7 research outputs found
Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain : Large-Scale Epidemiological Study
- Author
- Abdel Bouhmidi
- Alberto Mir
- Alejandro Hernández Camba
- Alfredo Abraldes Bechiarelli
- Alfredo J. Lucendo
- Amalia Carmona
- Amparo Sapiña
- Ana Echarri
- Ana Garre
- Ana Gutiérrez
- Ana María Fuentes Coronel
- Ana Monrobel
- Andrea Núñez Ortiz
- Beatriz Sicilia
- Belén Botella
- Belén Crespo Suarez
- Belén Herreros Martínez
- Carlos Castaño-Milla
- Cesar Ledezma
- Concepción Piñero
- Cristina Martínez Pascual
- Cristina Rodríguez
- Daniel Ginard
- Daniel Hervías
- Eduardo Iyo
- Elena Castro
- Elena Guerra del Río
- Emilio Torrella Cortés
- Estela Fernández Salgado
- Esther García-Esquinas
- Eugenia Sánchez Rodríguez
- Eva María Zapata
- Eva Sesé Abizanda
- Fernando Bermejo
- Fernando Gomollón
- Fernando Rodríguez-Artalejo
- Francisco J. Martínez-Cerezo
- Hipólito Fernández Rosáenz
- Horacio Alonso-Galán
- Ignacio Marín-Jiménez
- Inmaculada Alonso-Abreu
- Isabel Blázquez Gómez
- Isabel Nicolás
- Isabel Vera-Mendoza
- Javier P. Gisbert
- Jesús Barrio
- Jone Ortiz de Zarate
- Jordi Gordillo
- José Antonio Gómez-Valero
- José Joaquín Ramírez Palanca
- José Luis Cabriada
- José Luis F. Forcelledo
- José Manuel Benítez
- José María Duque
- José María Huguet
- José Miguel Marrero
- Juan Nerín de la Puerta
- Katerina Spicakova
- Laia Lluis
- Laura Mata
- Lidia Martí Romero
- Liliana Pozzati
- Lilyan Kolle
- Luis Fernández-Salazar
- Luis Hernández
- Manuel Barreiro-de Acosta
- Manuela Josefa Sampedro
- Marcos Kutz
- Margalida Calafat
- Margarita Menacho
- Margarita Muñoz Vicente
- Mariam Aguas
- Marta Soler
- María Chaparro
- María Dolores Martín-Arranz
- María Esteve Comas
- María José Alcalá
- María José Casanova
- María Luisa Galve
- María Montealegre
- María Tejada
- María Teresa Diz-Lois Palomares
- María Teresa Novella Durán
- Mercè Navarro-Llavat
- Milagros Vela
- Miriam Sabat
- Montserrat Rivero
- Mónica Sierra
- Noelia Cruz
- Nuria Jiménez
- Nuria Maroto
- on behalf of the EpidemIBD study group of GETECCU
- Orencio Bosch
- Pablo Navarro
- Pablo Vega
- Pilar López Serrano
- Pilar Robledo
- Pilar Varela Trastoy
- Raquel Camargo
- Raquel Vicente
- Rebeca Irisarri
- Rocío Ferreiro-Iglesias
- Rufo Lorente Poyatos
- Sabino Riestra
- Sandra Torra Alsina
- Silvia Rodríguez Mondéjar
- Verónica Opio
- Vicent Hernández
- Xavier Calvet
- Yolanda Ber
- Yolanda Torres Domínguez
- Álvaro Hernández-Martínez
- Ángel Ponferrada Díaz
- Óscar Roncero
- Publication venue
- 'MDPI AG'
- Publication date
- 01/01/2021
- Field of study
(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery
Correction : Chaparro et al. Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study. J. Clin. Med. 2021, 10, 2885
- Author
- Abraldes Bechiarelli Alfredo
- Aguas Mariam
- Alonso-Abreu Inmaculada
- Alonso-Galán Horacio
- Barreiro de-Acosta Manuel
- Barrio Jesús
- Benítez José Manuel
- Ber Yolanda
- Bermejo Fernando
- Blázquez Gómez Isabel
- Bosch Orencio
- Botella Belén
- Bouhmidi Abdel
- Cabriada José Luis
- Calafat Margalida
- Calvet Calvo Xavier
- Camargo Raquel
- Carmona Amalia
- Casanova María José
- Castaño-Milla Carlos
- Castro Elena
- Chaparro María
- Crespo Suarez Belén
- Cruz Noelia
- Diz-Lois Palomares María Teresa
- Duque José María
- Echarri Ana
- Esteve Comas María
- Fernández Rosáenz Hipólito
- Fernández Salgado Estela
- Fernández-Salazar Luis
- Ferreiro-Iglesias Rocío
- Forcelledo José Luis F.
- Fuentes Coronel Ana María
- Galve María Luisa
- García-Esquinas Esther
- Garre Ana
- Ginard Daniel
- Gomollón Fernando
- Gordillo Jordi
- Guerra del Río Elena
- Gutiérrez Ana
- Gómez-Valero José Antonio
- Hernández Camba Alejandro
- Hernández Luis
- Hernández Vicent
- Hernández-Martínez Álvaro
- Herreros Martínez Belén
- Hervías Daniel
- Huguet José María
- Irisarri Rebeca
- Iyo Eduardo
- Jiménez Nuria
- Josefa Sampedro Manuela
- José Alcalá María
- Kolle Lilyan
- Kutz Marcos
- Ledezma Cesar
- Lluis Laia
- Lorente Poyatos Rufo
- Lucendo Alfredo J.
- López Serrano Pilar
- Maroto Nuria
- Marrero José Miguel
- Martí Romero Lidia
- Martín-Arranz María Dolores
- Martínez Pascual Cristina
- Martínez-Cerezo Francisco J.
- Marín-Jiménez Ignacio
- Mata Laura
- Menacho Margarita
- Mir Alberto
- Monrobel Ana
- Montealegre María
- Muñoz Vicente Margarita
- Navarro Pablo
- Navarro-Llavat Mercè
- Nerín de la Puerta Juan
- Nicolás Isabel
- Novella Durán María Teresa
- Núñez Ortiz Andrea
- Opio Verónica
- Ortiz de Zarate Jone
- P. Gisbert Javier
- Piñero Concepción
- Ponferrada Díaz Ángel
- Pozzati Liliana
- Ramírez Palanca José Joaquín
- Riestra Sabino
- Rivero Montserrat
- Robledo Pilar
- Rodríguez Mondéjar Silvia
- Rodríguez Cristina
- Rodríguez-Artalejo Fernando
- Roncero Óscar
- Sabat Miriam
- Sapiña Amparo
- Sesé Abizanda Eva
- Sicilia Beatriz
- Sierra Ausín Mónica
- Soler Marta
- Spicakova Katerina
- Sánchez Rodríguez Eugenia
- Tejada María
- Torra Alsina Sandra
- Torrella Cortés Emilio
- Torres Domínguez Yolanda
- Universitat Autònoma de Barcelona
- Varela Trastoy Pilar
- Vega Pablo
- Vela Milagros
- Vera-Mendoza Isabel
- Vicente Raquel
- Zapata Eva María
- Publication venue
- 'MDPI AG'
- Publication date
- 01/01/2022
- Field of study
The authors wish to make the following corrections to this paper [...]
Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients
- Author
- Albersen Arjan
- Alemany Andrea
- Alonso Eva
- Amado Simon Rosa
- Ancochea Àgueda
- Ara Jordi
- Arcos Vila Gemma
- Band Caterina
- Baro Bàrbara
- Bassat Orellana Quique
- Benavent Sergio
- Berg – Rahman Juliette van der
- Bianco Andrea Sofia
- Blanco Guillermo Ignacio
- Blanco Ignacio
- Blanco Julian
- Bogers Susanne
- Bonet Papell Glòria
- Bonet Mireia
- Boomgaard Maartje van den
- Bordoy Antoni E.
