Baltimore Law Clubs: A Tradition Promoting the Integrity of the Bar Through Scholarship and Congeniality

Since before the civil war, lawyers and judges in Baltimore have had a tendency to organize informal, intimate, and exclusive clubs for the purpose of promoting congeniality and scholarship.1 Although this Anglo-American tradition traces back to as early as the sixteenth century,2 the institution of law clubs in the United States appears to have been a unique, local phenomenon until the 1960s and 1970s.3 Today, this tradition continues in Baltimore City, which currently plays host to no fewer than eight individual law clubs, with many more existing throughout the state. These law clubs offer their members the opportunity to pursue scholarly endeavors while also providing a social outlet for members of the bench and bar alike. While the members of these organizations certainly realize the intrinsic benefits attendant to membership, Baltimore’s law clubs also benefit the legal profession by promoting scholarship and congeniality

“Smart” Foams for Active Absorption of Sound (written version)

A porous layer can absorb a significant amount of acoustic energy only if its thickness is comparable to the wavelength of the incident sound. Thus a porous layer inevitably becomes a less effective sound absorber as the frequency is decreased. In this paper, it will be shown through theoretical calculations that the low frequency performance of a finite-depth layer of elastic porous material may be enhanced by applying an appropriate force to the solid phase at the front surface of the layer. In particular, it will be shown that at any angle of incidence the solid phase may be forced so as to create a perfect impedance match with an incident plane wave, thus causing the sound to be completely absorbed. Note that the success of the approach suggested here requires a significant degree of coupling between the motion of the solid and fluid phases of the porous material. Thus, it may be expected that partially reticulated, polyurethane foams will be susceptible to this approach owing to the degree of viscous and inertial coupling between their fluid and solid phases

Syncope and the drive towards minimization in Colloquial Bamana

Data from two varieties of Bamana, a Mande language spoken in West Africa, illustrate that permissible syllable shapes vary between the two types. A comparison of Classic Bamana spoken in Segou, Mali and that spoken by a younger cohort of individuals in the Malian capital, Bamako, reveals that the latter variety is synchronically developing complex CCV and CVC syllable shapes, whereas the classical variety permits only maximal CV syllables. We posit that the development of these syllable shapes represents an overall drive towards word minimization in this variety of the language. This study formalizes minimization in Colloquial Bamana in an optimality theoretic framework and illustrates the support that these developing processes in Bamana provide for the Split Margin Approach to the syllable, developed in Baertsch (2002). Preferential deletion patterns, the role of phonotactics in driving these patterns, and other processes interacting with and/or preventing syncope from occurring are also explored.National Institutes of Health DC00433, RR7031K, DC00076, DC001694 (PI: Gierut

Fundamentos filosóficos del derecho penal

- Divulgação dos SUMÁRIOS das obras recentemente incorporadas ao acervo da Biblioteca Ministro Oscar Saraiva do STJ. Em respeito à Lei de Direitos Autorais, não disponibilizamos a obra na íntegra.- Localização na estante: 343:340.12 F981f- Coordenado por: Aluisio Gonçalves de Castro Mendes e Guilherme Calmon Nogueira da Gam

An Approximate Large NN Method for Lattice Chiral Models

An approximation is used that permits one to explicitly solve the two-point Schwinger-Dyson equations of the U(N) lattice chiral models. The approximate solution correctly predicts a phase transition for dimensions $d$ greater than two. For $d \le 2$, the system is in a single disordered phase with a mass gap. The method reproduces known $N=\infty$ results well for $d=1$. For $d=2$, there is a moderate difference with $N=\infty$ results only in the intermediate coupling constant region.Comment: Latex file, 19 page

Infrared spectra and fragmentation dynamics of isotopologue-selective mixed-ligand complexes †

Isolated mixed-ligand complexes provide tractable model systems in which to study competitive and cooperative binding effects as well as controlled energy flow. Here, we report spectroscopic and isotopologue-selective infrared photofragmentation dynamics of mixed gas-phase Au(12/13CO)n(N2O)m+ complexes. The rich infrared action spectra, which are reproduced well using simulations of calculated lowest energy structures, clarify previous ambiguities in the assignment of vibrational bands, especially accidental coincidence of CO and N2O bands. The fragmentation dynamics exhibit the same unexpected behaviour as reported previously in which, once CO loss channels are energetically accessible, these dominate the fragmentation branching ratios, despite the much lower binding energy of N2O. We have investigated the dynamics computationally by considering anharmonic couplings between a relevant subset of normal modes involving both ligand stretch and intermolecular modes. Discrepancies between correlated and uncorrelated model fit to the ab initio potential energy curves are quantified using a Boltzmann sampled root mean squared deviation providing insight into efficiency of vibrational energy transfer between high frequency ligand stretches and the softer intermolecular modes which break during fragmentation

A Bayesian elicitation of veterinary beliefs regarding systemic dry cow therapy: variation and importance for clinical trial design

The two key aims of this research were: (i) to conduct a probabilistic elicitation to quantify the variation in veterinarians’ beliefs regarding the efficacy of systemic antibiotics when used as an adjunct to intra-mammary dry cow therapy and (ii) to investigate (in a Bayesian statistical framework) the strength of future research evidence required (in theory) to change the beliefs of practising veterinary surgeons regarding the efficacy of systemic antibiotics, given their current clinical beliefs. The beliefs of 24 veterinarians in 5 practices in England were quantified as probability density functions. Classic multidimensional scaling revealed major variations in beliefs both within and between veterinary practices which included: confident optimism, confident pessimism and considerable uncertainty. Of the 9 veterinarians interviewed holding further cattle qualifications, 6 shared a confidently pessimistic belief in the efficacy of systemic therapy and whilst 2 were more optimistic, they were also more uncertain. A Bayesian model based on a synthetic dataset from a randomised clinical trial (showing no benefit with systemic therapy) predicted how each of the 24 veterinarians’ prior beliefs would alter as the size of the clinical trial increased, assuming that practitioners would update their beliefs rationally in accordance with Bayes’ theorem. The study demonstrated the usefulness of probabilistic elicitation for evaluating the diversity and strength of practitioners’ beliefs. The major variation in beliefs observed raises interest in the veterinary profession's approach to prescribing essential medicines. Results illustrate the importance of eliciting prior beliefs when designing clinical trials in order to increase the chance that trial data are of sufficient strength to alter the clinical beliefs of practitioners and do not merely serve to satisfy researchers

