Bridging the gap between theory and practice in LPV fault detection for flight control actuators

Two different approaches for fault detection,the geometric and the detection filter based methods,are compared in the paper from practical aspects,using the linear parameter-varying (LPV) framework. Presenting two designs allows a comparison of global, system level, and local component level fault detection methods with special emphasis on their relevance to aircraft industry.Practical engineering design decisions are highlighted via applying them to a high-fidelity commercial aircraft problem. The successive steps of the design, including fault modelling, LPV model generation, and LPV FDI filter synthesis, including implementation aspects, are discussed. Results are presented according to the industrial assessment perspectives phrased within the EU ADDSAFE project

Chlamydia pneumoniae in atherosclerotic middle cerebral artery

Background and Purpose—Atherosclerotic middle cerebral arteries are frequent sites of thrombosis, leading to stroke. Previous studies have suggested a role for Chlamydia pneumoniae in the pathogenesis of atherosclerosis. However, the presence of this pathogen in atherosclerotic middle cerebral arteries has heretofore not been documented. In the present study, we analyzed atheromatous plaques from middle cerebral arteries for the presence of C pneumoniae. Methods—Atherosclerotic middle cerebral arteries from 15 cadavers who died of natural causes and corresponding nonatherosclerotic arteries from 4 otherwise healthy trauma victims were examined. Assays for C pneumoniae DNA were carried out by nested polymerase chain reaction (nPCR) specific for the C pneumoniae ompA gene. The presence of the bacterium was assessed by transmission electron microscopy. Results—Five of the 15 atherosclerotic arterial samples and none of the control tissues were positive for C pneumoniae by nPCR. Particles similar in morphology and size to C pneumoniae elementary bodies were detected by transmission electron microscopy in 4 of the 5 nPCR-positive atherosclerotic samples. Conclusions—The demonstration of C pneumoniae in atherosclerotic middle cerebral arteries is consistent with the hypothesis that this bacterium is involved in acute and chronic cerebrovascular diseases