- Bravo Anna
- Briones Zambrano Ney Nicanor
- Buitenhuis Lonneke
- Cantoni Jordi
- Capdevila Jáuregui Mar
- Carceles Peiró Victor
- Carrasco Matos Katherine M.
- Casamitjana Natàlia
- Casares Gonzalez Pablo
- Casañ Lopez Cristina
- Clotet i Sala Bonaventura
- Comas Leon Xavier
- Comellas Fernandez Laura
- Contreras Enric
- COnV-ert Study Group
- Corbacho Monné Marc
- Costes Gèlia
- CoV-Early Study Group
- Curriu Sabatès Margarida
- Dastis Arias Macarena
- Delgado Capel Maria
- Droog José de
- Díez Sánchez Beatriz
- Elst Kim van
- Engen Rene van
- Etten Ronald van
- Fernández Rivas Gema
- Ferrer Magí
- Ferrer Susana
- Flores Aguilera Begoña
- Forcada Anna
- Fornos Miriam
- Gallardo Mireia
- Galvan Femenia Ivan
- Gammeren Adriaan van
- Garcia Nadia
- García García Vanesa
- García Yolanda
- Geloven Nan van
- Geurtsvankessel Corine
- Gharbharan Arvind
- Giménez Montserrat
- Ginneken Betty van
- Gonzalez Ruiz Cristian
- González Beiras Camila
- González García David
- González Soler Victoria
- González María Isabel
- Groeneveld Geert
- Grífols Joan Ramon
- Gudiol Carlota
- Götz Hannelore
- Harvala Heli
- Hernández Luis
- Hernández Águeda
- Hiddema Siepke
- Hogema Boris
- Hollander Jan den
- Jiménez Zahida
- Jordans Carlijn
- Kampschreur Linda
- Karim Faiz
- Karisli Ayten
- Katsikis Peter
- Koopmans Marion
- Koster David
- Lammers Jolanda
- Leeuwen-Segarceanu Elena van
- Llopis Roca Ferran
- Lukens Michaèl
- Línio Rosa
- Maas Nanda
- Maglio Laura Analía
- Malchair Pierre
- Marfil Silvia
- Marks Michael
- Martinez Núria
- Meier Romy
- Miedema Jelle
- Millan Anna
- Millat Martínez Pere
- Mitjà Oriol
- Molenkamp Karin
- Mooijaart Simon
- Müller Yvonne
- Navarrete Gonzalez Laura
- Nieto Rodríguez Raquel
- Nieto Aroa
- Otero Aurema
- Ouchi Dan
- Oud Josine
- Papageourgiou Grigorios
- París Alexa
- Piccolo Ferreira Francini
- Pons Barber Maria
- Postma Douwe
- Pradenas Edwars
- Prat Núria
- Puig Jordi
- Ramírez Morros Anna
- Ramírez Viaplana Ferran
- Reimerink Johan
- Reitsma Annette
- Reusken Chantal
- Rijnders Bart J. A.
- Roca Font Judit
- Rodriguez Arias Miquel Angel
- Rodriguez Cortez Orlando
- Rodríguez Codina Joana
- Rodríguez Sevilla Graciela
- Rokx Casper
- Rokx Casper
- Rokx-Niemantsverdriet Lotte
- Roquer López Clàudia
- Ruibal Suarez Jose Carlos
- Ruiz Comellas Anna
- Russcher Henk
- San José Alba
- Saüch Valmaña Glòria
- Scherpenisse Cees
- Scholtens Thea
- Schoot Ellen van der
- Soetekouw Robert
- Struik Jelle
- Suñer Navarro Clara
- Swaneveld Francis
- Tarres García Silvia
- Torrano Soler Pamela
- Trinité Benjamin
- Troxel Andrea
- Ubals Maria
- Vall Mayans Martí
- Verdaguer Joaquim
- Verstijnen Jose
- Vidal Alaball Josep
- Vidal Obradors Carla
- Videla Sebas
- Viozquez Meya Maria
- Vivero Larraza Ainhoa
- Vonderen Marit van
- Vrielink Hans
- Vértiz Guidotti Thatiana
- Watering Leo van de
- Wijngaarden Peter van
- Zarauza Pellejero Alvaro
- Zwaginga Jaap Jan
- Zwaginga Lisa
- Zwet Erik van
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 23/06/2022
- Field of study
Data on convalescent plasma (CP) treatment in COVID-19 outpatients are scarce. We aimed to assess whether CP administered during the first week of symptoms reduced the disease progression or risk of hospitalization of outpatients. Two multicenter, double-blind randomized trials (NCT04621123, NCT04589949) were merged with data pooling starting when = 50 years and symptomatic for <= 7days were included. The intervention consisted of 200-300mL of CP with a predefined minimum level of antibodies. Primary endpoints were a 5-point disease severity scale and a composite of hospitalization or death by 28 days. Amongst the 797 patients included, 390 received CP and 392 placebo; they had a median age of 58 years, 1 comorbidity, 5 days symptoms and 93% had negative IgG antibody-test. Seventy-four patients were hospitalized, 6 required mechanical ventilation and 3 died. The odds ratio (OR) of CP for improved disease severity scale was 0.936 (credible interval (CI) 0.667-1.311); OR for hospitalization or death was 0.919 (CI 0.592-1.416). CP effect on hospital admission or death was largest in patients with <= 5 days of symptoms (OR 0.658, 95%CI 0.394-1.085). CP did not decrease the time to full symptom resolution
Peri-operative red blood cell transfusion in neonates and infants: NEonate and Children audiT of Anaesthesia pRactice IN Europe: A prospective European multicentre observational study
- Author
- Adelais Tsiotou
- Adriana Gurita
- Afroditi Karafotia
- Albert Castellheim
- Alberto Izquierdo
- Alena Zlámalová
- Alessandra Moscarelli
- Alessandra Verzelloni
- Alessandro Vittori
- Alessia Montaguti
- Aliaksandra Parashchanka
- Alice Miskovic
- Alicia Chamizo
- Alicja Bartkowska-Sniatkowska
- Alison Hare
- Ana Mandras
- Ana Markić
- Ana Peleteiro
- Anda Zundane
- Anders Bastholm Bille
- Andrea Cortegiani
- Andrea Wolfler
- Andreas Machotta
- Andreas Weyland
- Andrew Blevin
- Andrew Robertson
- András Petróczy
- Angela Pistorio
- Anita Reil
- Anja Diers
- Ann Kvarnström
- Anna Camporesi
- Anna Guddo
- Anna Malisiova
- Anna-Ursina Malär
- Anne Laffargue
- Anne Lesage
- Anne M Beukers
- Annemie Bauters
- Anouk Van der Knijff-van Dortmont
- Anthony R Absalom
- Antonella Cotoia
- Arash Afshari
- Armin Flinspach
- Arta Barzdina
- Artemis Polyzoi
- Artur Baranowski
- Aslı Sagun
- Aurélien Legrand
- Aurélien Zang
- Ayse Çiğdem Tutuncu
- Balázs Hauser
- Barbe Pieters
- Barbora Cabanová
- Bas Van Zaane
- Beate Kuppers
- Benjamin Urbina
- Bernard Coustets
- Bernd Schmitz
- Bernhard Koller
- Biljana Drašković
- Brendan O'Hare
- Brigitte Messerer
- Brita De Lorenzo
- Bruno Guido Locatelli
- Camilla Micalizzi
- Carine Marcucci
- Carmel Cassar
- Carmelo Minardi
- Carmen Scott
- Carol Bodlani
- Carolin Aehling
- Carolina Tormo de Las Heras
- Caroline Couchepin
- Caroline Lejus-Bourdeau
- Caroline Pregardien
- Catarina Cruz Esteves
- Catherine Amory
- Catherine Baujard
- Ceferina Suárez Castaño
- Celia Allison
- Celia Arbona
- Cesare Vezzoli
- Chiara Grasso
- Chris Perry
- Christa Boer
- Christiane Goeters
- Christoph Eisner
- Christoph Menzel
- Christophe Dadure
- Chrystelle Sola
- Chulananda Goonasekera
- Claudia Hoehne
- Claudia Neumann
- Clelia Zanaboni
- Clemens Schorer
- Cristina Agapiti
- Cristina Auli
- Cristina González Serrano
- Cécile Magne
- Dan Gilpin
- Daniel Richter
- Daniela Lerro
- Daniela Pupacic
- Daphne Michelet
- Dario Galante
- Darja Janjatovic
- David Alders
- David Artés
- David Barnes
- David Kahn
- David Pachter
- de Graaff J. C.
