UV Upturn in Elliptical Galaxies: Theory

The UV upturn is the rising flux with decreasing wavelength between the Lyman limit and 2500\AA found virtually in all bright spheroidal galaxies. It has been a mystery ever since it was first detected by the OAO-2 space telescope (Code & Welch 1979) because such old metal-rich populations were not expected to contain any substantial number of hot stars. It was confirmed by following space missions, ANS (de Boer 1982), IUE (Bertola et al. 1982) and HUT (Brown et al. 1997). The positive correlation between the UV-to-optical colour (i.e., the strength of the UV upturn) and the Mg2 line strength found by Burstein et al. (1987) through IUE observations has urged theorists to construct novel scenarios in which metal-rich ($\gtrsim Z_{\odot}$) old ($\gtrsim$ a few Gyr) stars become UV bright (Greggio & Renzini 1990; Horch et al. 1992). Also interesting was to find using HUT that, regardless of the UV strength, the UV spectral slopes at 1000--2000\AA in the six UV bright galaxies were nearly identical suggesting a very small range of temperatures of the UV sources in these galaxies (Brown et al. 1997), which corresponds to $T_{\rm eff} \approx 20,000 \pm 3,000$ K. This, together with other evidence, effectively ruled out young stars as the main driver of the UV upturn. A good review on the observational side of the story is given in the next article by Tom Brown, as well as in the recent articles of Greggio & Renzini (1999) and O'Connell (1999).Comment: 6 figures; belated paper from Keele Conferenc

Lymphoscintigraphy and triangulated body marking for morbidity reduction during sentinel node biopsy in breast cancer

Current trends in patient care include the desire for minimizing invasiveness of procedures and interventions. This aim is reflected in the increasing utilization of sentinel lymph node biopsy, which results in a lower level of morbidity in breast cancer staging, in comparison to extensive conventional axillary dissection. Optimized lymphoscintigraphy with triangulated body marking is a clinical option that can further reduce morbidity, more than when a hand held gamma probe alone is utilized. Unfortunately it is often either overlooked or not fully understood, and thus not utilized. This results in the unnecessary loss of an opportunity to further reduce morbidity. Optimized lymphoscintigraphy and triangulated body marking provides a detailed 3 dimensional map of the number and location of the sentinel nodes, available before the first incision is made. The number, location, relevance based on time/sequence of appearance of the nodes, all can influence 1) where the incision is made, 2) how extensive the dissection is, and 3) how many nodes are removed. In addition, complex patterns can arise from injections. These include prominent lymphatic channels, pseudo-sentinel nodes, echelon and reverse echelon nodes and even contamination, which are much more difficult to access with the probe only. With the detailed information provided by optimized lymphoscintigraphy and triangulated body marking, the surgeon can approach the axilla in a more enlightened fashion, in contrast to when the less informed probe only method is used. This allows for better planning, resulting in the best cosmetic effect and less trauma to the tissues, further reducing morbidity while maintaining adequate sampling of the sentinel node(s)

Two Circular-Rotational Eigenmodes in Vortex Gyrotropic Motions in Soft Magnetic Nanodots

We found, by micromagnetic numerical and analytical calculations, that the clockwise (CW) and counterclockwise (CCW) circular-rotational motions of a magnetic vortex core in a soft magnetic circular nanodot are the elementary eigenmodes existing in the gyrotropic motion with respect to the corresponding CW and CCW circular-rotational-field eigenbasis. Any steady-state vortex gyrotropic motions driven by a linearly polarized oscillating in-plane magnetic field in the linear regime can be perfectly understood according to the superposition of the two circular eigenmodes, which show asymmetric resonance characteristics reflecting the vortex polarization. The relative magnitudes in the amplitude and phase between the CCW and CW eigenmodes determine the elongation and orientation of the orbital trajectories of the vortex core motions, respectively, which trajectories vary with the polarization and chirality of the given vortex as well as the field frequency across the resonance frequency.Comment: 30 pages, 7 figure

Neuroprotection and acidosis induced by cortical spreading depression

We read with interest the article “Cortical spreading depression produces a neuroprotective effect activating mitochondrial uncoupling protein-5” published in Neuropsychiatr Dis Treat by Viggiano et al.1 The authors showed that cerebral spreading depression (CSD) triggered uncoupling protein-5 (UCP-5),1 which had been reported to exert a long-term effect upon neuron protection.2 The result is another piece in CSD literature on modifying gene expressions to provide neuroprotection to subsequent ischemic episodes.3,

Midazolam Efficacy Against Acute Hydrogen Sulfide-Induced Mortality and Neurotoxicity.

