28,398 research outputs found

    Why HITnet kiosks didn\u27t hit the mark for sexual health education of Western Australian Aboriginal youth

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    Objective: To assess the use, appropriateness of, and staff feedback on specific sexual health modules, which were installed on Heuristic Interactive Technology (HITnet) kiosks at Aboriginal Community Controlled Health Services (ACCHS). The HITnet kiosks were aimed at Aboriginal youth visiting these sites. Methods: Modules on the HITnet kiosks were assessed for (1) cultural appropriateness using Yunkaporta’s Aboriginal pedagogy framework and (2) compliance with the World Health Organization’s (WHO) advice on key elements for comprehensive sexual health education for young people. Data measuring kiosk use were obtained through HITnet kiosk activity reports. An online survey of ACCHS staff was used to qualitatively assess use of, and staff perceptions of, HITnet kiosks. Results: Kiosk modules were consistent with seven of the eight elements of Yunkaporta’s framework and all of the WHO recommendations. The most popular module generated 3,066 purposeful sessions and the least popular module generated 724 purposeful sessions across nine sites in 2012. While teenagers were the most frequent of the kiosk user groups (39.5% in 2012), the majority of users (56%) were not in the target group (i.e. elders 4%, adults 25%, children 27%). Key issues reported by ACCHS staff (n=11) included: lack of clarity regarding staff responsibility for overseeing kiosk functionality; kiosks attracting “inappropriate ages”; and “lack of privacy” based on kiosk location, screen visibility, and absence of headphones preventing discreet access. Conclusions: The modules were tailored to a young Aboriginal audience through technology thought to be appealing to this group. However, barriers to use of the kiosk included kiosk design features, location, and lack of clarity around responsibility for kiosk operation. Implications: Aboriginal youth need easy access to sexual health messages in a ‘safe’, non-judgmental space. Information and communication that is accessible via personal and mobile devices may be a better vehicle than public kiosks

    Revised Bedrock Geology of War Eagle Quadrangle, Benton County, Arkansas

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    A digital geologic map of War Eagle quadrangle (WEQ) was produced at the 1:24000 scale using the geographic information system (GIS) software ArcView® by digitizing geological contacts onto the United States Geological Survey (USGS) digital raster graphic (DRG). The geology of WEQ consists of sedimentary rocks of Ordovician (Cotter, Powell, and Everton Formations), Devonian (Clifty Formation and Chattanooga Shale), and Mississippian (St. Joe-Boone, Batesville, and Fayetteville Formations) systems. Impoundment of Beaver Lake in 1966 inundated most Ordovician rocks cropping out in WEQ, but all three formations were present in isolated outcrops along the present shoreline of the lake. The St. Joe Limestone was mapped as a separate unit from the Boone Formation throughout WEQ and all four members of the St. Joe Limestone were observed, lending credence to suggestions that the St. Joe Limestone should be elevated to formation status. The Hindsville Member of the Batesville Formation and the Fayetteville Formation were mapped in an isolated outcrop along the extreme eastern boundary of WEQ. All formations within WEQ were highly fractured, and some prominent lineaments may represent faults with minor displacement. Several new normal faults were mapped in the central-eastern portion of the quadrangle, and the most prominent structural feature in the quadrangle was the northward extension of the Fayetteville Fault (also know as the Price Mountain Fault), which bisects the quadrangle from southwest to northeast

    Systematic assessment of HER2/neu in gynecologic neoplasms, an institutional experience.

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    BackgroundHER2/neu overexpression and/or amplification has been widely studied in a number of solid tumors, primarily in the breast. In gynecologic neoplasms, determination of HER2/neu status has not been well studied as a predictive biomarker in anti-HER2/neu treatment.MethodsWe systematically evaluated the HER2/neu reactions by immunohistochemistry and fluorescent in situ hybridization in malignant gynecologic neoplasms as experienced in our institution.ResultsThe HER2/neu overexpression or amplification occurred in 8 % of the cancers of the gynecological organs in our series. Majority of the HER2/neu overexpression and/or amplification occurred in clear cell (27 %) and serous (11 %) carcinomas. HER2/neu positivity was also seen in undifferentiated as well as in mixed clear cell and serous carcinomas. Discordant IHC and FISH results (positive by FISH but not IHC) was seen in 2 cases. Majority of the HER2/neu overexpression and/or amplification occurs in the endometrium rather than the ovary. Heterogeneity of the HER2/neu by IHC staining was in < 2 % of the tumors in our series.ConclusionsWe recommend the HER2/neu studies on Müllerian carcinomas of clear cell, serous, and undifferentiated types, particularly when they arise in the endometrium. Since there are some discordant IHC/FISH results, we also propose performing the HER2/neu testing by FISH when the IHC score is less than 3 + 

    Evaluation of positive G sub Z tolerance following simulated weightlessness (bedrest)

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    The magnitude of physiologic changes which are known to occur in human subjects exposed to varying levels of + G sub Z acceleration following bed rest simulation of weightlessness was studied. Bed rest effects were documented by fluid and electrolyte balance studies, maximal exercise capability, 70 deg passive tilt and lower body negative pressure tests and the ability to endure randomly prescribed acceleration profiles of +2G sub Z, +3G sub Z, and +4G sub Z. Six healthy male volunteers were studied during two weeks of bed rest after adequate control observations, followed by two weeks of recovery, followed by a second two-week period of bed rest at which time an Air Force cutaway anti-G suit was used to determine its effectiveness as a countermeasure for observed cardiovascular changes during acceleration. Results showed uniform and significant changes in all measured parameters as a consequence of bed rest including a reduced ability to tolerate +G sub Z acceleration. The use of anti-G suits significantly improved subject tolerance to all G exposures and returned measured parameters such as heart rate and blood pressure towards or to pre-bed-rest (control) values in four of the six cases
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