski Maciej
- Slowinski Piotr
- Smeets Luuk
- Smith Eric E
- Smith Gemma
- Smith Sarah
- Smyth John V
- Soliman Gharieb Haytham
- Sonesson Bj\uf6rn
- Sorropago Giovanni
- Southam Alison
- Sova Jindrich
- Spanos Konstantinos
- Speziale Francesco
- Spinelli Francesco
- Staab Holger
- Staffa Robert
- Stani\u161ic Michal-Goran
- Staniszewski Ryszard
- Stansby Gerard
- Starodubtsev Vladimir
- Staszkiewicz Walerian
- Stefanis Leonidas
- Stegher Silvia
- Stella Andrea
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- Steuer Johnny
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- Stierli Peter
- Stilo Francesco
- Stippich Christoph
- Stirn Barbara
- Storck Martin
- Strozzi Francesco
- Stys Peter
- Subramaniam Suresh
- Sunman Wayne
- Sutherland Garnette R
- Szeberin Zolt\ue1n
- Szostek Mieczyslaw
- Takolander Rabbe
- Tanaskovic Slobodan
- Tate Margaret L
- Tavernarakis Antonios
- Teal Rachel
- Teixeira Louisa
- Tembl Ferrairo Jos\ue9 I
- Tenn\uf8e Bj\uf8rn
- Tervit Gareth
- Terzoudi Maria
- Tetickovic Erih
- Thomalla G\uf6tz
- Thomas Dafydd
- Thomas George
- Thompson Vicky
- Thomson Audrey
- Thomson George
- Thues Eddy
- Thyrion Federico Z
- Tinelli Giovanni
- Tinone Gisela
- Tissira Nadir
- Tochlin Sergey
- Tolva Valerio
- Tomczak Jolanta
- Tomic Ivan
- Tonello Diego
- Toni Danilo
- Toomsoo Toomas
- Toorop Raechel
- Torella Francesco
- Torsello Giovanni
- Tozzi Matteo
- Traenka Christopher
- Trastour Jean-Christophe
- Trimarchi Santi
- Troisi Nicola
- Tshomba Yamume
- Tsivgoulis Georgios
- Tsolaki Elpiniki
- Tully Lynda
- Turner Douglas
- Tusini Nicola
- Tyler Amanda
- Tysoe Sharon
- Ulrich Matthias
- V\uf6r\uf6s Erika
- Vacirca Andrea
- Vadikolias Kostas
- Valen\ue7a Falc\ue3o Martina
- Valentim Hugo
- van der Worp Bart H
- van Herzeele Isabelle
- van Overhagen Hendrik
- van Sterkenburg Steven
- Vasconcelos Leonor
- Vasdekis Spyros
- Vecchiati Enrico
- Venables Graham
- Verhelst Robert
- Vermassen Frank
- Veronesi Jessica
- Veroux Massimiliano
- Veroux Pierfrancesco
- Verzini Fabio
- Vetrivel Shanmugam
- Viazzo Andrea
- Vickers Alison
- Vidjak Vinko
- Vincenzoni Claudio
- Virgilio Carla
- Vison\ue0 Adriana
- Vlachovsk\ufd Robert
- Vojt\ued\u161ek Bohuslav
- Vonken Evert J
- Vos Floris
- Wagner Benjamin
- Waldron Joanne
- Wales Lucy
- Wallis Carol
- Warvsten Margareta
- Watling Dave
- Watson Tim
- Wealleans Vera
- Webb Tom
- Weiss Norbert
- Welch Mark
- Welsh Sarah
- Wennrich Michael
- Werner Martin
- Werth Sebastian
- Wever Jan J
- White Richard
- Whyman Mark
- Wiegert Martina M
- Willet Monique
- Williams Akintunde
- Williams Lucy
- Wilson Lesley
- Wilson Toni
- Windebank Steve
- Winzer Simon
- Wolfe John
- Wolff Thomas
- Wolowczyk Leszek
- Wong John H
- Wyatt Michael
- Young Alan
- Young Gavin
- Yperzeele Laetitia
- Yusta Izquierdo Antonio
- Zaefferer Patricio
- Zalunardo Beniamino
- Zanow J\ufcrgen
- Zdanowski Zbigniew
- Zelen\ue1k Kamil
- Zherdev Nikolay N
- Ziani Barbara
- Zielinski Maciej
- Zimmel L
- Zimmermann Alexander
- Zini Andrea
- Zuromskis Tadas
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Background: Among asymptomatic patients with severe carotid artery stenosis but no recent stroke or transient cerebral ischaemia, either carotid artery stenting (CAS) or carotid endarterectomy (CEA) can restore patency and reduce long-term stroke risks. However, from recent national registry data, each option causes about 1% procedural risk of disabling stroke or death. Comparison of their long-term protective effects requires large-scale randomised evidence.