- Despoina Iordanidou
- Diana Butković
- Dilek Özcengiz
- Dina Bert
- Dina Emal
- Disma N.
- Dmytro Dmytriiev
- Dolores Méndez
- Dorota Lewandowska
- Dusica Simic
- Edgar Székely
- Edoardo Calderini
- Eleana Garini
- Elena Attanasi
- Elena Gordeva
- Elena Lenares
- Elena Vilardell Ortíz
- Eliane Khalil
- Elisa Reponen
- Ellie Walker
- Elvan Öçmen
- Emanuele Rossetti
- Emese Nyíri
- Emilie Druot
- Emma Meehan
- Emma Pontén
- Erik Ramon Isern
- Ernesto Martínez García
- Erzsebet Sapi
- Esther Ngan
- Eva Schafrat
- Evangelia Bali
- Fabio Caramelli
- Fabio Sbaraglia
- Fanny Fabre
- Federico Bilotta
- Florence Julien-Marsollier
- France Stevens
- Francesca Pinzoni
- Francis Veyckemans
- Francisco Escribá
- Frank Wappler
- Franz-Josef Kretz
- François de la Brière
- François Semjen
- Fuchs A.
- Gabor Erdoes
- Gabriel Mocioiu
- Gail Scoones
- Gema Pino
- Gerald Rogan Neba
- Gergely Göbl
- Gert-Jan Scheffer
- Gilda Cinnella
- Gilles Orliaguet
- Girolamo Mattioli
- Giulia Bottazzi
- Giulia Frasacco
- Giuliana Anna Porro
- Giuseppe Staiti
- Graham Bell
- Gregor Badelt
- Gulsen Keskin
- Guner Kaya
- Gyula Tövisházi
- Habre W.
- Hale Aksu Erdost
- Handan Birbiçer
- Hannah King
- Hannu Kokki
- Heiko Kaiser
- Helena Salgado
- Hervé Dupont
- Hilmi Ayanoglu
- Hugues Ludot
- Ilona Razlevice
- Inge De Liefde
- Inger Marie Drage
- Irena Maraulaite
- Irena Simic
- Irena Vulicevic
- Irene García Martínez
- Irina Milojevic
- Irina Trante
- Isabel Eggemann
- Isabelle Constant
- Isabelle Pichon
- Isole Edelman
- Iulia Cindea
- Ivan Kohn
- Ivana Budic
- Ivana Kerovec Sorić
- Ivana Petrov
- Jacqueline Mauch
- James Armstrong
- Jan Schreiber
- Janos Schnur
- Jarkko Harju
- Jarl Reinhard
- Jean-Paul Mission
- Jelena Berger
- Jenni Vieri
- Jeremy Tomas
- Jesús Cebrián
- Jiří Žurek
- Joanne Norman
- Johan Berghmans
- Johanes Eger
- Johanna Ulrici
- John Emery
- Joke De Ruiter
- Jordanka Ilic
- Joris Vundelinckx
- Josip Azman
- Josko Markic
- Jost Kaufmann
- Jowita Rosada-Kurasińska
- Joy Abbott
- Judit Csillag
- Juliet Wolfe Barry
- Juliette Godart
- Jurgen Dertinger
- Jurgen Van Limmen
- Jutta Scheffczik
- János Gál
- Kai Zacharowski
- Kariantti Kallio
- Karin Becke
- Karin Hochmuth
- Karin Jonckheer
- Karin Oeinck
- Karin Oppenrieder
- Karina Jakubowska
- Karine Nouette Gaulain
- Kathryn James
- Katy Nicholson
- Kerstin Sandström
- Kevin Goddard
- Khairi Shah
- Koen Lapage
- Kristoffer Stensrud
- L Amaki Sogbodjor
- Laszlo Vutskits
- Laura Brigitta Colantonio
- Laura Lukosiene
- Laurent Hertz
- Leila Mameli
- Leila Messroghli
- Lena Brunner
- Lenka Knoppová
- Lesley McKee
- Li-En Tan
- Lilica Ros
- Lindsay Crate
- Lisa Daniels
- Lonneke Staals
- Loredana Oana
- Luc De Baerdemaeker
- Luc Tielens
- Lucia Scordo
- Lucie Sabau
- Luminita Ilie
- Lynn Uhrig
- Lynne Waring
- Léa Petry
- Magdalena Juzwa-Sobieraj
- Magdalena Mierzewska-Schmidt
- Magdalena Urban-Lechowicz
- Maja Suica
- Malgorzata Grzeskowiak
- Mandy Jackson
- Manuela Platzer
- Margot Bergsma
- Marguerite Ellekvist
- Mari-Liis Ilmoja
- Maria Cristina Mondardini
- Maria Domingas Patuleia
- Maria Garcia
- Maria João Santos
- Maria Sammartino
- Maria Soares
- Maria Vittinghof
- Mariangela Giombini
- Marianne Veldhuizen
- Marieke Voet-Lindner
- Marielle Buitenhuis
- Marija Stevic
- Marina Pandurov
- Marinella Astuto
- Mark Hendriks
- Mark Ross
- Mark Worrall
- Markus Stevens
- Markus Weigand
- Markus Wilbs
- Martin Hölzle
- Martin Jöhr
- Martin Söhle
- Martin Vavřina
- Martin Volkers
- Martina Stichlberger
- Maryline Bordes
- Marzena Zielinska
- María Isabel Villalobos Rico
- Mathias Marchon
- Matthias Klages
- Mattias Casutt
- Maurizia Grazzini
- Mehdi Bennis
- Melanie Schäfer
- Merja Kokki
- Merle Väli
- Michael Laschat
- Michael Schöler
- Michaela Löffler
- Michal Frelich
- Michelle Casey
- Michelle Quinney
- Micol Maffioletti
- Mihai Morariu
- Miia Kokkonen
- Miloslav Hanula
- Mine Akin
- Miriam Ochsenreiter
- Mirjana Knezevic
- Mirko Dolci
- Monica Gandhi
- Montserrat Suarez Comas
- Moreno Favarato
- Mustafa Azizoglu
- Myriam Bellon
- Nada Sabourdin
- Nadia Najafi
- Nadine Dobby
- Nalini Malarkkan
- Nandor Kosik
- Nargis Ahmad
- Natalia Sierra Biddle
- Natalie Cooper
- NECTARINE Group of the European Society of Anaesthesiology and Intensive Care Clinical Trial Network: Christian Breschan
- Nicola Zadra
- Nicolas Leister
- Nikola Stankovic
- Nil Ekiz
- Noemie Audren
- Nurcan Doruk
- Nuria Masip
- Nuria Montferrer Estruch
- Olivier Jacqmarcq
- Osvaldo Pérez Pardo
- Pablo De la Arena
- Pablo Troncoso Montero
- Paloma Rubio
- Panagoula Mammi
- Paul Martin
- Paul Smith
- Paul Stevens
- Pedro Pina
- Pelagia Chloropoulou
- Pelin Corman Dincer
- Pertti Suominen
- Peter Brooks
- Peter Frykholm
- Peter Kranke
- Petr Reimer
- Petra Cajková
- Petronella Mari Vermeulen
- Philippa Dix
- Philippe Pirat
- Philippe Roulleau
- Piet Wyffels
- Pilar Del Rey de Diego
- Pinar Kendigelen
- Pinelopi Papagiannopoulou
- Piotr Sawicki
- Pomianek Przemyslaw
- Prakash Krishnan
- Rachele Bonfiglio
- Radu Tabacaru
- Rainer Dörenberg
- Raisa Vähätalo
- Rebecca Pad
- Reet Kikas
- Reet Moor
- René Urbanec
- Richard Ellerkmann
- Rients De Boer
- Rita Scalisi
- Riva T.
