CCS and NH_3 Emission Associated with Low-Mass Young Stellar Objects

In this work we present a sensitive and systematic single-dish survey of CCS emission (complemented with ammonia observations) at 1 cm, toward a sample of low- and intermediate-mass young star-forming regions known to harbor water maser emission, made with NASA's 70 m antenna at Robledo de Chavela, Spain. Out of the 40 star-forming regions surveyed in the CCS (2_(1)-1_(0)) line, only six low-mass sources show CCS emission: one transitional object between the prestellar and protostellar Class 0 phase (GF9-2), three Class 0 protostars (L1448-IRS3, L1448C, and B1-IRS), a Class I source (L1251A), and a young T Tauri star (NGC 2071 North). Since CCS is considered an "early-time" (≲10^5 yr) molecule, we explain these results by either proposing a revision of the classification of the age of NGC 2071 North and L1251A, or suggesting the possibility that the particular physical conditions and processes of each source affect the destruction/production of the CCS. No statistically significant relationship was found between the presence of CCS and parameters of the molecular outflows and their driving sources. Nevertheless, we found a significant relationship between the detectability of CCS and the ammonia peak intensity (higher in regions with CCS), but not with its integrated intensity. This tendency may suggest that the narrower ammonia line widths in the less turbulent medium associated with younger cores may compensate for the differences in ammonia peak intensity, rendering differences in integrated intensity negligible. From the CCS detection rate we derive a lifetime of this molecule of ≃(0.7-3) × 10^4 yr in low-mass star-forming regions

A subset of low density granulocytes is associated with vascular calcification in chronic kidney disease patients

Inflammation is central to chronic kidney disease (CKD) pathogenesis and vascular outcomes, but the exact players remain unidentified. Since low density granulocytes (LDGs) are emerging mediators in inflammatory conditions, we aimed to evaluate whether LDGs may be altered in CKD and related to clinical outcomes as biomarkers. To his end, LDGs subsets were measured in peripheral blood by flow cytometry and confocal microscopy in 33 CKD patients undergoing peritoneal dialysis and 15 healthy controls (HC). Analyses were replicated in an additional cohort. DEF3 (marker of early granulopoiesis) gene expression on PBMCs was quantified by qPCR. Total CD15+ LDGs and both CD14lowCD16+ and CD14−CD16− subsets were expanded in CKD. The relative frequency of the CD14−CD16− subpopulation was higher among the CD15+ pool in CKD. This alteration was stable over-time. The increased CD14−CD16−CD15+ paralleled Kauppila scores and DEF3 expression, whereas no association was found with CD14lowCD16+ CD15+. Both subsets differed in their CD11b, CD10, CD35, CD31, CD62L, IFNAR1 and CD68 expression, FSC/SSC features and nuclear morphology, pointing to different origins and maturation status. In conclusion, LDGs were expanded in CKD showing a skewed distribution towards a CD14−CD16−CD15+ enrichment, in association with vascular calcification. DEF3 expression in PBMC can be a marker of LDG expansion.Fil: Rodríguez Carrio, Javier. Hospital Universitario Central de Asturias. Instituto de Investigación Sanitaria del Principado de Asturias (ISPA). Bone and Mineral Research Unit; España. Universidad de Oviedo; EspañaFil: Carrillo López, Natalia. Hospital Universitario Central de Asturias; EspañaFil: Ulloa, Catalina. Hospital Universitario Central de Asturias; EspañaFil: Seijo, Mariana. Hospital Universitario Central de Asturias; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; ArgentinaFil: Rodríguez García, Minerva. Hospital Universitario Central de Asturias; EspañaFil: Rodríguez Suárez, Carmen. Hospital Universitario Central de Asturias; EspañaFil: Díaz-Corte, Carmen. Hospital Universitario Central de Asturias; EspañaFil: Cannata Andía, Jorge B.. Universidad de Oviedo; España. Hospital Universitario Central de Asturias; EspañaFil: Suárez, Ana. Universidad de Oviedo; EspañaFil: Dusso, Adriana. Hospital Universitario Central de Asturias; Españ

