Organic farming without fossil fuels - life cycle assessment of two Swedish cases

Organic agriculture is dependent on fossil fuels, just like conventional agriculture, but this can be reduced by the use of on-farm biomass resources. The energy efficiency and environmental impacts of different alternatives can be assessed by life cycle assessment (LCA), which we have done in this project. Swedish organic milk production can become self-sufficient in energy by using renewable sources available on the farm, with biogas from manure as the main energy source. Thereby greenhouse gas (GHG) emissions from the production system can be reduced, both by substituting fossil fuels and by reducing methane emissions from manure. The arable organic farm studied in the project could be self-sufficient in energy by using the residues available in the crop rotation. Because of soil carbon losses, the greenhouse gas emission savings were lower with the use of straw ethanol, heat and power (9%) than by using ley for biogas production (35%). In this research project, the system boundaries were set at energy self-sufficiency at farm or farm-cluster level. Heat and fuel were supplied as needed, and electricity production was equal to use on an annual basis. In practice, however, better resource efficiency can be achieved by making full use of available energy infrastructure, and basing production on resource availability and economic constraints, rather than a narrow self-sufficiency approach

A Morettian literary atlas of Naguib Mahfouz\u27s Cairo in three early realist novels: Cairo modern, Khan al-Khalili, and Midaq alley

This thesis includes a variey of “literary map experiements” on a dataset of mappable, non-generic, places found in three early realist “Cairo novels” by Naguib Mahfouz: Cairo Modern (1945), Khan al-Khalili (1946) and Midaq Alley (1947) and analyses of the mapped results. Experiments in the “atlas” are conducted on each novel separately and – in a more ‘distant” reading – on combinations of the three novels. The methodology is one originated by Stanford literary historian Franco Moretti in his Atlas of the European Novel 1800-1900 and Graphs, Maps, Trees: Abstract Models for a Lierary History. To the researcher’s knowledge, this is the first time Moretti’s map methodology has been applied to Arab realist literature. The final discussion section compares places in the author’s own life up to 1947 with those included in the three novels. The original dataset, included in the appendices as a series of spreadsheets, is based on AUC Press’s English translations of the three novels and offers lists of “Major Plot Places,” “All Mentioned Places” in both alphabetical and frequency order, and autobiographical places mentioned by the author in al-Ghitani’s Mahfouz Dialogues

STY1 and STY2 promote the formation of apical tissues during Arabidopsis gynoecium development

Gynoecium ontogenesis in Arabidopsis is accomplished by the co-ordinated activity of genes that control patterning and the regional differentiation of tissues, and ultimately results in the formation of a basal ovary, a short style and an apical stigma. A transposon insertion in the STYLISH1 (STY1) gene results in gynoecia with aberrant style morphology, while an insertion mutation in the closely related STYLISH2 (STY2) gene has no visible effect on gynoecium development. However, sty1-1 sty2-1 double mutant plants exhibit an enhanced sty1-1 mutant phenotype and are characterized by a further reduction in the amount of stylar and stigmatic tissues and decreased proliferation of stylar xylem. These data imply that STY1 and STY2 are partially redundant and that both genes promote style and stigma formation and influence vascular development during Arabidopsis gynoecium development. Consistently, STY1 and STY2 are expressed in the apical parts of the developing gynoecium and ectopic expression of either STY1 or STY2 driven by the CaMV 35S promoter is sufficient to transform valve cells into style cells. STY1::GUS and STY2::GUS activity is detected in many other organs as well as the gynoecium, suggesting that STY1 and STY2 may have additional functions. This is supported by the sty1-1 sty2-1 double mutants producing rosette and cauline leaves with a higher degree of serration than wild-type leaves. STY1 and STY2 are members of a small gene family, and encode proteins with a RING finger-like motif. Double mutant analyses indicate that STY1 genetically interacts with SPATULA and possibly also with CRABS CLAW

The Personal Development Process of Employees in a Community Hospital

The purpose of this action research project was to assess and understand the existing Personal Development Process at CU and identify and mitigate the causes of the confusion and variations in implementation of this tool. A collaborative group utilized questionnaires, focus groups, and a pilot process to diagnose the extent of the problem. The collaborative group with the help of the organization\u27s employees designed and implemented interventions, and evaluated the project. The project results yielded an employee personal development tool which was used organization wide for 4 years

Effects of Elevated H\u3csup\u3e+\u3c/sup\u3e And P\u3csub\u3ei\u3c/sub\u3e on The Contractile Mechanics of Skeletal Muscle Fibres From Young and Old Men: Implications for Muscle Fatigue in Humans

