Body-Snatching: Medicine and the Cartesian Threat

Twentieth century physicians are proud to be biological scientists. It is this feature above all others that distinguishes us from our predecessors. Because it is the badge of our progress in medicine, biology is often considered the essential core of medical care. Indeed, we can become so focused upon the biology inmedicine that all other aspects of caring for patients fade into a murky background of ill-defined sentimentality

On the existence of infinitely many closed geodesics on orbifolds of revolution

Using the theory of geodesics on surfaces of revolution, we introduce the period function. We use this as our main tool in showing that any two-dimensional orbifold of revolution homeomorphic to S^2 must contain an infinite number of geometrically distinct closed geodesics. Since any such orbifold of revolution can be regarded as a topological two-sphere with metric singularities, we will have extended Bangert's theorem on the existence of infinitely many closed geodesics on any smooth Riemannian two-sphere. In addition, we give an example of a two-sphere cone-manifold of revolution which possesses a single closed geodesic, thus showing that Bangert's result does not hold in the wider class of closed surfaces with cone manifold structures.Comment: 21 pages, 4 figures; for a PDF version see http://www.calpoly.edu/~jborzell/Publications/publications.htm

Predicted and observed evolution in the mean properties of Type Ia supernovae with redshift

Recent studies indicate that Type Ia supernovae (SNe Ia) consist of two groups - a "prompt" component whose rates are proportional to the host galaxy star formation rate, whose members have broader lightcurves and are intrinsically more luminous, and a "delayed" component whose members take several Gyr to explode, have narrower lightcurves, and are intrinsically fainter. As cosmic star formation density increases with redshift, the prompt component should begin to dominate. We use a two-component model to predict that the average lightcurve width should increase by 6% from z=0-1.5. Using data from various searches we find an 8.1% +/- 2.7% increase in average lightcurve width for non-subluminous SNe Ia from z=0.03 - 1.12, corresponding to an increase in the average intrinsic luminosity of 12%. To test whether there is any bias after supernovae are corrected for lightcurve shape we use published data to mimic the effect of population evolution and find no significant difference in the measured dark energy equation of state parameter, w. However, future measurements of time-variable w will require standardization of SN Ia magnitudes to 2% up to z=1.7, and it is not yet possible to assess whether lightcurve shape correction works at this level of precision. Another concern at z=1.5 is the expected order of magnitude increase in the number of SNe Ia that cannot be calibrated by current methods.Comment: 5 pages, 3 figures, accepted to ApJ Letters, addressed referee's comments, table adde

Thirty Years Of Wetland Conservation In Montana

In 1985 the Montana Legislature authorized the Department of Fish, Wildlife and Parks (FWP) to use funds from migratory bird hunting licenses “…for the protection, conservation, and development of wetlands in Montana”, thereby creating the Migratory Bird Wetland Program (a.k.a. State Duck Stamp Program).  Wetlands and their associated uplands provide critical nesting, foraging, brood-rearing, and migration habitat for waterfowl and other wetland-associated wildlife.  Wetlands also provide critical ecosystem functions important for our communities and wildlife, including water purification, flood control, and groundwater recharge.  FWP’s Migratory Bird Wetland Program is dedicated to conserving wetlands and associated uplands to benefit Montana’s wildlife, especially migratory birds, to enhance consumptive and non-consumptive recreational opportunities, and to maintain wetland systems for Montana’s citizens.  Since many of the opportunities were on private land, it was essential for FWP personnel to learn how best to work with farmers and ranchers to benefit their operations as well as wildlife and wetland values.  In addition to the partnership of private landowners, many other agencies and organizations have been partners in habitat projects.  The program has adapted to changing opportunities and conservation needs over time.  We will chronicle the past 30 years of program implementation, showcase successes, and discuss a philosophy for continued wetland conservation into the future

Depression predicts revascularization procedures for 5 years after coronary angiography.