Methods: ACST-2 is an international multicentre randomised trial of CAS versus CEA among asymptomatic patients with severe stenosis thought to require intervention, interpreted with all other relevant trials. Patients were eligible if they had severe unilateral or bilateral carotid artery stenosis and both doctor and patient agreed that a carotid procedure should be undertaken, but they were substantially uncertain which one to choose. Patients were randomly allocated to CAS or CEA and followed up at 1 month and then annually, for a mean 5 years. Procedural events were those within 30 days of the intervention. Intention-to-treat analyses are provided. Analyses including procedural hazards use tabular methods. Analyses and meta-analyses of non-procedural strokes use Kaplan-Meier and log-rank methods. The trial is registered with the ISRCTN registry, ISRCTN21144362.
Findings: Between Jan 15, 2008, and Dec 31, 2020, 3625 patients in 130 centres were randomly allocated, 1811 to CAS and 1814 to CEA, with good compliance, good medical therapy and a mean 5 years of follow-up. Overall, 1% had disabling stroke or death procedurally (15 allocated to CAS and 18 to CEA) and 2% had non-disabling procedural stroke (48 allocated to CAS and 29 to CEA). Kaplan-Meier estimates of 5-year non-procedural stroke were 2·5% in each group for fatal or disabling stroke, and 5·3% with CAS versus 4·5% with CEA for any stroke (rate ratio [RR] 1·16, 95% CI 0·86-1·57; p=0·33). Combining RRs for any non-procedural stroke in all CAS versus CEA trials, the RR was similar in symptomatic and asymptomatic patients (overall RR 1·11, 95% CI 0·91-1·32; p=0·21).
Interpretation: Serious complications are similarly uncommon after competent CAS and CEA, and the long-term effects of these two carotid artery procedures on fatal or disabling stroke are comparable
Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE): a prospective European multicentre observational study
- Author
- 6\ue7men Elvan
- 6zcengiz Dilek
- \u17durek Ji\u159\ued
- Abbott Joy
- Absalom Anthony R.
- Adil Sadia
- Aehling Carolin
- Afshari Arash
- Agapiti Cristina
- Ahmad Nargis
- Akin Mine
- Alders David
- Allison Celia
- Amory Catherine
- Arbona Celia
- Armstrong James
- Art\ue9s David
- Astuto Marinella
- Attanasi Elena
- Audren Noemie
- Auli Cristina
- Ayanoglu Hilmi
- Azizoglu Mustafa
- Azman Josip
- B\uf6gli Yann
- Badelt Gregor
- Badeti Rodica
- Baehner Torsten
- Bali Evangelia
- Baranowski Artur
- Baris Sibel
- Barlow Victoria
- Barnes David
- Bartkowska-Sniatkowska Alicja
- Barzdina Arta
- Baujard Catherine
- Bauters Annemie
- Becke Karin
- Bell Graham
- Bell Sarah
- Bellon Myriam
- Bengt Sporre
- Bennis Mehdi
- Beno\ueet Plichon
- Berger Jelena
- Berghmans Johan
- Bergsma Margot
- Bert Dina
- Beukers Anne M.
- Bew Stephanie
- Bille Anders Bastholm
- Bilotta Federico
- Birbi\ue7er Handan
- Blain Stuart
- Blevin Andrew
- Bodlani Carol
- Boer Christa
- Boerke Wenche B.
