Single-trial multiwavelet coherence in application to neurophysiological time series

A method of single-trial coherence analysis is presented, through the application of continuous muldwavelets. Multiwavelets allow the construction of spectra and bivariate statistics such as coherence within single trials. Spectral estimates are made consistent through optimal time-frequency localization and smoothing. The use of multiwavelets is considered along with an alternative single-trial method prevalent in the literature, with the focus being on statistical, interpretive and computational aspects. The multiwavelet approach is shown to possess many desirable properties, including optimal conditioning, statistical descriptions and computational efficiency. The methods. are then applied to bivariate surrogate and neurophysiological data for calibration and comparative study. Neurophysiological data were recorded intracellularly from two spinal motoneurones innervating the posterior,biceps muscle during fictive locomotion in the decerebrated cat

CyberGuarder: a virtualization security assurance architecture for green cloud computing

Cloud Computing, Green Computing, Virtualization, Virtual Security Appliance, Security Isolation

Immunity to self co-generates regulatory T cells

Immune responses to self are kept in check by tolerance mechanisms, including suppression by regulatory T cells (Tregs). The defective generation of Tregs specific for self-antigens may lead to autoimmune disease. We identified a novel population of human CD4^+^ Tregs, characterized by high surface expression of CD52, which is co-generated in response to autoantigen. Blood CD4^+^CD52^hi^ T cells were generated preferentially in response to low-dose autoantigen and suppressed proliferation and interferon-[gamma] production by other T cells. Depletion of resting CD4^+^CD52^hi^ T cells enhanced the T-cell response to autoantigen. CD4^+^CD52^hi^ Tregs were neither derived from nor distinguished by markers of conventional resting CD4^+^CD25^+^ Tregs. In response to the pancreatic islet autoantigens glutamic acid decarboxylase, the generation of CD4^+^CD52^hi^ Tregs was impaired in individuals with and at-risk for type 1 diabetes, compared to healthy controls and individuals with type 2 diabetes. CD4^+^CD52^hi^ Tregs co-generated to self-antigen may therefore contribute to immune homeostasis and protect against autoimmune disease

Literature Themes from Five Decades of Agricultural Communications Publications

The discipline of agricultural communications has been developing for nearly two centuries. As the discipline has adapted, professional organizations such as the American Association of `Agricultural College Editors (AAACE) and the Association for Communication Excellence in Agriculture, Natural Resources, and Life and Human Sciences (ACE) have published literature representative of the topics and issues that have impacted the discipline through magazines and journals such as the AAACE, ACE Quarterly, and the Journal of Applied Communications (JAC). The purpose of this study was to review the literature published in AAACE, ACE Quarterly, and JAC from 1968-2015 to identify primary and secondary literature themes. There were 13 emergent themes identified. The most prolific primary theme identified was Channel Development, Use or Research while the most prolific secondary theme identified was Educating Professionals. A count of the number of articles classified as “professional development” and “research” revealed a shift in the focus in the journal outlets. In earlier years, the discipline focused mainly on professional development articles (AAACE and ACE Quarterly), but transitioned almost completely to research (JAC). This research acknowledges that the discipline has experienced significant literary shifts and provides a recommendation for further research in audience analysis of the literature coming from the journals of the discipline