The Behavioural Consequences of the Implicit and Explicit Dehumanization of Refugees

The present research investigated the behavioural consequences in a social interaction of implicit and explicit refugee dehumanization. To this end, this research employed an experimental design in which 93 undergraduate students interacted with a confederate whom they either believed to be a refugee or a Canadian student. The interaction was videotaped and coded for participants’ positivity of nonverbal and verbal behaviours. The results showed that increased implicit refugee dehumanization predicted less positive nonverbal behavior, and that increased explicit refugee dehumanization tended to predict less positive interaction quality based on participants’ verbal behaviour. Based on these results, the present research also investigated the following two subsidiary research questions utilizing data from the same study. First, does implicit refugee dehumanization predict specific nonverbal behaviours that are indicative of anxiety or general uneasiness and specific nonverbal behaviours that are indicative of happiness or comfort? Second, do implicit and explicit refugee dehumanization predict changes in the positivity of participants’ nonverbal and verbal behavior, as well as their specific nonverbal behaviours (e.g., self-touch, facial rigidity), from the beginning to the end of the interaction with a refugee? The results showed that implicit refugee dehumanization and the type of interaction partner (refugee versus Canadian) influenced the extent to which participants had rigid faces, smiled or touched themselves throughout the interaction. In terms of change over time, the results showed that participants’ tendency to implicitly dehumanize refugees determined their nonverbal behaviour at the beginning of the interaction. For example, at the beginning of the interaction, participants who implicitly dehumanized refugees displayed less positive nonverbal behaviours, had more rigid faces and smiled less when interacting with a refugee compared to a Canadian. As the action unfolded, however, participants’ nonverbal behaviours ecame more positive regardless of their implicit refugee dehumanization scores and experimental condition. Participants’ verbal behaviour as well as participants’ specific nonverbal behaviours did not change over time, on average. The present research is the first demonstration that implicit and explicit refugee dehumanization have behavioural consequences in a social interaction

Intranasal Delivery of MVA Vector Vaccine Induces Effective Pulmonary Immunity Against SARS-CoV-2 in Rodents

Antigen-specific tissue-resident memory T cells (Trms) and neutralizing IgA antibodies provide the most effective protection of the lungs from viral infections. To induce those essential components of lung immunity against SARS-CoV-2, we tested various immunization protocols involving intranasal delivery of a novel Modified Vaccinia virus Ankara (MVA)-SARS-2-spike vaccine candidate. We show that a single intranasal MVA-SARS-CoV-2-S application in mice strongly induced pulmonary spike-specific CD8+ T cells, albeit restricted production of neutralizing antibodies. In prime-boost protocols, intranasal booster vaccine delivery proved to be crucial for a massive expansion of systemic and lung tissue-resident spike-specific CD8+ T cells and the development of Th1 - but not Th2 - CD4+ T cells. Likewise, very high titers of IgG and IgA anti-spike antibodies were present in serum and broncho-alveolar lavages that possessed high virus neutralization capacities to all current SARS-CoV-2 variants of concern. Importantly, the MVA-SARS-2-spike vaccine applied in intramuscular priming and intranasal boosting treatment regimen completely protected hamsters from developing SARS-CoV-2 lung infection and pathology. Together, these results identify intramuscular priming followed by respiratory tract boosting with MVA-SARS-2-S as a promising approach for the induction of local, respiratory as well as systemic immune responses suited to protect from SARS-CoV-2 infections

The portrayal of refugees in Canadian newspapers: The impact of the arrival of Tamil refugees by sea in 2010

News media make an essential contribution to the way in which the public processes and understands controversial issues such as the arrival of refugees in western countries. Indeed, they can have an important role in shaping the public’s responses to these issues by framing arguments to encourage a particular interpretation of an issue. The current research investigates how refugees were portrayed before and after the controversial arrival of a ship carrying Tamil refugees to Canada in August 2010. The study was based on the content analysis of 102 articles published in six Canadian newspapers six months before and six months after the event. The newspapers were selected based on their large circulation and diverse political slants. The analyses revealed substantial variation in the extent to which the newspapers reported on the issue of refugee arrivals, as well as in their portrayals of refugees. Liberal newspapers were more likely than conservative newspapers to include reports on issues surrounding refugees and were more likely to portray refugees as victims. Also, the analyses demonstrated the impact of the arrival of the Tamil refugee ship on the portrayal of refugees. Whereas before the event refugees were portrayed more in terms of false claims for refugee status, after the event refugees were portrayed more in terms of being either criminals and terrorists or victims. These results have important implications for how refugees are perceived and treated in society, including what kind of policies are implemented to handle refugee claims and what type of assistance is provided to refugees

Decay of Sabin inactivated poliovirus vaccine (IPV)-boosted poliovirus antibodies

