How Racially Diverse Schools and Classrooms Can Benefit All Students

A growing number of parents, university officials, and employers want our elementary and secondary schools to better prepare students for our increasingly racially and ethnically diverse society and the global economy. But for reasons we cannot explain, the demands of this large segment of Americans have yet to resonate with most of our federal, state, or local policymakers. Instead, over the past forty years, these policy makers have completely ignored issues of racial segregation while focusing almost exclusively on high-stakes accountability, even as our schools have become increasingly segregated and unequal.This report argues that, as our K -- 12 student population becomes more racially and ethnically diverse, the time is right for our political leaders to pay more attention to the evidence, intuition, and common sense that supports the importance of racially and ethnically diverse educational settings to prepare the next generation. It highlights in particular the large body of research that demonstrates the important educational benefits -- cognitive, social, and emotional -- for all students who interact with classmates from different backgrounds, cultures, and orientations to the world. This research legitimizes the intuition of millions of Americans who recognize that, as the nation becomes more racially and ethnically complex, our schools should reflect that diversity and tap into the benefits of these more diverse schools to better educate all our students for the twenty-first century.The advocates of racially integrated schools understand that much of the recent racial tension and unrest in this nation -- from Ferguson to Baltimore to Staten Island -- may well have been avoided if more children had attended schools that taught them to address implicit biases related to racial, ethnic, and cultural differences. This report supports this argument beyond any reasonable doubt

Direct Inhibition of T-Cell Responses by the Cryptococcus Capsular Polysaccharide Glucuronoxylomannan

The major virulence factor of the pathogenic fungi Cryptococcus neoformans and C. gattii is the capsule. Glucuronoxylomannan (GXM), the major component of the capsule, is a high-molecular-weight polysaccharide that is shed during cryptococcosis and can persist in patients after successful antifungal therapy. Due to the importance of T cells in the anticryptococcal response, we studied the effect of GXM on the ability of dendritic cells (DCs) to initiate a T-cell response. GXM inhibited the activation of cryptococcal mannoprotein-specific hybridoma T cells and the proliferation of OVA-specific OT-II T cells when murine bone marrow-derived DCs were used as antigen-presenting cells. Inhibition of OT-II T-cell proliferation was observed when either OVA protein or OVA323-339 peptide was used as antigen, indicating GXM did not merely prevent antigen uptake or processing. We found that DCs internalize GXM progressively over time; however, the suppressive effect did not require DCs, as GXM directly inhibited T-cell proliferation induced by anti-CD3 antibody, concanavalin A, or phorbol-12-myristate-13-acetate/ionomycin. Analysis of T-cell viability revealed that the reduced proliferation in the presence of GXM was not the result of increased cell death. GXM isolated from each of the four major cryptococcal serotypes inhibited the proliferation of human peripheral blood mononuclear cells stimulated with tetanus toxoid. Thus, we have defined a new mechanism by which GXM can impart virulence: direct inhibition of T-cell proliferation. In patients with cryptococcosis, this could impair optimal cell-mediated immune responses, thereby contributing to the persistence of cryptococcal infections. SynopsisInfections due to the pathogenic yeast Cryptococcus are a significant cause of morbidity and mortality in persons with impaired T-cell functions, particularly those with AIDS. The major virulence factor of Cryptococcus is its capsule, which is composed primarily of the polysaccharide glucuronoxylomannan (GXM). The capsule not only surrounds the organism but also is shed during cryptococcosis. GXM is taken up by macrophages in vitro and in vivo; however, little is known about the interaction between GXM and dendritic cells, which are the most potent cells capable of activating T cells. Because of the importance of T cells in the anticryptococcal response, the authors investigated the effect of GXM on the ability of dendritic cells to initiate a T-cell response. They found the polysaccharide was internalized by dendritic cells and inhibited antigen-specific T-cell responses. Furthermore, GXM had a direct, inhibitory effect on T-cell proliferation, independent of the effect on dendritic cells. These findings may help explain the persistence of cryptococcal infections and suggest that GXM could be therapeutic in situations where suppression of T-cell responses is desired.National Institutes of Health (R01 AI25780, R01 AI066087, R01 AI37532

Meaning-based machine learning for information assurance

AbstractThis paper presents meaning-based machine learning, the use of semantically meaningful input data into machine learning systems in order to produce output that is meaningful to a human user where the semantic input comes from the Ontological Semantics Technology theory of natural language processing. How to bridge from knowledge-based natural language processing architectures to traditional machine learning systems is described to include high-level descriptions of the steps taken. These meaning-based machine learning systems are then applied to problems in information assurance and security that remain unsolved and feature large amounts of natural language text

Commodification of the Information Profession: A Critique of Higher Education Under Neoliberalism