- Rob Bomont
- Roberto Leone
- Robin Sunderland
- Rodica Badeti
- Rodrigo Poves-Álvarez
- Rose Fesseau
- Rossella Garra
- Rudolf Likar
- Ruth Cohausz
- Ruth Kroess
- Sadia Adil
- Sam De Silva
- Sami Suvanto
- Sandra Kralik
- Sandra Lako
- Sandra Numan
- Sara Mele
- Sarah Bell
- Sarah Gallagher
- Sascha Haussmann
- Sascha Meier
- Sebastian Richter
- Sebastian Weiterer
- Selena Puric Racic
- Sergio Picardo
- Shahab Ghamari
- Sibel Baris
- Silvia López
- Silvia Serrano
- Simona Anna Finamore
- Simone Lindau
- Simonetta Tesoro
- Sinead Harte
- Sirin Yücetepe
- Sladjana Vasiljevic
- Sophie Childs
- Souhayl Dahmani
- Sporre Bengt
- Sridevi Kuchi
- Stefan De Hert
- Stefan Heschl
- Stefan Seiler
- Stefano Scalia Catenacci
- Stephanie Bew
- Stephanie Jinks
- Stephanie King
- Stephanie Mifsud
- Stuart Blain
- Suellen Walker
- Susana Manrique Muñoz
- Susanna Keilig
- Svetlana Kotzeva
- Sílvia Pinho
- Teresa Leal
- Thierry Pirotte
- Thomas Bruelisauer
- Thomas Descarpentries
- Thomas Erb
- Thomas Fischer
- Thomas Hurni
- Thomas Mueller
- Tjerk Zweers
- Tom Hansen
- Tom Terboven
- Torsten Baehner
- Tumay Umuroglu
- Tuula Manner
- Ulf Lindestam
- Ulmer F.
- Uwe Trieschmann
- Vagia Ntritsou
- Valentin Munteanu
- Valter Sonzogni
- Veronika Maráczi
- Veronique Depret-Donatien
- Vesna Marjanovic
- Victoria Barlow
- Vimmi Oshan
- Virag K.
- Vladimír Mixa
- Wenche B Boerk
- Wolfgang Buhre
- Yann Bögli
- Yann Hamonic
- Yesim Senayli
- Yvona Sedláčková
- Yvonne Jelting
- Zane Straume
- Zdenka Rados
- Zeenat Nawoor
- Zehra Hatipoğlu
- Çimen Olguner
- Špela Pirtovšek Štupnik
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2022
- Field of study
BACKGROUND: Little is known about current clinical practice concerning peri-operative red blood cell transfusion in neonates and small infants. Guidelines suggest transfusions based on haemoglobin thresholds ranging from 8.5 to 12 g dl-1, distinguishing between children from birth to day 7 (week 1), from day 8 to day 14 (week 2) or from day 15 (≥week 3) onwards. OBJECTIVE: To observe peri-operative red blood cell transfusion practice according to guidelines in relation to patient outcome. DESIGN: A multicentre observational study. SETTING: The NEonate-Children sTudy of Anaesthesia pRactice IN Europe (NECTARINE) trial recruited patients up to 60 weeks' postmenstrual age undergoing anaesthesia for surgical or diagnostic procedures from 165 centres in 31 European countries between March 2016 and January 2017. PATIENTS: The data included 5609 patients undergoing 6542 procedures. Inclusion criteria was a peri-operative red blood cell transfusion. MAIN OUTCOME MEASURES: The primary endpoint was the haemoglobin level triggering a transfusion for neonates in week 1, week 2 and week 3. Secondary endpoints were transfusion volumes, 'delta haemoglobin' (preprocedure - transfusion-triggering) and 30-day and 90-day morbidity and mortality. RESULTS: Peri-operative red blood cell transfusions were recorded during 447 procedures (6.9%). The median haemoglobin levels triggering a transfusion were 9.6 [IQR 8.7 to 10.9] g dl-1 for neonates in week 1, 9.6 [7.7 to 10.4] g dl-1 in week 2 and 8.0 [7.3 to 9.0] g dl-1 in week 3. The median transfusion volume was 17.1 [11.1 to 26.4] ml kg-1 with a median delta haemoglobin of 1.8 [0.0 to 3.6] g dl-1. Thirty-day morbidity was 47.8% with an overall mortality of 11.3%. CONCLUSIONS: Results indicate lower transfusion-triggering haemoglobin thresholds in clinical practice than suggested by current guidelines. The high morbidity and mortality of this NECTARINE sub-cohort calls for investigative action and evidence-based guidelines addressing peri-operative red blood cell transfusions strategies. TRIAL REGISTRATION: ClinicalTrials.gov, identifier: NCT02350348
Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE): a prospective European multicentre observational study
- Author
- 6\ue7men Elvan
- 6zcengiz Dilek
- \u17durek Ji\u159\ued
- Abbott Joy
- Absalom Anthony R.
- Adil Sadia
- Aehling Carolin
- Afshari Arash
- Agapiti Cristina
- Ahmad Nargis
- Akin Mine
- Alders David
- Allison Celia
- Amory Catherine
- Arbona Celia
- Armstrong James
- Art\ue9s David
- Astuto Marinella
- Attanasi Elena
- Audren Noemie
- Auli Cristina
- Ayanoglu Hilmi
- Azizoglu Mustafa
- Azman Josip
- B\uf6gli Yann
- Badelt Gregor
- Badeti Rodica
- Baehner Torsten
- Bali Evangelia
- Baranowski Artur
- Baris Sibel
- Barlow Victoria
- Barnes David
- Bartkowska-Sniatkowska Alicja
- Barzdina Arta
- Baujard Catherine
- Bauters Annemie
- Becke Karin
- Bell Graham
- Bell Sarah
- Bellon Myriam
- Bengt Sporre
- Bennis Mehdi
- Beno\ueet Plichon
- Berger Jelena
- Berghmans Johan
- Bergsma Margot
- Bert Dina
- Beukers Anne M.
- Bew Stephanie
- Bille Anders Bastholm
- Bilotta Federico
- Birbi\ue7er Handan
- Blain Stuart
- Blevin Andrew
- Bodlani Carol
- Boer Christa
- Boerke Wenche B.
