Student interest in intramurals at Boston Public Latin school

Thesis (Ed.M.)--Boston University, 1946. This item was digitized by the Internet Archive

License plate readers: a versatile law enforcement tool with many uses.

Evaluates the usefulness of license plate readers for patrol cars

High resolution root locus plots

A technique is presented for obtaining high resolution root locus plots and Bode diagrams. This is done by translating the origin of coordinates to the area of interest by an appropriate change of variable. The method is applicable to hand calculations or use of a potential analog computer. Examples include the analyses of systems that contain very highly damped, closely spaced pole zero pairs. These are actual design problems encountered in the design of high-speed tracking antenna systems and booster control systems

The Assembly Factor Pet117 Couples Heme a Synthase Activity to Cytochrome Oxidase Assembly

Heme a is an essential metalloporphyrin cofactor of the mitochondrial respiratory enzyme cytochrome c oxidase (CcO). Its synthesis from heme b requires several enzymes, including the evolutionarily conserved heme a synthase (Cox15). Oligomerization of Cox15 appears to be important for the process of heme a biosynthesis and transfer to maturing CcO. However, the details of this process remain elusive, and the roles of any additional CcO assembly factors that may be involved remain unclear. Here we report the systematic analysis of one such uncharacterized assembly factor, Pet117, and demonstrate in Saccharomyces cerevisiae that this evolutionarily conserved protein is necessary for Cox15 oligomerization and function. Pet117 is shown to reside in the mitochondrial matrix, where it is associated with the inner membrane. Pet117 functions at the later maturation stages of the core CcO subunit Cox1 that precede Cox1 hemylation. Pet117 also physically interacts with Cox15 and specifically mediates the stability of Cox15 oligomeric complexes. This Cox15-Pet117 interaction observed by co-immunoprecipitation persists in the absence of heme a synthase activity, is dependent upon Cox1 synthesis and early maturation steps, and is further dependent upon the presence of the matrix-exposed, unstructured linker region of Cox15 needed for Cox15 oligomerization, suggesting that this region mediates the interaction or that the interaction is lost when Cox15 is unable to oligomerize. Based on these findings, it was concluded that Pet117 mediates coupling of heme a synthesis to the CcO assembly process in eukaryotes

Oiling Of The Continental Shelf And Coastal Marshes Over Eight Years After The 2010 Deepwater Horizon Oil Spill

We measured the temporal and spatial trajectory of oiling from the April, 2010, Deepwater Horizon oil spill in water from Louisiana\u27s continental shelf, the estuarine waters of Barataria Bay, and in coastal marsh sediments. The concentrations of 28 target alkanes and 43 target polycyclic aromatic hydrocarbons were determined in water samples collected on 10 offshore cruises, in 19 water samples collected monthly one km offshore at 13 inshore stations in 2010 and 2013, and in 16-60 surficial marsh sediment samples collected on each of 26 trips. The concentration of total aromatics in offshore waters peaked in late summer, 2010, at 100 times above the May, 2010 values, which were already slightly contaminated. There were no differences in surface or bottom water samples. The concentration of total aromatics declined at a rate of 73% y(-1) to 1/1000th of the May 2010 values by summer 2016. The concentrations inside the estuary were proportional to those one km offshore, but were 10-30% lower. The oil concentrations in sediments were initially different at 1 and 10 m distance into the marsh, but became equal after 2 years. Thus, the distinction between oiled and unoiled sites became blurred, if not non-existent then, and oiling had spread over an area wider than was visible initially. The concentrations of oil in sediments were 100-1000 times above the May 2010 values, and dropped to 10 times higher after 8 years, thereafter, demonstrating a long-term contamination by oil or oil residues that will remain for decades. The chemical signature of the oil residues offshore compared to in the marsh reflects the more aerobic offshore conditions and water-soluble tendencies of the dissolved components, whereas the anaerobic marsh sediments will retain the heavier molecular components for a long time, and have a consequential effect on the ecosystems. (C) 2019 The Authors. Published by Elsevier Ltd