- Bomont Rob
- Bonfiglio Rachele
- Bordes Maryline
- Bottazzi Giulia
- Breschan Christian
- Brigitte Leva
- Brooks Peter
- Bruelisauer Thomas
- Brunner Lena
- Budic Ivana
- Buhre Wolfgang
- Buitenhuis Marielle
- Butkovi\u107 Diana
- Cabanov\ue1 Barbora
- Cajkov\ue1 Petra
- Calderini Edoardo
- Camporesi Anna
- Caramelli Fabio
- Casey Michelle
- Cassar Carmel
- Castellheim Albert
- Casutt Mattias
- Cebri\ue1n Jes\ufas
- Chamizo Alicia
- Childs Sophie
- Chloropoulou Pelagia
- Cindea Iulia
- Cinnella Gilda
- Cohausz Ruth
- Colantonio Laura Brigitta
- Constant Isabelle
- Cooper Natalie
- Cortegiani Andrea
- Cotoia Antonella
- Couchepin Caroline
- Coustets Bernard
- Crate Lindsay
- Csillag Judit
- D\uf6renberg Rainer
- Dadure Christophe
- Dahmani Souhayl
- Daniels Lisa
- De Baerdemaeker Luc
- De Boer Rients
- de Graaff Jurgen
- De Hert Stefan
- De la Arena Pablo
- de la Bri\ue8re Fran\ue7ois
- De Liefde Inge
- De Lorenzo Brita
- De Ruiter Joke
- De Silva Sam
- Del Rey de Diego Pilar
- Depret-Donatien Veronique
- Dertinger Jurgen
- Descarpentries Thomas
- Diers Anja
- Dincer Pelin Corman
- Disma Nicola
- Disma Nicola
- Dix Philippa
- Dmytriiev Dmytro
- Dobby Nadine
- Dolci Mirko
- Doruk Nurcan
- Dra\u161kovi\u107 Biljana
- Drage Inger Marie
- Druot Emilie
- Dupont Herv\ue9
- Edelman Isole
- Eger Johanes
- Eggemann Isabel
- Eisner Christoph
- Ekiz Nil
- Ellekvist Marguerite
- Ellerkmann Richard
- Emal Dina
- Emery John
- Engelhardt Thomas
- Erb Thomas
- Erdoes Gabor
- Erdost Hale Aksu
- Escrib\ue1 Francisco
- Esteves Catarina Cruz
- Fabre Fanny
- Favarato Moreno
- Fesseau Rose
- Finamore Simona Anna
- Fischer Thomas
- Flinspach Armin
- Frasacco Giulia
- Frelich Michal
- Frykholm Peter
- G\ue1l J\ue1nos
- G\uf6bl Gergely
- Galante Dario
- Gallagher Sarah
- Gandhi Monica
- Garc\ueda Mart\uednez Irene
- Garcia Maria
- Garini Eleana
- Garra Rossella
- Ghamari Shahab
- Gilpin Dan
- Giombini Mariangela
- Godart Juliette
- Goddard Kevin
- Goeters Christiane
- Gonz\ue1lez Serrano Cristina
- Goonasekera Chulananda
- Gordeva Elena
- Grasso Chiara
- Grazzini Maurizia
- Grzeskowiak Malgorzata
- Guddo Anna
- Gurita Adriana
- H\uf6lzle Martin
- Habre Walid
- Habre Walid
- Hamonic Yann
- Hansen Tom
- Hanula Miloslav
- Hare Alison
- Harju Jarkko
- Harte Sinead
- Hatipo\u11flu Zehra
- Hauser Bal\ue1zs
- Haussmann Sascha
- Hendriks Mark
- Hertz Laurent
- Heschl Stefan
- Hochmuth Karin
- Hoehne Claudia
- Hurni Thomas
- Ilic Jordanka
- Ilie Luminita
- Ilmoja Mari-Liis
- Iordanidou Despoina
- Isern Erik Ramon
- Izquierdo Alberto
- J\uf6hr Martin
- Jackson Mandy
- Jacqmarcq Olivier
- Jakubowska Karina
- James Kathryn
- Janjatovic Darja
- Jelting Yvonne
- Jinks Stephanie
- Jonckheer Karin
- Julia Dowell
- Julien-Marsollier Florence
- Juzwa-Sobieraj Magdalena
- Kahn David
- Kaiser Heiko
- Kallio Kariantti
- Karafotia Afroditi
- Katalin Vir\ue1g
- Kaufmann Jost
- Kaufmann Jost
- Kaya Guner
- Keilig Susanna
- Kendigelen Pinar
- Kerovec Sori\u107 Ivana
- Keskin Gulsen
- Khalil Eliane
- Kikas Reet
- King Hannah
- King Stephanie
- Klages Matthias
- Knezevic Mirjana
- Knoppov\ue1 Lenka
- Kohn Ivan
- Kokki Hannu
- Kokki Merja
- Kokkonen Miia
- Koller Bernhard
- Kosik Nandor
- Kotzeva Svetlana
- Kralik Sandra
- Kranke Peter
- Kretz Franz-Josef
- Krishnan Prakash
- Kroess Ruth
- Kuchi Sridevi
- Kuppers Beate
- Kvarnstr\uf6m Ann
- L\uf3pez Silvia
