Archon Genomics X PRIZE Validation Protocol

This document is a collective assembly of techniques designed to test the quality and accuracy of 100 whole human genome sequences resulting from the $10 Million Archon Genomics X PRIZE (AGXP) competition. The purpose of this article is to enlist constructive criticism from the genomic and genetic community on the outlined approaches. The intent for the final version of this Validation Protocol is to become a useful standard by which to gauge the capabilities of whole genome sequencing technologies that emerge even after 2012

A Survey and Evaluation of Creative Writing through the Media of Individualized Movies in the Seventh Grade

It was the purpose of this study to determine if creative writing could be improved through the motivation of individualized movies as compared to the standard creative writing assignment

Bathymetry of the Chesapeake Bay

Coordinates: W 77⁰30ʹ--W 75⁰30ʹ/N 39⁰30ʹ--N 37⁰. Bathymetry based on depths from National Ocean Survey sounding sheets, contoured to mean low water datum. Scale 1:224,700 at 37⁰ latitude. Original chart size 141x80cm. | 55.5x31.5inches Bathymetric Chart Series No. 2

Blood Sugar Changes in the Rat Produced by Salt of Beryllium, Magnesium, and Zinc with Some Observations on Hemoglobin and Red Blood Corpuscles

This report is the direct result of research in this laboratory upon the physiological role of several metallic salts. The influence of magnesium salts upon the blood sugar content of rabbits was studied by Underhill (1) who found that hyperglycemia subsequent to magnesium injection was most evident during the period of anesthesia. Meltzer and Auer (2) had shown that an animal anesthetized by an injection of magnesium sulfate could be quickly restored to normal by an intravenous injection of calcium chloride. Underhill (1) showed that the hyperglycemia produced in rabbits anesthetized with magnesium salt was reduced to normal in two or three hours time by calcium chloride. Salant and Wise (3) observed the production of glycosuria in rabbits by zinc salts. They gave results which show that an intravenous injection of zinc malate caused hyperglycemia and glycosuria. These workers report that intravenous injection of calcium chloride did not cause a decrease in the glycosuria resulting from the zinc malate injection. They did not report the effect of calcium chloride upon the blood sugar

Historical shoreline changes and wave refraction analysis, Smith Island, Chesapeake Bay : final report

The objective of this study was to develop wave and sediment transport estimates (based on wave refraction analysis and historical shoreline change analysis) for the western shoreline of the Chesapeake Bay Smith Island area

Public Health Policy: Internet Access to Advance Health Equity

Internet access could be the 21st century’s great equalizer, interrupting access barriers that negatively impact health. Mississippi reigns as the poorest state in the nation (CB, 2020), with some of the country’s worst health outcomes (UHF, 2022), particularly among rural populations. The Community Engagement Center (CEC), one of three Jackson Heart Study (JHS) centers, leverages community partnerships and connections to improve public health. In these times of public health crises, connections are relevant - that is, internet connections. Internet, or broadband, access is the far upstream approach needed to improve the social determinants that negatively impact Mississippians’ health. The National Academy of Medicine says it best, “Everyone in this country deserves the opportunity to be healthy and reach their full potential no matter who they are or where they live” (NAM, 2021, para 1). Simply living in the beautiful state of Mississippi should not be an automatic predictor of excess morbidity and early mortality. Mississippi public health advocates must promote increased internet access, to break down long-standing barriers and maximize the health and well-being of all Mississippians

Detailed Bathymetry of Selected Areas of the Inner continental Shelf of the Virginian Sea: Southeastern Virginia, Virginia Beach, and Wachapreague, Virginia

The increased need for information involving the physical processes affecting the inner continental shelf has led to these detailed compilations of the nearshore bathymetric data of the Virginian coastline. For example, the growth of population has increased the usage of our beaches for recreation. Contrived short-term and the apparent long-term shortages of fuel, so recently impressed upon the public, have initiated an intensive study of the adjacent continental shelf area for possible future sites of offshore drilling rigs, power plants and port facilities. Among the basic oceanographic information required in all such studies is detailed depth information. To help meet these needs we have prepared these detailed bathymetric maps containing significantly more information than has previously been compiled and made available from this region of the Atlantic shelf

Isometric exercise-induced hemodynamic load strongly predicts left ventricular mass in hypertension

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Growth, Reproduction, and Blood Changes Produced in Rats by Means of Zinc Carbonate

The literature bearing on the toxicity of zinc to the animal body is very confused. D\u27Amore, Falcone, and Marmaldi (1) fed zinc oxide to dogs; they called attention to the loss of appetite and the weak condition of their animals with the further observation that the blood color and the number of red cells were greatly diminished. During the last days of the poisoning, the white cells markedly increased. Urine of the dogs was diminished in volume and contained casts and albumin. Lehmann (2) fed zinc carbonate to dogs for eleven months with no evidence of poisoning. Batchelor, Fehnel, Thompson, and Drinker (3) observed no anemia from administration of zinc. More recent studies have been made by Heller and Burke (4) and Myers, Beard and Broda (5). The latter investigators (5) fed adult rats zinc chloride to the extent of one per cent of zinc and observed that, while the body weight remained constant, the hemoglobin was reduced from 14.3 to 11.1 grams per cent; but the red cells did not change in number. Myers and Beard (6) also found, when zinc chloride was used to supplement iron chloride in blood regeneration, that more than one-tenth of a milligram of zinc daily prolonged the time necessary for the blood to be restored to normal. Keil and Nelson (7) fed two-tenths of a milligram of zinc as zinc chloride daily to rats, without any effect upon the rate of development of anemia