The formation of carbonaceous layer from ethylene over various transition metal catalysts – an FT-IR study

The ethylene-derived carbonaceous overlayers were studied over silica-supported Pt, Pd, Rh and Cu catalysts by FT-IR spectroscopy under desorption conditions. As a general feature it was observed over all catalysts that upon increasing the desorption temperature the overlayer gradually became poor in hydrogen. The structure of the overlayers was similar over the silica-supported Pt, Pd and Rh. On increasing the reaction temperature the σ-adsorbed half-hydrogenated species are transformed to adsorbed ethylidyne. On the Cu catalyst prepared with ion exchange a similar picture emerged, while on those prepared with precipitation ethylidyne soon became the predominant species. Hydrogen swept off the carbonaceous species from the transition metals, however, copper retained large portions of it

Egy új roncsolásmentes geokémiai módszer - a PGAA - archeometriai alkalmazásai = Applications of a New Non-destructive Geochemical Method (PGAA) in Archaeometry

Kőeszközök közül obszidián, radiolarit, flint, limnokvarcit pattintott-, valamint bazalt, dolerit, zöldpala-kontakt metabázit csiszolt eszközök és szerszámkövek nyersanyageredet-vizsgálatát végeztük elsősorban roncsolásmentes PGAA-val. Horvát és bosnyák ásatásokról származó obszidián régészeti leletekről megállapítottuk, hogy nyersanyaguk mediterrán (Lipari), ill. kárpáti (Tokaj-hg.) eredetű. A két nyersanyagellátási terület határát Bosznia középső részén valószínűsítjük. Elsőként szolgáltattunk analitikai alapadatokat radiolarit, és más kova kőeszközökről. Megmutattuk, hogy az ÉNy-horvátországi kovás nyersanyagok gyenge minőségűek, feltehetően csupán helyi eszközkészítésre használták. Vizsgáltuk a Magyar Nemzeti Múzeum Ebenhöch gyűjteményét és a gorzsai késő neolit lelőhely csiszolt kőeszköz leleteit. Alap adatbázist hoztunk létre a magyarországi csiszolt kőeszközök és néhány potenciális nyersanyag PGAA mérési eredményeiből. Pontosítottuk a felsőcsatári és a cseh-masszívumbeli zöldpala-metabázit kőzettípusok elkülöníthetőségét, jó eredményeket értünk el a bazalt-dolerit-alkáli dolerit elkülönítésében. A PGAA mérések alapján számos finomszemcsés kőeszköz kőzettípusát tisztáztuk. A Bükki kultúra kerámiáiról geokémiai adatokkal (XRF, kiegészítő PGAA) bizonyítottuk, hogy a jellegzetes finomkerámia típus nem a nyersanyag kémiai-ásványos összetétele, hanem fizikai-technológiai tulajdonságai miatt egyedi. Létrehoztunk egy régészeti kerámia adatbázist (CERAMIS). | We performed provenance research of chipped stone tools (obsidian, radiolarite, flint, etc.), as well as of polished stone tools (basalt, greenschist, etc) and other stone utensils – with non-destructive PGAA. We established a differentiation between the Mediterranean (Lipari) and Carpathian (Tokaj) origin obsidian archaeological objects, found in Croatia and Bosnia. A border of the two supply areas supposed to exist in central Bosnia. The first basic analytical data of radiolarite and other silex stone tools were provided. It was shown that the poor quality North-western Croatian silex was used probably for local production. Polished stone tools from Ebenhöch Collection of the Hungarian National Museum and the stone assemblage of the late Neolithic Gorzsa site were also studied. A PGAA database of Hungarian origin polished stone objects and their raw materials was set. A more accurate distinction between greenschist-metabasite from Felsőcsatár and the Bohemian Massif was done. Based on PGAA results, typology of some fine-grained stone tools was cleared up. We also investigated Neolithic ceramics from Northern Hungary (Bükk culture). We proved with geochemical experimental data (XRF and PGAA) that the typical finegrain ceramics are distinctive in their physical-technological properties, rather than in their raw material composition. Finally, a database of archaeological ceramics (CERAMIS) was created

A verseny szerepe és felfogása Magyarországon = The role and appreciation of competition in Hungary

A kutatás során több pilléren állva tanulmányoztuk a verseny és a versenypolitika szerepét az EU tag Magyarországon. Megvizsgáltuk a ma is ható főbb versenyelméleti iskolákat, s oda jutottunk, hogy a mai európai és magyar versenypolitikát a Chicago School, a Harvard School és a Freiburgi Iskola tanításának elemeit egyaránt tartalmazza. Újszerű kutatási irányként, a Rerum Novarum páápai enciklika 120. évfordulója alkalmából megvizsgáltuk, hogy a katolikus egyház társadalmi tanítása hogyan viszonyul a piac versenyhez. Megvizsgáltuk a GVH antitröszt és legfontosabb tisztességtelen kereskedelmi gyakorlati döntéseit is. Végezetül igyekeztünk empirikus módon, közvélemény-kutatás révén is tesztelni, hogy Magyarországon a szabad és tisztességes verseny milyen fogadtatásban részesül. | Our research on the role of competition and competition policy in the EU-member Hungary was based on three pillars. We studied those competition schools of thought which still tend to influence modern competition policy in Hungary and in Europe, especially the Chicago School, the Harvard School and the Freiburg (ordoliberal) School. It was a unprecedented approach in Hungary that we carried out an analysis of the Catholic Church's social teching in relation to free markets and competition on the occasion of the 120th anniversary of the Rerum Novarum. We also prepared studies covering the decisions of the Hungarian competition authority (GVH) in the field of antitrust and deception of consumers. Finally, we construed an in-depth going questionnaire to study empirically how the public perceives the idea of free and fair competition