- L\uf6ffler Michaela
- Laffargue Anne
- Lako Sandra
- Lapage Koen
- Laschat Michael
- Lauweryns Julie
- Leal Teresa
- Legrand Aur\ue9lien
- Leister Nicolas
- Lejus-Bourdeau Caroline
- Lenares Elena
- Leone Roberto
- Lerro Daniela
- Lesage Anne
- Lewandowska Dorota
- Likar Rudolf
- Lindau Simone
- Lindestam Ulf
- Locatelli Bruno Guido
- Ludot Hugues
- Lukosiene Laura
- M\ue9ndez Dolores
- Machotta Andreas
- Maffioletti Micol
- Magne C\ue9cile
- Mal\ue4r Anna-Ursina
- Malarkkan Nalini
- Malisiova Anna
- Mameli Leila
- Mammi Panagoula
- Mandras Ana
- Manner Tuula
- Manrique Mu\uf1oz Susana
- Mar\ue1czi Veronika
- Maraulaite Irena
- Marchon Mathias
- Marcucci Carine
- Marjanovic Vesna
- Marki\u107 Ana
- Markic Josko
- Mart\uednez Garc\ueda Ernesto
- Martin Paul
- Masip Nuria
- Mattioli Girolamo
- Mauch Jacqueline
- McKee Lesley
- Meehan Emma
- Meier Sascha
- Mele Sara
- Menzel Christoph
- Messerer Brigitte
- Messroghli Leila
- Micalizzi Camilla
- Michelet Daphne
- Mierzewska-Schmidt Magdalena
- Mifsud Stephanie
- Milojevic Irina
- Minardi Carmelo
- Miskovic Alice
- Mission Jean-Paul
- Mixa Vladim\uedr
- Mocioiu Gabriel
- Mondardini Maria Cristina
- Montaguti Alessia
- Montferrer Estruch Nuria
- Moor Reet
- Morariu Mihai
- Moscarelli Alessandra
- Mueller Thomas
- Munteanu Valentin
- Najafi Nadia
- Nawoor Zeenat
- Neba Gerald Rogan
- Neumann Claudia
- Ngan Esther
- Nicholson Katy
- Norman Joanne
- Nouette Gaulain Karine
- Ntritsou Vagia
- Numan Sandra
- Ny\uedri Emese
- O\u2019Hare Brendan
- Oana Loredana
- Ochsenreiter Miriam
- Oeinck Karin
- Olguner \uc7imen
- Oppenrieder Karin
- Orliaguet Gilles
- Oshan Vimmi
- P\ue9rez Pardo Osvaldo
- Pachter David
- Pad Rebecca
- Pandurov Marina
- Papagiannopoulou Pinelopi
- Parashchanka Aliaksandra
- Patuleia Maria Domingas
- Peleteiro Ana
- Perry Chris
- Petr\uf3czy Andr\ue1s
- Petrov Ivana
- Petry L\ue9a
- Picardo Sergio
- Pichon Isabelle
- Pierre Harlet
- Pieters Barbe
- Pina Pedro
- Pinho S\uedlvia
- Pino Gema
- Pinzoni Francesca
- Pirat Philippe
- Pirotte Thierry
- Pirtov\u161ek \u160tupnik \u160pela
- Pistorio Angela
- Platzer Manuela
- Polyzoi Artemis
- Pont\ue9n Emma
- Porro Giuliana Anna
- Poves-\uc1lvarez Rodrigo
- Pregardien Caroline
- Prisca Feijten
- Przemyslaw Pomianek
- Pupacic Daniela
- Puric Racic Selena
- Quinney Michelle
- Rados Zdenka
- Razlevice Ilona
- Reil Anita
- Reimer Petr
- Reinhard Jarl
- Reponen Elisa
- Richter Daniel
- Richter Sebastian
- Riva Thomas
- Riva Thomas
- Robertson Andrew
- Ros Lilica
- Rosada-Kurasi\u144ska Jowita
- Ross Mark
- Rossetti Emanuele
- Roulleau Philippe
- Rubio Paloma
- S\uf6hle Martin
- Sabau Lucie
- Sabourdin Nada
- Sagun Asl\u131
- Salgado Helena
- Sammartino Maria
- Sandstr\uf6m Kerstin
- Santos Maria Jo\ue3o
- Sapi Erzsebet
- Sarah Herbineaux
- Sawicki Piotr
- Sbaraglia Fabio
- Scalia Catenacci Stefano
- Scalisi Rita
- Sch\ue4fer Melanie
- Sch\uf6ler Michael
- Schafrat Eva
- Scheffczik Jutta
- Scheffer Gert-Jan
- Schmitz Bernd
- Schnur Janos
- Schorer Clemens
- Schreiber Jan
- Scoones Gail
- Scordo Lucia
- Scott Carmen
- Sedl\ue1\u10dkov\ue1 Yvona
- Seiler Stefan
- Semjen Fran\ue7ois
- Senayli Yesim
- Serrano Silvia
- Shah Khairi
- Sierra Biddle Natalia
- Simic Dusica
- Simic Irena
- Smith Paul
- Soares Maria
- Sogbodjor L. Amaki
- Sola Chrystelle
- Sonzogni Valter
- Staals Lonneke
- Staiti Giuseppe
