Structure and Sedimentology of Siluro- Devonian Between Edmunston and Grand Falls, New Brunswick

Guidebook to the geology of Northeastern Maine and neighboring New Brunswick: The 72nd annual meeting of the New England Intercollegiate Geological Conference, Presque Isle, Maine, October 10-13, 1980: Trip C-

The Influence of Large Prestrains on Dynamic Properties of Sand

The development of the UMR Resonant Column/Torsional simple Shear device has provided the means to evaluate high and low amplitude shear moduli on a single sand specimen. Results of cyclic torsional simple shear tests showed that progressive strain increases w1th the cyclic strain amplitude and the number of cycles and decreases with density of the sand. Large accumulated prestrains were found to decrease the maximum dynamic shear modulus by 30 to 35%

Characterization of the spore surface and exosporium proteins of Clostridium sporogenes; implications for Clostridium botulinum group I strains.

Clostridium sporogenes is a non-pathogenic close relative and surrogate for Group I (proteolytic) neurotoxin-producing Clostridium botulinum strains. The exosporium, the sac-like outermost layer of spores of these species, is likely to contribute to adhesion, dissemination, and virulence. A paracrystalline array, hairy nap, and several appendages were detected in the exosporium of C. sporogenes strain NCIMB 701792 by EM and AFM. The protein composition of purified exosporium was explored by LC-MS/MS of tryptic peptides from major individual SDS-PAGE-separated protein bands, and from bulk exosporium. Two high molecular weight protein bands both contained the same protein with a collagen-like repeat domain, the probable constituent of the hairy nap, as well as cysteine-rich proteins CsxA and CsxB. A third cysteine-rich protein (CsxC) was also identified. These three proteins are also encoded in C. botulinum Prevot 594, and homologues (75-100% amino acid identity) are encoded in many other Group I strains. This work provides the first insight into the likely composition and organization of the exosporium of Group I C. botulinum spores

Endothelial Progenitor Cells Enter the Aging Arena

Age is a significant risk factor for the development of vascular diseases, such as atherosclerosis. Although pharmacological treatments, including statins and anti-hypertensive drugs, have improved the prognosis for patients with cardiovascular disease, it remains a leading cause of mortality in those aged 65 years and over. Furthermore, given the increased life expectancy of the population in developed countries, there is a clear need for alternative treatment strategies. Consequently, the relationship between aging and progenitor cell-mediated repair is of great interest. Endothelial progenitor cells (EPCs) play an integral role in the cellular repair mechanisms for endothelial regeneration and maintenance. However, EPCs are subject to age-associated changes that diminish their number in circulation and function, thereby enhancing vascular disease risk. A great deal of research is aimed at developing strategies to harness the regenerative capacity of these cells. In this review, we discuss the current understanding of the cells termed “EPCs,” examine the impact of age on EPC-mediated repair and identify therapeutic targets with potential for attenuating the age-related decline in vascular health via beneficial actions on EPCs

Endo-cannibalism in the making of a recent British ancestor

Following his death in 1975, the ashes of Wally Hope, founder of Stonehenge People's Free Festival, were scattered in the centre of Stonehenge. When a child tasted the ashes the rest of the group followed this lead. In the following decades, as the festival increasingly became the site of contest about British heritage and culture, the story of Wally's ashes was told at significant times. His name continues to be invoked at gatherings today. This paper discusses these events as 'the making of an ancestor', and explores wider contexts in which they might be understood. These include Druidic involvement in the revival of cremation, Amazonian bone-ash endo-cannibalism, and popular means of speaking of and to dead relatives. In addition to considering the role of 'ancestors' in contemporary Britain, the paper contributes to considerations of 'ancestry' as a different way of being dead, of a particular moment in the evolution of an alternative religious neo-tribal movement, of the meanings of 'cannibalism', and of the ways in which human remains might be treated by the bereaved and by various other interested parties

Modern Contraceptive and Dual Method Use among HIV-Infected Women in Lusaka, Zambia

