Assessment of biogeochemical processes of Ashtamudi Lake ecosystem in relation to clam fishery

The Ashtamudi Lake ecosystem in Kerala (southwest coast of India) is well known for its clam resources. This estuarine system contributes approximately 80% of the total clam export trade of India besides providing livelihoods for at least 3,000 local people. Among bivalves, clams are an important source of meat for human consumption while its shells are used in the cement industry

Status of India's Exploited Marine Fishery Resources in 2013

The Central Marine Fisheries Research Institute start collected and estimation of marine fish landings for the peninsular coast of India since its inception in 1947, based on a stratified multistage random sampling technique. This which continues to date, and provides knowledge-base for many research, planning and policy initiatives in the marine fisheries sector

Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer

Neuroendocrine carcinomas (NEC) are tumors expressing markers of neuronal differentiation that can arise at different anatomic sites but have strong histological and clinical similarities. Here we report the chromatin landscapes of a range of human NECs and show convergence to the activation of a common epigenetic program. With a particular focus on treatment emergent neuroendocrine prostate cancer (NEPC), we analyze cell lines, patient-derived xenograft (PDX) models and human clinical samples to show the existence of two distinct NEPC subtypes based on the expression of the neuronal transcription factors ASCL1 and NEUROD1. While in cell lines and PDX models these subtypes are mutually exclusive, single-cell analysis of human clinical samples exhibits a more complex tumor structure with subtypes coexisting as separate sub-populations within the same tumor. These tumor sub-populations differ genetically and epigenetically contributing to intra- and inter-tumoral heterogeneity in human metastases. Overall, our results provide a deeper understanding of the shared clinicopathological characteristics shown by NECs. Furthermore, the intratumoral heterogeneity of human NEPCs suggests the requirement of simultaneous targeting of coexisting tumor populations as a therapeutic strategy

Design, Performance, and Calibration of the CMS Hadron-Outer Calorimeter

The CMS hadron calorimeter is a sampling calorimeter with brass absorber and plastic scintillator tiles with wavelength shifting fibres for carrying the light to the readout device. The barrel hadron calorimeter is complemented with an outer calorimeter to ensure high energy shower containment in the calorimeter. Fabrication, testing and calibration of the outer hadron calorimeter are carried out keeping in mind its importance in the energy measurement of jets in view of linearity and resolution. It will provide a net improvement in missing \et measurements at LHC energies. The outer hadron calorimeter will also be used for the muon trigger in coincidence with other muon chambers in CMS

Protocol for efficient plant regeneration and Agrobacterium tumefaciens mediated genetic transformation of pigeonpea

A simple, efficient, reproducible and genotype independent high frequency plant regeneration protocol has been developed from cotyledonary node explants from 12-d-old in vitro raised pigeonpea seedlings cultured on shoot induction medium [Murashige and Skoog (MS) medium + 2.0 mg L-1 benzyladenine]. Shoot-buds originated from the cut ends of the cotyledonary node explants and multiple adventitious shoots developed from 80% of the explants. They elongated rapidly on shoot elongation medium comprising the MS medium supplemented with 0.5 mg L-1 gibberellic acid-A, rooted on MS medium supplemented with 0.5 mg L-1 indole butyric acid (IBA). The survival rate of the in vitro regenerated plantlets was over 70%. The cotyledonary node explants were co-cultivated with Agrobactcrlum tumefaciens strain C-58 harboring the binary plasmid, pCAMBIA1301 [conferring β-glucuronidase (GUS) activity and resistance to hygromycin], cultured on selection medium containing hygromycin to select putatively transformed shoots and rooted. About 24 putative TO transgenic plants have been produced and the stable expression and integration of the transgenes was confirmed by GUS assay, PCR and Southern blot hybridization with a transformation efficiency of over 45%

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Not AvailableThe Ashtamudi Lake ecosystem in Kerala (southwest coast of India) is well known for its clam resources. This estuarine system contributes approximately 80% of the total clam export trade of India besides providing livelihoods for at least 3,000 local people. Among bivalves, clams are an important source of meat for human consumption while its shells are used in the cement industry.Not Availabl