Synthesis of fluorescent carboxylic acid ligands for construction of monolayers on nanostructures

Abstract Two new long-chain carboxylic acids (1, 2) bearing strong fluorescent group pyrene as ligands for Self-Assembled Monolayers (SAMs) have been synthesized. The multistep targeted synthesis is accomplished by use of Pyren-1-yl methylamine hydrochloride and employing simplified synthetic protocols. Compound 2 contains a chiral center purposely introduced along the atom chain in order to make it suitable for chiro-optical studies of the resulting SAMs

Synthesis of fluorescent long-chain thiols/disulfides as building-blocks for self-assembled monolayers preparation

Abstract New symmetrical disulfides together with the corresponding thiols bearing fluorescent end-groups have been synthesized as building-blocks for self-assembled monolayers (SAMs). The synthesis has been accomplished starting from aromatic nitrogen heterocycles in three steps. The conversion of the tosylated intermediate into the final disulfide is accomplished by use of sodium hydrogen sulfide (NaSH). Both products (thiols and disulfides) were isolated and characterized

Anti termite activity of Jatropha curcas Linn. biochemicals

Jatropha curcas oil and its toxic fraction were evaluated at different dilutions i.e., 1%,5%,10%,20% against Microcerotermes beesoni, the test termite. The maximum wood protection against termites of both the treatments were obtained at their highest concentration i.e. 20%. The weight loss ranged from 18.77% to 48.80% at concentrations of 20% to 1% of Jatropha curcas oil formulation. The protection afforded by toxic fraction was enhanced, with the % weight loss ranging from 10.48 to 35.19. However, all the treatments proved to be effective over the control (50.84%

Advertising Effectiveness In Events

Confronted with decreasing effectiveness of the classic marketing communications, events have become an increasingly popular alternative for marketers. Events constitute one of the most exciting and fastest growing forms of leisure and business. With time, the decreasing effectiveness of classical marketing communications boosted the use of events for marketing and making brand awareness. Event marketing is seen as the unique opportunity to integrate the firm’s communication activities like public relations, advertising, and direct marketing, in a sense which enables consumers to interact with brands. The basic objective of any industry is to deliver the product in market with making profits and merchandising. This can be done with the help increase in sales at remunerative prices. Advertising is the major player for reach of products and services to the consumers and a varied method of publicity. American Marketing Association (2006) defines advertising as “any paid form of non personal presentation and promotion of ideas, goods and/or services by identified sponsor” (Kotler and Keller, 2009). This particular researcher paper focuses on the advertising effectiveness in (sports) events, London Olympic Games 2012. The focus of particular research is to gather knowledge from attendee’s about the sponsors advertisements and products. Research work entails on understanding the effectiveness of advertisements by sponsors for promoting and maintaining brand image in public. Study conducts 40 semi-structured interviews to understand the aspects of advertising effectiveness, and also explore the emotional and cognitive effects that advertisements generate. Henceforth, the research is conducted on London Olympics a mega sports event to understand the advertising effectiveness. Event marketing (advertisements) thus links a company’s brand to an activity for the purpose for creating experiences for attendees and promoting brand or product/service. The focus relies on what advertising effect the consumers have and how information is conveyed to consumers

DEVELOPMENT OF THERMOSENSITIVE GEL OF FLUCONAZOLE FOR VAGINAL CANDIDIASIS

Objective: The aim of the present study was to develop in-situ gelling formulations of Fluconazole (FCZ) using thermosensitive polymer for treatment of vaginal Candidiasis.Methods: In-situ gelling formulations of FCZ (1 % w/w) were prepared with different concentrations of Poloxamer 407 (P 407, 15-20% w/w) using the cold dispersion method. Similarly,  formulations were also prepared by adding mucoadhesive polymers like hydroxyethyl cellulose, Polycarbophil, Carbopol 974 and Hydroxypropyl methylcellulose E 50 LV (0.4 % w/w) to the P 407 formulations. These formulations were evaluated for appearance, clarity, pH, gelling ability, gelling time, gelling temperature, viscosity (in sol and gel forms), spreading time, ex-vivo mucoadhesion, in-vitro dissolution, morphological characteristics by SEM and in-vitro antifungal efficacy against Candida albicance. In-vivo vaginal irritation of developed formulation was assessed in New Zealand female rabbits. Results: In-situ gelling formulation of FCZ, prepared using 18 % w/w P407 and 0.4 % hydroxyethyl cellulose, was optimized since this formulation was found to be clear, transparent, forming a quick and stable gel with shear thinning behaviour and excellent mucoadhesion. The developed formulation released 74.21% of FCZ after 8 h of dissolution in 5.2 pH citrate buffer. In-vitro antifungal activity against Candida albicance showed the stronger antifungal activity of formulation as compared to a marketed formulation. In-vivo vaginal irritation study in rabbits demonstrated no significant irritation after 10 d of exposure to the formulation. Conclusion: The study demonstrated that in-situ gelling formulation of FCZ prepared using thermosensitive polymer had improved activity against Candida albicance and would be efficacious for the treatment of vaginal Candidiasis

Advertising Effectiveness In Events

Confronted with decreasing effectiveness of the classic marketing communications, events have become an increasingly popular alternative for marketers. Events constitute one of the most exciting and fastest growing forms of leisure and business. With time, the decreasing effectiveness of classical marketing communications boosted the use of events for marketing and making brand awareness. Event marketing is seen as the unique opportunity to integrate the firm’s communication activities like public relations, advertising, and direct marketing, in a sense which enables consumers to interact with brands. The basic objective of any industry is to deliver the product in market with making profits and merchandising. This can be done with the help increase in sales at remunerative prices. Advertising is the major player for reach of products and services to the consumers and a varied method of publicity. American Marketing Association (2006) defines advertising as “any paid form of non personal presentation and promotion of ideas, goods and/or services by identified sponsor” (Kotler and Keller, 2009). This particular researcher paper focuses on the advertising effectiveness in (sports) events, London Olympic Games 2012. The focus of particular research is to gather knowledge from attendee’s about the sponsors advertisements and products. Research work entails on understanding the effectiveness of advertisements by sponsors for promoting and maintaining brand image in public. Study conducts 40 semi-structured interviews to understand the aspects of advertising effectiveness, and also explore the emotional and cognitive effects that advertisements generate. Henceforth, the research is conducted on London Olympics a mega sports event to understand the advertising effectiveness. Event marketing (advertisements) thus links a company’s brand to an activity for the purpose for creating experiences for attendees and promoting brand or product/service. The focus relies on what advertising effect the consumers have and how information is conveyed to consumers

Erratum to: "Synthesis of fluorescent carboxylic acid ligands for construction of monolayers on nanostructures"

© Versita Sp. z o.o. Received 25 July 2012; Accepted 30 July 2012 The original version of the article was published in Cent. Eur. J. Chem. 10(5) (2012) pp. 1640-1646. Unfortunately, the original version of this article contains a mistake in the affiliation section. Dr Sushilkumar A. Jadhav's first affiliation is Department of Material Science and Chemical Engineering, Politecnico di Torino, 10129 Torino, Italy Cent. Eur. J. Chem. • 10(6) • 2012 • 1980 DOI: 10.2478/s11532-012-0112-