Maternal and Perinatal Outcome in Heart Disease Complicating Pregnancy One Year study in a Tertiary Care Centre

INTRODUCTION: Heart diseases complicating pregnancy constitute a major cause of non obstetric maternal deaths. This prospective study was conducted in a tertiary care centre over a period of one year. AIMS AND OBJECTIVES: To find the prevalence of heart diseases in women admitted for delivery or MTP in our institution and to know about the various heart diseases prevalent in them. MATERIALS AND METHODS: The study included 172 pregnant women with heart diseases of whom 15 underwent MTP. They were observed for maternal, cardiac and perinatal outcomes. RESULTS: The prevalence of heart disease was 1.08% in our study. RHD was the commonest type of heart disease. CONCLUSION: Heart disease constitute for a significant of number of maternal deaths. This can be prevented by a comprehensive multi disciplinary care

Comfort properties of double face knitted fabrics for tennis sportswear

The comfort properties of different bi-layer knitted structures made from tencel yarn as an outer layer and acrylic/micro-fibre polyester yarn as an inner layer have been studied. Six union fabrics have been produced and then analyzed objectively and subjectively for their comfort properties. The air permeability, water vapour permeability, wicking ability and drying rate are found to be higher and thermal resistance is found to be lower for bi-layer knitted fabric made out of micro-fibre polyester (inner layer) with less tuck points as compared to all other fabrics. The same structure shows good ranking on subjective rating of thermal environment scale. The results are discussed with 95% significant level with ANOVA analysis and Friedman one-way analysis of variance

Enlightening Network Lifetime based on Dynamic Time Orient Energy Optimization in Wireless Sensor Network

Mobile Ad-hoc Networks (MANET) are a set of Large-scale infrastructure and mobile device networks that build themselves without centralized control to provide various services through mobile. However, the quality of service of MANET is highly dependent on multiple parameters. Many routing schemes in literature use hop count, mobility speed, direction, etc. Similarly, the flow-based approach chooses long routes, which increases latency and reduces throughput efficiency. However, not all methods work well with all Quality of Service (QoS) parameters. To introduce a Dynamic Time Orient Energy Optimization (DTOEO) algorithm to construct the energy-based tree formation to achieve the minimum energy consumption network. Energy-based Dynamic Tree Routing to provide higher energy node and shortest route estimation that help to better transmission quality. In this proposed DTOEO method, perform three stages, there are i). Source node discovery process, ii). Time-orient density estimation, and iii). Energy-based Dynamic Tree Routing. In this stage, orient density estimation evaluates the data transmission size for each window period. To assess the consuming energy in the overall network. The proposed method of performance evaluation using various QoS matrices and its comparison to the existing process provides better performance

Influence of tuck stitch in wale direction on thermal comfort characteristics of layered knitted fabrics

Thermo-physiological comfort of the clothing has been studied considering the ability to manage heat and to transfersensible and insensible perspiration to the environment. Four bi-layer knitted fabrics are developed by changing the tuckstitch placement in four different points on wale, such as tuck on 4th, 8th, 12th and 16th wale with same course. It isobserved that the bi-layer knitted fabric with tuck on 12th wale exhibits better air, heat and moisture transfer as comparedto those with tuck on 4th, 8th, and 16th wales. The lower thickness and low mass per unit area exhibit better thermalconductivity, air permeability, water vapour permeability, wicking, moisture absorbency, drying rate and moisturemanagement properties. The less number of tuck stitch shows better thermal comfort characteristics considering bothobjective and wear trial method. The results are discussed with 95% significant level with ANOVA analysis andFriedman one-way analysis of variance

Influence of tuck stitch in course direction on thermal comfort characteristics of layered knitted fabrics

