121 research outputs found
Complementary Algorithms For Tableaux
We study four operations defined on pairs of tableaux. Algorithms for the
first three involve the familiar procedures of jeu de taquin, row insertion,
and column insertion. The fourth operation, hopscotch, is new, although
specialised versions have appeared previously. Like the other three operations,
this new operation may be computed with a set of local rules in a growth
diagram, and it preserves Knuth equivalence class. Each of these four
operations gives rise to an a priori distinct theory of dual equivalence. We
show that these four theories coincide. The four operations are linked via the
involutive tableau operations of complementation and conjugation.Comment: 29 pages, 52 .eps files for figures, JCTA, to appea
Damsīrī
Aṛ-ṛays al-ḥajj Muhamad ibn Laḥsen ad-Damsiri fut l’un des plus important chanteurs-poètes traditionnels (ṛṛays, pluriel ṛṛways) contemporains dans la région du Maroc de parler tachelγiyt. Ce fils d’un boucher naquit en 1936 à Tamsoult dans la région de Demsira, mais il vécut la plus grande partie de sa vie à Casablanca. Son nom de famille était Ajaḥud. Il reçut un enseignement coranique en vue d’enseigner à son tour le Coran mais il ne professa jamais. Il commença à devenir célèbre en 1963 e..
In de schaduw van het Arabisch: Over niet-arabische talen en culturen in Noord-Afrika en het Midden-Oosten
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A short delirium caregiver questionnaire for triage of elderly outpatients with cognitive impairment:a development and test accuracy study
OBJECTIVES: Delirium is often missed in older outpatients. Caregivers can give valuable information that might improve identification rates. The aim of this study was to develop a short and sensitive delirium caregiver questionnaire (DCQ) for triage of elderly outpatients with cognitive impairment by telephone.DESIGN, SETTING, AND PARTICIPANTS: The pilot questionnaire was administered to 112 caregivers of patients who were referred for dementia screening to our clinic for geriatric psychiatry, and the final DCQ to 234 other caregivers.MEASUREMENTS: In phase I (2013-2014), we tested a pilot questionnaire with 17 items. Health professionals who established delirium diagnoses were blinded to the results. We then used the results and other information available at referral to construct the final DCQ with seven items. During phase II (2015-2016), we investigated the test accuracy of the final DCQ in a subsequent cohort. In both phases, the patients received a structured diagnostic workup. Time between referral and first visit was a secondary outcome.RESULTS: The final DCQ consisted of the following items: emergency visit required, sleeping disorder, fluctuating course, hallucinations, suspicious thoughts, previous delirium, and recent discharge from hospital. DCQ results indicated that urgent intake was required in 85 of 234 patients. Sensitivity was 73.5% (95% CI: 58.9-85.1%) and specificity 73.5% (95% CI: 66.5-79.7%). The mean number of days to first visit dropped from 31.6 to 11.2 in delirious patients (p = 0.001).CONCLUSIONS: Triage with the easy-to-use DCQ among patients referred for cognitive screening leads to earlier assessment and higher detection rates of delirium.</p
Brown-Vialetto-Van Laere and Fazio Londe syndrome is associated with a riboflavin transporter defect mimicking mild MADD: a new inborn error of metabolism with potential treatment
We report on three patients (two siblings and one unrelated) presenting in infancy with progressive muscle weakness and paralysis of the diaphragm. Metabolic studies revealed a profile of plasma acylcarnitines and urine organic acids suggestive of a mild form of the multiple acyl-CoA dehydrogenation defect (MADD, ethylmalonic/adipic acid syndrome). Subsequently, a profound flavin deficiency in spite of a normal dietary riboflavin intake was established in the plasma of all three children, suggesting a riboflavin transporter defect. Genetic analysis of these patients demonstrated mutations in the C20orf54 gene which encodes the human homolog of a rat riboflavin transporter. This gene was recently implicated in the Brown-Vialetto-Van Laere syndrome, a rare neurological disorder which may either present in infancy with neurological deterioration with hypotonia, respiratory insufficiency and early death, or later in life with deafness and progressive ponto-bulbar palsy. Supplementation of riboflavin rapidly improved the clinical symptoms as well as the biochemical abnormalities in our patients, demonstrating that high dose riboflavin is a potential treatment for the Brown-Vialetto-Van Laere syndrome as well as for the Fazio Londe syndrome which is considered to be the same disease entity without the deafnes
Role of natriuretic peptides in the diagnosis and treatment of patients with carcinoid heart disease
The Role of CD44 in the Pathogenesis, Diagnosis, and Therapy of Gastric Cancer
CD44 is a transmembrane glycoprotein and surface receptor for hyaluronan that is involved in the response of cells to their microenvironment. CD44 splice variants play roles in carcinogenesis, differentiation, and lymph node metastasis and are predictive of the prognosis for various carcinomas, including gastric cancer. Current data suggest that gastric tissue stem cells and gastric cancer stem cells both express the splice variant, CD44v9. Overall, the data regarding the alterations that occur in CD44 and its splice variants in response to acute and chronic infection with Helicobacter pylori are scant and poorly elucidated in terms of possible changes in expression that occur in gastric cancer precursor lesions, such as chronic atrophic gastritis, pyloric metaplasia and intestinal metaplasia. In this study, we discuss the available data and suggest which new data would likely be useful in clinical practice. We also discuss the potential for CD44-targeted therapeutic strategies in gastric cancer. CD44 and its splice variants are positively associated with the initiation and progression of gastric cancer and may also play important roles in diagnosis, therapy and prognosis. CD44 research has been active but fragmented, and it may offer new therapeutic approaches to gastric cancer
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