Synthesis of Bifunctional Poly(Vinyl Phosphonic Acid-co-glycidyl Metacrylate-co-divinyl Benzene) Cation-Exchange Resin and Its Indium Adsorption Properties from Indium Tin Oxide Solution

ABSTRACT Poly(vinyl phosphonic acid-co-glycidyl methacrylate-co-divinyl benzene) (PVGD) and PVGD containing an iminodiacetic acid group (IPVGD), which has indium ion selectivity, were synthesized by suspension polymerization, and their indium adsorption properties were investigated. The synthesized PVGD and IPVGD resins were characterized using Fourier transform infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS) and mercury porosimetry. The cation-exchange capacity, the water uptake and the indium adsorption properties were investigated. The cation-exchange capacities of PVGD and IPVGD were 1.2 -4.5 meq/g and 2.5 -6.4 meq/g, respectively. The water uptakes were decreased with increasing contents of divinyl benzene (DVB). The water uptake values were 25% -40% and 20% -35%, respectively. The optimum adsorption of indium from a pure indium solution and an artificial indium tin oxide (ITO) solution by the PVGD and IPVGD ion-exchange resins were 2.3 and 3.5 meq/g, respectively. The indium adsorption capacities of IPVGD were higher than those of PVGD. The indium ion adsorption selectivity in the artificial ITO solution by PVGD and IPVGD was excellent, and other ions were adsorbed only slightly

Separated Fetus-in-fetu In Retroperitoneum

Fetus-in-fetu is an extremely rare enigmatic condition, every case of which should be carefully examined, particularly for the distinction between it and a mature teratoma and the determination of its embryopathogenesis. This report deals with a case of fetus-in-fetu that was found in two parts. The host(autosite) was a 14month- old boy who first presented with a back mass. A large round mass, 7 X 6 X 6cm, was removed from the left upper retroperitoneum. The mass was cystic containing 200ml of yellow serous fluid and consisted of two separate masses. One part resembled a stunted dysmorphic fetus, while the other was an amorphous lump, which disclosed a sacrococcygeal bone with five vertebrae. Histologically, both masses showed largely regressed digestive, respiratory, and musculoskeletal tissue. However, the parenchymal organs were missing. Definite vertebral bones, intervertebral discs, and spinal cord remnant were found

Clinical Outcomes of Single-level Posterior Percutaneous Endoscopic Cervical Foraminotomy for Patients with Less Cervical Lordosis

Objective Posterior percutaneous endoscopic cervical foraminotomy (P-PECF) is a minimally invasive surgical technique for treatment of cervical radiculopathies. Application of P-PECF to patients with preexisting loss of cervical curvature (<10°) is still controversial because violation to facet joint may lead to kyphotic change. Clinical outcomes of P-PECF was analyzed and compared according to preoperative cervical curvature. Methods In this retrospective nested case-control study, 71 patients who underwent P-PECF due to foraminal soft disc herniation or bony stenosis were reviewed. P-PECF was performed by a single senior surgeon, and surgical methods were as previously described. Visual analogue pain scale on arm (Arm-VAS) was assessed preoperatively and postoperatively (1, 3, 6, 12 month and yearly thereafter). All patients were clinically followed for 24.5±20.0 months. The minimal clinically important difference of the Arm-VAS was set at 2.5. Patients with preoperative cervical curvature ≥10° were included in group I (n=32) and cervical curvature <10° or kyphosis were included in the group II (n=39). Results At the last follow up, 68/71 (96%) patients showed significant reduction of arm pain (Pre-operation, 7.4±2.0; post-operation, 1.5±2.0) after 1.74±0.29 months (95% CI; 1.18-2.31). The preoperative cervical curvature did not influence the outcome (p=0.4, T-test) and time to reach the clinical endpoint (p=0.34, Cox-logistic regression analysis). Conclusion P-PECF effectively reduced radicular pain due to foraminal soft disc herniation or stenosis. Preexisting loss of lordosis is not a risk factor for outcomes of P-PECF

The Response of CMS Combined Calorimeters to Single Hadrons, Electrons and Muons

We report on the response of the combined CMS electromagnetic (EB) and hadronic barrel (HB) calorimeters to hadrons, electrons and muons in a wide momentum range from 1 to 350 GeV/c. To our knowledge, this is the widest range of momenta in which any calorimeter system is studied. These tests, carried out at the H2 beam-line at CERN, provide a wealth of information, especially at low energies. We analyze in detail the differences in total calorimeter response to charged pions, kaons, protons and antiprotons and discuss the underlying phenomena. These data will play a crucial role in the thorough understanding of jets in CMS