- Bomont Rob
- Bonfiglio Rachele
- Bordes Maryline
- Bottazzi Giulia
- Breschan Christian
- Brigitte Leva
- Brooks Peter
- Bruelisauer Thomas
- Brunner Lena
- Budic Ivana
- Buhre Wolfgang
- Buitenhuis Marielle
- Butkovi\u107 Diana
- Cabanov\ue1 Barbora
- Cajkov\ue1 Petra
- Calderini Edoardo
- Camporesi Anna
- Caramelli Fabio
- Casey Michelle
- Cassar Carmel
- Castellheim Albert
- Casutt Mattias
- Cebri\ue1n Jes\ufas
- Chamizo Alicia
- Childs Sophie
- Chloropoulou Pelagia
- Cindea Iulia
- Cinnella Gilda
- Cohausz Ruth
- Colantonio Laura Brigitta
- Constant Isabelle
- Cooper Natalie
- Cortegiani Andrea
- Cotoia Antonella
- Couchepin Caroline
- Coustets Bernard
- Crate Lindsay
- Csillag Judit
- D\uf6renberg Rainer
- Dadure Christophe
- Dahmani Souhayl
- Daniels Lisa
- De Baerdemaeker Luc
- De Boer Rients
- de Graaff Jurgen
- De Hert Stefan
- De la Arena Pablo
- de la Bri\ue8re Fran\ue7ois
- De Liefde Inge
- De Lorenzo Brita
- De Ruiter Joke
- De Silva Sam
- Del Rey de Diego Pilar
- Depret-Donatien Veronique
- Dertinger Jurgen
- Descarpentries Thomas
- Diers Anja
- Dincer Pelin Corman
- Disma Nicola
- Disma Nicola
- Dix Philippa
- Dmytriiev Dmytro
- Dobby Nadine
- Dolci Mirko
- Doruk Nurcan
- Dra\u161kovi\u107 Biljana
- Drage Inger Marie
- Druot Emilie
- Dupont Herv\ue9
- Edelman Isole
- Eger Johanes
- Eggemann Isabel
- Eisner Christoph
- Ekiz Nil
- Ellekvist Marguerite
- Ellerkmann Richard
- Emal Dina
- Emery John
- Engelhardt Thomas
- Erb Thomas
- Erdoes Gabor
- Erdost Hale Aksu
- Escrib\ue1 Francisco
- Esteves Catarina Cruz
- Fabre Fanny
- Favarato Moreno
- Fesseau Rose
- Finamore Simona Anna
- Fischer Thomas
- Flinspach Armin
- Frasacco Giulia
- Frelich Michal
- Frykholm Peter
- G\ue1l J\ue1nos
- G\uf6bl Gergely
- Galante Dario
- Gallagher Sarah
- Gandhi Monica
- Garc\ueda Mart\uednez Irene
- Garcia Maria
- Garini Eleana
- Garra Rossella
- Ghamari Shahab
- Gilpin Dan
- Giombini Mariangela
- Godart Juliette
- Goddard Kevin
- Goeters Christiane
- Gonz\ue1lez Serrano Cristina
- Goonasekera Chulananda
- Gordeva Elena
- Grasso Chiara
- Grazzini Maurizia
- Grzeskowiak Malgorzata
- Guddo Anna
- Gurita Adriana
- H\uf6lzle Martin
- Habre Walid
- Habre Walid
- Hamonic Yann
- Hansen Tom
- Hanula Miloslav
- Hare Alison
- Harju Jarkko
- Harte Sinead
- Hatipo\u11flu Zehra
- Hauser Bal\ue1zs
- Haussmann Sascha
- Hendriks Mark
- Hertz Laurent
- Heschl Stefan
- Hochmuth Karin
- Hoehne Claudia
- Hurni Thomas
- Ilic Jordanka
- Ilie Luminita
- Ilmoja Mari-Liis
- Iordanidou Despoina
- Isern Erik Ramon
- Izquierdo Alberto
- J\uf6hr Martin
- Jackson Mandy
- Jacqmarcq Olivier
- Jakubowska Karina
- James Kathryn
- Janjatovic Darja
- Jelting Yvonne
- Jinks Stephanie
- Jonckheer Karin
- Julia Dowell
- Julien-Marsollier Florence
- Juzwa-Sobieraj Magdalena
- Kahn David
- Kaiser Heiko
- Kallio Kariantti
- Karafotia Afroditi
- Katalin Vir\ue1g
- Kaufmann Jost
- Kaufmann Jost
- Kaya Guner
- Keilig Susanna
- Kendigelen Pinar
- Kerovec Sori\u107 Ivana
- Keskin Gulsen
- Khalil Eliane
- Kikas Reet
- King Hannah
- King Stephanie
- Klages Matthias
- Knezevic Mirjana
- Knoppov\ue1 Lenka
- Kohn Ivan
- Kokki Hannu
- Kokki Merja
- Kokkonen Miia
- Koller Bernhard
- Kosik Nandor
- Kotzeva Svetlana
- Kralik Sandra
- Kranke Peter
- Kretz Franz-Josef
- Krishnan Prakash
- Kroess Ruth
- Kuchi Sridevi
- Kuppers Beate
- Kvarnstr\uf6m Ann
- L\uf3pez Silvia
- L\uf6ffler Michaela
- Laffargue Anne
- Lako Sandra
- Lapage Koen
- Laschat Michael
- Lauweryns Julie
- Leal Teresa
- Legrand Aur\ue9lien
- Leister Nicolas
- Lejus-Bourdeau Caroline
- Lenares Elena
- Leone Roberto
- Lerro Daniela
- Lesage Anne
- Lewandowska Dorota
- Likar Rudolf
- Lindau Simone
- Lindestam Ulf
- Locatelli Bruno Guido
- Ludot Hugues
- Lukosiene Laura
- M\ue9ndez Dolores
- Machotta Andreas
- Maffioletti Micol
- Magne C\ue9cile
- Mal\ue4r Anna-Ursina
- Malarkkan Nalini
- Malisiova Anna
- Mameli Leila
- Mammi Panagoula
- Mandras Ana
- Manner Tuula
- Manrique Mu\uf1oz Susana
- Mar\ue1czi Veronika
- Maraulaite Irena
- Marchon Mathias
- Marcucci Carine
- Marjanovic Vesna
- Marki\u107 Ana
- Markic Josko
- Mart\uednez Garc\ueda Ernesto
- Martin Paul
- Masip Nuria
- Mattioli Girolamo
- Mauch Jacqueline
- McKee Lesley
- Meehan Emma
- Meier Sascha
- Mele Sara
- Menzel Christoph
- Messerer Brigitte
- Messroghli Leila
- Micalizzi Camilla
- Michelet Daphne
- Mierzewska-Schmidt Magdalena
- Mifsud Stephanie
- Milojevic Irina
- Minardi Carmelo
- Miskovic Alice
- Mission Jean-Paul
- Mixa Vladim\uedr
- Mocioiu Gabriel
- Mondardini Maria Cristina
- Montaguti Alessia
- Montferrer Estruch Nuria
- Moor Reet
- Morariu Mihai
- Moscarelli Alessandra
- Mueller Thomas
- Munteanu Valentin
- Najafi Nadia
- Nawoor Zeenat
- Neba Gerald Rogan
- Neumann Claudia
- Ngan Esther
- Nicholson Katy
- Norman Joanne
- Nouette Gaulain Karine
- Ntritsou Vagia
- Numan Sandra
- Ny\uedri Emese
- O\u2019Hare Brendan
- Oana Loredana
- Ochsenreiter Miriam
- Oeinck Karin
- Olguner \uc7imen
- Oppenrieder Karin
- Orliaguet Gilles
- Oshan Vimmi
- P\ue9rez Pardo Osvaldo
- Pachter David
- Pad Rebecca
- Pandurov Marina
- Papagiannopoulou Pinelopi
- Parashchanka Aliaksandra
- Patuleia Maria Domingas
- Peleteiro Ana
- Perry Chris
- Petr\uf3czy Andr\ue1s
- Petrov Ivana
- Petry L\ue9a
- Picardo Sergio
- Pichon Isabelle
- Pierre Harlet
- Pieters Barbe
- Pina Pedro
- Pinho S\uedlvia
- Pino Gema
- Pinzoni Francesca
- Pirat Philippe
- Pirotte Thierry
- Pirtov\u161ek \u160tupnik \u160pela
