1,371 research outputs found
Entrance-channel Mass-asymmetry Dependence of Compound-nucleus Formation Time in Light Heavy-ion Reactions
The entrance-channel mass-asymmetry dependence of the compound nucleus
formation time in light heavy-ion reactions has been investigated within the
framework of semiclassical dissipative collision models. the model calculations
have been succesfully applied to the formation of the Ar compound
nucleus as populated via the Be+Si, B+Al,
C+Mg and F+F entrance channels. The shape evolution
of several other light composite systems appears to be consistent with the
so-called "Fusion Inhibition Factor" which has been experimentally observed. As
found previously in more massive systems for the fusion-evaporation process,
the entrance-channel mass-asymmetry degree of freedom appears to determine the
competition between the different mechanisms as well as the time scales
involved.Comment: 12 pages, 3 Figures available upon request, Submitted at Phys. Rev.
Decision-Making Competence and Attempted Suicide
Objective: The propensity of people vulnerable to suicide to make poor life decisions is increasingly well documented. Do they display an extreme degree of decision biases? The present study used a behavioral decision approach to examine the susceptibility of low-lethality and high-lethality suicide attempters to common decision biases, which may ultimately obscure alternative solutions and deterrents to suicide in a crisis. Method: We assessed older and middle-aged individuals who made high-lethality (medically serious; N=31) and low-lethality suicide attempts (N=29). Comparison groups included suicide ideators (N=30), non-suicidal depressed (N=53), and psychiatrically healthy participants (N=28). Attempters, ideators, and non-suicidal depressed participants had unipolar non-psychotic major depression. Decision biases included sunk cost (inability to abort an action for which costs are irrecoverable), framing (responding to superficial features of how a problem is presented), under/overconfidence (appropriateness of confidence in knowledge), and inconsistent risk perception. Data were collected between June of 2010 and February of 2014. Results: Both high- and low-lethality attempters were more susceptible to framing effects, as compared to the other groups included in this study (p< 0.05, ηp2 =.06). In contrast, low-lethality attempters were more susceptible to sunk costs than both the comparison groups and high-lethality attempters (p< 0.01, ηp2 =.09). These group differences remained after accounting for age, global cognitive performance, and impulsive traits. Premorbid IQ partially explained group differences in framing effects. Conclusion: Suicide attempters’ failure to resist framing may reflect their inability to consider a decision from an objective standpoint in a crisis. Low-lethality attempters’ failure to resist sunk cost may reflect their tendency to confuse past and future costs of their behavior, lowering their threshold for acting on suicidal thoughts
Dissipative collisions in O + Al at E=116 MeV
The inclusive energy distributions of fragments (3Z7) emitted in
the reaction O + Al at 116 MeV have been measured in
the angular range = 15 - 115. A non-linear
optimisation procedure using multiple Gaussian distribution functions has been
proposed to extract the fusion-fission and deep inelastic components of the
fragment emission from the experimental data. The angular distributions of the
fragments, thus obtained, from the deep inelastic component are found to fall
off faster than those from the fusion-fission component, indicating shorter
life times of the emitting di-nuclear systems. The life times of the
intermediate di-nuclear configurations have been estimated using a diffractive
Regge-pole model. The life times thus extracted (
Sec.) are found to decrease with the increase in the fragment charge. Optimum
Q-values are also found to increase with increasing charge transfer i.e. with
the decrease in fragment charge.Comment: 9 pages, 4 figures, 1 tabl
8Be cluster emission versus alpha evaporation in 28Si + 12C
The possible occurence of highly deformed configurations in the Ca
di-nuclear system formed in the Si + C reaction is investigated
by analyzing the spectra of emitted light charged particles. Both inclusive and
exclusive measurements of the heavy fragments (A 10) and their
associated light charged particles (protons and particles) have been
made at the IReS Strasbourg {\sc VIVITRON} Tandem facility at bombarding
energies of (Si) = 112 MeV and 180 MeV by using the {\sc
ICARE} charged particle multidetector array. The energy spectra, velocity
distributions, in-plane and out-of-plane angular correlations of light charged
particles are compared to statistical-model calculations using a consistent set
of parameters with spin-dependent level densities. This spin dependence
approach suggests the onset of large nuclear deformation in Ca at high
spin. This conclusion might be connected with the recent observation of
superdeformed bands in the Ca nucleus. The analysis of
particles in coincidence with S fragments suggests a surprisingly strong
Be cluster emission of a binary nature.Comment: 39 pages 15 figure
Search for emission of unstable Be clusters from hot Ca and Ni nuclei
The possible occurence of highly deformed configurations is investigated in
the Ca and Ni di-nuclear systems as formed in the Si +
C and Si + Si reactions, respectively, by using the
properties of emitted light charged particles. Inclusive as well as exclusive
data of the heavy fragments (A 6) and their associated light charged
particles (p, d, t, and -particles) have been collected at the IReS
Strasbourg VIVITRON Tandem facility with two bombarding energies
Si) = 112 and 180 MeV by using the ICARE charged particle
multidetector array, which consists of nearly 40 telescopes. The measured
energy spectra, velocity distributions, in-plane and out-of-plane angular
correlations are analysed by Monte Carlo CASCADE statistical-model calculations
using a consistent set of parameters with spin-dependent level densities.
