2,375 research outputs found

    RDA: an innovation in cataloguing

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    With effect from 31 March 2013, Resource Description and Access (RDA) has become the cataloguing content standard used by the British Library and the Library of Congress. Concurrent with these institutions, other libraries, principally in the English-speaking world, have also adopted, or are planning to adopt, RDA. This article will discuss what RDA is, how and why it is an innovation in cataloguing, and will then examine its adoption by libraries. It will also address implications for library catalogues. Particular emphasis will be placed on the pattern of adoption, applying Everett Rogers' categorization to libraries as they implement RDA

    Improving performance in cataloguing and technical services workflows

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    Libraries are operating within what is currently a challenging economic climate. This looks set to continue for some years. This impact is being felt across the public and private sectors. Within the HE sector it is clear that further potentially far-reaching and possibly devastating funding cuts will happen. Universities have already made cuts which have impacted libraries in terms of staffing, services, information resources, opening hours, development plans and other ways. Challenging library budgets have lead libraries to consider the ways in which they operate at a process level. Focus is on doing more with less and in improving performance within, or with reduced, resources. This article describes how specific process improvement tools and techniques can be used to improve cataloguing and technical services workflows. It derives, in part, from practical experience of conduction a process review in this area within an academic research library context. The discussion is then applied at the level of bibliographic description, analysing how process improvement can be applied to the Functional Requirement for Bibliographic Records

    The Poet and the Temple of Delight : Allegory in Ode on Melancholy and Blake\u27s Songs

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    In the final stanza of John Keats’s “Ode on Melancholy,” there are capitalized emotions such as “Joy” that are characters within the poem. William Blake’s “Songs of Innocence” and “Songs of Experience” include personified emotions in much the same way. In this paper I will define allegory as using a “radical dispersonification” in which personified objects within the poem point to something abstract that exists on its own, outside the context of the poem. Given the similarity of Keats’s poem and Blake’s “Songs,” there is the possibility that as Romantics, Blake influenced Keats. In the sense that Blake’s “Songs” are ultimately a religious or political allegory, which Blake manifests as states of “Innocence” and “Experience,” and Keats’s poem is allegorical in the sense that it is about an abstract state called “Melancholy” that he has experienced as a poet

    Monday, September 17 and Urn [poems]

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    Stuart-Hunt recounts the difference in play styles of a four-year-old girl before and after losing her mother in the September 11 attack. This is followed by a poem she has written titled Urn

    Effect of distortion on the buckling strength of stiffened panels

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    This paper predicts the behaviour of stiffened plates with different distortion levels in order to address a rational structural design procedure as pre-existing and fabricationrelated (like weld-induced) initial geometrical distortion is of great importance in structural design point of view. The considered range of scantlings, the distortion typesand levels were chosen, based on panels used at BVT Surface Fleet Ltd., where the type 45 destroyer were under construction. An analytical relation is presented based on Perry's column approach to establish the variation of buckling strength against the geometrical distortion. A parametric form of non linear finite element analysis using ABAQUS has been carried out under axial loading condition to predict the behaviour and the buckling strength. The effect of residual stress is not considered in this study. A new strength parameter is proposed to represent buckling strength which takes into account the inelastic post-buckling behaviour of the structure. The results from FE analysis are plotted in non-dimensional terms and arrived at some important conclusions

    CydDC-mediated reductant export in Escherichia coli controls the transcriptional wiring of energy metabolism and combats nitrosative stress

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    The glutathione/cysteine exporter CydDC maintains redox balance in Escherichia coli. A cydD mutant strain was used to probe the influence of CydDC upon reduced thiol export, gene expression, metabolic perturbations, intracellular pH homeostasis, and tolerance to nitric oxide (NO). Loss of CydDC was found to decrease extracytoplasmic thiol levels, whereas overexpression diminished the cytoplasmic thiol content. Transcriptomic analysis revealed a dramatic up-regulation of protein chaperones, protein degradation (via phenylpropionate/phenylacetate catabolism), ?-oxidation of fatty acids, and genes involved in nitrate/nitrite reduction. 1H NMR metabolomics revealed elevated methionine and betaine and diminished acetate and NAD+ in cydD cells, which was consistent with the transcriptomics-based metabolic model. The growth rate and ?pH, however, were unaffected, although the cydD strain did exhibit sensitivity to the NO-releasing compound NOC-12. These observations are consistent with the hypothesis that the loss of CydDC-mediated reductant export promotes protein misfolding, adaptations to energy metabolism, and sensitivity to NO. The addition of both glutathione and cysteine to the medium was found to complement the loss of bd -type cytochrome synthesis in a cydD strain (a key component of the pleiotropic cydDC phenotype), providing the first direct evidence that CydDC substrates are able to restore the correct assembly of this respiratory oxidase. These data provide an insight into the metabolic flexibility of E. coli , highlight the importance of bacterial redox homeostasis during nitrosative stress, and report for the first time the ability of periplasmic low molecular weight thiols to restore haem incorporation into a cytochrome complex