The structures that govern society’s understanding of information have been reorganised under a neoliberal worldview to allow information to appear and function as a commodity. This has implications for the professional ethics of library and information labour, and the need for critical reflexivity in library and information praxes is not being met. A lack of theoretical understanding of these issues means that the political interests governing decision-making are going unchallenged, for example the UK government’s specific framing of open access to research. We argue that building stronger, community oriented praxes of critical depth can serve as a resilient challenge to the neoliberal politics of the current higher education system in the UK and beyond. Critical information literacy offers a proactive, reflexive and hopeful strategy to challenge hegemonic assumptions about information as a commodity

Understanding how law enforcement agencies share information in an intelligence-led environment: How operational context influences different approaches

PurposeThe importance of multi-agency information sharing is recognised as central to tackling crime and disorder in an intelligence-driven environment. However, whilst technology can facilitate and enhance this process, barriers to effective agency information exchange are consistently reported. This paper aims to categorise how information sharing takes place in a law enforcement operational setting and whether there is scope to improve the process.Design/methodology/approachThere were two stages to the method; firstly, a select group of practitioners with intelligence-related experience (n = 28) were interviewed to identify the most common approaches to operational information sharing. This generated a categorisation model, which was tested with a larger group of practitioners (n = 73). A mixed-methods approach was adopted.FindingsThe research found consensus surrounding four different approaches to information sharing, labelled as: (1) inform and request, (2) meet and share, (3) customised database and (4) integrated systems. These are used at various levels of frequency, dependent on the operational context.Originality/valueThis research provides original evidence-based research to show law enforcement practitioners vary in the way they share information. By demystifying and categorising the process, it provides understanding for practitioners, policymakers and researchers, allowing barriers to be more readily tackled in a much more cost-effective manner

Helping communities to help themselves : the case of Eleos.

Current literature asserts that recipients of social services in South Africa are characterised by their history, race and ethnicity (Pharoah, 2007; Scheurmans and Visser, 2005). This study attempted to either confirm or challenge such assertions, based on the experiences and strategies implemented by Eleos, a unique non‐ profit organisation that is entrenched in communities that are diverse. The primary aim of this study was to explore the ethos of Eleos, in its interventions to address poverty in underprivileged communities. The study drew from two groups of participants. The first sample of eight participants was drawn from the two beneficiary communities of Eleos. One project is located in Booysens West and the other in Danville. The second group of participants were key informants who were drawn from the management committee as well as representatives of the individual projects. The research instruments took the form of two different semi‐structured interview schedules with open‐ended questions. One for key informants and another for beneficiaries. The research design that was used in the study was the case study design and was exploratory in nature. The collected data was transcribed and analysed using ‘thematic content analysis’ or ‘conceptual analysis’. Main findings indicated that donors seemed to impose a more radicalized view of the world, more so than the beneficiaries and organisation it self

Elevating the Voices for All Learners through Shared Stories of Science Learning

This study examines the science learning experiences across the lifespan of two groups of college students: adults with intellectual and/or developmental disabilities in a post-secondary inclusive program, and adults in a preservice secondary education teacher candidate program. Data, in the form of personal narrative science stories were collected using a paired-interview approach in which students from each group interviewed one another about their science learning across their lifespans, and recorded responses using an online form. Across the stories, several clear themes emerged. Similarities and differences were found across and within the groups and are shared in a narrative format. Trends that emerged both across and within groups are shared, and recommendations are made for current and future teachers for best practices in teaching science to all students, including those with a variety of disabilities

Variations in area-level disadvantage of Australian registered fitness trainers usual training locations

BACKGROUND: Leisure-time physical activity and strength training participation levels are low and socioeconomically distributed. Fitness trainers (e.g. gym/group instructors) may have a role in increasing these participation levels. However, it is not known whether the training location and characteristics of Australian fitness trainers vary between areas that differ in socioeconomic status. METHODS: In 2014, a sample of 1,189 Australian trainers completed an online survey with questions about personal and fitness industry-related characteristics (e.g. qualifications, setting, and experience) and postcode of their usual training location. The Australian Bureau of Statistics \u27Index of Relative Socioeconomic Disadvantage\u27 (IRSD) was matched to training location and used to assess where fitness professionals trained and whether their experience, qualification level and delivery methods differed by area-level disadvantage. Linear regression analysis was used to examine the relationship between IRSD score and selected characteristics adjusting for covariates (e.g. sex, age). RESULTS: Overall, 47 % of respondents worked in areas within the three least-disadvantaged deciles. In contrast, only 14.8 % worked in the three most-disadvantaged deciles. In adjusted regression models, fitness industry qualification was positively associated with a higher IRSD score (i.e. working in the least-disadvantaged areas) (Cert III: ref; Cert IV β:13.44 [95 % CI 3.86-23.02]; Diploma β:15.77 [95 % CI: 2.17-29.37]; Undergraduate β:23.14 [95 % CI: 9.41-36.86]). CONCLUSIONS: Fewer Australian fitness trainers work in areas with high levels of socioeconomic disadvantaged areas than in areas with low levels of disadvantage. A higher level of fitness industry qualifications was associated with working in areas with lower levels of disadvantage. Future research should explore the effectiveness of providing incentives that encourage more fitness trainers and those with higher qualifications to work in more socioeconomically disadvantaged areas