Determining the radiation use efficiency of potato using sunshine hour data: a simple and costless approach

Aim of study: Radiation parameters and photoperiod influence potato biomass and tuber yield significantly. Lack of instrument facilities in developing countries is the main hindrance to estimate global solar radiation (GSR) and radiation use efficiency (RUE). Considering these facts, an experiment was conducted to estimate light extinction coefficient (K) and RUE using a simple but indirect approach that can be implied in any location lacking sophisticated instruments.Area of study: Field experiments were conducted in Kalyani, West Bengal, representing the Indo-Gangetic Plains.Material and methods: Angstrom-Prescott (A-P) equation was used to calculate GSR. The experiment was laid out in a split-plot design with three dates of planting (DOP), 15th Nov, 29th Nov and 13th Dec, as main plot treatment and three potato cultivars (ˈKufri Suryaˈ, ˈKufri Chandramukhiˈ and ˈKufri Jyotiˈ) as sub-plot treatment. Leaf area indices and K values were used to determine intercepted PAR (IPAR) as well as RUE.Main results: The cumulative IPAR from emergence to harvest ranged 246-429 MJ m-2 depending on planting time and varieties. Irrespective of DOPs, the highest mean RUE (4.19 g MJ-1) was calculated in ˈKufri Chandramukhiˈ, showing that it used the radiation more efficiently that the other two cultivars (ˈKufri Suryaˈ= 3.75 g MJ-1 and ˈKufri Jyotiˈ= 3.14 g MJ-1).Research highlights: Statistical indices confirmed that the A-P model can be reliably used in the study region for estimation of GSR. This simple way to estimating RUE using bright sunshine hours data can be used in developing countries, where costly radiation instruments are not available

SYNTHESIS & IN-VITRO PROTEIN DENATURATION SCREENING OF 2-[(1, 5-DISUBSTITUTEDPHENYL-4,5-DIHYDRO-1H-PYRAZOL-3-YL)OXY]BENZOIC ACID DERIVATIVES

Abstract Novel 2-[(1,5-diphenyl-4,5-dihydro-1H-pyrazol-3-yl)oxy]benzoic acid (2a) & 2-[5-(2-hydroxyphenyl)-1-Phenyl-4,5-dihydro-1H-pyrazol-3-yl]benzoic acid (2b) were produced and examined for their in-vitro protein denaturation activities. It was discovered that compound 2b showed promise and had more potency than acetylsalicylic acid (NSAID) in inhibiting denaturation of bovine serum albumin. Docking research also supports this. The compound 2b has the highest docking scores with COX1(PDB ID 3N8Z), COX2 (PDB ID 4PH9), and TNF (PDB ID 2AZ5), respectively, of Etotal -233.75, -256.48, and -255.83. TLC and elemental tests were used to determine the compounds' purity. All of the generated molecules' analytical and spectral data (1H NMR, FTIR, and MS) were entirely consistent with the proposed structures

Comparative evaluation of facial parameters and symmetry - A hospital based study in Bhubaneswar

The study focuses on measuring various facial parameters and their relationships in individuals seeking orthodontic care. Materials and methods: The researchers conducted a study in Bhubaneswar, India, involving 102 subjects (47 males and 55 females) aged 20 to 45 years. They used descriptive and statistical analyses to examine measurements such as distances between inner canthi of eyes, eye widths, interpupillary line width, and nasal width. Result: The study revealed sexual dimorphism in some measurements, indicating differences between males and females. The distance between inner canthus of eye (p-value - 0.0528 ) showed that males have larger width compared to females, width of left eye ( p-value - 0.0055 ) and width of right eye ( p-value - 0.0706 ) showed that males have wider eyes than females. Inter pupillary line width (p-value 0.0046 ) indicates that males have larger pupil gap compared to females. Nasal width (p-value 0.0766 ) indicates wider nose in males compared to females. The research is conducted on a sample of residents from Bhubaneswar, India, within a specific age range, and includes measurements related to eye width, nasal width, and interpupillary line width. Clinical significance: The abstract also references previous studies and their findings in the field of orthodontics, including discussions about the impact of orthodontic tooth movement on the soft tissue profile and the need for further research to comprehensively understand facial form. Conclusion: The abstract concludes by emphasizing the importance of facial esthetics in orthodontic treatment and the need for more studies to investigate angular and facial features