Circulating miRNA Profiling in Plasma Samples of Ovarian Cancer Patients

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Thoracic aortic strain can affect endograft sizing in young patients

Aortic computed tomography angiography (CTA) examination with electrocardiography gating is becoming the clinical routine image acquisition protocol for diagnosis and intervention planning. To minimize motion artifact, the images are reconstructed in the diastolic phase of the cardiac cycle. The aim of our study was to quantify aortic strain in an elderly nonaneurysmatic patient cohort and to identify the phases of the R-R cycle that correspond to the minimal and maximal aortic diameters. The quantification of aortic strain may enable the improvement of intervention planning and the introduction of more effective dose-saving protocols for CTA scans. Methods: We assessed CTA images of 28 patients (14 men; mean age, 74 years). Aortic calcium score was calculated on native images. Angiography images were reconstructed in equally spaced 10 phases of the R-R cycle. After semiautomatic centerline analysis, we measured the cross-sectional areas in each of the 10 phases at 9 specific segments between the ascending aorta and the common iliac bifurcation representing the attachment sites of thoracic and abdominal stent grafts. Area-derived effective diameter, pulsatility (Amax L Amin), and strain [(Amax L Amin)/Amin] were calculated. Repeated measurements were taken to evaluate inter-reader and intrareader reproducibility (10-10 patients each). Results: A total of 4320 measurements were performed. We found significant difference between diastolic and systolic diameters (DD,Z0 [ 33.2, DS,Z0 [ 34.4; P < .001). Pulsatility values of the vessel diameters were 1.0 to 1.1 mm in the thoracic aorta, 0.7 to 0.9 mm in the abdominal aorta, and 0.5 to 0.6 mm in the common iliac arteries. Negative, moderate correlations were found between aortic strain and age (r [ L0.586; P [ .001), aortic strain and plaque area (r [ L0.429; P [ .026), and age and body mass index (r [ L0.412; P [ .029). We found positive, moderate correlation between age and plaque area (r[0.594; P[.001). The aortic pulsatility curve has a positive extreme at 30% and a negative extreme at 90% of the R-R cycle throughout the aorta. Lin concordance coefficients were 0.987 for inter-reader and 0.994 for intrareader correlations. Conclusions: Aortic strain can be reliably quantified on electrocardiography-gated CTA images. Pulsatility of the aorta can be substantial in the thoracic aortic segments of young patients; therefore, the routine use of systolic images is not recommended. In addition, we demonstrated that images at 30% of the heart cycle correspond to the largest diameter of the aorta

A phase IIa randomized controlled pilot study evaluating the safety and clinical outcomes following the use of rhGDF-5/β-TCP in regenerative periodontal therapy

To present the safety profile, the early healing phase and the clinical outcomes at 24weeks following treatment of human intrabony defects with open flap debridement (OFD) alone or with OFD and rhGDF-5 adsorbed onto a particulate β-tricalcium phosphate (β-TCP) carrier. Twenty chronic periodontitis patients, each with at least one tooth exhibiting a probing depth ≥6mm and an associated intrabony defect ≥4mm entered the study. Ten subjects (one defect/patient) were randomized to receive OFD alone (control) and ten subjects OFD combined with rhGDF-5/β-TCP. Blood samples were collected at screening, and at weeks 2 and 24 to evaluate routine hematology and clinical chemistry, rhGDF-5 plasma levels, and antirhGDF-5 antibody formation. Plaque and gingival indices, bleeding on probing, probing depth, clinical attachment level, and radiographs were recorded pre- and 24weeks postsurgery. Comparable safety profiles were found in the two treatment groups. Neither antirhGDF-5 antibody formation nor relevant rhGDF-5 plasma levels were detected in any patient. At 6months, treatment with OFD + rhGDF-5/β-TCP resulted in higher but statistically not significant PD reduction (3.7 ± 1.2 vs. 3.1 ± 1.8mm; p = 0.26) and CAL gain (3.2 ± 1.7 vs. 1.7 ± 2.2mm; p = 0.14) compared to OFD alone. In the tested concentration, the use of rhGDF-5/β-TCP appeared to be safe and the material possesses a sound biological rationale. Thus, further adequately powered, randomized controlled clinical trials are warranted to confirm the clinical relevance of this new approach in regenerative periodontal therapy. rhGDF-5/β-TCP may represent a promising new techology in regenerative periodontal therap

Circulating epithelial-mesenchymal transition-associated miRNAs are promising biomarkers in ovarian cancer

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Application of heavy mineral analysis for ceramic provenance research by the micromineralogical collection of the Mining and Geological Survey of Hungary – a case study

This study introduces a possible archaeometric application of the micromineralogical collection belonging to the Mining and Geological Survey of Hungary. Micromineralogical (heavy mineral) assemblage of natural clastic sediments (clay, silt, sand) can characterize the plastic ceramic raw materials typical for a delimited region (i.e. a river catchment area or a geological subunit). Heavy mineral investigation is a useful method which can complete conventional ceramic provenance studies applying microscopic petrography and instrumental chemical analyses, especially in cases of very fine-grained pottery or mature, less characteristic ceramic compositions. Using the 10th c. pottery of Edelény-Borsod (NE Hungary) as an example, we present the application of the micromineralogical collection. The study points out the difficulties with the evaluation, i.e. different sample preparation and data collecting strategy for archaeological and geological samples. Finally, the benefits of the results are formulated as conclusions on the ceramic provenance

A CD24 mRNS-expresszió meghatározása kvantitatív valósidejű PCR-módszerrel alacsonyan differenciált szerózus papilláris petefészekrákos szöveti mintákból

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