13 research outputs found
A praeeclampsia pszichoszociális vonatkozásai
Distress conditions during pregnancy may contribute to the development of preeclampsia by altering functions of the neuroendocrine and immune systems, e.g. activation of the hypothalamic-pituitary-adrenal axis and increase in plasma proinflammatory cytokines. Preeclampsia may also precipitate mental health problems due to long-term hospitalization or unpredictable and uncontrollable events such as preterm labor and newborn complications. Besides, preeclampsia may induce persistent neurocognitive complaints with a negative impact on patients' quality of life. As growing evidence indicates that poor maternal mental health has an adverse effect on pregnancy outcome and fetal development, psychosocial interventions may be beneficial for women with preeclampsia. Orv. Hetil., 2015, 156(50), 2028-2034
Városi zöldfelĂĽletek dĂsznövĂ©nyeihez rĂ©gebben Ă©s Ăşjonnan alkalmazkodott, nem szĂpĂłkás rovarfajok illat-hĂrközlĂ©sĂ©nek feltárása = Revealing odour communications of some native and invasive non-sucking insects, adapted to ornamental plants in urban green areas
A városi zöldterĂĽletek egy invazĂv kártevĹ‘je, a lepĂ©nyfa-gubacsszĂşnyog (Dasineura gleditchiae, Dipt., Cecidomyiidae) Ă©s egy Ĺ‘shonos tölgyaknázĂł moly (Tischeria ekebladella, Lep., Tischeriidae) szexferomonját azonosĂtottuk, hogy merĹ‘ben Ăşj kommunikáciĂłs csatornákat tárjunk fel, Ă©s hogy az elĹ‘rejelzĂ©shez csapdákat lehessen kifejleszteni. Az áttörĂ©st mindkĂ©t esetben a bioszenzoros gázkromatográffal Ă©rtĂĽk el (GC-EAD), mĂg a szerkezetazonosĂtást Ă©s az izomĂ©r- / enanciomĂ©r-specifikus szintĂ©zist nemzetközi egyĂĽttműködĂ©sben vĂ©geztĂĽk (NRI, UK; Univ. Hamburg, D). A gubacsszĂşnyog feromonja (2R,8Z)-2-acetoxy-8-heptadekánnak bizonyult. Ez Ăşj feromonszerkezetet kĂ©pvisel. A csapdák rendkĂvĂĽl jĂłnak bizonyultak (Budapest). SegĂtsĂ©gĂĽkkel elsĹ‘kĂ©nt sikerĂĽlt a terjedĹ‘ben lĂ©vĹ‘ kártevĹ‘ felbukkanását Ă©szlelni DĂ©l-SvĂ©dországban. A csapdák már megrendelhetĹ‘k intĂ©zetĂĽnk Alkalmazott KĂ©miai Ă–kolĂłgiai OsztályátĂłl (Csalomon®). A tölgyaknázĂłmoly feromonja (3Z,6Z,9Z,19Z)-tricosa-3,6,9,-19-tetraĂ©n, ami nemcsak Ăşj feromon, de a termĂ©szetes anyagok körĂ©ben is Ăşjdonság, Ă©s egyben az elsĹ‘ azonosĂtott feromon ebben a családban. EredmĂ©nyeink azt jelzik, hogy a poliĂ©nek elĹ‘ször az Ĺ‘si Tischeriidae családban jelentek meg a lepkĂ©k evolĂşciĂłja során. Gyakorlati vonatkozás: a tetraĂ©nnel csalĂ©tkezett feromoncsapda alkalmazhatĂł ennek a kártevĹ‘nek a monitorozására. | We have identified the sex pheromone of an invasive gall midge Dasineura gleditchiae (Dipt., Cecidomyiidae), as well as of a native leaf miner Tischeria ekebladella (Lep., Tischeriidae), pests of trees in urban areas, in order to reveal new chemical communication systems and, as practical relevance, to develop new pheromone traps for monitoring. The break-through was achieved in both cases by pinpointing the active compounds by gas chromatography coupled to an antennal detector (GC-EAD), while structure elucidation (GC-MS), followed by isomer / enantiomer-selective syntheses were completed in international cooperation (NRI, UK; Univ. Hamburg, D). The pheromone of the gall midge was identified as (2R,8Z)-2-acetoxy-8-heptadecane. This is a new structure for insect pheromones. Newly developed traps proved to be highly attractive in Budapest. With their help, this expansive gall midge was first detected in Southern Sweden. Traps have already been commercialized by the Dept. Applied Chemical Ecology of our institute (Csalomon®). (3Z,6Z,9Z,19Z)-tricosa-3,6,9,-19-tetraene was identified as the pheromone of the leaf miner. This compound represents not only just a new pheromone structure, but also a new natural product, and also the first pheromone identified in this family. As for evolution of pheromones of Lepidoptera, our finding indicates that polienic pheromones were evolved first time in this ancient family. As for practical relevance, the tetrane may serve as bait for traps
Application of synthetic solid culture medium to improve the detection of antimicrobial drug residues in foodstuffs (secondary publication)
Summary
Background: Recent laboratory tests being in use in Europe to detect antibiotic resi dues in human food are either based on the so called Four Plate Test (UE4pt) employ ing Bacillus subtilis as test organism, or on direct chemical test procedures. The Four
Plate Test is widely utilized as a scanning method due to simplicity and low cost,
however, sensitivity of the chemical detection methods has been about a magnitude
higher.