Recent insights of obesity-induced gut and adipose tissue dysbiosis in type 2 diabetes

An imbalance in microbial homeostasis, referred to as dysbiosis, is critically associated with the progression of obesity-induced metabolic disorders including type 2 diabetes (T2D). Alteration in gut microbial diversity and the abundance of pathogenic bacteria disrupt metabolic homeostasis and potentiate chronic inflammation, due to intestinal leakage or release of a diverse range of microbial metabolites. The obesity-associated shifts in gut microbial diversity worsen the triglyceride and cholesterol level that regulates adipogenesis, lipolysis, and fatty acid oxidation. Moreover, an intricate interaction of the gut-brain axis coupled with the altered microbiome profile and microbiome-derived metabolites disrupt bidirectional communication for instigating insulin resistance. Furthermore, a distinct microbial community within visceral adipose tissue is associated with its dysfunction in obese T2D individuals. The specific bacterial signature was found in the mesenteric adipose tissue of T2D patients. Recently, it has been shown that in Crohn’s disease, the gut-derived bacterium Clostridium innocuum translocated to the mesenteric adipose tissue and modulates its function by inducing M2 macrophage polarization, increasing adipogenesis, and promoting microbial surveillance. Considering these facts, modulation of microbiota in the gut and adipose tissue could serve as one of the contemporary approaches to manage T2D by using prebiotics, probiotics, or faecal microbial transplantation. Altogether, this review consolidates the current knowledge on gut and adipose tissue dysbiosis and its role in the development and progression of obesity-induced T2D. It emphasizes the significance of the gut microbiota and its metabolites as well as the alteration of adipose tissue microbiome profile for promoting adipose tissue dysfunction, and identifying novel therapeutic strategies, providing valuable insights and directions for future research and potential clinical interventions

Digital Inclusion of the Farming Sector Using Drone Technology

Agriculture continues to be the primary source of income for most rural people in the developing economy. The world’s economy is also strongly reliant on agricultural products, which accounts for a large number of its exports. Despite its growing importance, agriculture is still lagging behind to meet the demands due to crop failure caused by bad weather conditions and unmanaged insect problems. As a result, the quality and quantity of agricultural products are occasionally affected to reduce the farm income. Crop failure could be predicted ahead of time and preventative measures could be taken through a combination of conventional farming practices with contemporary technologies such as agri-drones to address the difficulties plaguing the agricultural sectors. Drones are actually unmanned aerial vehicles that are used for imaging, soil and crop surveillance, and a variety of other purposes in agricultural sectors. Drone technology is now becoming an emerging technology for large-scale applications in agriculture. Although the technology is still in its infancy in developing nations, numerous research and businesses are working to make it easily accessible to the farming community to boost the agricultural productivity

Quantification of Alectinib in spiked rabbit plasma using liquid chromatography- electro spray ionization-tandem mass spectrophotometry: An application to pharmacokinetic study

The current technique was developed to estimate the amount of alectinib present in spiked rabbit plasma using liquid chromatographic mass spectrometry. The liquid-liquid extraction method was used, and chromatographic separation was carried out on a C18 (4.6mm id x 50mm) analytical column with a mobile phase consisting of acetonitrile and water with 0.1% formic acid at a volume ratio of 75:25. Alectinib's product m/z +483.2 (parent) 396.1 (product) and the internal standard m/z +447.5 (parent) 380.3 (product) were both obtained using positive ion mode. The calibration curve was linear from 0.5 to 600 ng/ml. The percentage extraction recovery (98.15% → 98.86%), demonstrated excellent matrix and analyte selectivity (% interference = 0), and satisfactory stability study results in all types (% nominal 94.94% → 99.63%). The intra and interday accuracy with % nominal 97 → 98.8%, precision % CV ≤ 2% in all quality control levels. The rabbit model's pharmacokinetic parameters were examined, and alectinib's area under the curve (AUC 0—∞) was 4269 ± 8.13 hr.ng/ml. The half-life of elimination (t1/2) is 8.52 ± 6.66 hours. The currently established approach was used in rabbit blood samples for pharmacokinetic investigations of commercial formulations since it was thought to be a novel, verified bioanalytical method based on experimental results