HIV-infected women in sub-Saharan Africa are at substantial risk of unintended pregnancy and sexually transmitted infections (STIs). Linkages between HIV and reproductive health services are advocated. We describe implementation of a reproductive health counseling intervention in 16 HIV clinics in Lusaka, Zambia. Between November 2009 and November 2010, 18,407 women on antiretroviral treatment (ART) were counseled. The median age was 34.6 years (interquartile range (IQR): 29.9–39.7), and 60.1% of women were married. The median CD4+ cell count was 394 cells/uL (IQR: 256–558). Of the women counseled, 10,904 (59.2%) reported current modern contraceptive use. Among contraceptive users, only 17.7% reported dual method use. After counseling, 737 of 7,503 women not previously using modern contraception desired family planning referrals, and 61.6% of these women successfully accessed services within 90 days. Unmet contraceptive need remains high among HIV-infected women. Additional efforts are needed to promote reproductive health, particularly dual method use

The economics of protecting tiger populations: linking household behavior to poaching and prey depletion

The tiger ( Panthera tigris ) is classified as endangered and populations continue to decline. This paper presents a formal economic analysis of the two most imminent threats to the survival of wild tigers: poaching tigers and hunting their prey. A model is developed to examine interactions between tigers and farm households living in and around tiger habitats. The analysis extends the existing literature on tiger demography, incorporating predator-prey interactions and exploring the sensitivity of tiger populations to key economic parameters. The analysis aims to contribute to policy debates on how best to protect one of the world' s most endangered wild cats

Climate change adaptation planning and cross-sectoral policy coherence in southern Africa

The post-2015 development agenda requires policy coherence, where achievement of development goals in one sector does not undermine the achievement of the goals of another. It also recognises that cross-cutting issues like adaptation to climate change need to be mainstreamed across multiple sectors. This paper presents a policy analysis using the cases of Malawi, Tanzania and Zambia. It analyses the water management and agricultural strategies and approaches identified in a variety of policies and plans. These include national sector policies for water and agriculture, National Development Plans, and climate change policies and strategies, including National Adaptation Programmes of Action and the Intended Nationally Determined Contributions submitted prior to the 2015 United Nations Framework Convention on Climate Change Conference of the Parties. It assesses the extent to which policies are coherent with one another with regard to their treatment of climate change adaptation using Qualitative Document Analysis. Findings identify that sector policies show some degree of cross-thematic coherence, in particular around their acknowledgement of the importance to address disaster management of floods and droughts. However, policy statements are typified by a relative lack of recognition of the need to develop supporting instruments and strategies that address climate adaptation needs over longer timeframes. Climate change policies explicitly call for significant investment in adaptation from the international community. Where coherence between sector and climate policies and strategies is strongest, the more recent climate policies largely repackage existing sectoral policy statements. These findings can be understood in the context of the uncertainty of climate change impacts for the longer term (for which a wider variety of adaptations are identified), alongside more event-driven disaster management planning where the impacts are more immediate and obviously evident. This prioritisation is also linked to development needs and the short-term nature of political cycles and economic gain. For climate-resilient policy decision-making to make further headway, we argue that governments need to embrace cross-sectoral planning more pro- actively in order to foster greater policy coherence and to deliver more climate resilient agriculture and water management

Assessment of Streamside Management Zones for Conserving Benthic Macroinvertebrate Communities Following Timber Harvest in Eastern Kentucky Headwater Catchments

Headwater streams generally comprise the majority of stream area in a watershed and can have a strong influence on downstream food webs. Our objective was to determine the effect of altering streamside management zone (SMZ) configurations on headwater aquatic insect communities. Timber harvests were implemented within six watersheds in eastern Kentucky. The SMZ configurations varied in width, canopy retention and best management practice (BMP) utilization at the watershed scale. Benthic macroinvertebrate samples collected one year before and four years after harvest indicated few differences among treatments, although post-treatment abundance was elevated in some of the treatment streams relative to the unharvested controls. Jaccard index values were similar across SMZ treatments after logging, indicating strong community overlap. These findings suggest that stream invertebrate communities did respond to the timber harvest, though not negatively. Results also suggest that SMZ criteria for aquatic habitats in steeply sloping topography, including at least 50 percent canopy retention and widths of at least 16.8 m, appear to be adequate for protecting benthic macroinvertebrate communities from logging impacts