I Belong Here Too: An Oral History of the Immigration of Bangladeshis to New York City

I Belong Here Too is an oral history project which consists of twenty interviews of the Bangladeshi community in New York. The oral histories touch on many aspects of Bangladeshi-American life, history, memory, identity, culture, and the struggles of being an immigrant. It tries to put the interviewees experiences in a larger historical context in order to understand how the Bangladeshi community in Brooklyn, New York has grown and the challenges they faced as immigrants in a new city. The two chapters of this thesis examines the oral history processes and the difficulties of Bangladeshi immigrant women. The project is collaborating with the South Asian American Digital Archive (SAADA) where it hosts the stories of the interviewees. Link to the oral history project: https://www.saada.org/browse/collection/subat-matin-oral-history-interviews

I Belong Here Too: An Oral History of the Immigration of Bangladeshis to New York City

I Belong Here Too is an oral history project which consists of twenty interviews of the Bangladeshi community in New York. The oral histories touch on many aspects of Bangladeshi-American life, history, memory, identity, culture, and the struggles of being an immigrant. It tries to put the interviewees experiences in a larger historical context in order to understand how the Bangladeshi community in Brooklyn, New York has grown and the challenges they faced as immigrants in a new city. The two chapters of this thesis examines the oral history processes and the difficulties of Bangladeshi immigrant women. The project is collaborating with the South Asian American Digital Archive (SAADA) where it hosts the stories of the interviewees. Link to the oral history project: https://www.saada.org/browse/collection/subat-matin-oral-history-interviews

STUDI FENOLOGI PERKEMBANGAN BUNGA PADA MATOA KUNING (Pometia pinnata)

YOSI SUBAT AYU LESTARI (2023) : STUDI FENOLOGI PERKEMBANGAN BUNGA PADA MATOA KUNING (Pometia pinnata) Fenologi dan perkembangan bunga merupakan proses yang sangat penting dalam siklus hidup tumbuhan karena informasi ini dapat digunakan untuk menentukan sistem penyerbukan tanaman. Penelitian ini bertujuan untuk mengetahui fase-fase perkembangan fenologi dan tipe bunga pada matoa kuning. Penelitian ini telah dilaksanakan pada bulan Maret sampai Mei 2022 di kebun matoa Petani Desa Palas, Rumbai, Kota Pekanbaru. Pengamatan dilakukan terhadap 4 pohon matoa kuning yang telah berproduksi. Hasil penelitian menunjukan bahwa tahap perkembangan bunga dimulai dari inisiasi malai, trubus anak malai, kuncup besar, anthesis dan buah terbentuk, dan bunga matoa kuning memiliki 2 tipe, yaitu pseudo-hermaphrodite flowers dan functional hermaphrodite flowers dengan posisi malai Terminal dan bentuk malai Pyramidal. Warna kelopak bunga, stamen, kepala sari mengalami degradasi warna dari awal bunga muncul hingga bunga mekar (gradasi pucat menjadi lebih pekat). Lama waktu dalam siklus pembungaan dari inisiasi bunga hingga anthesis berkisar antara 57-68 hari, dengan jumlah rata-rata 12,91 malai pertandandan panjang malai 21,30 cm. Rata-rata jumlah bunga mencapai 4709,47 bunga pertandan dan fruitset 0,92% (46,25 buah pertandan). Kata kunci : anthesis, fruitset, functional hermaphrodite flower, pseudo hermaphrodit

Cardiomyocyte Contractile Dysfunction in the APPswe/PS1dE9 Mouse Model of Alzheimer's Disease

Ample clinical and experimental evidence indicated that patients with Alzheimer's disease display a high incidence of cardiovascular events. This study was designed to examine myocardial histology, cardiomyocyte shortening, intracellular Ca(2+) homeostasis and regulatory proteins, electrocardiogram, adrenergic response, endoplasmic reticulum (ER) stress and protein carbonyl formation in C57 wild-type (WT) mice and an APPswe/PS1dE9 transgenic (APP/PS1) model for Alzheimer's disease.Cardiomyocyte mechanical properties were evaluated including peak shortening (PS), time-to-PS (TPS), time-to-relengthening (TR), maximal velocity of shortening and relengthening (+/-dL/dt), intracellular Ca(2+) transient rise and decay.Little histological changes were observed in APP/PS1 myocardium. Cardiomyocytes from APP/PS1 but not APP or PS1 single mutation mice exhibited depressed PS, reduced+/-dL/dt, normal TPS and TR compared with WT mice(.) Rise in intracellular Ca(2+) was lower accompanied by unchanged resting/peak intracellular Ca(2+) levels and intracellular Ca(2+) decay in APP/PS1 mice. Cardiomyocytes from APP/PS1 mice exhibited a steeper decline in PS at high frequencies. The responsiveness to adrenergic agonists was dampened although beta(1)-adrenergic receptor expression was unchanged in APP/PS1 hearts. Expression of the Ca(2+) regulatory protein phospholamban and protein carbonyl formation were downregulated and elevated, respectively, associated with unchanged SERCA2a, Na(+)-Ca(2+) exchanger and ER stress markers in APP/PS1 hearts. Our further study revealed that antioxidant N-acetylcysteine attenuated the contractile dysfunction in APP/PS1 mice.Our results depicted overt cardiomyocyte mechanical dysfunction in the APP/PS1 Alzheimer's disease model, possibly due to oxidative stress