Objectives: Purpose of this study was to increase the sensitivity of the biological
testing, using B. subtilis as test organism, through restricting nitrogen and carbon
supply in the culture media. It was hoped that an effective, portable test tool with low
lab technology requirement could be developed.
Materials and Methods: Growth and antibiotic sensitivity characteristics of B. sub tilis were compared using Mueller-Hinton Agar and our two limited nutrient supply
semisolid media. Ammonium sulphate was combined either with glucose or sodium
pyruvate in buffered agar. Each composed medium was tested at both pH 6.0 and
pH 8.0. Growth inhibition was measured around commercial antibiotic resitance test
disks containing 21 respective antibiotics.
Results and Discussion: The medium based on ammonium sulphate and sodium
pyruvate, pH 6.0 proved to be most suitable as a replacement of Mueller Hinton
Agar in the Four Plate Test. Growth inhibition, indicating sensitivity, improved by 1.4
to 4.0-fold, depending on the antibiotic. This allows the detection of levels up to a
magnitude smaller amount of antibiotics than the original Four Plate Test. Unlike
Mueeler Hinton Agar, our artificial medium does not contain any accidental inhibitor
substances. Morover, the medium is superselective for B. subtilis, cheap and highly
consistent in composition, as well as results
Medencegyűrű-sĂ©rĂĽlĂ©sek műtĂ©ti rögzĂtĂ©sĂ©nek vĂ©geselemes modellezĂ©se
A vertikálisan Ă©s rotáciĂłban is instabil C tĂpusĂş medencegyĂ»rĂ»-sĂ©rĂĽlĂ©sek rögzĂtĂ©sĂ©re használt kĂĽlönbözõ lemezes rögzĂtĂ©si technikák stabilitási vizsgálata az általunk kidolgozott vĂ©geselemes medencemodellen. KĂ©t lábon állás mellett C tĂpusĂş medencegyĂ»rĂ»-sĂ©rĂĽlĂ©st hoztunk lĂ©tre Ăşgy, hogy Denis I., illetve Denis II. keresztcsont (sacrum) törĂ©st Ă©s a szemĂ©remcsonti ĂzĂĽlet szakadását (symphyseolysist) modelleztĂĽnk. A symphyseolysist 4 lyukas rekonstrukciĂłslemezzel, a Denis I. sacrumtörĂ©st 2 db 2 lyukas rekonstukciĂłs lemezzel stabilizáltuk a kismedence felõl (ventralisan), majd az általunk használt transsacralisan, hátulrĂłl (dorsalisan) felhelyezett keskeny, illetve szĂ©les DC-lemezzel. A Denis II. sacrumtörĂ©st ventral felõl ugyancsak2 db 2 lyukas rekonsrukciĂłs lemezzel fixáltuk, majd dorsal felõl KFI-H-lemezes rögzĂtĂ©st modelleztĂĽnk. A vĂ©geselemes modellezĂ©s ALGOR programmal törtĂ©nt. A medencĂ©t alkotĂł csontok mellett az ĂzĂĽleteket Ă©s a mechanikai szempontbĂłl jelentõs szalagokat is modelleztĂĽk. A modell validálása megtörtĂ©nt, párhuzamosan vĂ©gzett hullai csont-szalagos preparátumokon vĂ©gzett mĂ©rĂ©si eredmĂ©nyekkel. A törĂ©si rĂ©s kĂ©t oldala közötti elmozdulást, valamint a rögzĂtõfĂ©mekben Ă©s a környezõ csontokban fellĂ©põ feszĂĽltsĂ©geket mĂ©rtĂĽk. A transsacralis lemezes synthesis mellett nagyobb elmozdulások mĂ©rhetõk, mint direkt lemezes rögzĂtĂ©s esetĂ©n. A KFIH-lemezekkel vĂ©gzett mĂ»tĂ©t stabilitása a direkt lemezes Ă©s a transsacralis lemezes synthesis stabilitása között van. Az eredmĂ©nyek korrelálnak a párhuzamosan elvĂ©gzett csont-szalagos hullai medencepreparátumokon vĂ©gzett mĂ©rĂ©sek eredmĂ©nyeivel. A vĂ©geselemes modell alkalmas a fentleĂrt sĂ©rĂĽlĂ©seket rögzĂtõ synthesisformák összehasonlĂtására. Mivel a cadaver-preparátumokon vĂ©gzett vizsgálatok számos nehĂ©zsĂ©gbe ĂĽtköznek, a modell használatának lĂ©tjogosultságavitathatatlan.A vertikálisan Ă©s rotáciĂłban is instabil C tĂpusĂş medencegyĂ»rĂ»-sĂ©rĂĽlĂ©sek rögzĂtĂ©sĂ©re használt kĂĽlönbözõ lemezes rögzĂtĂ©si technikák stabilitási vizsgálata az általunk kidolgozott vĂ©geselemes medencemodellen. KĂ©t lábon állás mellett C tĂpusĂş medencegyĂ»rĂ»-sĂ©rĂĽlĂ©st hoztunk lĂ©tre Ăşgy, hogy