- Pistorio Angela
- Platzer Manuela
- Polyzoi Artemis
- Pont\ue9n Emma
- Porro Giuliana Anna
- Poves-\uc1lvarez Rodrigo
- Pregardien Caroline
- Prisca Feijten
- Przemyslaw Pomianek
- Pupacic Daniela
- Puric Racic Selena
- Quinney Michelle
- Rados Zdenka
- Razlevice Ilona
- Reil Anita
- Reimer Petr
- Reinhard Jarl
- Reponen Elisa
- Richter Daniel
- Richter Sebastian
- Riva Thomas
- Riva Thomas
- Robertson Andrew
- Ros Lilica
- Rosada-Kurasi\u144ska Jowita
- Ross Mark
- Rossetti Emanuele
- Roulleau Philippe
- Rubio Paloma
- S\uf6hle Martin
- Sabau Lucie
- Sabourdin Nada
- Sagun Asl\u131
- Salgado Helena
- Sammartino Maria
- Sandstr\uf6m Kerstin
- Santos Maria Jo\ue3o
- Sapi Erzsebet
- Sarah Herbineaux
- Sawicki Piotr
- Sbaraglia Fabio
- Scalia Catenacci Stefano
- Scalisi Rita
- Sch\ue4fer Melanie
- Sch\uf6ler Michael
- Schafrat Eva
- Scheffczik Jutta
- Scheffer Gert-Jan
- Schmitz Bernd
- Schnur Janos
- Schorer Clemens
- Schreiber Jan
- Scoones Gail
- Scordo Lucia
- Scott Carmen
- Sedl\ue1\u10dkov\ue1 Yvona
- Seiler Stefan
- Semjen Fran\ue7ois
- Senayli Yesim
- Serrano Silvia
- Shah Khairi
- Sierra Biddle Natalia
- Simic Dusica
- Simic Irena
- Smith Paul
- Soares Maria
- Sogbodjor L. Amaki
- Sola Chrystelle
- Sonzogni Valter
- Staals Lonneke
- Staiti Giuseppe
- Stankovic Nikola
- Stensrud Kristoffer
- Stevens France
- Stevens Markus
- Stevens Paul
- Stevic Marija
- Stichlberger Martina
- Straume Zane
- Su\ue1rez Casta\uf1o Ceferina
- Suarez Comas Montserrat
- Suica Maja
- Sunderland Robin
- Suominen Pertti
- Suvanto Sami
- Sz\ue9kely Edgar
- T\uf6vish\ue1zi Gyula
- Tabacaru Radu
- Tan Li-En
- Terboven Tom
- Tesoro Simonetta
- Tielens Luc
- Tomas Jeremy
- Tormo de las Heras Carolina
- Trante Irina
- Trieschmann Uwe
- Troncoso Montero Pablo
- Tsiotou Adelais
- Tutuncu Ayse \uc7i\u11fdem
- Uhrig Lynn
- Ulrici Johanna
- Umuroglu Tumay
- Urban-Lechowicz Magdalena
- Urbanec Ren\ue9
- Urbina Benjamin
- V\ue4h\ue4talo Raisa
- V\ue4li Merle
- Van der Knijff-van Dortmont Anouk
- Van Limmen Jurgen
- Van Zaane Bas
- Vasiljevic Sladjana
- Vav\u159ina Martin
- Veldhuizen Marianne
- Vermeulen Petronella Mari
- Verzelloni Alessandra
- Veyckemans Francis
- Vezzoli Cesare
- Vieri Jenni
- Vilardell Ort\uedz Elena
- Villalobos Rico Mar\ueda Isabel
- Virag Katalin
- Vittinghof Maria
- Vittori Alessandro
- Voet-Lindner Marieke
- Volkers Martin
- Vulicevic Irena
- Vundelinckx Joris
- Vutskits Laszlo
- Walker Ellie
- Walker Suellen
- Wappler Frank
- Waring Lynne
- Weigand Markus
- Weiterer Sebastian
- Weyland Andreas
- Wilbs Markus
- Wolfe Barry Juliet
- Wolfler Andrea
- Worrall Mark
- Wyffels Piet
- Y\ufccetepe Sirin
- Zacharowski Kai
- Zadra Nicola
- Zanaboni Clelia
- Zang Aur\ue9lien
- Zielinska Marzena
- Zl\ue1malov\ue1 (ne\ue9 Kv\u11bto\u148ov\ue1) Alena
- Zundane Anda
- Zweers Tjerk
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
International audienceBackground: Neonates and infants are susceptible to hypoxaemia in the perioperative period. The aim of this study was to analyse interventions related to anaesthesia tracheal intubations in this European cohort and identify their clinical consequences.Methods: We performed a secondary analysis of tracheal intubations of the European multicentre observational trial (NEonate and Children audiT of Anaesthesia pRactice IN Europe [NECTARINE]) in neonates and small infants with difficult tracheal intubation. The primary endpoint was the incidence of difficult intubation and the related complications. The secondary endpoints were the risk factors for severe hypoxaemia attributed to difficult airway management, and 30 and 90 day outcomes.Results: Tracheal intubation was planned in 4683 procedures. Difficult tracheal intubation, defined as two failed attempts of direct laryngoscopy, occurred in 266 children (271 procedures) with an incidence (95% confidence interval [CI]) of 5.8% (95% CI, 5.1-6.5). Bradycardia occurred in 8% of the cases with difficult intubation, whereas a significant decrease in oxygen saturation (SpO2<90% for 60 s) was reported in 40%. No associated risk factors could be identified among co-morbidities, surgical, or anaesthesia management. Using propensity scoring to adjust for confounders, difficult anaesthesia tracheal intubation did not lead to an increase in 30 and 90 day morbidity or mortality.Conclusions: The results of the present study demonstrate a high incidence of difficult tracheal intubation in children less than 60 weeks post-conceptual age commonly resulting in severe hypoxaemia. Reassuringly, the morbidity and mortality at 30 and 90 days was not increased by the occurrence of a difficult intubation event
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdag Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
- Almeida Braga Sara
- Almeida Filipe
- Almigheerbi Alabas
- Almoqayyad Abdelrahman
- Almuzghi Fakhruddin
- Alnoury Mostafa
- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
- Alsalameh Barah
- Alsallaq Osama
- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
- Alsharqawi Nourah
- Alswerki Mohammad
- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
- Alves do Canto Brum Homero
- Alves Daniela Macedo
- Alves Magda
- Alvi Abdul
- Alwaheidi Malak
- Alwali Abdallah
- Alwerfally AbdulMawlay
- Alwhaidi Noor
- Alyafi Amr
- Alzabti Fatima
- Alzahaf Ahmed
- AlZohour Mohammad
- Amadou Magagi Ibrahim
- Amandito Radhian
- Amarin Justin Z.