The present study aimed to identify the mechanisms responsible for the loss in muscle power and increased fatigability with ageing by integrating measures of whole‐muscle function with single fibre contractile mechanics. After adjusting for the 22% smaller muscle mass in old (73–89 years, n = 6) compared to young men (20–29 years, n = 6), isometric torque and power output of the knee extensors were, respectively, 38% and 53% lower with age. Fatigability was ∼2.7‐fold greater with age and strongly associated with reductions in the electrically‐evoked contractile properties. To test whether cross‐bridge mechanisms could explain age‐related decrements in knee extensor function, we exposed myofibres (n = 254) from the vastus lateralis to conditions mimicking quiescent muscle and fatiguing levels of acidosis (H+) (pH 6.2) and inorganic phosphate (Pi) (30 mm). The fatigue‐mimicking condition caused marked reductions in force, shortening velocity and power and inhibited the low‐ to high‐force state of the cross‐bridge cycle, confirming findings from non‐human studies that these ions act synergistically to impair cross‐bridge function. Other than severe age‐related atrophy of fast fibres (−55%), contractile function and the depressive effects of the fatigue‐mimicking condition did not differ in fibres from young and old men. The selective loss of fast myosin heavy chain II muscle was strongly associated with the age‐related decrease in isometric torque (r = 0.785) and power (r = 0.861). These data suggest that the age‐related loss in muscle strength and power are primarily determined by the atrophy of fast fibres, but the age‐related increased fatigability cannot be explained by an increased sensitivity of the cross‐bridge to H+ and Pi

Quantitative evaluation of ontology design patterns for combining pathology and anatomy ontologies.

Data are increasingly annotated with multiple ontologies to capture rich information about the features of the subject under investigation. Analysis may be performed over each ontology separately, but recently there has been a move to combine multiple ontologies to provide more powerful analytical possibilities. However, it is often not clear how to combine ontologies or how to assess or evaluate the potential design patterns available. Here we use a large and well-characterized dataset of anatomic pathology descriptions from a major study of aging mice. We show how different design patterns based on the MPATH and MA ontologies provide orthogonal axes of analysis, and perform differently in over-representation and semantic similarity applications. We discuss how such a data-driven approach might be used generally to generate and evaluate ontology design patterns.National Institutes of Health (AG038070-05, for the Shock Aging Center) King Abdullah University of Science and Technology (KAUST) Office of Sponsored Research (OSR) under Award No. URF/1/3454-01-01 and FCC/1/1976-08-01. King Abdullah University of Science and Technology (KAUST) Office of Sponsored Research (OSR) under Award No. FCS/1/3657-02-0

Climate change, loss of (bio)diversity, natural ressource depletion, social marginalization etc: Our adaptation and mitigation contribution

The environmental and social challenges of the planet are a sad reality. Organic Agriculture advocates often espouse its contributions to mitigating the negative effects of farming. But mitigation alone is not enough. Farmers also need to adapt to a changed climate, reduced biodiversity and depleted resources as well as to an ever-changing socio-cultural environment

Organic Agriculture in the landscape of sustainability initiatives

Organic is not the only initiative with the aim of improving sustainability in agriculture. There is a wide array of approaches, perspectives, priorities and levels of ambition. Certain initiatives are seen as complimentary to Organic Agriculture and use it as a basis. Others are viewed as followers, competitors or – due to lower sustainability requirements – even as "greenwashers". As not all assessments of standards and impacts recognize a leading position for Organic farming, there is room for improvement

The mouse pathology ontology, MPATH; structure and applications

BACKGROUND: The capture and use of disease-related anatomic pathology data for both model organism phenotyping and human clinical practice requires a relatively simple nomenclature and coding system that can be integrated into data collection platforms (such as computerized medical record-keeping systems) to enable the pathologist to rapidly screen and accurately record observations. The MPATH ontology was originally constructed in 2,000 by a committee of pathologists for the annotation of rodent histopathology images, but is now widely used for coding and analysis of disease and phenotype data for rodents, humans and zebrafish. CONSTRUCTION AND CONTENT: MPATH is divided into two main branches describing pathological processes and structures based on traditional histopathological principles. It does not aim to include definitive diagnoses, which would generally be regarded as disease concepts. It contains 888 core pathology terms in an almost exclusively is_a hierarchy nine layers deep. Currently, 86% of the terms have textual definitions and contain relationships as well as logical axioms to other ontologies such the Gene Ontology. APPLICATION AND UTILITY: MPATH was originally devised for the annotation of histopathological images from mice but is now being used much more widely in the recording of diagnostic and phenotypic data from both mice and humans, and in the construction of logical definitions for phenotype and disease ontologies. We discuss the use of MPATH to generate cross-products with qualifiers derived from a subset of the Phenotype and Trait Ontology (PATO) and its application to large-scale high-throughput phenotyping studies. MPATH provides a largely species-agnostic ontology for the descriptions of anatomic pathology, which can be applied to most amniotes and is now finding extensive use in species other than mice. It enables investigators to interrogate large datasets at a variety of depths, use semantic analysis to identify the relations between diseases in different species and integrate pathology data with other data types, such as pharmacogenomics