The thermal comfort characteristics of bi-layer knitted fabrics have been studied for shuttle badminton sportswear. Bilayerknitted fabrics are developed by changing tuck position in course direction such as 6, 10, 14 and 18 course repeat,keeping the tuck on 12th wale the same. It is observed that the greater the distance between successive tuck points, the betterwill be the air, heat and moisture transfer properties. Bi-layer knitted fabric with slack structure facilitates lower thicknessand mass per unit area, and exhibits better thermal comfort characteristics. By wear trial method, bi-layer knitted fabric withtuck on 18th course and 12th wale shows good rating compared to other bi-layer knitted fabrics. The results are discussed at95% significant level with ANOVA analysis and Friedman one-way analysis of variance

Value of Ki - 67 and p63 in Grading of Urothelial Neoplasms: An Immunohistochemical study

BACKGROUND: Bladder cancer is the ninth most common cancer in India and four times common in males than females. Over all incidences was 3.67 in males and 0.83 in females for 100,000 population. More than 90% of the bladder cancer are epithelial in origin and mostly are urothelial in type. Superficial and muscle-invasive urothelial carcinomas are two distinct types of the tumour having different biological behaviour and prognosis. More than 15% of superficial urothelial carcinoma progress to high-grade non invasive and subsequently invasive urothelial carcinoma. Detection of high-grade urothelial carcinoma is important for selection of therapy. Grading of urothelial carcinoma has prognostic significance. There is high inter observer variability in grading of urothelial neoplasms, even among the experienced pathologists. If the biopsies do not include the muscle tissue, the invasiveness of the tumour could not be assessed histopathologically. In such cases, markers which confirm the higher grade of the tumour and potential invasiveness, may be a surrogate indicator of the risk of recurrence and progression and may help in individualized therapy. Increased cellular proliferation correlates with biological aggressiveness of bladder tumours. Significant variation between Ki67 value and morphological grade of the tumour has been reported, so it might be helpful to do these marker studies to outline the individual therapy and prognosis. Expression of p63 by tumour cells indicates limited potential to progress to invasive disease and provides excellent prognosis. Impaired p63 expression characterizes the biological aggressiveness of urothelial neoplasms. MATERIALS AND METHODS: All tissue blocks of urothelial carcinoma are included in the study. Ki -67 and p63 immunohistochemistry performed in 50 cases of urothelial carcinoma. Expression of Ki -67 and p63 IHC in tumor cells are evaluated and compared with histological grade and clinical parameters. RESULTS: Decreased expression of Ki-67 was observed 80% in low grade urothelial carcinoma (16/20) whereas increased expression of Ki-67 was seen 90% in high grade urothelial carcinoma (27/30). Decreased expression of p63 was seen 95.5% (21/22) in high grade urothelial carcinoma and increased expression of p63 was seen in 64.3% (18/28) in low grade urothelial carcinoma. This result was statistically significant (p value < 0.05). CONCLUSION: The study data suggest that increased expression of Ki-67 and decreased expression of p63 is prevalent among high grade urothelial carcinoma and decreased expression of Ki-67 and increased expression of p63 is prevalent among low grade urothelial carcinoma. The increased proliferation of Ki-67 and decreased expression of p63 in low grade urothelial carcinoma cases may suggest aggressive clinical course and these cases may have increased chance of tumour recurrence and progression, so need further appropriate adjuvant treatment. Clinical trials are needed to determine the prognostic implications of these expressions

Clinical study on demographic profile, maternal and perinatal outcome in pregnant women with hypertensive disorders

BACKGROUND: Hypertensive disorders of pregnancy are the most common causes of adverse maternal and perinatal outcomes. Preeclampsia and eclampsia have been recognized as clinical entities since the times of Hippocrates. This study aims to determine the maternal and perinatal outcome in pregnant women with hypertensive disorders. AIMOF THE STUDY: To study the maternal and perinatal outcome in pregnant women with hypertensive disorders in Chengalpattu Medical College, Chengalpattu. METHOD: A descriptive study design was conducted at Chengalpattu Medical College from October 2016-September 2017 for a period of one year. 450 patients were studied and divided according to severity. RESULTS: Of the 450 women study ,the most common hypertensive type was severe preeclampsia with an incidence of 39.6% while the next common was mild preeclampsia with an incidence of 27.8% followed by Eclampsia of incidence 14.2%. Maternal complications occurred in 21.6% of cases most common was that of placental abruption [11.3] followed by PPH [6%] followed by HELLP [1.8%] followed by maternal mortality of 0.6%.Most common fetal complications was prematurity[30.9%] followed by IUGR [16%]. CONCLUSION: The clinical course of hypertensive disorders is progressive and is characterized by continuous deterioration that is ultimately stopped only by delivery. Early detection and appropriate management of Hypertensive disorders in pregnancy may improve the outcome for both the mother and fetus

