160 research outputs found
Wage Structure Determinants and Gender Pay Gap among Wage Earners: from Mean to Overall Log Wage Distributional Decomposition
This study comprehensively investigates the wage structure determinants and gender pay gap in Korea. Using 2014 Korean Labor and Income Panel Study (KLIPS) data, we find that individual characteristics exhibit significant differences across the distribution and that magnitude and significance differ according to gender. Findings suggest that returns to education are high for women and experience is influential only for women at the upper wage distribution. By applying vigorous counterfactual decomposition method, we find large returns on characteristic differentials by gender, especially for lowly educated women. A strong glass ceiling effect in Korea is obtained, and the integrative effect is composed of the continuously increasing composition effect and N-shaped (i.e., low at both ends) structure effect. In particular, most of the explained differentials are attributable to the differences of experience. The high returns on education for women are beneficial for reducing discrimination (unexplained or structure effect)
PDMSkin – On-Skin Gestures with Printable Ultra-Stretchable Soft Electronic Second Skin
Innovative enabling technologies are key drivers of human augmentation. In this paper, we explore a new, conductive, and configurable material made from Polydimethylsiloxane (PDMS) that is capillary doped with silver particles (Ag) using an immiscible secondary fluid to build ultra-stretchable, soft electronics. Bonding silver particles directly with PDMS enables inherently stretchable Ag-PDMS circuits. Compared to previous work, the reduced silver consumption creates significant advantages, e.g., better stretchability and lower costs. The secondary fluid ensures self-assembling conductivity networks. Sensors are 3D-printed ultra-thin (200%. Therefore, printed circuits can attach tightly onto the body. Due to biocompatibility, devices can be implanted (e.g., open wounds treatment). We present a proof of concept on-skin interface that uses the new material to provide six distinct input gestures. Our quantitative evaluation with ten participants shows that we can successfully classify the gestures with a low spatial-resolution circuit. With few training data and a gradient boosting classifier, we yield 83% overall accuracy. Our qualitative material study with twelve participants shows that usability and comfort are well perceived; however, the smooth but easy to adapt surface does not feel tissue-equivalent. For future work, the new material will likely serve to build robust and skin-like electronics
Optical property of few-mode fiber with non-uniform refractive index for cylindrical vector beam generation
This paper investigates optical properties of few-mode fiber with non-uniform refractive index, namely: the few mode fiber with U-shape refractive index and the two-mode and four-mode few-mode fiber with bent radius. Finite element method is used to analyze the mode distributions based on their non-uniform refractive index. Effective mode control can be achieved through these few mode fibers to achieve vector beam generation. Finally, reflection spectra of a few-mode fiber Bragg grating are calculated theoretically and then measured under different bending conditions. Experimental results are in good accordance with the theoretical ones. These few mode fibers show potential applications in generation of cylindrical vector beam both for optical lasing and sensing systems
FLECTILE: 3D-printable soft actuators for wearable computing
Rapid prototyping and fast manufacturing processes are critical drivers for implementing wearable devices. This paper shows an exemplary method for building flexible, fully elastomeric, vibrotactile electromagnetic actuators based on the Lorentz force law. This paper also introduces the design parameters required for well-functioning actuators and studies the properties of such actuators. The crucial element of the actuator is a helical planer coil manufactured from "capillary" silver TPU (Thermoplastic polyurethane), an ultra-stretchable conductor. This paper leverages the novel material to manufacture soft vibration actuators in fewer and simpler steps than previous approaches. Best practices and procedures for building a wearable actuator are reported. We show that the dimension of the actuators are easily configurable and can be printed in batch-size-one using 3D printing. Actuators can be attached directly to the skin as all the components of FLECTILE are made from biocompatible polymers. Tests on the driving properties have confirmed that the actuator could reach a broad scope of frequency up to 200 Hz with a small voltage (5 V) required. A user study showed that vibrations of the actuator are well perceivable by six study participants under an observing, hovering, and resting condition
Microstructure and mechanical properties of double-wire + arc additively manufactured Al-Cu-Mg alloys
As the properties of wire + arc additively manufactured Al-6.3Cu alloy cannot meet the applying requirements, a double-wire + arc additive manufacturing system was built to add magnesium into Al-Cu deposits for higher mechanical properties. Two commercial binary wires aluminum-copper ER2319 and aluminum-magnesium ER5087 were chosen as the filler metal to build Al-Cu-Mg components with different compositions by adjusting the wire feed speed. The microstructure and morphology of thin wall samples were characterized by optical micrographs (OM), X-ray diffraction (XRD) and scanning electron microscopy (SEM). The Vickers hardness and tensile properties were investigated. The microstructure of Al-Cu-Mg deposits was mainly composed of coarse columnar grains and fine equiaxed grains with non-uniformly distributing characteristics. With higher Cu but lower Mg content, the strengthen phase turned to Al2Cu + Al2CuMg from Al2CuMg, and the micro hardness presented an increasing trend. The isotropic characteristics of ultimate tensile strength (UTS), yield strength (YS) and elongation were revealed in these samples. The UTS was about 280 ± 5 MPa both in horizontal and vertical directions for all samples. The YS showed an increasing trend from 156 MPa to 187 MPa with the same content trend, while elongation decreased from 8.2% to 6%. The fractographs exhibited typical brittle fracture characteristics
A comparative study of additively manufactured thin wall and block structure with Al-6.3% Cu alloy using cold metal transfer process