Experimental assessment of arsenic toxicity in garole sheep in India

Arsenic, a dangerous bio-accumulative poison, is a grave threat affecting a large number of people as well as animals throughout the World, particularly in Bangladesh and West Bengal, India. It is also a matter of concern as continuously entering into food chain through biotic and abiotic products. The present study was conducted to evaluate the experimental effect of arsenic toxicosis on Garole sheep of West Bengal. One group was subjected to oral arsenic exposure @ 6.6 mg Kg−1 over 133 days when rests considered as negative control. Periodical arsenic estimation in wool, urine and feces along with hemato-biochemical alteration were checked thoroughly. It was evident from the study that long term arsenic exposure exerted a significant (p < 0.01) alteration compared to normal animal which were further supported by clinical abnormalities. Exposed animals showed histological changes throughout major internal organs like coagulative necrosis of liver, tubular nephritis of kidney and acanthosis of skin etc. The bio-accumulative and excretion pattern of arsenic inside body were also well understood by the arsenic estimation study of wool, urine and feces which may be helpful for discussion regarding arsenic entry into food chain via animals

Dynamics of Hot QCD Matter -- Current Status and Developments

The discovery and characterization of hot and dense QCD matter, known as Quark Gluon Plasma (QGP), remains the most international collaborative effort and synergy between theorists and experimentalists in modern nuclear physics to date. The experimentalists around the world not only collect an unprecedented amount of data in heavy-ion collisions, at Relativistic Heavy Ion Collider (RHIC), at Brookhaven National Laboratory (BNL) in New York, USA, and the Large Hadron Collider (LHC), at CERN in Geneva, Switzerland but also analyze these data to unravel the mystery of this new phase of matter that filled a few microseconds old universe, just after the Big Bang. In the meantime, advancements in theoretical works and computing capability extend our wisdom about the hot-dense QCD matter and its dynamics through mathematical equations. The exchange of ideas between experimentalists and theoreticians is crucial for the progress of our knowledge. The motivation of this first conference named "HOT QCD Matter 2022" is to bring the community together to have a discourse on this topic. In this article, there are 36 sections discussing various topics in the field of relativistic heavy-ion collisions and related phenomena that cover a snapshot of the current experimental observations and theoretical progress. This article begins with the theoretical overview of relativistic spin-hydrodynamics in the presence of the external magnetic field, followed by the Lattice QCD results on heavy quarks in QGP, and finally, it ends with an overview of experiment results.Comment: Compilation of the contributions (148 pages) as presented in the `Hot QCD Matter 2022 conference', held from May 12 to 14, 2022, jointly organized by IIT Goa & Goa University, Goa, Indi

Identification of Groundwater Potential Zones Using Remote Sensing and GIS Techniques: A Case Study of the Shatt Al-Arab Basin

Rapid population growth has raised the groundwater resources demand for socio-economic development in the Shatt Al-Arab basin. The sustainable management of groundwater resources requires precise quantitative evaluation, which can be achieved by applying scientific principles and modern techniques. An integrated concept has been used in the current study to identify the groundwater potential zones (GWPZs) in the Shatt Al-Arab basin using remote sensing (RS), geographic information system (GIS), and analytic hierarchy process (AHP). For this purpose, nine groundwater occurrence and movement controlling parameters (i.e., lithology, rainfall, geomorphology, slope, drainage density, soil, land use/land cover, distance to river, and lineament density) were prepared and transformed into raster data using ArcGIS software. These nine parameters (thematic layers) were allocated weights proportional to their importance. Furthermore, the hierarchical ranking was conducted using a pairwise comparison matrix of the AHP in order to estimate the final normalized weights of these layers. We used the overlay weighted sum technique to integrate the layers for the creation of the GWPZs map of the study area. The map has been categorized into five zones (viz., very good, good, moderate, poor, and very poor) representing 4, 51, 35, 9, and 1% of the study area, respectively. Finally, for assessing the effectiveness of the model, the GWPZs map was validated using depth to groundwater data for 99 wells distributed over the basin. The validation results confirm that the applied approach provides significantly solid results that can help in perspective planning and sustainable utilization of the groundwater resources in this water-stressed region