- Amaro Margarida
- Ambrazevicius Marijus
- Amendola Alfonso
- Amin Leila
- Amine Souadka
- Amjad Talal
- Amorim Edgar
- Amro Adham
- Anandan Premkumar
- Anas khalifa Rawda
- Anastasio Lorenzo
- Andersson Yvette
- Andreotti Dario
- Andrew David
- André Benoît
- Ang Sue Ean
- Angel Miguel
- Anggita Gultom Phebe
- Annapureddy Naga
- Anokhin Evgeny
- Ansaloni Luca
- Ansarei Dhirar
- Ansari Abdul Basit
- Antaky Marco
- Anthony Natasha
- Anthoulakis Christos
- Antonopoulou Maria Ioanna
- Anwar Mohamed
- Anwer Abdul Wahid
- Anyanwu Chikamuche
- Anyanwu Lofty-John
- Anyanwu Mercy Chinemerem
- Anyomih Theophilus Teddy Kojo
- Appukuttan Akhila
- Aquilino Fabrizio
- Archibald Jess
- Arciénega Yañez María del pilar
- Argentou Maria-Ioanna
- Argudo Nuria
- Argyriou Eleftherios Orestis
- Arias Madrid Natalia
- Aribi Sarra
- Arifin Ghafur Rasyid
- Arizpe Daniel
- Arnaud Alexis P
- Arora Bharti
- Arora Deeksha
- Arowolo Olukayode
- Arrangoiz Rodrigo
- Arslan Ekin
- Artigau Eva
- Ashfaq Ahsan
- Ashour Dina
- Ashour Firas
- Ashoushan Hana
- Ashraf Ahmed
- Ashraf Alaa
- Asif Ashar
- Asnel Dorisme
- Asok Anjitha
- Assa Rawan
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- Winter Des
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- Wondoh Paul M.
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- Wong Hsu Ven
- Wong Jane J
- Wong Jeremy
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- Yaghi Yasmine
- Yahia Mohamed Ali Mohamed
- Yakushkina Al'ona
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- Yang P Zichu
- Yanikoglu Erkan
- Yanni Fady
- Yates Charlotte
- Ye Geoffrey
- Yeen Chin Leow
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- Yenli Edwin
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- Zabiyaka Mikhail
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- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Šatkauskas Mindaugas
- Škimelyte Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 30/01/2021
- Field of study
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdağ Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
- Almeida Braga Sara
- Almeida Filipe
- Almigheerbi Alabas
- Almoqayyad Abdelrahman
- Almuzghi Fakhruddin
- Alnoury Mostafa
- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
- Alsalameh Barah
- Alsallaq Osama
- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
- Alsharqawi Nourah
- Alswerki Mohammad
- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
- Alves do Canto Brum Homero
- Alves Daniela Macedo
- Alves Magda
- Alvi Abdul
- Alwaheidi Malak
- Alwali Abdallah
- Alwerfally AbdulMawlay
- Alwhaidi Noor
- Alyafi Amr
- Alzabti Fatima
- Alzahaf Ahmed
- AlZohour Mohammad
- Amadou Magagi Ibrahim
- Amandito Radhian
- Amarin Justin Z.
- Amaro Margarida
- Ambrazevicius Marijus
- Amendola Alfonso
- Amin Leila
- Amine Souadka
- Amjad Talal
- Amorim Edgar
- Amro Adham
- Anandan Premkumar
- Anas khalifa Rawda
- Anastasio Lorenzo
- Andersson Yvette
- Andreotti Dario
- Andrew David
- André Benoît
- Ang Sue Ean
- Angel Miguel
- Anggita Gultom Phebe
- Annapureddy Naga
- Anokhin Evgeny
- Ansaloni Luca
- Ansarei Dhirar
- Ansari Abdul Basit
- Antaky Marco
- Anthony Natasha
- Anthoulakis Christos
- Antonopoulou Maria Ioanna
- Anwar Mohamed
- Anwer Abdul Wahid
- Anyanwu Chikamuche
- Anyanwu Lofty-John
- Anyanwu Mercy Chinemerem
- Anyomih Theophilus Teddy Kojo
- Appukuttan Akhila
- Aquilino Fabrizio
- Archibald Jess
- Arciénega Yañez María del pilar
- Argentou Maria-Ioanna
- Argudo Nuria
- Argyriou Eleftherios Orestis
- Arias Madrid Natalia
- Aribi Sarra
- Arifin Ghafur Rasyid
- Arizpe Daniel
- Arnaud Alexis P
- Arora Bharti
- Arora Deeksha
- Arowolo Olukayode
- Arrangoiz Rodrigo
- Arslan Ekin
- Artigau Eva
- Ashfaq Ahsan
- Ashour Dina
- Ashour Firas
- Ashoushan Hana
- Ashraf Ahmed
- Ashraf Alaa
- Asif Ashar
- Asnel Dorisme
- Asok Anjitha
- Assa Rawan
- Assalhi Mohamed
- Asta Martina
- Asti Emanuele Luigi Giuseppe
- Atakul Onur
- Atallah Khalid
- Atanasov Boyko
- Atawneh Mohammad
- Athamneh Sarah
- Ather Muaaz
- Athisayaraj Thomas
- Atkociunas Aivaras
- Attia Mohamed
- Au Angela
- Awad Israa
- Awadallah Haneen
- Awaji Kholoud
- Awesat Eman
- Awolowo Ajibola
- Ayandipo Omobolaji
- Ayash Mohammad
- Ayau Fernanda
- Ayesh Kholoud
- Ayman El-sawy Esraa
- Ayoub Rami
- Aytac Erman
- Ayub Bushra
- Ayub Saima
- Ayyad Rawan
- Azevedo José
- Azodo Ijeoma
- Azzubia Joma
- B L Ashika
- Ba Mouhamadou Bachir
- Babaa Basheer
- Babirye Lilian
- Bacic Ivan
- Badr Esraa Tarek
- Badr Helmy
- Badran Abdul
- Badwe Rajendra
- Bafford Andrea Chao M.D.
- Baggaley Caitlin
- Bahroun Sumayyah Ghayth
- Baiao José Miguel
- Baiocchi Daniella
- Bairos Menezes Maria
- Baiu Ioana
- Bajilan Mohammad
- Bajomo Oreoluwa
- Bake Jacques
- Baki Bahadir Emre
- Bakoleas Panagiotis
- Balaawi Reem
- Balalis Dimitrios
- Balata Mohamed
- Balkarov Artem
- Ballouhey Quentin
- Balogun Olanrewaju
- Baloyiannis Ioannis
- Baltaci Ege
- Bamaca Ixcajoc Elvis Benjamin
- Banaz Tuba
- Banda Bitiel
- Banglani Muntaha
- Bani Hani Farah
- Bani hani Mohammad
- Bani hani Zeina
- Baniowda Muath
- Banks Alexander
- Bannister Sharon
- Baranyai Zsolt
- Barati Nastaran
- Barbosa Camacho Francisco José
- Barbosa José
- Bardos David
- Barendegere Venerand
- Barghuthi Lutfi
- Barhoush Ola
- Barnes Nicole
- Baronio Gianluca
- Barreda Zelaya Lilian Elizabeth
- Barrera López Francisco Javier
- Barsic Neven
- Barter Charlotte
- Bartosiak Katarzyna
- Basarab Maksym
- Basso Stefano Maria Massimiliano.