The Impact of the 2018 Trade Disruptions on the Iowa Economy

In this analysis, we use historical trade patterns, revenue linkages, and recent futures market price changes to discern the 2018 tariffs’ near-term impacts on the state of Iowa. We use two distinct modeling techniques, and in each technique we make two distinct assumptions. First, we use partial-equilibrium modeling approaches that do not directly consider linkages among the markets and industries across the state of Iowa. In these approaches, two assumptions about price changes are invoked—either the price changes are based upon supply and demand elasticities or the price changes are based upon observations in the futures market. The partial equilibrium techniques look specifically at the corn, soybean, ethanol, and hog markets along with labor and government revenue impacts from changes in these markets. The second technique is a general equilibrium model that examines the trade disruptions across 20 distinct industries in Iowa while taking into account that some industries benefit from tariffs and others do not. In the general equilibrium analysis, we use two scenarios—using price changes estimated from a global model and using observed futures prices—that reflect assumptions about how tariff revenue might return to Iowa. Both modeling techniques and their two sets of assumptions result in four estimates of the trade impacts. The overall impacts across the methodologies are similar. While there is a great deal of uncertainty about the duration of the trade disruptions and the impact these disruptions might have to long-held trade equilibria, the main results of the study are as follows. • Overall losses in Iowa’s Gross State Product are calculated to be $1 to$2 billion (off of a Gross State Product of $190 billion). • Overall losses to Iowa’s Soybean industry of$159 to $891 million, with an average revenue loss across all models of$545 million (Iowa soybeans are a $5.2 billion industry). • Overall losses to Iowa’s Corn industry of$90 to $579 million, with an average revenue loss across all models of$333 million (Iowa corn is an $8.5 billion industry). • Overall losses to Iowa’s Pork/Hog industry of$558 to $955 million, with an average revenue loss across all models of$776 million (the Iowa pork/hog industry is a $7.1 billion industry). • A 2$105 million in lost revenues to Iowa ethanol producers. • Revenue losses in these industries translate into additional lost labor income across the state. Labor income declines from the impacts to the corn, soybean, and hog industries range from $366 to$484 million without federal offsets and $245 to$364 million with federal offsets. • Iowa tax revenue losses (personal income and sales taxes) range from $111 to$146 million. Federal offsets would reduce tax losses to $75 to$110 million

TIMED Imaging Photometer Experiment (TIPE)

This document contains a summary of the TIMED Imaging Photometer Experiment (TIPE) instrument study at the time of the termination of project due to TIPE being de-selected from the Thermosphere, Ionosphere and Mesosphere Energetics and Dynamics (TIMED) mission

Longitudinal Screening Detects Cognitive Stability and Behavioral Deterioration in ALS Patients

Objective. To evaluate longitudinal cognitive/behavioral change over 12 months in participants enrolled in the ALS Multicenter Cohort Study of Oxidative Stress (ALS COSMOS). Methods. We analyzed data from 294 ALS participants, 134 of whom were studied serially. Change over time was evaluated controlling for age, sex, symptom duration, education, race, and ethnicity. Using multiple regression, we evaluated associations among decline in ALS Functional Rating Scale-Revised (ALSFRS-R) scores, forced vital capacity (FVC), and cognitive/behavioral changes. Change in cognitive/behavioral subgroups was assessed using one-way analyses of covariance. Results. Participants with follow-up data had fewer baseline behavior problems compared to patients without follow-up data. We found significant worsening of behavior (ALS Cognitive Behavioral Screen (ALS CBS) behavioral scale, p \u3c 0.001; Frontal Behavioral Inventory-ALS (FBI-ALS) disinhibition subscale, p = 0.044). Item analysis suggested change in frustration tolerance, insight, mental rigidity, and interests (p \u3c 0.05). Changes in ALSFRS-R correlated with the ALS CBS. Worsening disinhibition (FBI-ALS) did not correlate with ALSFRS-R, FVC, or disease duration. Conclusion. We did not detect cognitive change. Behavioral change was detected, and increased disinhibition was found among patients with abnormal baseline behavioral scores. Disinhibition changes did not correlate with disease duration or progression. Baseline behavioral problems were associated with advanced, rapidly progressive disease and study attrition