Hybrid ECAL: Optimization and Related Developments

Hybrid ECAL is a cost-conscious option of electromagnetic calorimeter (ECAL) for particle flow calorimetry to be used in a detector of International Linear Collider (ILC). It is a combination of silicon-tungsten ECAL, which realizes high granularity and robust measurement of electromagnetic shower, and scintillator-tungsten ECAL, which gives affordable cost with similar performance to silicon. Optimization and a data acquisition trial in a test bench for the hybrid ECAL are described in this article.Comment: 7 pages, 4 figures, Talk presented at the International Workshop on Future Linear Colliders (LCWS14), Belgrade, Serbia, 6-10 October 201

Combined operations and the European theatre during the Nine Years' War, 1688-97

This is the author's PDF version of an article published in Historical research© 2005. The definitive version is available at www.blackwell-synergy.com.This article discusses the strategic and operational purpose of England's combined army-navy operations within the European theatre during the Nine Years' War, 1688-97. Specifically, the historical consensus that these operations were simply a compromise product of the contemporary political discourse, and consistently suffered from poor preparation and implementation, is reassessed. In so doing, the article considers the combined service descents planned and executed against the northern French coastline between 1691 and 1694, including in particular the renowned operation at Brest in June 1694, and also those operations undertaken by Admiral Russell's Mediterranean fleet in 1695.This article was submitted to the RAE2008 for the University of Chester - History

An aerogel Cherenkov detector for multi-GeV photon detection with low sensitivity to neutrons

We describe a novel photon detector which operates under an intense flux of neutrons. It is composed of lead-aerogel sandwich counter modules. Its salient features are high photon detection efficiency and blindness to neutrons. As a result of Monte Carlo (MC) simulations, the efficiency for photons with the energy larger than 1 GeV is expected to be higher than 99.5% and that for 2 GeV/$c$ neutrons less than 1%. The performance on the photon detection under such a large flux of neutrons was measured for a part of the detector. It was confirmed that the efficiency to photons with the energy $>$1 GeV was consistent with the MC expectation within 8.2% uncertainty.Comment: 16 pages, 16 figures, submitted to Prog. Theor. Exp. Phy

Abnormal systolic blood pressure response during exercise is related to subendocardial hypoperfusion detected by exercise 201Tl myocardial scintigraphy in patient with hypertrophic cardiomyopathy

Balcells, EugèniaPla general, d'alguns dels elements que formen la taula periòdica. Cadascun dels 112 elements és representat pel seu espectre de color. Es van produir diverses còpies de l'obra, aquesta està a la Biblioteca de la Facultat de Química

Lipoprotein biosynthesis in the larvae of the tobacco hornworm, Manduca-sexta

Lipoprotein biosynthesis in larvae of the tobacco hornworm (Manduca sexta) was investigated. By immunoblotting, it was shown that the apoproteins are present in the fat body, but not in the midgut. Fat body incubated in vitro with [35S]methionine secreted labeled apoproteins. However, when the density of the secreted particle was determined, it was found at 1.24-1.28 g/ml instead of 1.15 g/ml, which is the density of the circulating lipoprotein. Lipid analysis of immunoprecipitated lipoprotein secreted by the fat body showed a phospholipid/diacylglycerol ratio of 8.3 rather than 0.9, the ratio found in the circulating lipoprotein. When labeled oleic acid or triolein was fed to larvae, it was found that greater than 98% of the label in the circulating lipoprotein was in diacylglycerol. In studies using animals raised on a fat-free diet, it was shown that the circulating lipoprotein has properties comparable to those of the material secreted in vitro by the fat body and that this diacylglycerol-poor particle can be converted to the normal lipoprotein by feeding a bolus of triolein. These data support the hypothesis that the fat body makes and secretes a "nascent" lipoprotein which contains apoproteins and phospholipid, but is devoid of diacylglycerol. The diacylglycerol is then picked up from the midgut to complete assembly of the mature circulating lipoprotein

Search for Dark Photon Dark Matter in the Mass Range 41--74 μeV\mu\mathrm{eV} using Millimeter-Wave Receiver and Radioshielding Box

Dark photons have been considered potential candidates for dark matter. The dark photon dark matter (DPDM) has a mass and interacts with electromagnetic fields via kinetic mixing with a coupling constant of $\chi$. Thus, DPDMs are converted into ordinary photons at metal surfaces. Using a millimeter-wave receiver set in a radioshielding box, we performed experiments to detect the conversion photons from the DPDM in the frequency range 10--18 GHz, which corresponds to a mass range 41--74 $\mu\mathrm{eV}$. We found no conversion photon signal in this range and set the upper limits to $\chi < (0.5\text{--}3.9) \times 10^{-10}$ at a 95% confidence level.Comment: 8 pages, 14 figure

Pharmacological And Genetic Reversal Of Age-Dependent Cognitive Deficits Attributable To Decreased Presenilin Function

Alzheimer\u27s disease (AD) is the leading cause of cognitive loss and neurodegeneration in the developed world. Although its genetic and environmental causes are not generally known, familial forms of the disease (FAD) are attributable to mutations in a single copy of the Presenilin (PS) and amyloid precursor protein genes. The dominant inheritance pattern of FAD indicates that it may be attributable to gain or change of function mutations. Studies of FAD-linked forms of presenilin (psn) in model organisms, however, indicate that they are loss of function, leading to the possibility that a reduction in PS activity might contribute to FAD and that proper psn levels are important for maintaining normal cognition throughout life. To explore this issue further, we have tested the effect of reducing psn activity during aging in Drosophila melanogaster males. We have found that flies in which the dosage of psn function is reduced by 50% display age-onset impairments in learning and memory. Treatment with metabotropic glutamate receptor (mGluR) antagonists or lithium during the aging process prevented the onset of these deficits, and treatment of aged flies reversed the age-dependent deficits. Genetic reduction of Drosophila metabotropic glutamate receptor (DmGluRA), the inositol trisphosphate receptor (InsP(3)R), or inositol polyphosphate 1-phosphatase also prevented these age-onset cognitive deficits. These findings suggest that reduced psn activity may contribute to the age-onset cognitive loss observed with FAD. They also indicate that enhanced mGluR signaling and calcium release regulated by InsP(3)R as underlying causes of the age-dependent cognitive phenotypes observed when psn activity is reduced