- Bastiaenen Vivian
- Batashki Ilia
- Bath Michael
- Beattie Miriam
- Bedada Alemayehu Ginbo
- Belais Fanny
- Belal qadomi Asef
- Belev Nikolay
- Belli Andrea
- Beltrán de Heredia Juan
- Belvedere Angela
- Ben Dallah Najah
- Ben Saoud Abdulsalam Ali
- Bengur Fuat Baris
- Benkabbou Amine
- Benke Marton
- Benyaiche Chaymae
- Bergeat Damien
- Bernstein Mitchell
- Beshtawi Doha
- Besli Sevval
- Beuran Mircea
- Bhandare Manish
- Bhangu Aneel
- Bhatti Muhammad Iqbal
- Bianchini Stefania
- Bianco Francesco
- Bibas Fatma
- Biccard Bruce M
- Bielosludtsev Oleksii
- Bienfait Mumbere
- Billy Matthew
- Bin Mohamad Sithik Muhammad Navid
- Binetti Margherita
- Bingham Janne
- Bird Jonathan
- Birindelli Arianna
- Birks Sarah
- Birutis Justas
- Björklund Ida
- Blackman Brighid
- Blackwell James
- Blanco-Colino Ruth
- Blok Robin
- Blomme Nina
- Blomqvist Malin
- Blunnie Eimear
- Bnhameida Sondos
- Boddy Alex
- Bodur Muhammed Selim
- Boereboom Catherine
- Bogusevicius Algirdas
- Bolzonaro Elisa
- Bonavina Luigi
- Bondurri Andrea
- Bonghaseh Divine Tim
- Bono Lorenzo
- Borda-Luque Giuliano
- Borg Elaine
- Borghi Felice
- Borham Hala
- Borowski David W
- Bortolasi Luca
- Bosch Marina
- Bosire Fridah
- Bossi Daniela
- Botes Azel
- Bouaziz Hanen
- Bougard Heather
- Boutall Adam
- Boutros Marylise
- Bouzaiene Hatem
- Boyce Stephen
- Boyd-Carson Hannah
- Boyle Connor
- Braccio Bartolomeo
- Bradulskis Saulius
- Brata Santi Yuanita
- Bratu Matei Razvan
- Brito Diana
- Brocklehurst Peter
- Brooker Ethan
- Brooks Savannah
- Brown James
- Bruce Eilidh
- Bsisu Isam
- Bua Emmanuel
- Bucci Luigi
- Budd Gabrielle
- Budzyński Andrzej
- Budzyński Piotr
- Bujda Michele
- Bulaya Anadi
- Bullock Cameron
- Burger Sule
- Burgu Gökçen
- Burke Daniel
- Burman Shivang
- Bury Pawel
- Busuttil Zachary
- Butt Eman
- Buxant Frederic
- Buzaite Kristina
- C S Archana
- Caballero Díaz Yurena
- Cabrera Rivera Paulo Andrés
- Cagigas Fernandez Carmen
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- Tutino Roberta
- Tuynman Jurriaan
- Tyselskiy Volodimir
- Tzovaras George
- Tüfek Ozan yavuz
- Türkyilmaz Serdar
- Ubartas Nerijus
- Ubiali Paolo
- Ugoletti Lara
- Ugolini Giampaolo
- Uluşahin Mehmet
- Umenze Franklin
- Umoke Ifeanyi
- Underwood Charlotte
- Unger Lukas Walter
- Urbieta Aitor
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- Uribe Valencia Andres
- Usai Antonella
- Usta Arif
- Utrilla Fornals Alejandra
- Uwakunda Carine
- Uy Gemma Leonora
- Uysal Muhammed
- V Sushmita
- Valente da Costa Ana
- Valle Aranda Yener Cristyell
- van Berge Henegouwen Mark
- van Berge Henegouwen Mark I.
- van Dalen Anne Sophie
- Van Der Merwe Lisa Hannah
- van Geloven Aaw
- Van hentenryck Marie
- van Praag Elise Maria
- van Schilt Kaz
- Van Straten Stephanie
- van Wyngaard Tirsa
- Vanagas Tomas
- Vanella Serafino
- Vanoye Elva Gabriela
- Vardanyan Armen
- Varghese Shriya
- Varol Ecenur
- Vaska Ashish I
- Vaughan-Shaw Peter G
- Vaysse Charlotte
- Vazquez Fernandez Andrea
- Veale Kelly
- Vega Victor
- Veiga Diogo
- Velez Cristina
- Vella Ivan
- Venskutonis Donatas
- Venturelli Paolina
- Venturini Sara
- Verdaguer Tremolosa Mireia
- Vergara María
- Vergara-Fernandez Omar
- Verjee Azmina
- Vervoort Dominique
- Vescio Giuseppina
- Viacheslav Nezamai
- Vicario Bravo Marina
- Vidal Meza Maitza Rosario
- Vieira Barros Aldo
- Vieira Caroço Teresa
- Vieira Ana
- Vieira Bárbara
- Vigorita Vincenzo
- Vijeyan Harinthiran
- Viljoen Francois
- Villalobos Santiago
- Vincenti Leonardo
- Violi Paola
- Virbickaite Egle
- Vlek Stijn
- Volovetskyi Anton
- Wafaa Mariam
- Wafqui fatima Zahraa
- Wagner Gabriela
- Wakkaf Habib
- Wall Ellen
- Walsh Una
- Walter Catherine
- Walędziak Maciej
- Wan Khazim Wan Khamizar
- Wan Muhmad Wan Farahiyah
- Wandschneider Wiebke
- Wanniang Cliff
- Waqar Shahzad Hussain
- Warden Claire
- Warren Craig Russell
- Warren Oliver
- Warwick Andrea
- Warwicker Sean
- Wason Deepender
- Waterman Ade
- Watts Daniel
- Weiser Thomas G
- Welch Matthew
- Wellington Jack
- Wells Anna
- Wells Cameron
- West Malcolm
- Westerduin Emma
- Weyl Ariane
- Whisker Lisa
- Whitaker John
- White Rebecca
- Wiberg Rebecca
- Widmer Lukas Werner
- Wierdak Mateusz
- Wijekoon Arachchilage Nimeshi
- Wilguens Lartigue Jean
- Willemin Melissa
- Williams Christopher Yee Khang
- Wills Vanessa
- Wilson Karim
- Wilson Michael
- Wimmer Kerstin
- Windsor John
- Wineberg Devorah
- Winiarski Marek
- Winoto Hadi
- Winter Beatty Jasmine
- Winter Des
- Wisal Maham
- Wisselink Daan
- Wogensen Fredrik
- Wondoh Paul M.
- Wong Florence
- Wong Hsu Ven
- Wong Jane J
- Wong Jeremy
- Wong Lai Fen
- Wong Michael Pak-Kai
- Wong Sui-Weng
- Wong Tsz Lun Ernest
- Wood Lauren
- Woon-Shoo-Tong Xiao-Ming Sarah
- Wren Sherry
- Wuraola Funmilola
- Xanthopoulou Georgia
- Yabut Kenneth
- Yacoub Aseel
- Yaghi Nadine
- Yaghi Yasmine
- Yahia Mohamed Ali Mohamed
- Yakushkina Al'ona
- Yalçinkaya Ali
- Yang P Zichu
- Yanikoğlu Erkan
- Yanni Fady
- Yates Charlotte
- Ye Geoffrey
- Yeen Chin Leow
- Yemez Kürşat
- Yenidünya Nilüfer
- Yenli Edwin
- Yeo Jeremy
- Yeoh Andrea
- Yepez Raul
- Yeşilsancak Merve
- Yildirim Reyyan
- Yildiz Alp
- Yilmaz Duygu
- Yip Ching Wan
- Ylatoma Díaz Edgar Alcides
- Yong Shun Qi
- Yoong Andrel
- Yorke Joseph
- Yotsov Tsanko
- You Lucia
- Younes Eman
- Younes Maha
- Yousry Basant
- Yozgatli Tahir Koray
- Yu Kristin
- Yue Sum Yu Pansy
- Yunes Asmaa
- Yusuf Baasil
- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Čepuliené Daiva
- Şahin Can
- Šatkauskas Mindaugas
- Škimelytè Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/2022
- Field of study
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research