36 research outputs found

    Does severity of being small for gestational age in very low birth weight infants affect mortality?

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    Amaç: Gestasyon yaşına göre küçük (SGA) olmanın klasik tanımı, pretermlerde değişik derecelerde büyüme kısıtlılığının olması durumunda yetersiz değerlendirmeye sebep olabilir. Bu çalışmada çok düşük doğum ağırlıklı bebeklerde (ÇDDA) ılımlı ya da ciddi düzeyde SGA olmanın mortalite üzerine etkinliğinin araştırılması amaçlandı. Yöntem: Bu retrospektif çalışmaya 2013-2017 tarihlerinde hastanemizde doğan doğum ağırlığı 20 persentil olanlar AGA olarak gruplandırıldı. Persentil belirlemede Fenton büyüme eğrisi kullanıldı. Bulgular: Çalışmada SGA, M-SGA ve AGA grubuna sırası ile 34, 46 ve 631 bebek dahil edildi. Çalışmaya dahil edilen bebeklerden SGA olan grupta medyan doğum ağırlığı 660 g (560-720), M-SGA grubunda 800 g (720-870), AGA grubunda 1,080 g (920-1245) (p20 percentile were grouped as AGA. Fenton growth curve was used to determine percentile. Results: In the study, 34, 46 and 631 babies were included in the SGA, M-SGA and AGA groups, respectively. The median birth weight was 660 g (560-720) in the SGA group, 800 g (720-870) in the M-SGA group and 1080 g (920-1245) in the AGA group (p<0.001). Mortality rates were higher in SGA (44.1%) and M-SGA (15.2%) groups than in AGA (11.9%) groups (p<0.001). In logistic regression analysis, early neonatal sepsis [Odds ratio (OR): 2.5, 95% confidence interval (CI): 1.5-4.3], severe intraventricular bleeding (OR: 3.8, 95% CI: 2.08-6.77) and being SGA (OR: 7.08, 95% CI: 2.5-14.7) are found as independent risk factors for mortality. The presence of moderate SGA was not detected as an independent risk factor for mortality. Conclusion: SGA with accompanying prematurity involves more risk for morbidity and mortality. The presence of moderate SGA in very low birth weight infants may also increase mortality. Further studies are needed with new classifications prepared considering the severity of SGA

    Comparison of Mortality and Morbidities in Small and Appropriate For Gestational Age Preterm Infants

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    Aim:To compare morbidity and mortality in very low birth weight premature infants (VLBW) with small (SGA) and appropriate (AGA) for gestational age.Materials and Methods:The records of infants with VLBW who were followed up in our unit between 2013 and 2017 were retrospectively analyzed. SGA was defined as the birth weight being below the 10th percentile compared to the gestational week and the AGA birth weight being between the 10th and 90th percentile. A total of 96 SGA infants were identified as the study group and 204 AGA infants randomly selected and matched with the gestational week of the study group. Infants with major congenital anomalies and lack of data were excluded from the study.Results:The mean gestational age (28.3 ± 1.1–28.3 ± 1.2, p = 0.94) and birth weight (769 ± 144–1132 ± 190 g, <0.001, respectively) were in the SGA and AGA group respectively. Preeclampsia and cesarean delivery were significantly more frequent in the SGA group, whereas APGAR score was lower and CRIB score was significantly higher. The frequency of surfactant requirement, moderate-severe bronchopulmonary dysplasia, spontaneous intestinal perforation, periventricular leukomalacia, premature osteopenia, postnatal growth retardation, mortality and feeding intolerance were found to be significantly higher in SGA infants. Similarly, the duration of invasive ventilation and additional oxygen requirement and hospital stay were longer in SGA infants.Conclusion:The birth of premature babies with low birth weight according to gestational age causes premature morbidity and mortality

    Düşük BVDV prevalansı ile seyreden olguların izlenmesinde ekonomik bir izleme tekniği olarak havuzlama ve gerçek zamanlı RT-PZR

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    The aim of this study was to determine whether the use of pooled blood samples and real-time RT-PCR are feasible for detecting BVDV in viremic or PI animals. For this purpose, blood samples obtained from 2701 cattle, brought from 62 different farms, were used to test for the presence of bovine viral diarrhoea virus (BVDV) at the Veterinary Virology Department of Aksaray University Faculty of Veterinary Medicine. The sampling was done from all geographical regions in Turkey. Blood samples were pooled in groups of eight, creating a total of 342 pools. Each pool was checked for BVDV with a real-time RT-PCR test. BVDV nucleic acid was detected in 18 (5.26%) of a total of 342 pools. BVDV was detected in 18 of 62 farms. The most important result obtained from this study is that BVDV monitoring by pooling and real time RT-PCR can be done very economically when the disease prevalence is low (<10%). A risk/benefit estimation can be done for breeders who want to start vaccination programs.Bu çalışmanın amacı, havuzlanmış örnek ve gerçek zamanlı RT-PCR kullanımının viremik veya PI hayvanlarda BVDV'yi tespit etmek için uygun olup olmadığının belirlenmesidir. Bu amaçla, Aksaray Üniversitesi Veteriner Fakültesi Teşhis ve Analiz Laboratuvarına bovine viral diarrhoea virus (BVDV) enfeksiyonu açısından test edilmek üzere 62 farklı çiftlikten getirilen, 2701 sığırdan sağlanan kan örneği kullanıldı. Türkiye’nin tüm cografi bölgelerinden örnekleme yapıldı. Kan örnekleri sekizli gruplar halinde havuzlandı, toplam 342 adet havuz oluşturuldu. Her bir havuz BVDV yönünden real time RT-PCR testi ile kontrol edildi. Toplam 342 havuzdan 18 adedinde (%5,26) BVDV antijeni saptandı. Kontrol edilen 62 çiftliğin 18 tanesinde virus tespit edildi. Bu araştırmadan elde edilen en önemli sonuç, hastalık prevalansının düşük (<%10) olduğu durumlarda havuzlama ve real time RT-PCR ile BVDV izlemesinin çok ekonomik olarak yapılabileceğinin gösterilmesidir. Aşılama programlarına başlamak isteyen yetiştiriciler için bir risk / fayda tahmini yapılabilir