Denis I., illetve Denis II. keresztcsont (sacrum) törĂ©st Ă©s a szemĂ©remcsonti ĂzĂĽlet szakadását (symphyseolysist) modelleztĂĽnk. A symphyseolysist 4 lyukas rekonstrukciĂłs lemezzel, a Denis I. sacrumtörĂ©st 2 db 2 lyukas rekonstukciĂłs lemezzel stabilizáltuk a kismedence felõl (ventralisan), majd az általunk használt transsacralisan, hátulrĂłl (dorsalisan) felhelyezett keskeny, illetve szĂ©les DC-lemezzel. A Denis II. sacrumtörĂ©st ventral felõl ugyancsak 2 db 2 lyukas rekonsrukciĂłs lemezzel fixáltuk, majd dorsal felõl KFI-H-lemezes rögzĂtĂ©st modelleztĂĽnk. A vĂ©geselemes modellezĂ©s ALGOR programmal törtĂ©nt. A medencĂ©t alkotĂł csontok mellett az ĂzĂĽleteket Ă©s a mechanikai szempontbĂłl jelentõs szalagokat is modelleztĂĽk. A modell validálása megtörtĂ©nt, párhuzamosan vĂ©gzett hullai csont-szalagos preparátumokon vĂ©gzett mĂ©rĂ©si eredmĂ©nyekkel. A törĂ©si rĂ©s kĂ©t oldala közötti elmozdulást, valamint a rögzĂtõ fĂ©mekben Ă©s a környezõ csontokban fellĂ©põ feszĂĽltsĂ©geket mĂ©rtĂĽk. A transsacralis lemezes synthesis mellett nagyobb elmozdulások mĂ©rhetõk, mint direkt lemezes rögzĂtĂ©s esetĂ©n. A KFIH-lemezekkel vĂ©gzett mĂ»tĂ©t stabilitása a direkt lemezes Ă©s a transsacralis lemezes synthesis stabilitása között van. Az eredmĂ©nyek korrelálnak a párhuzamosan elvĂ©gzett csont-szalagos hullai medencepreparátumokon vĂ©gzett mĂ©rĂ©sek eredmĂ©nyeivel. A vĂ©geselemes modell alkalmas a fent leĂrt sĂ©rĂĽlĂ©seket rögzĂtõ synthesisformák összehasonlĂtására. Mivel a cadaver-preparátumokon vĂ©gzett vizsgálatok számos nehĂ©zsĂ©gbe ĂĽtköznek, a modell használatának lĂ©tjogosultsága vitathatatlan. DOI: 10.17489/biohun/2008/1/3
Relevance of anxiety in the perinatal period: prospective study in a Hungarian sample
There is increasing evidence that anxiety occurs frequently during pregnancy and can be one of the most important risk factors and predictors of postpartum depression (PPD). The aim of our study was to investigate whether antenatal anxiety is an independent predictor of PPD. We used the data of 476 women enrolled in a prospective study in a single maternity unit. The first assessment was conducted between 22 and 40 weeks gestation and a second time 8-12 months postpartum. Symptoms were measured using the Edinburgh Postnatal Depression Scale (EPDS) and the State Trait Anxiety Inventory (STAI). Based on our results, antenatal anxiety measured by a subscale of EPDS has predicted better PPD than the antenatal depressive subscale. However, the most relevant predictor of PPD might be the trait anxiety level of a women measured by STAI Trait Scale, whereas a cutoff value of 38 was identified to indicate higher risk of PPD
Relevance of anxiety in the perinatal period: prospective study in a Hungarian sample
There is increasing evidence that anxiety occurs frequently during pregnancy and can be one of the most important risk factors and predictors of postpartum depression (PPD). The aim of our study was to investigate whether antenatal anxiety is an independent predictor of PPD. We used the data of 476 women enrolled in a prospective study in a single maternity unit. The first assessment was conducted between 22 and 40 weeks gestation and a second time 8–12 months postpartum. Symptoms were measured using the Edinburgh Postnatal Depression Scale (EPDS) and the State Trait Anxiety Inventory (STAI). Based on our results, antenatal anxiety measured by a subscale of EPDS has predicted better PPD than the antenatal depressive subscale. However, the most relevant predictor of PPD might be the trait anxiety level of a women measured by STAI Trait Scale, whereas a cutoff value of 38 was identified to indicate higher risk of PPD