Identification of viscoplastic parameters and characterization of Lüders behaviour using digital image correlation and the virtual fields method

In this study, tensile loading experiments are performed on notched steel bars at an average applied strain rate of 1s-1. Displacement fields are measured across the specimen by coupling digital image correlation (DIC) with imaging using high speed CCD cameras (4796 fps). Results from the experiments indicate the presence of local strain rates ranging from 0.1 to 10s-1 in the notched specimens. The heterogeneity of the strain rate fields provides suitable conditions for determining simultaneously all the elasto-visco-plastic constitutive parameters governing the material behavior. For that, the whole stress fields are reconstructed in the specimen using the full-field deformation measurements. This reconstruction is repeated with different constitutive parameters until the average stress in the specimen matches the one measured with the load cell response. Perzyna’s model is firstly considered for the reconstruction of stresses but it is shown to be unsuited for providing the drop in the average stress that is systematically detected at the onset of plasticity by the load cell. This drop is attributed to the sudden occurrence of plasticity in the material due to Lüders effect. A modified model for elasto-visco-plasticity taking account of Lüders behavior in the material is considered afterwards. It yields a better agreement between the reconstructed stresses and the load cell response, and a more accurate identification of the parameters driving the visco-plastic model. Eventually, it is shown how to use DIC measurements for replacing the load cell measurements when the transient effects in the test reach the resonance frequency of the load cel

X-ray emission of contact binary variables within 1 kpc

By assembling the largest sample to date of X-ray emitting EW-type binaries (EWXs), we carried out correlation analyses for the X-ray luminosity log$L_{\textrm{X}}$, and X-ray activity level log($L_{\textrm{X}}$/$L_{\textrm{bol}}$) versus the orbital period $P$ and effective temperature $T_{\rm eff}$. We find strong $P$-log$L_{\textrm{X}}$ and $P$-log($L_{\textrm{X}}$/$L_{\textrm{bol}}$) correlations for EWXs with $P$ < 0.44 days and we provide the linear parametrizations for these relations, on the basis of which the orbital period can be treated as a good predictor for log$L_{\textrm{X}}$ and log($L_{\textrm{X}}$/$L_{\textrm{bol}}$). The aforementioned binary stellar parameters are all correlated with log$L_{\textrm{X}}$, while only $T_{\rm eff}$ exhibits a strong correlation with log($L_{\textrm{X}}$/$L_{\textrm{bol}}$). Then, EWXs with higher temperature show lower X-ray activity level, which could indicate the thinning of the convective area related to the magnetic dynamo mechanism. The total X-ray luminosity of an EWX is essentially consistent with that of an X-ray saturated main sequence star with the same mass as its primary, which may imply that the primary star dominates the X-ray emission. The monotonically decreasing $P$-log($L_{\textrm{X}}$/$L_{\textrm{bol}}$) relation and the short orbital periods indicate that EWXs could all be in the X-ray saturated state, and they may inherit the changing trend of the saturated X-ray luminosities along with the mass shown by single stars. For EWXs, the orbital period, mass, and effective temperature increase in concordance. We demonstrate that the period $P=0.44$ days corresponds to the primary mass of $\sim1.1 \rm M_\odot$, beyond which the saturated X-ray luminosity of single stars will not continue to increase with mass. This explains the break in the positive $P$-log$L_{\textrm{X}}$ relation for EWXs with $P>0.44$ days.Comment: 16 pages, 7 figures and 8 tables; accepted for publication in A&

Decision Tree Classification Model In Water Supply Network

With the service life of water supply network (WSN) growth, the growing phenomenon of aging pipe network has become exceedingly serious. As urban water supply network is hidden underground asset, it is difficult for monitoring staff to make a direct classification towards the faults of pipe network by means of the modern detecting technology. In this paper, based on the basic property data (e.g. diameter, material, pressure, distance to pump, distance to tank, load, etc.) of water supply network, decision tree algorithm (C4.5) has been carried out to classify the specific situation of water supply pipeline. Part of the historical data was used to establish a decision tree classification model, and the remaining historical data was used to validate this established model. Adopting statistical methods were used to access the decision tree model including basic statistical method, Receiver Operating Characteristic (ROC) and Recall-Precision Curves (RPC). These methods has been successfully used to assess the accuracy of this established classification model of water pipe network. The purpose of classification model was to classify the specific condition of water pipe network. It is important to maintain the pipeline according to the classification results including asset unserviceable (AU), near perfect condition (NPC) and serious deterioration (SD). Finally, this research focused on pipe classification which plays a significant role in maintaining water supply networks in the future

Nitric Oxide, NOC-12, and S -Nitrosoglutathione Modulate the Skeletal Muscle Calcium Release Channel/Ryanodine Receptor by Different Mechanisms: AN ALLOSTERIC FUNCTION FOR O2INS-NITROSYLATION OF THE CHANNEL

The skeletal muscle Ca(2+) release channel/ryanodine receptor (RyR1) contains approximately 50 thiols per subunit. These thiols have been grouped according to their reactivity/responsiveness toward NO, O(2), and glutathione, but the molecular mechanism enabling redox active molecules to modulate channel activity is poorly understood. In the case of NO, very low concentrations (submicromolar) activate RyR1 by S-nitrosylation of a single cysteine residue (Cys-3635), which resides within a calmodulin binding domain. S-Nitrosylation of Cys-3635 only takes place at physiological tissue O(2) tension (pO(2); i.e. approximately 10 mm Hg) but not at pO(2) approximately 150 mm Hg. Two explanations have been offered for the loss of RyR1 responsiveness to NO at ambient pO(2), i.e. Cys-3635 is oxidized by O(2) versus O(2) subserves an allosteric function (Eu, J. P., Sun, J. H., Xu, L., Stamler, J. S., and Meissner, G. (2000) Cell 102, 499-509). Here we report that the NO donors NOC-12 and S-nitrosoglutathione both activate RyR1 by release of NO but do so independently of pO(2). Moreover, NOC-12 activates the channel by S-nitrosylation of Cys-3635 and thereby reverses channel inhibition by calmodulin. In contrast, S-nitrosoglutathione activates RyR1 by oxidation and S-nitrosylation of thiols other than Cys-3635 (and calmodulin is not involved). Our results suggest that the effect of pO(2) on RyR1 S-nitrosylation is exerted through an allosteric mechanism

Classes of Thiols That Influence the Activity of the Skeletal Muscle Calcium Release Channel

The skeletal muscle Ca(2+) release channel/ryanodine receptor (RyR1) is a prototypic redox-responsive ion channel. Nearly half of the 101 cysteines per RyR1 subunit are kept in a reduced (free thiol) state under conditions comparable with resting muscle. Here we assessed the effects of physiological determinants of cellular redox state (oxygen tension, reduced (GSH) or oxidized (GSSG) glutathione, and NO/O(2) (released by 3-morpholinosydnonimine)) on RyR1 redox state and activity. Oxidation of approximately 10 RyR1 thiols (from approximately 48 to approximately 38 thiols/RyR1 subunit) had little effect on channel activity. Channel activity increased reversibly as the number of thiols was further reduced to approximately 23/subunit, whereas more extensive oxidation (to approximately 13 thiols/subunit) inactivated the channel irreversibly. Neither S-nitrosylation nor tyrosine nitration contributed to these effects. The results identify at least three functional classes of RyR1 thiols and suggest that 1) the channel may be protected from oxidation by a large reservoir of functionally inert thiols, 2) the channel may be designed to respond to moderate oxidative stress by a change in activation setpoint, and 3) the channel is susceptible to oxidative injury under more extensive conditions