Some results on the distance r-b-coloring in graphs

Given a positive integer r, two vertices u, v ∈ V (G) are r- independent if d(u, v) > r. A partition of V (G) into r-independent sets is called a distance r-coloring. A study of distance r-coloring and distance r-b-coloring concepts are studied in this paper.Publisher's Versio

Molecular identification of scale insect (Eulecanium giganteum) in Hibiscus rosa-sinensis

Hibiscus rosa-sinensis is a widely grown evergreen valuable medicinal, ornamental species planted in India. Scale insects are small herbivorous insects found on all continents and they are serious sap sucking pests of many ornamental plants. These scale insects are undetectable due to their tiny size, basic morphology, and polyphagous feeding nature. Hence, the management of these tiny insects become a serious concern across the globe. To afford a prospective solution to the problem, an accurate, simple, and developmental-stage-independent identification method is required, hence this study attempted the molecular identification of scale insect in Hibiscus rosa-sinensis using mitochondrial gene Cytochrome Oxidase Subunit I (mtCOI) sequencing. The experiment was carried out by isolating insect DNA using a modified CTAB method. Through two or three rounds of error-prone PCR followed by a steady procedure to amplify a mtCOI region. This region of mtCOI has been used as a standard DNA barcode for a diverse array of taxa. The confirmation has been done by sequencing of mtCOI which suggest the highest similarities with Eulecanium giganteum. This study addresses the questions of biodiversity and molecular characterization of scale insects. Further, the information obtained in this study provides baseline data for future crop improvement programs and integrated pest management strategies

Correlation of micronutrient status with atherogenic index and oxidative stress markers in metabolic syndrome

The prognostication of cardiovascular events in people with metabolic syndrome (MetS) is paramount due to their heightened risk profile. MetS is typified by a cluster of medical conditions such as raised blood pressure, hyperglycemia, central adiposity, and anomalous levels of cholesterol or triglycerides, which collectively increase the likelihood of developing cardiovascular disease. Anticipating cardiovascular events in these individuals enables enhanced prevention approaches, more efficient management, and better patient results. The present investigation involved an examination of the correlation between a range of biomarkers, namely Lp-PLA2, Apo A1, Apo B, hs-CRP, OxLDL, MDA, and Vitamin C, and the atherogenic index in a population afflicted with MetS. The results indicated no statistically significant association between the markers mentioned above and the atherogenic index within the sample population. This suggests that these markers may not possess sufficient predictive value for cardiovascular events in this demographic. Nevertheless, it was noted that although there was no discernible correlation with the atherogenic index, the MetS cohort exhibited increased serum concentrations of Lp-PLA2, OxLDL, and MDA. The markers mentioned above are widely recognized as reliable indicators of inflammation and oxidative stress, two crucial processes in the development of atherosclerosis and subsequent cardiovascular events. As a result, the increased prevalence of MetS may indicate heightened susceptibility to cardiovascular disease, underscoring the importance of implementing a comprehensive approach to managing cardiovascular risk in affected individuals. In summary, although the markers analyzed in this investigation may not directly associate with the atherogenic index, their increased concentrations warrant prudence and emphasize the significance of vigilant management of cardiovascular risk in individuals diagnosed with MetS. Accurately forecasting cardiovascular events remains a multifaceted obstacle that necessitates the examination of numerous variables and persistent scholarly endeavors