- Stankovic Nikola
- Stensrud Kristoffer
- Stevens France
- Stevens Markus
- Stevens Paul
- Stevic Marija
- Stichlberger Martina
- Straume Zane
- Su\ue1rez Casta\uf1o Ceferina
- Suarez Comas Montserrat
- Suica Maja
- Sunderland Robin
- Suominen Pertti
- Suvanto Sami
- Sz\ue9kely Edgar
- T\uf6vish\ue1zi Gyula
- Tabacaru Radu
- Tan Li-En
- Terboven Tom
- Tesoro Simonetta
- Tielens Luc
- Tomas Jeremy
- Tormo de las Heras Carolina
- Trante Irina
- Trieschmann Uwe
- Troncoso Montero Pablo
- Tsiotou Adelais
- Tutuncu Ayse \uc7i\u11fdem
- Uhrig Lynn
- Ulrici Johanna
- Umuroglu Tumay
- Urban-Lechowicz Magdalena
- Urbanec Ren\ue9
- Urbina Benjamin
- V\ue4h\ue4talo Raisa
- V\ue4li Merle
- Van der Knijff-van Dortmont Anouk
- Van Limmen Jurgen
- Van Zaane Bas
- Vasiljevic Sladjana
- Vav\u159ina Martin
- Veldhuizen Marianne
- Vermeulen Petronella Mari
- Verzelloni Alessandra
- Veyckemans Francis
- Vezzoli Cesare
- Vieri Jenni
- Vilardell Ort\uedz Elena
- Villalobos Rico Mar\ueda Isabel
- Virag Katalin
- Vittinghof Maria
- Vittori Alessandro
- Voet-Lindner Marieke
- Volkers Martin
- Vulicevic Irena
- Vundelinckx Joris
- Vutskits Laszlo
- Walker Ellie
- Walker Suellen
- Wappler Frank
- Waring Lynne
- Weigand Markus
- Weiterer Sebastian
- Weyland Andreas
- Wilbs Markus
- Wolfe Barry Juliet
- Wolfler Andrea
- Worrall Mark
- Wyffels Piet
- Y\ufccetepe Sirin
- Zacharowski Kai
- Zadra Nicola
- Zanaboni Clelia
- Zang Aur\ue9lien
- Zielinska Marzena
- Zl\ue1malov\ue1 (ne\ue9 Kv\u11bto\u148ov\ue1) Alena
- Zundane Anda
- Zweers Tjerk
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
International audienceBackground: Neonates and infants are susceptible to hypoxaemia in the perioperative period. The aim of this study was to analyse interventions related to anaesthesia tracheal intubations in this European cohort and identify their clinical consequences.Methods: We performed a secondary analysis of tracheal intubations of the European multicentre observational trial (NEonate and Children audiT of Anaesthesia pRactice IN Europe [NECTARINE]) in neonates and small infants with difficult tracheal intubation. The primary endpoint was the incidence of difficult intubation and the related complications. The secondary endpoints were the risk factors for severe hypoxaemia attributed to difficult airway management, and 30 and 90 day outcomes.Results: Tracheal intubation was planned in 4683 procedures. Difficult tracheal intubation, defined as two failed attempts of direct laryngoscopy, occurred in 266 children (271 procedures) with an incidence (95% confidence interval [CI]) of 5.8% (95% CI, 5.1-6.5). Bradycardia occurred in 8% of the cases with difficult intubation, whereas a significant decrease in oxygen saturation (SpO2<90% for 60 s) was reported in 40%. No associated risk factors could be identified among co-morbidities, surgical, or anaesthesia management. Using propensity scoring to adjust for confounders, difficult anaesthesia tracheal intubation did not lead to an increase in 30 and 90 day morbidity or mortality.Conclusions: The results of the present study demonstrate a high incidence of difficult tracheal intubation in children less than 60 weeks post-conceptual age commonly resulting in severe hypoxaemia. Reassuringly, the morbidity and mortality at 30 and 90 days was not increased by the occurrence of a difficult intubation event