OBJECTIVE:Depression has been reported to increase cardiac event rates and functional impairment in patients with coronary disease. This article describes the impact of depression on subsequent healthcare utilization for such patients. METHODS:One hundred ninety-eight health maintenance organization patients with stable coronary disease were interviewed after elective angiography using a structured psychiatric diagnostic scale. Cardiac events, hospitalizations, procedures, and costs were monitored for the next 5 years through automated data. Subjects were classified at the time of angiography by modified DSM-IV criteria into those with major, minor, and no depression. RESULTS:In univariate analyses, the no depression group (N = 136) was most likely to receive coronary artery bypass grafting (CABG) (61% vs. 36% in the major depression group vs. 27% in the minor depression group, p =.001), and the major depression group (N = 25) was most likely to receive percutaneous transluminal coronary angioplasty (PTCA) (44% vs. 14% in the minor depression group vs. 24% in the no depression group). The minor depression group (N = 37) was least likely to be hospitalized for cardiac reasons during follow-up (54% vs. 80% in the major depression group vs. 80% in the no depression group, p =.005). Five-year rates of myocardial infarction and death did not differ significantly between groups. Proportional hazard models showed that those in the depression groups differed in time from catheterization to CABG (chi2(2) = 11.9, p =.003) and time to PCTA (chi2(2) = 7.74, p =.02) after controlling for relevant covariates. Median regression showed that patients with no depression had higher costs during the first year but tended to have lower costs in years 2 through 5 than patients with minor or major depression. CONCLUSIONS:Depression status at angiography is associated with the need for revascularization and total healthcare costs for the following year

A detailed study of the diastereoselective catalytic hydrogenation of 6-hydroxytetrahydroisoquinoline-(3R)-carboxylic ester intermediates

A key step towards a highly-selective antagonist of ionotropic glutamate receptors entails the diastereoselective arene hydrogenation of an enantiopure tetrahydroisoquinoline. An extensive screen using parallel reactors was conducted and led to the discovery of several Pd/C catalysts giving high yield and improved diastereoselectivity from 75 : 25 to 95 : 5. A detailed kinetic study of the best system was performed and supports the reduction occuring in two-steps.

Late-Time Spectral Observations of the Strongly Interacting Type Ia Supernova PTF11kx

PTF11kx was a Type Ia supernova (SN Ia) that showed time-variable absorption features, including saturated Ca II H&K lines that weakened and eventually went into emission. The strength of the emission component of H{\alpha} increased, implying that the SN was undergoing significant interaction with its circumstellar medium (CSM). These features were blueshifted slightly and showed a P-Cygni profile, likely indicating that the CSM was directly related to, and probably previously ejected by, the progenitor system itself. These and other observations led Dilday et al. (2012) to conclude that PTF11kx came from a symbiotic nova progenitor like RS Oph. In this work we extend the spectral coverage of PTF11kx to 124-680 rest-frame days past maximum brightness. These spectra of PTF11kx are dominated by H{\alpha} emission (with widths of ~2000 km/s), strong Ca II emission features (~10,000 km/s wide), and a blue "quasi-continuum" due to many overlapping narrow lines of Fe II. Emission from oxygen, He I, and Balmer lines higher than H{\alpha} is weak or completely absent at all epochs, leading to large observed H{\alpha}/H{\beta} intensity ratios. The broader (~2000 km/s) H{\alpha} emission appears to increase in strength with time for ~1 yr, but it subsequently decreases significantly along with the Ca II emission. Our latest spectrum also indicates the possibility of newly formed dust in the system as evidenced by a slight decrease in the red wing of H{\alpha}. During the same epochs, multiple narrow emission features from the CSM temporally vary in strength. The weakening of the H{\alpha} and Ca II emission at late times is possible evidence that the SN ejecta have overtaken the majority of the CSM and agrees with models of other strongly interacting SNe Ia. The varying narrow emission features, on the other hand, may indicate that the CSM is clumpy or consists of multiple thin shells.Comment: 12 pages, 7 figures, 1 table, re-submitted to Ap