In order to build a better understanding of the relationship between depositing mode and porosity, microstructure, and properties in wire + arc additive manufacturing (WAAM) 2319-Al components, several Al-6.3%Cu deposits were produced by WAAM technique with cold metal transfer (CMT) variants, pulsed CMT (CMT-P) and advanced CMT (CMT-ADV). Thin walls and blocks were selected as the depositing paths to make WAAM samples. Porosity, microstructure and micro hardness of these WAAM samples were investigated. Compared with CMT-P and thin wall mode, CMT-ADV and block process can effectively reduce the pores in WAAM aluminum alloy. The microstructure varied with different depositing paths and CMT variants. The micro hardness value of thin wall samples was around 75 HV from the bottom to the middle, and gradually decreased toward the top. Meanwhile, the micro hardness value ranged around 72–77 HV, and varied periodically in block samples. The variation in micro hardness is consistent with standard microstructure characteristics
An injection-locked single-longitudinal-mode fiber ring laser with cylindrical vector beam emission
We demonstrate a fiber ring laser with narrow bandwidth single-longitudinal-mode cylindrical vector beam (CVB) output at C-band wavelength range for the first time to the best of our knowledge. A step index two-mode fiber Bragg grating is used as a transverse mode selector for CVB generation, while both the injection-locking technique and narrow bandwidth of the fiber Bragg grating lead to single-longitudinal-mode operation. The 3-dB bandwidth of the laser output is measured to be 60 dB. Mode distribution and optical spectra of few-mode fibers with periodic modulated refractive index profile, namely the few-mode fiber Bragg gratings with bent radius, are investigated theoretically and experimentally, which provide a comprehensive exploration of CVB's generation
Cryptotanshinone Attenuates Oxygen-Glucose Deprivation/ Recovery-Induced Injury in an in vitro Model of Neurovascular Unit
Cryptotanshinone (CTs), an active component isolated from the root of Salvia miltiorrhiza (SM), has been shown to exert potent neuroprotective property. We here established an oxygen-glucose deprivation/recovery (OGD/R)-injured Neurovascular Unit (NVU) model in vitro to observe the neuroprotective effects of CTs on cerebral ischemia/reperfusion injury (CIRI), and explore the underlying mechanisms. CTs was observed to significantly inhibit the OGD/R-induced neuronal apoptosis, and decease the activation of Caspase-3 and the degradation of poly-ADP-ribose polymerase (PARP), as well as the increase of Bax/Bcl-2 ratio in neurons under OGD/R condition. The inhibitory effects of CTs on neuron apoptosis were associated with the blocking of mitogen-activated protein kinase (MAPK) signaling pathway. CTs also remarkably ameliorated OGD/R-induced reduction of transepithelial electrical resistance (TEER) values and the increase of transendothelial permeability coefficient (Pe) of sodium fluorescein (SF) by upregulating the expression of ZO-1, Claudin-5, and Occludin in brain microvascular endothelial cells (BMECs), which might be related to the down-regulation of matrix metalloproteinase (MMP)-9 expression. Based on these findings, CTs may play a neuroprotective role in OGD/R injure in NVU models in vitro by inhibiting cell apoptosis and alleviating the damage of blood-brain barrier (BBB)
Metadata Service to Enable Display of Rich Artifacts in Machine Learning Pipelines
Cloud-based machine learning (ML) platforms enable ML practitioners to build, rebuild, and serve multiple machine learning models in production environments. Proper ML metadata tracking and management is important to enable large-scale experimentation and to provide traceability and verifiability for modern production ML. This disclosure describes a ML metadata service to manage the lifecycle of metadata consumed and produced by ML pipelines. The ML metadata service enables logging detailed metadata as artifacts, capturing metadata as typed artifacts, and capturing a ML pipeline in an intuitive workflow graph. The metadata service enables provision of a ML dashboard that displays visualizations of a ML workflow along with the relevant metadata for each type of entity and supports queries for models and/or datasets that meet specific criteria
Loss of Conformational Stability in Calmodulin upon Methionine Oxidation
We have used electrospray ionization mass spectrometry (ESI-MS), circular dichroism (CD), and fluorescence spectroscopy to investigate the secondary and tertiary structural consequences that result from oxidative modification of methionine residues in wheat germ calmodulin (CaM), and prevent activation of the plasma membrane Ca-ATPase. Using ESI-MS, we have measured rates of modification and molecular mass distributions of oxidatively modified CaM species (CaMox) resulting from exposure to H2O2. From these rates, we find that oxidative modification of methionine to the corresponding methionine sulfoxide does not predispose CaM to further oxidative modification. These results indicate that methionine oxidation results in no large-scale alterations in the tertiary structure of CaMox, because the rates of oxidative modification of individual methionines are directly related to their solvent exposure. Likewise, CD measurements indicate that methionine oxidation results in little change in the apparent α-helical content at 28°C, and only a small (0.3 ± 0.1 kcal mol−1) decrease in thermal stability, suggesting the disruption of a limited number of specific noncovalent interactions. Fluorescence lifetime, anisotropy, and quenching measurements of N-(1-pyrenyl)-maleimide (PMal) covalently bound to Cys26 indicate local structural changes around PMal in the amino-terminal domain in response to oxidative modification of methionine residues in the carboxyl-terminal domain. Because the opposing globular domains remain spatially distant in both native and oxidatively modified CaM, the oxidative modification of methionines in the carboxyl-terminal domain are suggested to modify the conformation of the amino-terminal domain through alterations in the structural features involving the interdomain central helix. The structural basis for the linkage between oxidative modification and these global conformational changes is discussed in terms of possible alterations in specific noncovalent interactions that have previously been suggested to stabilize the central helix in CaM
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