Hydrogen sulfide (H2S) is a colorless, highly neurotoxic gas. It is not only an occupational and environmental hazard but also of concern to the Department of Homeland Security for potential nefarious use. Acute high-dose H2S exposure causes death, while survivors may develop neurological sequelae. Currently, there is no suitable antidote for treatment of acute H2S-induced neurotoxicity. Midazolam (MDZ), an anti-convulsant drug recommended for treatment of nerve agent intoxications, could also be of value in treating acute H2S intoxication. In this study, we tested the hypothesis that MDZ is effective in preventing/treating acute H2S-induced neurotoxicity. This proof-of-concept study had two objectives: to determine whether MDZ prevents/reduces H2S-induced mortality and to test whether MDZ prevents H2S-induced neurological sequelae. MDZ (4 mg/kg) was administered IM in mice, 5 min pre-exposure to a high concentration of H2S at 1000 ppm or 12 min post-exposure to 1000 ppm H2S followed by 30 min of continuous exposure. A separate experiment tested whether MDZ pre-treatment prevented neurological sequelae. Endpoints monitored included assessment of clinical signs, mortality, behavioral changes, and brain histopathological changes. MDZ significantly reduced H2S-induced lethality, seizures, knockdown, and behavioral deficits (p < 0.01). MDZ also significantly prevented H2S-induced neurological sequelae, including weight loss, behavior deficits, neuroinflammation, and histopathologic lesions (p < 0.01). Overall, our findings show that MDZ is a promising drug for reducing H2S-induced acute mortality, neurotoxicity, and neurological sequelae

THE ISSUE OF SITE AUTONOMY IN DISTRIBUTED DATABASE ADMINISTRATION

With the increasing trend towards distributed systems, the administration of distributed databases has become very important. A key issue in this environment is the degree of autonomy for each participating site. This paper classifies the degree of site autonomy into three different levels and provides some guidelines for determining the appropriate degree of site autonomy from both organizational and technological perspectives. The alternative organizational structure for database administration and the specific tasks assigned to a Global DBA and Local DBAs under different site autonomy policies is discussed. Finally, the three site autonomy policies are compared

Default Spread dan Term Spread sebagai Variabel Proxy Siklus Bisnis pada Model Fama-French

This research aims to apply the Fama-French models and test the effect of alternative variable of bond yield spread, default spread (RBBB – RAAA and RAAA – RF), and the term spread (RSUN10-RSUN1), as proxy variables of the business cycle, in IDX stock data during 2005-2010. Four types of asset pricing models tested are Sharpe-Lintner CAPM, Fama-French models, Hwang et al.model, and hybrid model. The results showed that the size effect and value effect has an impact on excess stock returns. Slopes of market beta, SMB, and HML are more sensitive to stock big size and high B / M. Default spreads and term spreads in Hwang et al. model can explain the value effect, and weakly explain the size effect, meanwhile the power of explanation disappeared on Hybrid models. Based on the assessment adjusted R2 and the frequency of rejection of non-zero alpha, is found that the hybrid model is the most suitable model

Nonvolatile memories using deep traps formed in HfO₂ by Nb ion implantation

We report nonvolatile memories (NVMs) based on deep-energy trap levels formed in HfO₂ by metal ion implantation. A comparison of Nb- and Ta-implanted samples shows that suitable charge-trapping centers are formed in Nb-implanted samples, but not in Ta-implanted samples. This is consistent with density-functional theory calculations which predict that only Nb will form deep-energy levels in the bandgap of HfO₂. Photocurrent spectroscopy exhibits characteristics consistent with one of the trap levels predicted in these calculations. Nb-implanted samples showing memory windows in capacitance–voltage (V) curves always exhibit current (I) peaks in I–V curves, indicating that NVM effects result from deep traps in HfO₂. In contrast, Ta-implanted samples show dielectric breakdowns during the I–V sweeps between 5 and 11 V, consistent with the fact that no trap levels are present. For a sample implanted with a fluence of 10¹³Nb cm⁻², the charge losses after 10⁴ s are ∼9.8 and ∼25.5% at room temperature (RT) and 85°C, respectively, and the expected charge loss after 10 years is ∼34% at RT, very promising for commercial NVMs