Although significant deformation effects at high spin are needed, the remaining
disagreement observed in the Si + C reaction for the S
evaporation residue suggests an unexpected large unstable Be cluster
emission of a binary nature.Comment: 13 pages latex, 9 eps figures. Paper presented at the XXXIX
International Winter Meeting on Nuclear Physics, Bormio(Italy) January 22-27,
2001 (to be published at Ricerca Scientifica ed Educazione Permanente
Reaction mechanisms for weakly-bound, stable nuclei and unstable, halo nuclei on medium-mass targets
An experimental overview of reactions induced by the stable, but weakly-bound
nuclei 6Li, 7Li and 9Be, and by the exotic, halo nuclei 6He, 8B, 11Be and 17F
on medium-mass targets, such as 58Ni, 59Co or 64Zn, is presented. Existing data
on elastic scattering, total reaction cross sections, fusion processes, breakup
and transfer channels are discussed in the framework of a CDCC approach taking
into account the breakup degree of freedom.Comment: 7 pages, 6 figures, Invited Talk given by C. Beck to the 10th
International Conference on Nucleus-Nucleus Collisions, August 16-21, 2009
Beijing, China; Paper submitted to the NN2009 Proceedings, Nuclear Physics A
(to be published
Cdx1 and c-Myc Foster the Initiation of Transdifferentiation of the Normal Esophageal Squamous Epithelium toward Barrett's Esophagus
Barrett's esophagus is a premalignant condition whereby the normal stratified squamous esophageal epithelium undergoes a transdifferentiation program resulting in a simple columnar epithelium reminiscent of the small intestine. These changes are typically associated with the stratified squamous epithelium chronically exposed to acid and bile salts as a result of gastroesophageal reflux disease (GERD). Despite this well-defined epidemiologic association between acid reflux and Barrett's esophagus, the genetic changes that induce this transdifferentiation process in esophageal keratinocytes have remained undefined.To begin to identify the genetic changes responsible for transdifferentiaiton in Barrett's esophagus, we performed a microarray analysis of normal esophageal, Barrett's esophagus and small intestinal biopsy specimens to identify candidate signaling pathways and transcription factors that may be involved. Through this screen we identified the Cdx1 homeodomain transcription factor and the c-myc pathway as possible candidates. Cdx1 and c-myc were then tested for their ability to induce transdifferentiation in immortalized human esophageal keratinocytes using organotypic culturing methods. Analyses of these cultures reveal that c-myc and cdx1 cooperate to induce mucin production and changes in keratin expression that are observed in the epithelium of Barrett's esophagus.These data demonstrate the ability of Cdx1 and c-myc to initiate the earliest stages of transdifferentiation of esophageal keratinocytes toward a cell fate characteristic of Barrett's esophagus
Cohort Profile:Health and Wellbeing of People with Intellectual Disability in New South Wales, Australia – A data linkage cohort
Purpose People with intellectual disability (ID) experience high rates of physical and mental health problems, while access to appropriate healthcare is often poor. This cohort was established to develop an epidemiological profile related to the health, health service use, disability services, mortality and corrective services records of people with ID. Participants The cohort contains 92 542 people with ID (40% females) with a median age of 23 years (IQR: 12–43 years) and 2 004 475 people with a neuropsychiatric or developmental disorder diagnosis (50% females) with a median age of 51 years (IQR: 29–73 years) from New South Wales, Australia. The whole sample contains records for 2 097 017 individuals with most data sets spanning financial years 1 July 2001 to 30 June 2016. A wide range of data from linked population data sets are included in the areas of disability, health, corrective services and targeted specialist support services in public schools, Public Guardian and Ombudsman services. Findings to date This study includes one of the largest cohorts of people with ID internationally. Our data have shown that the presence of ID is significantly associated with emergency department presentations and psychiatric readmissions after the first psychiatric admission based on a subcohort of people with a psychiatric admission. Adults with ID experience premature mortality and over-representation of potentially avoidable deaths compared with the general population. Future plans Within the health service system, we will examine different components, that is, inpatient, emergency adult services, children and younger people services and costs associated with healthcare as well as mortality, cause and predictors of death. The neuropsychiatric and developmental disorders comparison cohort allows comparisons of the physical health, mental health and service use profiles of people with ID and those with other neuropsychiatric disorders
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