Physicochemical characterization of blueberry (Vaccinium spp.) juices from 55 cultivars grown in Northern Spain

Blueberry (Vaccinium spp.) cultivation has experienced a notable increase both for its good organoleptic characteristics and the nutritional and functional properties of this berry. The aim of this study was the physicochemical characterization of blueberry juices obtained from 55 blueberry cultivars grown under the same environmental conditions for 2–4 years. The results provide a broad and robust database, both for the number of cultivars and the periods of monitoring thereof, in order to cover different aspects of blueberry processing, and more specifically, production of juices. Blueberries belonging to V. virgatum cultivars showed the higher values of total anthocyanin content, total phenolic content, antioxidant activity, soluble solids, and pH, and V. corymbosum cultivars the higher level of titratable acidity. Results also showed a high variability among cultivars. Observed variations can be used in plant breeding and classification of blueberry cultivars, at least, at the species level

Estudio de las Importaciones de Productos Naturales Vitamínicos A&E dentro del Mercado Ecuatoriano, Periodo 2013-2016

El presente trabajo tiene como fin demostrar el impacto que tuvo la implementación de las Salvaguardias dentro del periodo 2013 – 2016 en los Productos Naturales Vitamínicos A & E.  Se elaboraron cuadros comparativos de las importaciones de los productos naturales vitamínicos A & E antes y durante del periodo indicado dentro del trabajo.  Se realizó un análisis de las estadísticas oficiales.  Una vez obtenida la información se pudo indicar que las salvaguardias no fueron implementadas de una manera correcta para el caso de estos productos y que no hubo un informe que pudiera avalar la implementación de las mismas.  Finalmente se presentó una propuesta innovadora adicional para ser implementada en el mercado nacional y con esto poder fomentar más fuentes de trabajo

Validation of a gas chromatography-flame ionization method for quality control and spoilage detection in wine and cider

A GC-FID method for major volatile analysis in cider and wine was validated under the requirements of the ISO/IEC 17025 regulation using a split mode injection. This method presented a good linearity (R2>0.999, Cm>99%), a wide range of calibration, the maximum random errors for repeatability and intermediate precision were 5% and 8%, respectively, and the maximum limit of quantification and limit of detection were 14.1 mg l–1 and 4.6 mg l–1, respectively. Trueness, expressed as recovery (%), was successfully validated by means of two different methods, standard addition (92–110%) and comparison against reference materials (93–115%). Expanded uncertainty estimated at 95% confidence level ranged between 11% for methanol and 7% for allyl alcohol. The validated method was successfully applied for the analysis of major volatiles in ciders and wines, and to detect yeast and lactic acid bacteria spoilage

Are generalist batterers different from generally extra-family violent men? A study among imprisoned male violent offenders

Research on male batterers has found that in some cases of severe intimate partner violence (IPV) against women, male aggressors were also generally violent beyond the family realm. These findings have been used by researchers to illustrate the common etiology of both general and IPV. Using data from imprisoned male violent offenders, we analyzed the individual, family, and community characteristics of two groups of violent offenders: generalist batterers (GB) and generally extra-family violent men (GEVM). GB offenders had a judicial sentence on IPV-related offenses (gender violence according to the Spanish legislation), while GEVM offenders did not have any IPV-related judicial sentence. The sample includes 153 imprisoned male violent offenders of the Penitentiary Center of Villabona (Asturias, Spain). Sociodemographic measures, and criminal and justice official records of participants are available. Two groups of participants (GB and GEVM) distinction was done based on official records. Multivariate analyses of covariance (MANCOVA) was carried out to study differences between each group of participants in self-reported measures of personal, family, and community context variables. MANCOVA showed no statistical differences among the individual, family, and community characteristics of these two groups, giving empirical support to the theoretical view that general violence and IPV might share a common etiology. These results are discussed in light of the debate about the potentially common etiology of these two types of violence