    Do people with Parkinson’s disease look at task relevant stimuli when walking? An exploration of eye movements

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    Eye movements are impaired by Parkinson's disease (PD) although limited research has explored if PD affects the relevance of visual fixations when walking. Visual fixations may provide crucial contextual information for safe navigation and important insights into fall risk. This study aimed to: investigate visual fixations made while walking under a range of conditions in PD; identify their task relevance; and explore their relationship with clinical features. Thirty-eight people with mild-moderate PD and forty age-matched control participants completed a straight walk with (i) no additional stimuli and (ii) with additional stimuli (visual cues or a high contrast obstacle), whilst wearing a mobile eye-tracker. Fixations were extracted and classified by location and relevance. PD participants made proportionally fewer task-relevant fixations (floor, walls and additional stimuli ahead), caused by significantly more task-irrelevant fixations (floor, walls and ceiling away from waking path) during normal walking (p = 0.014). These group differences were not apparent with visual cues (p = 0.359). During obstacle crossing trials, PD made significantly more task-relevant fixations than controls (p = 0.007). Reduced bilateral visual acuity was associated with fewer fixations in PD. Our findings suggest that people with PD visually explore complex environments less efficiently likely owing to underlying PD pathology. Visual exploration improved with the addition of salient stimuli (for example visual cues or an obstacle) and thus developing and optimising visual interventions could prove critical to improving locomotor safety and reducing falls risk in home environments

    Injury induced activation of extracellular signal-regulated kinase (ERK) in the rat rostral ventromedial medulla (RVM) is age dependant and requires the lamina I projection pathway

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    Descending controls originating in part from the rostral ventromedial medulla (RVM) regulate the excitability of dorsal horn neurons and maintain peripheral pain states. Activation of extracellular signal regulated kinase (ERK) in RVM neurons has been shown following peripheral inflammation and is involved in generating the accompanying inflammatory hyperalgesia. Here, we show that spared nerve injury (SNI), a model of neuropathic pain, results in an increase in ERK activity in RVM neurons of adult rats 3 and 8 days following surgery. We carried out two experimental procedures to demonstrate that this increase in ERK activation was related to the increased mechanical sensitivity associated with SNI. First, we showed that lesions of the lamina I/III ascending pathway from the dorsal horn attenuated both mechanical hyperalgesia and ERK activation in the RVM. Second, we performed SNI in P10 rats. At this age, SNI did not result in mechanical hypersensitivity, as previously shown, and did not activate ERK in the RVM. Finally, the percentage of pERK expressing neurones that were also serotonergic was always around 60%, independent of pain state and age, indicating an important role for serotonin in descending controls of pain states

    Design Entrepreneurship in Innovation

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    The paper demonstrates the need for an entrepreneurial attitude and competence in designers of today in order to ensure innovation. The paper considers evidence from four design innovation case studies to explore the relationship between design capabilities and the wider conditions necessary for innovation. All four case studies have been conducted in collaboration with commercial organisations seeking innovation, and designers and academics based in a university in the United Kingdom. First, a review of design’s capabilities is presented from the literature. Second, evidence from each case study is mapped to the UK Design Council’s popular model of design process: the double diamond. This allows findings across the four cases to be compared and discussed, considering how design’s capabilities contribute to the conditions necessary to transform design effort into innovation. Third, the role of design within the ‘define’ stage of the double diamond is articulated. The initial findings state that the lack of connector-­ integrator capability in designers during the ‘define’ phase lead to weak interpretation of the problem space, and consequently contributed to design’s inability to convert ideas into real products in the ‘delivery’ phase. The paper concludes that for design to effectively drive innovation it needs to secure entrepreneurial support i.e. with an appetite for risk/reward; in the early part of the design process

    Low-cost automated vectors and modular environmental sensors for plant phenotyping

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    © 2020 by the authors. Licensee MDPI, Basel, Switzerland. High-throughput plant phenotyping in controlled environments (growth chambers and glasshouses) is often delivered via large, expensive installations, leading to limited access and the increased relevance of “affordable phenotyping” solutions. We present two robot vectors for automated plant phenotyping under controlled conditions. Using 3D-printed components and readily-available hardware and electronic components, these designs are inexpensive, flexible and easily modified to multiple tasks. We present a design for a thermal imaging robot for high-precision time-lapse imaging of canopies and a Plate Imager for high-throughput phenotyping of roots and shoots of plants grown on media plates. Phenotyping in controlled conditions requires multi-position spatial and temporal monitoring of environmental conditions. We also present a low-cost sensor platform for environmental monitoring based on inexpensive sensors, microcontrollers and internet-of-things (IoT) protocols
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