    Bornova İlçesi’nde dört okulda ergenlerde internet bağımlılığı ve güvenli internet kullanımının değerlendirilmesi

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    Aim: In this study it was aimed to evaluate the prevalence of Internet addiction in four pilot schools located in Bornova, one of İzmir’s most populated districts. Material and Methods: In this cross-sectional study the study sample comprised 1035 students in grade 6, 7, 9 and 10 of two state and two private schools located in Bornova district. The tools were “Internet addiction scale” developed by Günüç and Kayri in 2009 and a personal questionnaire form. Results: We reached 685 of 1035 students in the study sample. Twenty-four students who did not fill the questionnaire properly were excluded and a total of 661 students (63.9%) were included in the analysis. According to Internet addiction scale, 37.4% (n=247) were not Internet addict while 36.9% (n=244) were in the risk group and 25.7% (n=170) were Internet addict. Internet addiction was significantly associated with safe Internet use (x2=9,013; p=0,011), daily personnel computer game playing (x2=76,556; p=0,000), watching television (x2=11,859; p=0,003), Internet connection time (x2=61,787; p=0,000) ), informing the student at home about internet (x2 =19.386; p0,001) and age for starting Internet use (x2=23,360; p=0,000). Conclusion: These data suggest that a substantial part of the students is Internet addict. Hence, further interventional studies are needed for prevention.Amaç: Bu çalışmada İzmir?in nüfusu en büyük ilçelerinden Bornova İlçesi?nde belirlenen dört pilot okulda internet bağımlılığı prevalansının değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Bu kesitsel çalışmada araştırma grubunu Bornova ilçesindeki iki devlet ve iki özel okulun 6., 7., 9. ve 10. sınıflarındaki 1035 öğrenci oluşturdu. Veri toplama aracı olarak, Günüç ve Kayri?nin 2009 yılında geliştirdiği “internet bağımlılık ölçeği” ve kişisel anket formu kullanıldı. Bulgular: Çalışma grubundaki 1035 öğrencinin 685?ine ulaşıldı. Formları uygun şekilde doldurmayan 24 öğrenci çalışma dışında bırakıldı; %63,9?u (n=661) analize alındı. İnternet bağımlılık ölçeğine göre öğrencilerin %37,4?ü (n=247) internet bağımlısı değilken, %36,9?u (n=244) risk grubundaydı ve %25,7?si (n=170) ise internet bağımlısıydı. İnternet bağımlılık durumları ile güvenli internet kullanma (x2=9,013; p=0,011), günlük bilgisayar oyunu oynama (x2=76,556; p=0,000), televizyon izleme (x2=11,859; p=0,003), öğrencinin internet hakkında evde bilgilendirilmesi (x2 =19.386; p0,001) ve internete bağlanma süresi (x2=61,787; p0,000), internet kullanmaya başlama yaşı (x2=23,360; p0,000) arasında istatistiksel olarak anlamlı ilişki saptandı. Sonuç: Verilerimiz öğrencilerin azımsanmayacak kısmının “internet bağımlısı” olduğunu göstermektedir. Bu konuda daha ileri araştırmalar ve koruyucu çalışmalar yapılmasında fayda vardır

    A successful treatment approach in 2 patients with type 1 plasminogen deficiency: Intratracheal application of fresh frozen plasma and tissue plasminogen activator

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    BACKGROUND: Respiratory system involvement is common in congenital plasminogen deficiency. Although many treatment approaches have been tried, there is still no definitive treatment for respiratory system involvement. OBSERVATIONS: We report 2 congenital plasminogen deficiency cases, who presented with severe respiratory symptoms, for whom a novel treatment modality was tried. After intravenous administration of FFP (fresh frozen plasma), tissue plasminogen activator and FFP were administered intratracheally, and respiratory system findings improved. CONCLUSIONS: Intratracheal administration of tissue plasminogen activator and FFP is an available treatment modality for patients with lung involvement. Fibrin plaques should be carefully removed and new lesion formation should be prevented
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