The Renal Parenchyma Evaluation: MAG3 vs. DMSA

Scintigraphy with Tc-99m dimercaptosuccinic acid (DMSA) is considered a reference method for assessment of parenchymal lesions and estimation of differential kidney function. The aim of study was to evaluate Tc-99m mercaptoacetyltriglycine (MAG3) dynamic renal scintigraphy for the same purpose. 188 patients, submitted to both studies within three months, were divided in two groups. In the first, 83 DMSA images were compared to parenchymal phase of MAG3 scintigraphy. Kidney morphology was independently evaluated by four observers. In the second group (N=105), differential function was calculated in MAG3 and DMSA studies and the respective results were compared. Findings corresponded completely in 85% of patients. There were no statistically significant differences between calculated differential function on DMSA and MAG3 images. The results showed that most of parenchymal lesions detected on DMSA scans can be identified on MAG3 parenchymal scans. Both studies can be equally used for the calculation of differential kidney function

The Renal Parenchyma Evaluation: MAG3 vs. DMSA

Scintigraphy with Tc-99m dimercaptosuccinic acid (DMSA) is considered a reference method for assessment of parenchymal lesions and estimation of differential kidney function. The aim of study was to evaluate Tc-99m mercaptoacetyltriglycine (MAG3) dynamic renal scintigraphy for the same purpose. 188 patients, submitted to both studies within three months, were divided in two groups. In the first, 83 DMSA images were compared to parenchymal phase of MAG3 scintigraphy. Kidney morphology was independently evaluated by four observers. In the second group (N=105), differential function was calculated in MAG3 and DMSA studies and the respective results were compared. Findings corresponded completely in 85% of patients. There were no statistically significant differences between calculated differential function on DMSA and MAG3 images. The results showed that most of parenchymal lesions detected on DMSA scans can be identified on MAG3 parenchymal scans. Both studies can be equally used for the calculation of differential kidney function

The Renal Parenchyma Evaluation: MAG3 vs. DMSA

Scintigraphy with Tc-99m dimercaptosuccinic acid (DMSA) is considered a reference method for assessment of parenchymal lesions and estimation of differential kidney function. The aim of study was to evaluate Tc-99m mercaptoacetyltriglycine (MAG3) dynamic renal scintigraphy for the same purpose. 188 patients, submitted to both studies within three months, were divided in two groups. In the first, 83 DMSA images were compared to parenchymal phase of MAG3 scintigraphy. Kidney morphology was independently evaluated by four observers. In the second group (N=105), differential function was calculated in MAG3 and DMSA studies and the respective results were compared. Findings corresponded completely in 85% of patients. There were no statistically significant differences between calculated differential function on DMSA and MAG3 images. The results showed that most of parenchymal lesions detected on DMSA scans can be identified on MAG3 parenchymal scans. Both studies can be equally used for the calculation of differential kidney function

Low-Dose Cd Induces Hepatic Gene Hypermethylation, along with the Persistent Reduction of Cell Death and Increase of Cell Proliferation in Rats and Mice

Cadmium (Cd) is classified as a human carcinogen probably associated with epigenetic changes. DNA methylation is one of epigenetic mechanisms by which cells control gene expression. Therefore, the present study genome-widely screened the methylation-altered genes in the liver of rats previously exposed to low-dose Cd.Rats were exposed to Cd at 20 nmol/kg every other day for 4 weeks and gene methylation was analyzed at the 48(th) week with methylated DNA immunoprecipitation-CpG island microarray. Among the 1629 altered genes, there were 675 genes whose promoter CpG islands (CGIs) were hypermethylated, 899 genes whose promoter CGIs were hypomethylated, and 55 genes whose promoter CGIs were mixed with hyper- and hypo-methylation. Caspase-8 gene promoter CGIs and TNF gene promoter CGIs were hypermethylated and hypomethylated, respectively, along with a low apoptosis rate in Cd-treated rat livers. To link the aberrant methylation of caspase-8 and TNF genes to the low apoptosis induced by low-dose Cd, mice were given chronic exposure to low-dose Cd with and without methylation inhibitor (5-aza-2'-deoxyctidene, 5-aza). At the 48(th) week after Cd exposure, livers from Cd-treated mice displayed the increased caspase-8 CGI methylation and decreased caspase-8 protein expression, along with significant increases in cell proliferation and overexpression of TGF-β1 and cytokeratin 8/18 (the latter is a new marker of mouse liver preneoplastic lesions), all which were prevented by 5-aza treatment.These results suggest that Cd-induced global gene hypermethylation, most likely caspase-8 gene promoter hypermethylation that down-regulated its expression, leading to the decreased hepatic apoptosis and increased preneoplastic lesions