5 research outputs found

    Polyphenolic Contents and Antioxidant Potential of Stem Bark Extracts from Jatropha curcas (Linn)

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    We assessed the polyphenolic contents and antioxidant potential of the aqueous, ethanol and methanol stem bark extracts of Jatropha curcas. The total phenol, flavonoids, flavonols and proanthocyanidin contents of the extracts were evaluated to determine their effect on the antioxidant property of this plant, using standard phytochemical methods. The antioxidant and free radical scavenging activity of ethanol, methanol and aqueous extracts of the plant were also assessed against 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), ferric reducing, nitric oxide (NO), superoxide anion, (O2−) and hydrogen peroxide (H2O2) using spectroscopic methods and results were compared with that of butylated hydroxyl toluene (BHT) and ascorbic acid as standards. The concentrations of different classes of phenolic compounds were higher in methanol and ethanol extracts compared to aqueous extracts. There was correlation between total phenol, total flavonoids, total flavonol and total proanthocyanidins (r = 0.996, 0.978, 0.908, and 0.985) respectively. There was correlations between the amount of phenolic compounds and percentage inhibition of DPPH radicals scavenging activity of the extract (r = 0.98). Findings from the present study indicated that J. curcas is a potential source of natural antioxidants and may be a good candidate for pharmaceutical plant based products

    Brain Tumor: An overview of the basic clinical manifestations and treatment

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    We review the basic clinical manifestation, diagnosis and management of brain tumor.&nbsp;Google search was done by using different terms associated with brain tumor and different databases were used, such as Google Scholar, Cochrane Database, and Science Direct etc.&nbsp;In spite of the fact that clinical manifestations fluctuate on the basis of category, magnitude and site of tumor, the most common clinical features reported are persistent headache, seizures, nausea and vomiting, loss of consciousness, dizziness, mood fluctuation, cognitive problems, visual defects, weakness of body parts, difficulty with speech and language, and hearing impairment. Apart from neurologic examination, diagnostic approaches include Computed Tomography (CT) scan, MRI and biopsy.&nbsp;Treatment strategies, determined by a variety of factors, include surgery, radiotherapy, chemotherapy and indicative therapy. This mini-review summarizes brain tumor biology as regards its classification, grading, risk factors, clinical presentation, diagnostic tools and treatment modalities.</p

    Response of lowland rice-ratooned rice-fluted pumpkin sequence to fertilizer in rainfed inland valley in derived savannah of Nigeria

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    Trial was carried out at Federal University of Agriculture, Abeokuta, Nigeria between 2010 and 2012 to determine response of lowland rice-ratooned rice-fluted pumpkin sequence to fertilizer. Experiment was laid out in Randomized Complete Block Design arranged in split-split plot in three replicates. Three rice genotypes constituted the main treatments sown in May and harvested in August. Split fertilizers application constituted sub-plot treatments were 90:45:45 (single dose), 45:22.5:22.5 &amp; 45:22.5:22.5 (1:1), 30:15:15 &amp; 60:30:30 (1:2) and 60:30:30 &amp; 30:15:15 (2:1) NPK ha-1 at tillering and heading. N-fertilizer rates were  sub-sub plot treatment and applied to ratooned ‘NERICA L-42’ had the tallest plants compare to others. ‘Ofada’ had the lowest number of days to 50 % flowering for main and ratooned rice, while ‘NERICA L-42’ had the highest number of days to 50 % heading. ‘NERICA L-41’ variety had the highest grain yield in main and ratooned rice. Based on this study, ‘NERICA L-41’ plus its ratooned rice obtained from single dose NPK and zero N-fertilizer plots produced grain yield of 4.69 t ha-1.</p
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