Role of Akt signaling pathway regulation in the speckled mousebird (Colius striatus) during torpor displays tissue specific responses

Pronounced heterothermic responses are relatively rare among birds. Along with taxa such as hummingbirds and caprimulgids, the order Coliiformes (mousebirds) is known to possess the physiological capacity for torpor. During torpor, body temperature is greatly reduced and a bird becomes unresponsive to external stimuli until ambient temperatures return to more favorable conditions. Under such conditions, these birds are forced to rely only on their internal fuel storage for energy and show great reduction in metabolic rates by decreasing energy-expensive processes. This study investigated the role of the key insulin-Akt signaling kinase pathway involved in regulating energy metabolism and protein translation in the liver, kidney, heart, skeletal muscle, and brain of the speckled mousebird (Colius striatus). The degree of phosphorylation of well-conserved target residues with important regulatory function was examined in both the euthermic control and torpid birds. The results demonstrated marked differences in responses between the tissues with decreases in RPS6 S235/236 phosphorylation in the kidney (0.52 fold of euthermic) and muscle (0.29 fold of euthermic) as well as decreases in GS3K3β S9 in muscle (0.60 fold of euthermic) and GSK3α S21 (0.71 fold of euthermic) phosphorylation in kidney during torpor, suggesting a downregulation of this pathway. Interestingly, the liver demonstrated an increase in RPS6 S235/236 (2.89 fold increase) and P70S6K T412 (1.44 fold increase) phosphorylation in the torpor group suggesting that protein translation is maintained in this tissue. This study demonstrates that avian torpor is a complex phenomenon and alterations in this signaling pathway follow a tissue specific pattern.Supplementary material 1: Western blots for quantifying the relative levels of phosphorylated S209 eIF-4E and total mTOR levels in euthermic and torpid C. striatus tissuesSupplementary material 2: Sequence alignment of mousebird protein targets involved in the Akt signaling kinase pathway and protein translation in comparison to human sequencesThe Natural Sciences and Engineering Research Council of Canada (NSERC), the Canada Research Chair in Molecular Physiology, an NSERC funded Alexander Graham Bell Canada Graduate Scholarship, an Ontario Graduate Scholarship and the National Research Foundation of South Africa.https://www.elsevier.com/locate/cellsig2021-11-01hj2020Zoology and Entomolog

Phosphorylation status of pyruvate dehydrogenase in the mousebird Colius striatus undergoing torpor

DATA AVAILABILITY STATEMENT : Data available on request from the authors.Torpor is a heterothermic response that occurs in some animals to reduce metabolic expenditure. The speckled mousebird (Colius striatus) belongs to one of the few avian taxa possessing the capacity for pronounced torpor, entering a hypometabolic state with concomitant decreases in body temperature in response to reduced food access or elevated thermoregulatory energy requirements. The pyruvate dehydrogenase complex (PDC) is a crucial site regulating metabolism by bridging glycolysis and the Krebs cycle. Three highly conserved phosphorylation sites are found within the E1 enzyme of the complex that inhibit PDC activity and reduce the flow of carbohydrate substrates into the mitochondria. The current study demonstrates a marked increase in S232 phosphorylation during torpor in liver, heart, and skeletal muscle of C. striatus. The increase in S232 phosphorylation during torpor was particularly notable in skeletal muscle where levels were ~49-fold higher in torpid birds compared to controls. This was in contrast to the other two phosphorylation sites (S293 and S300) which remained consistently phosphorylated regardless of tissue. The relevant PDH kinase (PDHK1) known to phosphorylate S232 was found to be substantially upregulated (~5-fold change) in the muscle during torpor as well as increasing moderately in the liver (~2.2-fold increase). Additionally, in the heart, a slight (~23%) decrease in total PDH levels was noted. Taken together the phosphorylation changes in PDH suggest that inhibition of the complex is a common feature across several tissues in the mousebird during torpor and that this regulation is mediated at a specific residue.Natural Sciences and Engineering Research Council of Canada and National Research Foundation of South Africa.http://wileyonlinelibrary.com/journal/jezhj2023Zoology and Entomolog

Collapse to Black Holes in Brans-Dicke Theory: II. Comparison with General Relativity

We discuss a number of long-standing theoretical questions about collapse to black holes in the Brans-Dicke theory of gravitation. Using a new numerical code, we show that Oppenheimer-Snyder collapse in this theory produces black holes that are identical to those of general relativity in final equilibrium, but are quite different from those of general relativity during dynamical evolution. We find that there are epochs during which the apparent horizon of such a black hole passes {\it outside\/} the event horizon, and that the surface area of the event horizon {\it decreases\/} with time. This behavior is possible because theorems which prove otherwise assume $R_{ab}l^al^b \ge 0$ for all null vectors $l^a$. We show that dynamical spacetimes in Brans-Dicke theory can violate this inequality, even in vacuum, for any value of $\omega$.Comment: 24 pages including figures, uuencoded gz-compressed postscript, Submitted to Phys Rev