Introduction: We conducted a follow-on study to a phase I randomized, controlled trial conducted in Cuba, 2012, to assess the persistence of poliovirus antibodies at 21–22 months following booster dose of Sabin-IPV compared to Salk-IPV in adults who had received multiple doses of oral poliovirus vaccine (OPV) during childhood. Methods: In 2012, 60 healthy adult males aged 19–23 were randomized to receive one booster dose, of either Sabin-inactivated poliovirus vaccine (Sabin-IPV), adjuvanted Sabin-IPV (aSabin-IPV), or conventional Salk-IPV. In the original study, blood was collected at days 0 (before) and 28 (after vaccination), respectively. In this study, an additional blood sample was collected 21–22 months after vaccination, and tested for neutralizing antibodies to Sabin poliovirus types 1, 2 and 3. Results: We collected sera from 59/60 (98.3%) subjects; 59/59 (100%) remained seropositive to all poliovirus types, 21–22 months after vaccination. The decay curves were very similar among the study groups. Between day 28 and 21–22 months, there was a reduction of ⩾87.4% in median antibody levels for all poliovirus types in all study groups, with no significant differences between the study groups. Conclusion: The decay of poliovirus antibodies over a 21–22-month period was similar regardless of the type of booster vaccine used, suggesting the scientific data of Salk IPV long-term persistence and decay may be broadly applicable to Sabin IPV

Dynamic corrosion testing of metals in solar salt for concentrated solar power

ABSTRACT: Potassium nitrate and sodium nitrate in mixing proportion of KNO3-NaNO3 40-60 wt% (also called solar salt) has been successfully used for over a decade as heat storage medium for concentrated solar power parabolic-trough collector plants at temperatures up to 400 degrees C. At temperatures of 560 degrees C, reached in state-of-the-art solar tower systems, corrosion of metallic components in contact with solar salt can become an issue and has caused leaks and plant shut-downs in recently built tower projects. While the corrosion rates of several materials have been determined for different temperatures in static molten salt immersion experiments, there is a lack of corrosion data for dynamic in-service conditions. In this work, a dynamic corrosion test has been conducted on 19 different material types including protective coatings, mimicking flow-rate, temperature gradient and draining of inservice operation of a receiver in a concentrated solar power tower. The measured corrosion rates are presented and compared to static corrosion tests reported in literature.info:eu-repo/semantics/publishedVersio

Single MVA-SARS-2-ST/N Vaccination Rapidly Protects K18-hACE2 Mice against a Lethal SARS-CoV-2 Challenge Infection

The sudden emergence of SARS-CoV-2 demonstrates the need for new vaccines that rapidly protect in the case of an emergency. In this study, we developed a recombinant MVA vaccine co-expressing SARS-CoV-2 prefusion-stabilized spike protein (ST) and SARS-CoV-2 nucleoprotein (N, MVA-SARS-2-ST/N) as an approach to further improve vaccine-induced immunogenicity and efficacy. Single MVA-SARS-2-ST/N vaccination in K18-hACE2 mice induced robust protection against lethal respiratory SARS-CoV-2 challenge infection 28 days later. The protective outcome of MVA-SARS-2-ST/N vaccination correlated with the activation of SARS-CoV-2-neutralizing antibodies (nABs) and substantial amounts of SARS-CoV-2-specific T cells especially in the lung of MVA-SARS-2-ST/N-vaccinated mice. Emergency vaccination with MVA-SARS-2-ST/N just 2 days before lethal SARS-CoV-2 challenge infection resulted in a delayed onset of clinical disease outcome in these mice and increased titers of nAB or SARS-CoV-2-specific T cells in the spleen and lung. These data highlight the potential of a multivalent COVID-19 vaccine co-expressing S- and N-protein, which further contributes to the development of rapidly protective vaccination strategies against emerging pathogens

Mediated discourse at the European Parliament: Empirical investigations

The purpose of this book is to showcase a diverse set of directions in empirical research on mediated discourse, reflecting on the state-of-the-art and the increasing intersection between Corpus-based Interpreting Studies (CBIS) and Corpus-based Translation Studies (CBTS). Undeniably, data from the European Parliament (EP) offer a great opportunity for such research. Not only does the institution provide a sizeable sample of oral debates held at the EP together with their simultaneous interpretations into all languages of the European Union. It also makes available written verbatim reports of the original speeches, which used to be translated. From a methodological perspective, EP materials thus guarantee a great degree of homogeneity, which is particularly valuable in corpus studies, where data comparability is frequently a challenge. In this volume, progress is visible in both CBIS and CBTS. In interpreting, it manifests itself notably in the availability of comprehensive transcription, annotation and alignment systems. In translation, datasets are becoming substantially richer in metadata, which allow for increasingly refined multi-factorial analysis. At the crossroads between the two fields, intermodal investigations bring to the fore what these mediation modes have in common and how they differ. The volume is thus aimed in particular at Interpreting and Translation scholars looking for new descriptive insights and methodological approaches in the investigation of mediated discourse, but it may be also of interest for (corpus) linguists analysing parliamentary discourse in general.