Tandem High-Dose Chemotherapy and Autologous Stem Cell Transplantation in Young Children with Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System

The feasibility and effectiveness of tandem high-dose chemotherapy and autologous stem cell transplantation (HDCT/autoSCT) were evaluated in children younger than 3 yr of age with atypical teratoid/rhabdoid tumors (ATRT). Tandem HDCT/autoSCT was administered following six cycles of induction chemotherapy. Radiotherapy (RT) was administered if the tumor relapsed or progressed, otherwise, it was administered after 3 yr of age. Tumors relapsed or progressed during induction chemotherapy in 5 of 9 patients enrolled; 3 of these 5 received tandem HDCT/autoSCT as a salvage treatment. One patient died from sepsis during induction chemotherapy. The remaining 3 patients proceeded to tandem HDCT/autoSCT; however, 2 of these patients showed tumor relapse/progression after tandem HDCT/autoSCT. All 7 relapses/progressions occurred at primary sites even in patients with leptomeningeal seeding. Toxicities during tandem HDCT/autoSCT were manageable. A total of 5 patients were alive with a median follow-up of 20 (range 16-70) months from diagnosis. Four of 5 patients who received RT after relapse/progression are alive. The probability of overall survival at 3 yr from diagnosis was 53.3% ± 17.3%. Our tandem HDCT/autoSCT is feasible; however, early administration of RT prior to tandem HDCT/autoSCT should be considered to improve the outcome after tandem HDCT/autoSCT

Purification and characterization of angiotensin-1 converting enzyme (ACE)-inhibitory peptide from the jellyfish, Nemopilema nomurai

The Nemopilema nomurai hydrolysate was produced by the reaction of papain, and an angiotensin-Ι converting enzyme (ACE)-inhibitory peptide was purified by using the molecular cut-offs membrane filter, the gel filtration chromatography with Sephadex LH-20 and the reverse phase chromatographic method using C18 and C12 columns. Purification yield of the active peptide was estimated to be 0.2 ± 0.1%, starting from the lyophilized jellyfish. The infrared (IR), proton nuclear magnetic resonance spectroscopy (1H NMR), carbon nuclear magnetic resonance (13C NMR) and mass spectrometry (MS) spectrometer analyses elucidated that the structure of the purified peptide is tyrosine-isoleucine (Tyr-Ile). The inhibitory concentration at 50% (IC50) and Ki values were calculated to be 2.0 ± 0.3 μg/ml and 3.3 ± 0.3 μM, respectively, which acts as a competitive inhibitor to ACE.Keywords: Angiotensin-Ι converting enzyme, Jellyfish, Nemopilema nomurai, Papain hydrolysate, Tyrosine-IsoleucineAfrican Journal of Biotechnology Vol. 12(15), pp. 1888-189

Pathological Classification of the Intramedullary Spinal Cord Tumors According to 2021 World Health Organization Classification of Central Nervous System Tumors, a Single-Institute Experience

According to the new 2021 World Health Organization (WHO) classification of tumors of the central nervous system (CNS) the classification of the primary intramedullary spinal cord tumors (IM-SCT) follows that of CNS tumors. However, since the genetics and methylation profile of ependymal tumors depend on the location of the tumor, the ‘spinal (SP)’ should be added for the ependymoma (EPN) and subependymoma (SubEPN). For an evidence-based review, the authors reviewed SCTs in the archives of the Seoul National University Hospital over the past decade. The frequent pathologies of primary IM-SCT were SP-EPN (45.1%), hemangioblastoma (20.0%), astrocytic tumors (17.4%, including pilocytic astrocytoma [4.6%] and diffuse midline glioma, H3 K27-altered [4.0%]), myxopapillary EPN (11.0%), and SP-subEPN (3.0%) in decreasing order. IDH-mutant astrocytomas, oligodendrogliomas, glioneuronal tumors, embryonal tumors, and germ cell tumors can occur but are extremely rare in the spinal cord. Genetic studies should support for the primary IM-SCT classification. In the 2021 WHO classifications, extramedullary SCT did not change significantly but contained several new genetically defined types of mesenchymal tumors. This article focused on primary IM-SCT for tumor frequency, age, sex difference, pathological features, and genetic abnormalities, based on a single-institute experience